Page last updated: 2024-10-21

phenytoin and Ache

phenytoin has been researched along with Ache in 71 studies

Research Excerpts

ExcerptRelevanceReference
"We reviewed patients who attended the emergency department of a tertiary hospital between 2012 and 2020 for exacerbations of trigeminal neuralgia pain and were treated with either intravenous phenytoin or lacosamide for the first time."9.22Intravenous lacosamide and phenytoin for the treatment of acute exacerbations of trigeminal neuralgia: A retrospective analysis of 144 cases. ( Campoy, S; Huerta-Villanueva, M; Muñoz-Vendrell, A; Sala-Padró, J; Teixidor, S, 2022)
"In view of the reports that phenytoin and honey are useful in the healing of wounds, a comparison of their topical use in the treatment of chronic leg ulcers was carried out."9.09A comparison of topical honey and phenytoin in the treatment of chronic leg ulcers. ( Olabanji, JK; Oluwatosin, OA; Oluwatosin, OM; Onyechi, HU; Tijani, LA, 2000)
"The efficacy of phenytoin (PHT), buprenorphine (Bu), and Bu+PHT for the relief of cancer pain of various etiologies was evaluated in a randomized, double-blind study of 3 groups, each comprised of 25 patients."9.07Phenytoin as a coanalgesic in cancer pain. ( Kumar, M; Singh, G; Singh, GP; Yajnik, S, 1992)
"In this study, we investigated the effects of fosphenytoin (fPHT), a water-soluble prodrug of phenytoin, on the pain responses of a mouse herpes zoster (HZ) pain model."8.12Fosphenytoin Alleviates Herpes Simplex Virus Infection-Induced Provoked and Spontaneous Pain-Like Behaviors in Mice. ( Arai, S; Inoue, A; Kitada, Y; Nagashima, R; Ogata, T; Shiraki, K; Takasaki, I; Ueda, T, 2022)
"Purple glove syndrome is an uncommon but dreaded complication of intravenous phenytoin administration characterised by pain, oedema and purple-blue discolouration of the limb distal to the site of injection."7.78Purple glove syndrome: a dreadful complication of intravenous phenytoin administration. ( Garg, RK; Lalla, R; Malhotra, HS; Sahu, R, 2012)
"Purple glove syndrome (PGS) is a rare complication of intravenous phenytoin use that typically presents with pain, edema, and discoloration at the injection site that spreads to the distal limb."7.74Purple glove syndrome following intravenous phenytoin administration. ( Chokshi, R; Mehta, NN; Mohler, E; Openshaw, J, 2007)
" For treating trigeminal neuralgia, carbamazepine had a combined number needed to treat of 2."6.17Anticonvulsant drugs for management of pain: a systematic review. ( Carroll, D; Jadad, AR; McQuay, H; Moore, A; Wiffen, P, 1995)
"Fosphenytoin is a phosphate ester prodrug of phenytoin that is significantly better tolerated parenterally than phenytoin in the treatment of epilepsy."5.31Fosphenytoin: an intravenous option for the management of acute trigeminal neuralgia crisis. ( Cheshire, WP, 2001)
"Twenty-nine complications were burning pain at the IV site, and 36 were related to excessive total dose of phenytoin and resultant drug intoxication."5.27Complications of intravenous phenytoin for acute treatment of seizures. Recommendations for usage. ( Drury, LR; Earnest, MP; Marx, JA, 1983)
"We reviewed patients who attended the emergency department of a tertiary hospital between 2012 and 2020 for exacerbations of trigeminal neuralgia pain and were treated with either intravenous phenytoin or lacosamide for the first time."5.22Intravenous lacosamide and phenytoin for the treatment of acute exacerbations of trigeminal neuralgia: A retrospective analysis of 144 cases. ( Campoy, S; Huerta-Villanueva, M; Muñoz-Vendrell, A; Sala-Padró, J; Teixidor, S, 2022)
"AVO cream significantly accelerates biological healing of chronic wounds and helps to reduce pain severity with a higher efficacy compared with phenytoin cream."5.20Comparative trial of Aloe vera/olive oil combination cream versus phenytoin cream in the treatment of chronic wounds. ( Beiraghdar, F; Izadi, M; Jonaidi-Jafari, N; Panahi, Y; Rezaee, R; Sahebkar, A; Sayyadi, N; Zamani, A, 2015)
"In view of the reports that phenytoin and honey are useful in the healing of wounds, a comparison of their topical use in the treatment of chronic leg ulcers was carried out."5.09A comparison of topical honey and phenytoin in the treatment of chronic leg ulcers. ( Olabanji, JK; Oluwatosin, OA; Oluwatosin, OM; Onyechi, HU; Tijani, LA, 2000)
