phenytoin has been researched along with Acquired Immunodeficiency Syndrome in 9 studies
Acquired Immunodeficiency Syndrome: An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Serum phenytoin concentrations were investigated in 109 serum samples from 21 patients with the acquired immunodeficiency syndrome (AIDS) and in 1,231 serum samples from 557 control subjects during phenytoin therapy." | 7.69 | Therapeutic drug monitoring of phenytoin in patients with the acquired immunodeficiency syndrome. ( Beijnen, JH; Bult, A; Burger, DM; Koks, CH; Kraaijeveld, CL; Meenhorst, PL; Mulder, JW, 1994) |
| "Serum phenytoin concentrations were investigated in 109 serum samples from 21 patients with the acquired immunodeficiency syndrome (AIDS) and in 1,231 serum samples from 557 control subjects during phenytoin therapy." | 3.69 | Therapeutic drug monitoring of phenytoin in patients with the acquired immunodeficiency syndrome. ( Beijnen, JH; Bult, A; Burger, DM; Koks, CH; Kraaijeveld, CL; Meenhorst, PL; Mulder, JW, 1994) |
| "In particular, in patients with AIDS who are more susceptible for adverse drug reactions and who are simultaneously receiving a variety of drugs with a considerable potential of cutaneous side effects, therapy cannot be withhold for lack of therapeutic alternatives." | 1.29 | [Drug-induced Stevens-Johnson syndrome in a patient with AIDS]. ( Bircher, A; Haefeli, WE; Leib, SL; Lüscher, TF; Schlienger, RG, 1993) |
| "Seizures were the presenting symptom of HIV-related illness in 18 patients, six of whom developed no other HIV-related illness until at least four months after the first seizure." | 1.28 | New-onset seizures associated with human immunodeficiency virus infection: causation and clinical features in 100 cases. ( Holtzman, DM; Kaku, DA; So, YT, 1989) |
| "Acquired immunodeficiency syndrome (AIDS), with its attendant sequelae of opportunistic infections and aggressive lymphatic malignancies, continues to dominate the world's medical literature." | 1.27 | Phenytoin hypersensitivity with pulmonary involvement in a hemophiliac patient with human immunodeficiency virus infection. ( Amundson, D; Hostettler, C; O'Connor, S, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pfeffer, G | 1 |
| Prout, A | 1 |
| Hooge, J | 1 |
| Maguire, J | 1 |
| Soto-Hernández, JL | 1 |
| Moreno-Andrade, T | 1 |
| Góngora-Rivera, F | 1 |
| Ramírez-Crescencio, MA | 1 |
| Burger, DM | 1 |
| Meenhorst, PL | 1 |
| Mulder, JW | 1 |
| Kraaijeveld, CL | 1 |
| Koks, CH | 1 |
| Bult, A | 1 |
| Beijnen, JH | 1 |
| Schlienger, RG | 1 |
| Haefeli, WE | 1 |
| Bircher, A | 1 |
| Leib, SL | 1 |
| Lüscher, TF | 1 |
| Cone, LA | 1 |
| Woodard, DR | 1 |
| Simmons, JC | 1 |
| Sonnenshein, MA | 1 |
| Holtzman, DM | 1 |
| Kaku, DA | 1 |
| So, YT | 1 |
| Lehr, HA | 2 |
| Zimmer, JP | 2 |
| Hostettler, C | 1 |
| Amundson, D | 1 |
| O'Connor, S | 1 |
| Kern, W | 1 |
9 other studies available for phenytoin and Acquired Immunodeficiency Syndrome
| Article | Year |
|---|---|
Biopsy-proven immune reconstitution syndrome in a patient with AIDS and cerebral toxoplasmosis.
Topics: Acquired Immunodeficiency Syndrome; Adult; Animals; Antiretroviral Therapy, Highly Active; Biopsy; C | 2009 |
Nocardia abscess during treatment of brain toxoplasmosis in a patient with aids, utility of proton MR spectroscopy and diffusion-weighted imaging in diagnosis.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-Bacterial Agents; Anti-Retroviral Agents; Anticonvul | 2006 |
Therapeutic drug monitoring of phenytoin in patients with the acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Age Factors; Body Weight; Drug Interactions; Drug Monitor | 1994 |
[Drug-induced Stevens-Johnson syndrome in a patient with AIDS].
Topics: Acquired Immunodeficiency Syndrome; Humans; Male; Middle Aged; Phenytoin; Pyrimethamine; Stevens-Joh | 1993 |
Drug interactions in patients with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; Clofazimine; Drug Interactions; Humans; Male; Phenytoin; | 1992 |
New-onset seizures associated with human immunodeficiency virus infection: causation and clinical features in 100 cases.
Topics: Acquired Immunodeficiency Syndrome; Adult; Brain Diseases; Electroencephalography; Follow-Up Studies | 1989 |
[Diphenylhydantoin in the prevention and therapy of AIDS?].
Topics: Acquired Immunodeficiency Syndrome; Deltaretrovirus; Humans; Lymphocytes; Phenytoin; Receptors, Viru | 1986 |
Phenytoin hypersensitivity with pulmonary involvement in a hemophiliac patient with human immunodeficiency virus infection.
Topics: Acquired Immunodeficiency Syndrome; Adult; Drug Hypersensitivity; Female; Hemophilia A; Humans; Phen | 1987 |
[Diphenylhydantoin in AIDS].
Topics: Acquired Immunodeficiency Syndrome; Adult; Humans; Male; Phenytoin | 1986 |