phenytoin has been researched along with Acantholysis Bullosa in 36 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "We administered phenytoin (diphenylhydantoin) by mouth to 17 unselected patients to assess its ability to reduce blistering in recessive dystrophic epidermolysis bullosa (RDEB)." | 9.05 | Phenytoin therapy of recessive dystrophic epidermolysis bullosa. Clinical trial and proposed mechanism of action on collagenase. ( Bauer, EA; Cooper, TW; Esterly, NB; Tucker, DR, 1980) |
| "Oral phenytoin has been shown to be effective in the treatment of recessive dystrophic epidermolysis bullosa (EB)." | 7.67 | Efficacy of systemic phenytoin in the treatment of junctional epidermolysis bullosa. ( Fine, JD; Johnson, L, 1988) |
| "We administered phenytoin (diphenylhydantoin) by mouth to 17 unselected patients to assess its ability to reduce blistering in recessive dystrophic epidermolysis bullosa (RDEB)." | 5.05 | Phenytoin therapy of recessive dystrophic epidermolysis bullosa. Clinical trial and proposed mechanism of action on collagenase. ( Bauer, EA; Cooper, TW; Esterly, NB; Tucker, DR, 1980) |
| "We reviewed 49,902 dermatology cases seen in our clinic over a 7-year period (1984 through 1990) and carried out a therapeutic trial of oral phenytoin in three severe cases of epidermolysis bullosa dystrophica (Recessive dystrophic type)." | 3.68 | Epidermolysis bullosa in the eastern province of Saudi Arabia. ( Abahussein, AA; al-Zayir, AA; Mostafa, WZ; Okoro, AN, 1993) |
| " Our therapy consists of a combination of the following principles: (a) inhibition of collagenase formation by oral phenytoin to reduce epithelial detachment; (b) pureed or semiliquid food because minor trauma by hard food particles may induce blistering and result in scarring of the upper esophagus, and larger food particles may obstruct an esophageal stricture; (c) avoidance of tangential shearing forces induced by bougienage and endoscopy and instead use of inflatable dilatator balloons which produce vertical pressure that seems to be less harmful; and (d) long-term nasogastric tube feeding, which may relieve even tight strictures." | 3.67 | Management of esophageal stenosis in recessive dystrophic epidermolysis bullosa. ( Anton-Lamprecht, I; Baldauf, G; Feurle, GE; Schulte-Braucks, T; Weidauer, H, 1984) |
| "To assess the potential short- and long-term efficacy of phenytoin in treating recessive dystrophic epidermolysis bullosa (RDEB), we treated 22 patients with therapeutic doses of oral phenytoin (blood level, 8 to 10 micrograms/mL) for periods ranging from eight to 99 weeks." | 3.67 | Therapeutic efficacy of phenytoin in recessive dystrophic epidermolysis. A comparison of short- and long-term treatment. ( Bauer, EA; Cooper, TW, 1984) |
| "Oral phenytoin has been shown to be effective in the treatment of recessive dystrophic epidermolysis bullosa (EB)." | 3.67 | Efficacy of systemic phenytoin in the treatment of junctional epidermolysis bullosa. ( Fine, JD; Johnson, L, 1988) |
| " It can cause generalized cutaneous eruptions that include a maculopapular exanthem, Stevens-Johnson syndrome, generalized exfoliative dermatitis, toxic epidermal necrolysis, vasculitis, and fixed-drug eruptions." | 2.42 | Phenytoin in cutaneous medicine: its uses, mechanisms and side effects. ( Scheinfeld, N, 2003) |