"The efficacy of phenytoin (PHT), buprenorphine (Bu), and Bu+PHT for the relief of cancer pain of various etiologies was evaluated in a randomized, double-blind study of 3 groups, each comprised of 25 patients."5.07Phenytoin as a coanalgesic in cancer pain. ( Kumar, M; Singh, G; Singh, GP; Yajnik, S, 1992)
"In this study, we investigated the effects of fosphenytoin (fPHT), a water-soluble prodrug of phenytoin, on the pain responses of a mouse herpes zoster (HZ) pain model."4.12Fosphenytoin Alleviates Herpes Simplex Virus Infection-Induced Provoked and Spontaneous Pain-Like Behaviors in Mice. ( Arai, S; Inoue, A; Kitada, Y; Nagashima, R; Ogata, T; Shiraki, K; Takasaki, I; Ueda, T, 2022)
" Most crisis episodes managed with intravenous phenytoin reached total pain relief."4.12Treatment of acute exacerbations of trigeminal neuralgia in the emergency department: A retrospective case series. ( Abreu, P; Costa, A; Gomes, A; Pinto, M; Pinto, MJ, 2022)
"Purple glove syndrome is an uncommon but dreaded complication of intravenous phenytoin administration characterised by pain, oedema and purple-blue discolouration of the limb distal to the site of injection."3.78Purple glove syndrome: a dreadful complication of intravenous phenytoin administration. ( Garg, RK; Lalla, R; Malhotra, HS; Sahu, R, 2012)
"Purple glove syndrome (PGS) is a rare complication of intravenous phenytoin use that typically presents with pain, edema, and discoloration at the injection site that spreads to the distal limb."3.74Purple glove syndrome following intravenous phenytoin administration. ( Chokshi, R; Mehta, NN; Mohler, E; Openshaw, J, 2007)
"PGS is a poorly understood, potentially serious local complication of IV phenytoin administration characterized by progressive distal limb edema, discoloration, and pain."3.70Incidence and clinical consequence of the purple glove syndrome in patients receiving intravenous phenytoin. ( Cascino, GD; Hanna, DR; O'Brien, TJ; So, EL, 1998)
"" These patients described their prodromal pain as a toothache or sinusitis-like pain lasting up to several hours, sometimes triggered by jaw movements or by drinking hot or cold liquids."3.68Pre-trigeminal neuralgia. ( Fromm, GH; Graff-Radford, SB; Sweet, WH; Terrence, CF, 1990)
"Phenytoin (PHT) has been widely used intravenously for the treatment of seizures since 1956, and for many years, it has been considered first-line therapy for status epilepticus."2.70A prospective study of the incidence of the purple glove syndrome. ( Anandan, JV; Barkley, GL; Burneo, JG, 2001)
"Trigeminal neuralgia is a sudden, unilateral, brief, stabbing, recurrent pain in the distribution of one or more branches of the fifth cranial nerve."2.45Trigeminal neuralgia. ( Linskey, ME; Zakrzewska, JM, 2009)
"Gabapentin has demonstrated efficacy, specifically in painful diabetic neuropathy and postherpetic neuralgia."2.41Use of anticonvulsants for treatment of neuropathic pain. ( Backonja, MM, 2002)
"Phenytoin has a narrow therapeutic range and exhibits concentration-dependent kinetics within this therapeutic window."1.35Elevated thyroid-stimulating hormone in a 65-year-old patient with phenytoin toxicity. ( Collins, RJ, 2008)
"Fosphenytoin is a phosphate ester prodrug of phenytoin that is significantly better tolerated parenterally than phenytoin in the treatment of epilepsy."1.31Fosphenytoin: an intravenous option for the management of acute trigeminal neuralgia crisis. ( Cheshire, WP, 2001)
"Twenty-nine complications were burning pain at the IV site, and 36 were related to excessive total dose of phenytoin and resultant drug intoxication."1.27Complications of intravenous phenytoin for acute treatment of seizures. Recommendations for usage. ( Drury, LR; Earnest, MP; Marx, JA, 1983)
" The dosing method accurately achieved desired phenytoin concentrations (predicted mean +/- S."1.27Efficacy of individualized phenytoin sodium loading doses administered by intravenous infusion. ( Dela Cruz, FG; Fischer, JH; Kanter, MZ; Leikin, JB, 1988)
"Ictal and post-ictal confusional states of 24 h or more duration (up to 7-8 days) were noted in 11 patients (14%)."1.26Epileptic seizures in the elderly: II. Diagnostic problems. ( Caird, FI; Godfrey, JW; Roberts, MA, 1982)
" Unit dose packaging is used because the oral solid dosage forms (including placebos) are made to look alike."1.25Drug use and distribution in a pain rehabilitation center. ( Beckner, TF; Idsvoog, P, 1975)

