phenytoin has been researched along with Abnormalities, Congenital in 18 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " Of the study group, 106 children had been exposed to antiepileptic drugs (82 to phenytoin) during pregnancy; 44 (36%) mothers had had generalized convulsions during pregnancy." | 3.67 | Minor anomalies in offspring of epileptic mothers. ( Bardy, A; Gaily, E; Granström, ML; Hiilesmaa, V, 1988) |
| " Administering phenytoin in the drinking water of females homozygous for the quaking allele reduced the frequency of tonic-clonic seizures typical for this mutant from a background rate of 2." | 3.66 | Mouse fetal hydantoin syndrome: effects of maternal seizures. ( Chernoff, GF; Finnell, RH, 1982) |
| ", raise the possibility that fetal damage previously attributed to phenytoin and other anticonvulsant drugs, principally phenobarbitone, may be due to epilepsy itself." | 3.65 | Anticonvulsants and parental epilepsy in the development of birth defects. ( Hartz, SC; Heinonen, OP; Mitchell, AA; Monson, RR; Rosenberg, L; Shapiro, S; Siskind, V; Slone, D, 1976) |
| "Seizures and intracranial hemorrhage are possible medical diseases that any obstetrician may encounter." | 2.49 | Seizures and intracranial hemorrhage. ( Alexander, JM; Wilson, KL, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (77.78) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wilson, KL | 1 |
| Alexander, JM | 1 |
| Hiilesmaa, VK | 1 |
| Teramo, K | 1 |
| Granström, ML | 2 |
| Bardy, AH | 1 |
| Finnell, RH | 1 |
| Chernoff, GF | 1 |
| Canger, R | 1 |
| Battino, D | 1 |
| Canevini, MP | 1 |
| Fumarola, C | 1 |
| Guidolin, L | 1 |
| Vignoli, A | 1 |
| Mamoli, D | 1 |
| Palmieri, C | 1 |
| Molteni, F | 1 |
| Granata, T | 1 |
| Hassibi, P | 1 |
| Zamperini, P | 1 |
| Pardi, G | 1 |
| Avanzini, G | 1 |
| Holmes, LB | 2 |
| Harvey, EA | 1 |
| Coull, BA | 1 |
| Huntington, KB | 1 |
| Khoshbin, S | 1 |
| Hayes, AM | 1 |
| Ryan, LM | 1 |
| Shapiro, S | 2 |
| Hartz, SC | 2 |
| Siskind, V | 1 |
| Mitchell, AA | 1 |
| Slone, D | 2 |
| Rosenberg, L | 2 |
| Monson, RR | 2 |
| Heinonen, OP | 2 |
| Shepard, TH | 1 |
| Janz, D | 1 |
| Annegers, JF | 2 |
| Hauser, WA | 2 |
| Elveback, LR | 2 |
| Anderson, VE | 1 |
| Kurland, LI | 1 |
| Durner, M | 1 |
| Greenberg, DA | 1 |
| Delgado-Escueta, AV | 1 |
| Gaily, E | 1 |
| Hiilesmaa, V | 1 |
| Bardy, A | 1 |
| Kleiner, BC | 1 |
| Leppig, KA | 1 |
| Cann, CI | 1 |
| Muñoz, A | 1 |
| Polk, BF | 1 |
| McClain, RM | 1 |
| Rohrs, JM | 1 |
| Lowe, CR | 1 |
| Kurland, LT | 1 |
| Fedrick, J | 1 |
| Hill, RM | 1 |
2 reviews available for phenytoin and Abnormalities, Congenital
| Article | Year |
|---|---|
Seizures and intracranial hemorrhage.
Topics: Anticonvulsants; Carbamazepine; Congenital Abnormalities; Eclampsia; Epilepsy; Female; Folic Acid; H | 2013 |
Is there a genetic relationship between epilepsy and birth defects?
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Cleft Lip; Cleft Palate; Congenital Abnormalities; Dis | 1992 |
16 other studies available for phenytoin and Abnormalities, Congenital
| Article | Year |
|---|---|
Serum folate concentrations during pregnancy in women with epilepsy: relation to antiepileptic drug concentrations, number of seizures, and fetal outcome.
Topics: Carbamazepine; Congenital Abnormalities; Epilepsy; Female; Fetal Death; Folic Acid; Humans; Phenobar | 1983 |
Mouse fetal hydantoin syndrome: effects of maternal seizures.
Topics: Abnormalities, Drug-Induced; Animals; Congenital Abnormalities; Female; Maternal-Fetal Exchange; Mic | 1982 |
Malformations in offspring of women with epilepsy: a prospective study.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Comorbidity; Congenital Abnormalities; | 1999 |
The teratogenicity of anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Case-Control Studies; Congenital Abnorm | 2001 |
Anticonvulsants and parental epilepsy in the development of birth defects.
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Epilepsy; Female; Finland; Follow-Up Studies; | 1976 |
Teratogenicity of therapeutic agents.
Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Abortion, Induced; Anesthetics; Anima | 1979 |
[Do antiepileptics have a teratogenic effect?].
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Congenital Abnormalities; Epilepsy; Female; Humans; In | 1978 |
Congenital malformations and seizure disorders in the offspring of parents with epilepsy.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Barbiturates; Child; Child, Preschool; Congenital Ab | 1978 |
Minor anomalies in offspring of epileptic mothers.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Child; Child, Preschool; Congenital Abnormalities; E | 1988 |
Predictive value of minor anomalies: II. Use in cohort studies to identify teratogens.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Congenital Abnormalities; Diabetes Mellitus, Type 1; F | 1987 |
Potentiation of the teratogenic effects and altered disposition of diphenylhydantoin in mice fed a purified diet.
Topics: Analysis of Variance; Animals; Cleft Palate; Congenital Abnormalities; Diet; Female; Fetus; Hexobarb | 1985 |
Congenital malformations among infants born to epileptic women.
Topics: Abnormalities, Drug-Induced; Cleft Lip; Cleft Palate; Congenital Abnormalities; England; Epilepsy; F | 1973 |
Do anticonvulsants have a teratogenic effect?
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Child, Preschool; Cleft Lip; Cleft Palate; Congenital | 1974 |
Epilepsy and pregnancy: a report from the Oxford Record Linkage Study.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Age Factors; Child; Congenital Abnormalities; Drug S | 1973 |
Diphenylhydantoin and selected congenital malformations.
Topics: Abnormalities, Drug-Induced; Adult; Birth Weight; Congenital Abnormalities; Epilepsy; Female; Fetus; | 1973 |
Editorial: Teratogenesis and antiepileptic drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Cleft Lip; Cleft Palate; Congenital Abnormalities; Epi | 1973 |