| "If oesophageal strictures were present, endoscopy and bouginage with corticosteroid prophylaxis during the quiescent phase of the disease was a safe and useful procedure." | 1.28 | Management of oesophageal stenosis in epidermolysis bullosa dystrophica. ( Eisenberg, M; Kern, IB; Willis, S, 1989) |
| "Phenytoin has been shown to reduce the excessive production of collagenase and thereby to diminish blistering of skin and mucous membranes and stricture formation of the oesophagus." | 1.27 | [Therapy of esophageal stenoses in recessive epidermolysis bullosa dystrophica]. ( Anton-Lamprecht, I; Baldauf, G; Feurle, GE; Weidauer, H, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (88.89) | 18.7374 |
| 1990's | 2 (5.56) | 18.2507 |
| 2000's | 1 (2.78) | 29.6817 |
| 2010's | 1 (2.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Oztekin, O | 1 |
| Kalay, S | 1 |
| Tezel, G | 1 |
| Basaran, E | 1 |
| Bassorgun, I | 1 |
| Akcakus, M | 1 |
| Oygur, N | 1 |
| Scheinfeld, N | 1 |
| Jacobs, AH | 1 |
| Bauer, EA | 4 |
| Cooper, TW | 3 |
| Tucker, DR | 1 |
| Esterly, NB | 1 |
| Kero, M | 2 |
| Palotie, A | 1 |
| Peltonen, L | 1 |
| Feurle, GE | 2 |
| Weidauer, H | 2 |
| Baldauf, G | 3 |
| Schulte-Braucks, T | 1 |
| Anton-Lamprecht, I | 4 |
| Armoni, M | 2 |
| Schlesinger, M | 2 |
| Metzker, A | 2 |
| Guill, MF | 2 |
| Wray, BB | 1 |
| Rogers, RB | 2 |
| Yancey, KB | 2 |
| Allen, BS | 2 |
| Wirth, H | 1 |
| Nesch, A | 1 |
| Ostapowicz, B | 1 |
| Gedde-Dahl, T | 1 |
| Bergfeld, WF | 1 |
| Orlowski, JP | 1 |
| Bandmann, HJ | 1 |
| Perwein, E | 1 |
| Dodson, WE | 1 |
| Abahussein, AA | 1 |
| al-Zayir, AA | 1 |
| Mostafa, WZ | 1 |
| Okoro, AN | 1 |
| Eisenberg, M | 2 |
| Stevens, LH | 1 |
| Schofield, PJ | 1 |
| Seitz, HK | 1 |
| Egerer, G | 1 |
| Sina, R | 1 |
| Hartschuh, W | 1 |
| Kommerell, B | 1 |
| Cozzani, E | 1 |
| Gnone, M | 1 |
| Arioni, C | 1 |
| Cipriani, C | 1 |
| Kern, IB | 1 |
| Willis, S | 1 |
| Tabas, M | 1 |
| Fine, JD | 2 |
| Krieg, T | 1 |
| Schurig, V | 1 |
| Braun-Falco, O | 1 |
| Keefe, M | 1 |
| Wakeel, RA | 1 |
| Dick, DC | 1 |
| Sybert, VP | 1 |
| Pearson, RW | 1 |
| Paller, AS | 1 |
| Johnson, L | 1 |
| Cunnane, SC | 1 |
| Kent, ET | 1 |
| McAdoo, KR | 1 |
| Caldwell, D | 1 |
| Lin, AN | 1 |
| Carter, DM | 1 |
| Pini, LA | 1 |
| Girolomoni, G | 1 |
| Coppini, M | 1 |
| Pincelli, C | 1 |
| Schiazza, L | 1 |
| Rampini, E | 1 |
| Occella, C | 1 |
| Nemelka, O | 1 |
| Haber, RM | 1 |
| Hanna, W | 1 |
| Ramsay, CA | 1 |
| Boxall, LB | 1 |
| Vardy, PA | 1 |
| Weismann, K | 1 |
5 reviews available for phenytoin and Acantholysis Bullosa
| Article | Year |
|---|---|
Phenytoin in cutaneous medicine: its uses, mechanisms and side effects.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Dermatologic Agents; Drug Hypersensitivity; Drug Inter | 2003 |
[Epidermolysis bullosa and collagenoses].
Topics: Epidermolysis Bullosa; Humans; Microbial Collagenase; Phenytoin; Prognosis; Vitamin E | 1989 |
Epidermolysis bullosa. Clinical aspects, pathology, and recent advances in research.