Research

Studies (71)

TimeframeStudies, this research(%)All Research%
pre-199035 (49.30)18.7374
1990's12 (16.90)18.2507
2000's15 (21.13)29.6817
2010's6 (8.45)24.3611
2020's3 (4.23)2.80

Authors

AuthorsStudies
Yang, J1
Gharagozloo, P1
Yao, J1
Ilyin, VI1
Carter, RB1
Nguyen, P1
Robledo, S1
Woodward, RM1
Hogenkamp, DJ1
Yogeeswari, P1
Ragavendran, JV1
Sriram, D1
Nageswari, Y1
Kavya, R1
Sreevatsan, N1
Vanitha, K1
Stables, J1
Salomé, C1
Salomé-Grosjean, E1
Stables, JP1
Kohn, H1
Czopek, A1
Byrtus, H1
Zagórska, A1
Rychtyk, J1
Góra, M1
Sałat, K1
Rapacz, A1
Obniska, J1
Takasaki, I1
Nagashima, R1
Ueda, T1
Ogata, T1
Inoue, A1
Shiraki, K1
Kitada, Y1
Arai, S1
Muñoz-Vendrell, A1
Teixidor, S1
Sala-Padró, J1
Campoy, S1
Huerta-Villanueva, M1
Pinto, MJ1
Gomes, A1
Pinto, M1
Abreu, P1
Costa, A1
Dudley, ES1
Boivin, GP1
MacIsaac, R1
Brust, T1
Panahi, Y1
Izadi, M1
Sayyadi, N1
Rezaee, R1
Jonaidi-Jafari, N1
Beiraghdar, F1
Zamani, A1
Sahebkar, A1
Collins, RJ1
Zakrzewska, JM1
Linskey, ME1
Lalla, R1
Malhotra, HS1
Garg, RK1
Sahu, R1
Backonja, MM1
GREEN, JB1
KONG, Y1
HEYMAN, A1
ENTMAN, ML1
MCINTOSH, HD1
Hobgood, C1
Hevia, A1
Hinchey, P1
Ko, SH1
Jochnowitz, N1
Lenkowski, PW1
Batts, TW1
Davis, GC1
Martin, WJ1
Brown, ML1
Patel, MK1
Chokshi, R1
Openshaw, J1
Mehta, NN1
Mohler, E1
Loh, KY1
Kew, ST1
Soslow, AR1
Swerdlow, M2
Cundill, JG1
Godfrey, JW1
Roberts, MA1
Caird, FI1
Earnest, MP1
Marx, JA1
Drury, LR1
Rushton, JG1
Stevens, JC1
Miller, RH1
Aldrete, JA1
Ghaly, R1
McQuay, H1
Carroll, D1
Jadad, AR1
Wiffen, P1
Moore, A1
Webb, J1
Kamali, F1
O'Brien, TJ1
Cascino, GD1
So, EL1
Hanna, DR1
Scholz, J1
Vieregge, P1
Moser, A1
Coplin, WM1
Rhoney, DH1
Lyons, EA1
Murry, KR1
Chojnowska, E1
Anderson, GD1
Lin, Y1
Temkin, NR1
Fischer, JH2
Winn, HR1
Yoshikawa, H1
Abe, T1
Oda, Y1
Oluwatosin, OM1
Olabanji, JK1
Oluwatosin, OA1
Tijani, LA1
Onyechi, HU1
Cheshire, WP1
Burneo, JG1
Anandan, JV1
Barkley, GL1
Sheth, KJ1
Bernhard, GC1
Chadda, VS1
Mathur, MS1
Wilkinson, HA2
Peppercorn, MA1
Herzog, AG1
Dichter, MA1
Mayman, CI1
Walson, P1
Trinca, C1
Bressler, R1
Beckner, TF1
Idsvoog, P1
Eadie, MJ1
Fong, GR1
Yajnik, S1
Singh, GP1
Singh, G1
Kumar, M1
Skelton, WP1
Skelton, NK1
Petrides, PE1
Bartl, R1
Büchele, W1
Moser, E1
Ronin, DI1
Wu, YC1
Sahgal, V1
MacLean, IC1
Bosker, H1
Jordan, RD1
Sindet-Pedersen, S1
Koole, R1
Fromm, GH1
Graff-Radford, SB1
Terrence, CF1
Sweet, WH2
Chaturvedi, SK1
Dela Cruz, FG1
Kanter, MZ1
Leikin, JB1
Stella, VJ1
Charman, WN1
Naringrekar, VH1
Yaari, Y1
Devor, M1
Cantor, FK1
Igata, A1
Mladinich, EK1
Chikhani, P1
Greenbaum, DS1
Ferguson, RK1
Kater, LA1
Kuiper, DH1
Rosen, LW1
Lockman, LA1
Hunninghake, DB1
Krivit, W1
Desnick, RJ1
Shibasaki, H2
Kuroiwa, Y2
Poley, JR1
Bhatia, M1
Christiansen, J1
Dam, M1
Klinefelter, HF1
Greene, CA1
Pauli, LL1
Livingston, S1
Ekbom, K1
Babb, RR1
Eckman, PB1
Wepsic, JG1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Examining the Efficacy of Low Intensity Low Frequency Surface Acoustic Wave Ultrasound(LILF/SAWU) in Trigeminal Neuralgia Pain[NCT01447108]Phase 416 participants (Actual)Interventional2011-11-30Completed
Erenumab as a Therapeutic Approach for the Management of Trigeminal Neuropathic Pain (TNP)[NCT05142228]Phase 25 participants (Actual)Interventional2022-04-01Terminated (stopped due to Low enrollment rate)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for phenytoin and Ache

ArticleYear
Intravenous lacosamide and phenytoin for the treatment of acute exacerbations of trigeminal neuralgia: A retrospective analysis of 144 cases.
    Cephalalgia : an international journal of headache, 2022, Volume: 42, Issue:10

    Topics: Female; Humans; Lacosamide; Male; Middle Aged; Pain; Phenytoin; Retrospective Studies; Treatment Out

2022
Trigeminal neuralgia.
    BMJ clinical evidence, 2009, Mar-12, Volume: 2009

    Topics: Humans; Ophthalmic Solutions; Pain; Pain Measurement; Phenytoin; Radiosurgery; Trigeminal Ganglion;

2009
Use of anticonvulsants for treatment of neuropathic pain.
    Neurology, 2002, Sep-10, Volume: 59, Issue:5 Suppl 2

    Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid;

2002
Anticonvulsant drugs for management of pain: a systematic review.
    BMJ (Clinical research ed.), 1995, Oct-21, Volume: 311, Issue:7012

    Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diabetic Neuropathies; Humans; Pain; Phenytoin; Treatmen

1995
Prodrugs. Do they have advantages in clinical practice?
    Drugs, 1985, Volume: 29, Issue:5

    Topics: Absorption; Adrenal Cortex Hormones; Blood-Brain Barrier; Chloramphenicol; Drug Stability; Drug Ther

1985
[Ataxia associated with infections and toxicosis].
    Nihon rinsho. Japanese journal of clinical medicine, 1971, Volume: 29, Issue:8

    Topics: Abdomen; Adult; Animals; Ataxia; Cerebellar Ataxia; Cerebrovascular Disorders; Demyelinating Disease

1971

Trials

12 trials available for phenytoin and Ache

ArticleYear
Comparative trial of Aloe vera/olive oil combination cream versus phenytoin cream in the treatment of chronic wounds.
    Journal of wound care, 2015, Volume: 24, Issue:10

    Topics: Aloe; Anti-Infective Agents; Chronic Disease; Double-Blind Method; Drug Therapy, Combination; Humans

2015
Anticonvulsant drugs for management of pain: a systematic review.
    BMJ (Clinical research ed.), 1995, Oct-21, Volume: 311, Issue:7012

    Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diabetic Neuropathies; Humans; Pain; Phenytoin; Treatmen

1995
Analgesic effects of lamotrigine and phenytoin on cold-induced pain: a crossover placebo-controlled study in healthy volunteers.
    Pain, 1998, Volume: 76, Issue:3

    Topics: Adult; Anticonvulsants; Blood Pressure; Cold Temperature; Cross-Over Studies; Double-Blind Method; F