Topics: Anti-Bacterial Agents; Antibodies, Monoclonal; Antigens; Basement Membrane; DNA, Recombinant; Epider | 1986 |
[Hereditary bullous epidermolysis].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Child, Preschool; Epidermolysis Bullosa; Female; | 1985 |
Hereditary epidermolysis bullosa.
Topics: Adult; Animals; Child; Child, Preschool; Chloroquine; Dogs; Epidermolysis Bullosa; Female; Humans; I | 1985 |
1 trial available for phenytoin and Acantholysis Bullosa
| Article | Year |
|---|---|
Phenytoin therapy of recessive dystrophic epidermolysis bullosa. Clinical trial and proposed mechanism of action on collagenase.
Topics: Administration, Oral; Adolescent; Blister; Child; Child, Preschool; Clinical Trials as Topic; Cultur | 1980 |
30 other studies available for phenytoin and Acantholysis Bullosa
| Article | Year |
|---|---|
Phenytoin therapy in a neonate diagnosed with epidermolysis bullosa.
Topics: Dermatologic Agents; Epidermolysis Bullosa; Female; Humans; Infant, Newborn; Phenytoin; Voltage-Gate | 2013 |
What's new in pediatric dermatology.
Topics: Anti-Bacterial Agents; Aspirin; Epidermolysis Bullosa; Hexachlorocyclohexane; Humans; Impetigo; Infa | 1981 |
Therapeutic considerations in recessive dystrophic epidermolysis bullosa.
Topics: Cells, Cultured; Dose-Response Relationship, Drug; Epidermolysis Bullosa; Genes, Recessive; Glucocor | 1981 |
Collagen metabolism in two rare forms of epidermolysis bullosa.
Topics: Adolescent; Adult; Cell Line; Collagen; Epidermolysis Bullosa; Female; Humans; Male; Microbial Colla | 1984 |
Epidermolysis bullosa in Finland. Clinical features, morphology and relation to collagen metabolism.
Topics: Adolescent; Adult; Child; Child, Preschool; Collagen; Epidermolysis Bullosa; Female; Fibroblasts; Fi | 1984 |
Management of esophageal stenosis in recessive dystrophic epidermolysis bullosa.
Topics: Adolescent; Adult; Child; Child, Preschool; Combined Modality Therapy; Dilatation; Enteral Nutrition | 1984 |
[Phenytoin in recessive dystrophic epidermolysis bullosa].
Topics: Epidermolysis Bullosa; Humans; Infant; Infant, Newborn; Phenytoin | 1984 |
Junctional epidermolysis bullosa. Treatment with phenytoin.
Topics: Diagnosis, Differential; Epidermolysis Bullosa; Humans; Infant; Male; Microscopy, Electron; Phenytoi | 1983 |
Phenytoin therapy for junctional epidermolysis bullosa.
Topics: Adolescent; Epidermolysis Bullosa; Female; Humans; Infant; Infant, Newborn; Phenytoin; Pregnancy | 1983 |
Therapeutic efficacy of phenytoin in recessive dystrophic epidermolysis. A comparison of short- and long-term treatment.
Topics: Adolescent; Adult; Blister; Child; Child, Preschool; Epidermolysis Bullosa; Female; Humans; Infant; | 1984 |
[Phenytoin therapy in recessive dystrophic epidermolyses (epidermolysis bullosa dystrophica type Hallopeau-Siemens and epidermolysis bullosa dystrophica inversa)].
Topics: Administration, Oral; Adolescent; Child, Preschool; Consanguinity; Epidermolysis Bullosa; Female; Ge | 1983 |
Sixteen types of epidermolysis bullosa. On the clinical discrimination, therapy and prenatal diagnosis.
Topics: Adrenal Cortex Hormones; Adult; Blister; Child, Preschool; Epidermolysis Bullosa; Female; Hot Temper | 1981 |
Epidermolysis bullosa letalis and phenytoin.