1998
A comparison of topical honey and phenytoin in the treatment of chronic leg ulcers.
    African journal of medicine and medical sciences, 2000, Volume: 29, Issue:1

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Child; Chronic Disease; Drug

2000
A prospective study of the incidence of the purple glove syndrome.
    Epilepsia, 2001, Volume: 42, Issue:9

    Topics: Aged; Anticonvulsants; Edema; Epilepsy; Female; Forearm; Hand; Humans; Incidence; Infusions, Intrave

2001
Double blind study of the effects of diphenylhydantoin sodium on diabetic neuropathy.
    The Journal of the Association of Physicians of India, 1978, Volume: 26, Issue:5

    Topics: Adult; Aged; Clinical Trials as Topic; Diabetic Neuropathies; Double-Blind Method; Female; Humans; M

1978
Phenytoin as a coanalgesic in cancer pain.
    Journal of pain and symptom management, 1992, Volume: 7, Issue:4

    Topics: Adult; Buprenorphine; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Neoplasms; Pain;

1992
Neuroleptics in painful thiamine deficiency neuropathy.
    Southern medical journal, 1991, Volume: 84, Issue:11

    Topics: Aged; Carbamazepine; Electromyography; Humans; Male; Middle Aged; Neural Conduction; Pain; Periphera

1991
A controlled therapeutic study of the irritable-bowel syndrome: effect of diphenylhydantoin.
    The New England journal of medicine, 1973, Jan-04, Volume: 288, Issue:1

    Topics: Adult; Aged; Clinical Trials as Topic; Colonic Diseases, Functional; Female; Humans; Male; Middle Ag

1973
Relief of pain of Fabry's disease by diphenylhydantoin.
    Neurology, 1973, Volume: 23, Issue:8

    Topics: Adolescent; Adult; Aspirin; Ceramides; Clinical Trials as Topic; Evaluation Studies as Topic; Female

1973
Painful tonic seizure in multiple sclerosis.
    Archives of neurology, 1974, Volume: 30, Issue:1

    Topics: Adult; Animals; Brain Stem; Carbamazepine; Cerebellum; Cerebral Cortex; Clinical Trials as Topic; De

1974
Painful tonic seizure in multiple sclerosis treatment with diphenylhydantoin and carbamazepine.
    Folia psychiatrica et neurologica japonica, 1968, Volume: 22, Issue:2

    Topics: Adult; Carbamazepine; Dibenzazepines; Electrocardiography; Electroencephalography; Female; Humans; M

1968

Other Studies

54 other studies available for phenytoin and Ache

ArticleYear
3-(4-phenoxyphenyl)pyrazoles: a novel class of sodium channel blockers.
    Journal of medicinal chemistry, 2004, Mar-11, Volume: 47, Issue:6

    Topics: Analgesics; Animals; Cell Line; Humans; Male; Pain; Patch-Clamp Techniques; Peripheral Nervous Syste

2004
Discovery of 4-aminobutyric acid derivatives possessing anticonvulsant and antinociceptive activities: a hybrid pharmacophore approach.
    Journal of medicinal chemistry, 2007, May-17, Volume: 50, Issue:10

    Topics: Analgesics; Animals; Anticonvulsants; Disease Models, Animal; gamma-Aminobutyric Acid; Hyperalgesia;

2007
Merging the structural motifs of functionalized amino acids and alpha-aminoamides: compounds with significant anticonvulsant activities.
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Acetamides; Alanine; Amides; Amino Acids; Animals; Anticonvulsants; Benzylamines; Drug Evaluation, P

2010
Synthesis and pharmacological evaluation of novel N-Mannich bases derived from 5,5-diphenyl and 5,5-di(propan-2-yl)imidazolidine-2,4-dione core.
    Bioorganic & medicinal chemistry letters, 2019, 08-15, Volume: 29, Issue:16

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Imidazolidines;

2019
Fosphenytoin Alleviates Herpes Simplex Virus Infection-Induced Provoked and Spontaneous Pain-Like Behaviors in Mice.
    Biological & pharmaceutical bulletin, 2022, Mar-01, Volume: 45, Issue:3

    Topics: Animals; Herpes Simplex; Herpesvirus 1, Human; Hyperalgesia; Mice; Pain; Phenytoin

2022
Treatment of acute exacerbations of trigeminal neuralgia in the emergency department: A retrospective case series.
    Headache, 2022, Volume: 62, Issue:8

    Topics: Adult; Emergency Service, Hospital; Female; Humans; Male; Middle Aged; Pain; Phenytoin; Retrospectiv

2022
Evaluation of a Commercially Available Euthanasia Solution as a Voluntarily Ingested Euthanasia Agent in Laboratory Mice.
    Journal of the American Association for Laboratory Animal Science : JAALAS, 2018, 01-01, Volume: 57, Issue:1

    Topics: Administration, Oral; Animals; Euthanasia, Animal; Female; Laboratory Animal Science; Male; Mice; Pa

2018
Painful Proximal Weakness and HyperCKemia Related to Intravenous Loading of Phenytoin.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2018, Volume: 45, Issue:6

    Topics: Administration, Intravenous; Anticonvulsants; Creatine Kinase; Female; Humans; Middle Aged; Pain; Ph

2018
Elevated thyroid-stimulating hormone in a 65-year-old patient with phenytoin toxicity.
    The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists, 2008, Volume: 23, Issue:8

    Topics: Aged; Anticonvulsants; Drug Monitoring; Humans; Male; Pain; Phenytoin; Sinusitis; Thyrotropin

2008
Purple glove syndrome: a dreadful complication of intravenous phenytoin administration.
    BMJ case reports, 2012, Aug-24, Volume: 2012

    Topics: Administration, Intravenous; Adult; Anticonvulsants; Drug Eruptions; Edema; Encephalitis; Fatal Outc

2012
Dilantin in the treatment of lightning pains.
    Neurology, 1961, Volume: 11

    Topics: Humans; Hydantoins; Lightning; Pain; Phenytoin; Tabes Dorsalis

1961
GLOSSOPHARYNGEAL NEURALGIA ASSOCIATED WITH BRADYCARDIA, SYNCOPE, AND SEIZURES.
    Circulation, 1964, Volume: 30

    Topics: Atropine; Bradycardia; Drug Therapy; Electrocardiography; Geriatrics; Glossopharyngeal Nerve; Glosso

1964
Profiles in patient safety: when an error occurs.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2004, Volume: 11, Issue:7

    Topics: Acetates; Aged; Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Diabetic Neuropath

2004
Reversal of neuropathic pain by alpha-hydroxyphenylamide: a novel sodium channel antagonist.
    Neuropharmacology, 2006, Volume: 50, Issue:7

    Topics: Action Potentials; Amides; Animals; Dose-Response Relationship, Drug; Ganglia, Spinal; Male; Pain; P

2006
Purple glove syndrome following intravenous phenytoin administration.
    Vascular medicine (London, England), 2007, Volume: 12, Issue:1

    Topics: Aged; Anticonvulsants; Cyanosis; Edema; Epilepsy, Tonic-Clonic; Hand; Humans; Infusions, Intravenous

2007
A painful gum.
    Australian family physician, 2007, Volume: 36, Issue:9

    Topics: Anticonvulsants; Epilepsy; Family Practice; Gingiva; Gingival Hyperplasia; Humans; Hygiene; Male; Mi

2007
Psychomotor seizures.
    Annals of emergency medicine, 1984, Volume: 13, Issue:4

    Topics: Abdomen; Adult; Dizziness; Electroencephalography; Epilepsy, Temporal Lobe; Female; Humans; Pain; Ph

1984
The treatment of "shooting" pain.
    Postgraduate medical journal, 1980, Volume: 56, Issue:653

    Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Female; Humans; Male; Middle Aged; Pain; Phenytoin; V

1980
Anticonvulsant drugs used in the treatment of lancinating pain. A comparison.
    Anaesthesia, 1981, Volume: 36, Issue:12

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Chronic Disease; Clonazepam; Female; Humans

1981
Epileptic seizures in the elderly: II. Diagnostic problems.
    Age and ageing, 1982, Volume: 11, Issue:1

    Topics: Aged; Brain; Cerebral Infarction; Confusion; Dementia; Diagnosis, Differential; Electroencephalograp

1982
Complications of intravenous phenytoin for acute treatment of seizures. Recommendations for usage.
    JAMA, 1983, Feb-11, Volume: 249, Issue:6

    Topics: Adolescent; Adult; Aged; Cardiovascular Diseases; Crystallization; Female; Humans; Infusions, Parent

1983
Glossopharyngeal (vagoglossopharyngeal) neuralgia: a study of 217 cases.
    Archives of neurology, 1981, Volume: 38, Issue:4