Topics: Epidermolysis Bullosa; Humans; Immunocompetence; Infant; Male; Phagocytosis; Phenytoin | 1982 |
[The effectiveness of phenytoin in the treatment of epidermolysis bullosa hereditaria dystrophica partim inversa (Gedde-Dahl)].
Topics: Adult; Biopsy; Epidermolysis Bullosa; Humans; Male; Microscopy, Electron; Pedigree; Phenytoin; Skin; | 1982 |
Nonlinear kinetics of phenytoin in children.
Topics: Adolescent; Adult; Age Factors; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, | 1982 |
Epidermolysis bullosa in the eastern province of Saudi Arabia.
Topics: Adult; Child, Preschool; Epidermolysis Bullosa; Female; Humans; Infant; Infant, Newborn; Male; Pheny | 1993 |
Epidermolysis bullosa--new therapeutic approaches.
Topics: Adolescent; Adult; Child, Preschool; Epidermolysis Bullosa; Female; Humans; In Vitro Techniques; Inf | 1978 |
[Dilatation treatment of esophageal stenoses in young patients with recessive epidermolysis bullosa dystrophica].
Topics: Adolescent; Adult; Catheterization; Combined Modality Therapy; Epidermolysis Bullosa; Esophageal Ste | 1990 |
Management of oesophageal stenosis in epidermolysis bullosa dystrophica.
Topics: Adolescent; Adrenal Cortex Hormones; Child; Child, Preschool; Deglutition Disorders; Dilatation; Epi | 1989 |
A perspective on the role of collagenase in recessive dystrophic epidermolysis bullosa.
Topics: Epidermolysis Bullosa; Fibroblasts; Humans; Microbial Collagenase; Phenytoin | 1988 |
[Hereditary bullous epidermolyses. Recent aspects of diagnosis and therapy].
Topics: Antibodies, Monoclonal; Antibody Specificity; Autoantigens; Basement Membrane; Carrier Proteins; Chr | 1986 |
Death from metastatic, cutaneous, squamous cell carcinoma in autosomal recessive dystrophic epidermolysis bullosa despite permanent inpatient care.
Topics: Adult; Anti-Bacterial Agents; Carcinoma, Squamous Cell; Epidermolysis Bullosa; Fatty Acids; Female; | 1988 |
Genetic principles applied to skin disease.
Topics: Drug Resistance; Epidermolysis Bullosa; Genes, Dominant; Genetic Techniques; Genetic Variation; Huma | 1987 |
Dermolytic (dystrophic) epidermolysis bullosa inversa.
Topics: Adult; Blister; Conjunctivitis; Epidermolysis Bullosa; Esophageal Stenosis; Female; Humans; Keratiti | 1988 |
Efficacy of systemic phenytoin in the treatment of junctional epidermolysis bullosa.
Topics: Administration, Oral; Adolescent; Child; Epidermolysis Bullosa; Humans; Phenytoin | 1988 |
Abnormalities of plasma and erythrocyte essential fatty acid composition in epidermolysis bullosa: influence of treatment with diphenylhydantoin.
Topics: Adult; Child; Cholesterol; Copper; Epidermolysis Bullosa; Erythrocytes; Fatty Acids, Essential; Huma | 1987 |
Phenytoin treatment of RDEB vegetans.
Topics: Adult; Epidermolysis Bullosa; Humans; Male; Phenytoin | 1986 |
Phenytoin and junctional epidermolysis bullosa.
Topics: Epidermolysis Bullosa; Humans; Infant; Phenytoin | 1985 |
Dystrophic epidermolysis bullosa treated unsuccessfully with oral zinc.
Topics: Acrodermatitis; Administration, Oral; Adolescent; Child, Preschool; Epidermolysis Bullosa; Female; H | 1985 |
[Therapy of esophageal stenoses in recessive epidermolysis bullosa dystrophica].
Topics: Child; Combined Modality Therapy; Dilatation; Epidermolysis Bullosa; Esophageal Stenosis; Female; Ge | 1985 |