    Topics: Adolescent; Adult; Carbamazepine; Cocaine; Cranial Nerve Diseases; Geniculate Ganglion; Glossopharyn

1981
Delayed sympathetically maintained pain caused by electrical burn at the current's entry and exit sites.
    Journal of pain and symptom management, 1994, Volume: 9, Issue:8

    Topics: Adult; Autonomic Nerve Block; Burns, Electric; Exercise Therapy; Female; Humans; Pain; Palliative Ca

1994
Incidence and clinical consequence of the purple glove syndrome in patients receiving intravenous phenytoin.
    Neurology, 1998, Volume: 51, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Child; Edema; Female; Forearm; Hand; Hu

1998
Central pain as a manifestation of partial epileptic seizures.
    Pain, 1999, Volume: 80, Issue:1-2

    Topics: Adult; Anticonvulsants; Electroencephalography; Epilepsies, Partial; Female; Humans; Magnetic Resona

1999
Incidence and clinical consequence of the purple glove syndrome in patients receiving intravenous phenytoin.
    Neurology, 1999, Oct-22, Volume: 53, Issue:7

    Topics: Anticonvulsants; Edema; Extremities; Humans; Injections, Intravenous; Pain; Phenytoin

1999
Which intravenous sodium channel blocker for neuropathic pain?
    Anesthesia and analgesia, 2000, Volume: 90, Issue:4

    Topics: Humans; Pain; Phenytoin; Sodium Channel Blockers

2000
Incidence of intravenous site reactions in neurotrauma patients receiving valproate or phenytoin.
    The Annals of pharmacotherapy, 2000, Volume: 34, Issue:6

    Topics: Adult; Aged; Anticonvulsants; Brain Injuries; Chi-Square Distribution; Double-Blind Method; Female;

2000
Purple glove syndrome caused by oral administration of phenytoin.
    Journal of child neurology, 2000, Volume: 15, Issue:11

    Topics: Administration, Oral; Anticonvulsants; Child; Drug Overdose; Edema; Epilepsy; Extremities; Humans; M

2000
Fosphenytoin: an intravenous option for the management of acute trigeminal neuralgia crisis.
    Journal of pain and symptom management, 2001, Volume: 21, Issue:6

    Topics: Acute Disease; Aged; Aged, 80 and over; Female; Humans; Injections, Intravenous; Male; Pain; Palliat

2001
The arthropathy of Fabry disease.
    Arthritis and rheumatism, 1979, Volume: 22, Issue:7

    Topics: Adult; Fabry Disease; Finger Joint; Humans; Joints; Male; Neural Conduction; Pain; Phenytoin; Synovi

1979
Flashing pain syndrome.
    Journal of neurosurgery, 1977, Volume: 46, Issue:2

    Topics: Animals; Carbamazepine; Pain; Phenytoin; Primidone; Rats; Syndrome

1977
Abdominal epilepsy. A cause of abdominal pain in adults.
    JAMA, 1978, Nov-24, Volume: 240, Issue:22

    Topics: Abdomen; Adolescent; Adult; Diagnosis, Differential; Electroencephalography; Epilepsy; Female; Human

1978
New uses for phenytoin.
    JAMA, 1975, Sep-29, Volume: 233, Issue:13

    Topics: Arrhythmias, Cardiac; Diabetic Neuropathies; Digitalis Glycosides; Drug Evaluation; Epilepsy; Gastro

1975
Drug use and distribution in a pain rehabilitation center.
    American journal of hospital pharmacy, 1975, Volume: 32, Issue:3

    Topics: Adult; Amitriptyline; Barbiturates; Chronic Disease; Diet; Female; Formularies, Hospital as Topic; H

1975
The management of facial pain.
    The Medical journal of Australia, 1975, Aug-09, Volume: 2, Issue:6

    Topics: Bruxism; Carbamazepine; Diagnosis, Differential; Ergotamine; Face; Female; Herpes Zoster; Humans; Ma

1975
Letter: Drug use in a pain rehabilitation center.
    American journal of hospital pharmacy, 1975, Volume: 32, Issue:11

    Topics: Amitriptyline; Chronic Disease; Drug Combinations; Humans; Methadone; Pain; Phenytoin; Snake Venoms

1975
[Chief symptoms: bone pain and muscle weakness].
    Der Internist, 1991, Volume: 32, Issue:1

    Topics: Aged; Alkaline Phosphatase; Biopsy; Bone and Bones; Diagnosis, Differential; Epilepsy, Absence; Fema

1991
Intractable muscle pain syndrome, osteomalacia, and axonopathy in long-term use of phenytoin.
    Archives of physical medicine and rehabilitation, 1991, Volume: 72, Issue:10

    Topics: Aged; Humans; Male; Muscular Diseases; Nervous System Diseases; Osteomalacia; Pain; Phenytoin; Vitam

1991
The transmandibular implant: a 13-year survey of its use.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1991, Volume: 49, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Dental Implantation, Endosseous; Female; Follow-Up Studies; Gingival

1991
Pre-trigeminal neuralgia.
    Neurology, 1990, Volume: 40, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Carbamazepine; Diagnosis, Differential; Female; Humans; Jaw; Joint D

1990
Phenytoin in reflex sympathetic dystrophy.
    Pain, 1989, Volume: 36, Issue:3

    Topics: Adult; Humans; Male; Pain; Phenytoin; Reflex Sympathetic Dystrophy

1989
Efficacy of individualized phenytoin sodium loading doses administered by intravenous infusion.
    Clinical pharmacy, 1988, Volume: 7, Issue:3

    Topics: Adult; Aged; Blood Pressure; Emergencies; Female; Heart Rate; Humans; Infusions, Intravenous; Inject

1988
Phenytoin suppresses spontaneous ectopic discharge in rat sciatic nerve neuromas.
    Neuroscience letters, 1985, Jul-04, Volume: 58, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Male; Neuroma; Pain; Peripheral Nerve Injuries; Periphera

1985
Phenytoin treatment of thalamic pain.
    British medical journal, 1972, Dec-09, Volume: 4, Issue:5840

    Topics: Humans; Hypertension; Infarction; Male; Middle Aged; Neurologic Manifestations; Pain; Peripheral Ner

1972
Letter: Diphenylhydantoin in the Wallenberg syndrome.
    JAMA, 1974, Oct-21, Volume: 230, Issue:3

    Topics: Adult; Humans; Intracranial Embolism and Thrombosis; Lateral Medullary Syndrome; Male; Pain; Phenyto

1974
[Use of sodium phenytoin in the treatment of periodontal diseases].
    Actualites odonto-stomatologiques, 1972, Volume: 26, Issue:98

    Topics: Adult; Age Factors; Aged; Edema; Female; Gingival Hypertrophy; Humans; Male; Massage; Middle Aged; O

1972
Recurrent abdominal pain: recurrent controversy.
    Pediatrics, 1973, Volume: 52, Issue:1

    Topics: Abdomen; Child; Child, Preschool; Food Hypersensitivity; Humans; Migraine Disorders; Pain; Phenytoin

1973
Epileptic pain. An uncommon manifestation with localizing value.
    Neurology, 1973, Volume: 23, Issue:5

    Topics: Adenocarcinoma; Adult; Brain Neoplasms; Cerebral Angiography; Diazepam; Epilepsy; Female; Humans; Ma

1973
Influence of phenobarbital and diphenylhydantoin on plasma carbamazepine levels in patients with epilepsy.
    Acta neurologica Scandinavica, 1973, Volume: 49, Issue:4

    Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Depression, Chemical; Drug Therapy, Combination; Epil

1973
Precordial pain in an epileptic relic by dilantin.
    The Johns Hopkins medical journal, 1969, Volume: 124, Issue:1

    Topics: Angina Pectoris; Diagnosis, Differential; Electrocardiography; Epilepsy; Female; Humans; Middle Aged

1969
Carbamazepine in the treatment of tabetic lightning pains.
    Archives of neurology, 1972, Volume: 26, Issue:4

    Topics: Adult; Aged; Carbamazepine; Female; Humans; Male; Middle Aged; Pain; Phenytoin; Syphilis Serodiagnos

1972
Abdominal epilepsy.
    JAMA, 1972, Oct-02, Volume: 222, Issue:1

    Topics: Abdomen; Age Factors; Child; Electroencephalography; Epilepsy; Humans; Nausea; Pain; Phenytoin; Prog

1972
Relation of fiber size in trigeminal posterior root to conduction of impulses for pain and touch; production of analgesia without anesthesia in the effective treatment of trigeminal neuralgia.
    Transactions of the American Neurological Association, 1970, Volume: 95

    Topics: Analgesia; Dibenzazepines; Electrodes; Facial Neoplasms; Facial Neuralgia; Hot Temperature; Humans;

1970