phenylthiourea and Drug-Hypersensitivity

phenylthiourea has been researched along with Drug-Hypersensitivity* in 4 studies

Reviews

2 review(s) available for phenylthiourea and Drug-Hypersensitivity

Article	Year
Advances in pharmacogenetics. Progress in medical genetics, 1973, Volume: 9 Topics: Alcohol Oxidoreductases; Catalase; Cholinesterases; Dicumarol; Diseases in Twins; Drug Hypersensitivity; Drug Resistance; Drug-Related Side Effects and Adverse Reactions; Environment; Female; Genetic Diseases, Inborn; Glaucoma; Glucosephosphate Dehydrogenase Deficiency; Hemoglobins; Humans; Infant, Newborn; Intraocular Pressure; Isoniazid; Malignant Hyperthermia; Mutation; Pharmaceutical Preparations; Pharmacogenetics; Phenylthiourea; Phenytoin; Pregnancy; Protein Binding; Racial Groups; Warfarin	1973
Recent progress in pharmacogenetics. Advances in pharmacology, 1969, Volume: 7 Topics: Adult; Aged; Alcohol Oxidoreductases; Antipyrine; Asian People; Child, Preschool; Cholinesterases; Cyanides; Dicumarol; Diseases in Twins; Drug Hypersensitivity; Erythrocytes; Favism; Female; Glucosephosphate Dehydrogenase Deficiency; Hemoglobins; Humans; Isoniazid; Liver; Male; Metabolism, Inborn Errors; Middle Aged; Pharmacogenetics; Phenylbutazone; Phenylthiourea; Phenytoin; Pregnancy; Primaquine; Twins; Warfarin	1969

Article

Year

Progress in medical genetics, 1973, Volume: 9

Topics: Alcohol Oxidoreductases; Catalase; Cholinesterases; Dicumarol; Diseases in Twins; Drug Hypersensitivity; Drug Resistance; Drug-Related Side Effects and Adverse Reactions; Environment; Female; Genetic Diseases, Inborn; Glaucoma; Glucosephosphate Dehydrogenase Deficiency; Hemoglobins; Humans; Infant, Newborn; Intraocular Pressure; Isoniazid; Malignant Hyperthermia; Mutation; Pharmaceutical Preparations; Pharmacogenetics; Phenylthiourea; Phenytoin; Pregnancy; Protein Binding; Racial Groups; Warfarin

1973

Recent progress in pharmacogenetics.

Advances in pharmacology, 1969, Volume: 7

Topics: Adult; Aged; Alcohol Oxidoreductases; Antipyrine; Asian People; Child, Preschool; Cholinesterases; Cyanides; Dicumarol; Diseases in Twins; Drug Hypersensitivity; Erythrocytes; Favism; Female; Glucosephosphate Dehydrogenase Deficiency; Hemoglobins; Humans; Isoniazid; Liver; Male; Metabolism, Inborn Errors; Middle Aged; Pharmacogenetics; Phenylbutazone; Phenylthiourea; Phenytoin; Pregnancy; Primaquine; Twins; Warfarin

1969

Trials

1 trial(s) available for phenylthiourea and Drug-Hypersensitivity

Article	Year
[Rifampicin in the treatment of active pulmonary tuberculosis. Controlled trial of isoniazid-rifampicin-thiocarlide versus isoniazid-streptomycin-thiocarlide in untreated tuberculosis. Treatment of relapses with the combination rifampicin-ethambutol-thioc Schweizerische medizinische Wochenschrift, 1974, Mar-09, Volume: 104, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Drug Hypersensitivity; Drug Therapy, Combination; Ethambutol; Gastrointestinal Diseases; Humans; Isoniazid; Mycobacterium tuberculosis; Phenylthiourea; Pyridoxine; Recurrence; Rifampin; Streptomycin; Thrombocytopenia; Time Factors; Tuberculosis, Pulmonary	1974

Article

Year

[Rifampicin in the treatment of active pulmonary tuberculosis. Controlled trial of isoniazid-rifampicin-thiocarlide versus isoniazid-streptomycin-thiocarlide in untreated tuberculosis. Treatment of relapses with the combination rifampicin-ethambutol-thioc

Schweizerische medizinische Wochenschrift, 1974, Mar-09, Volume: 104, Issue:10

Topics: Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Drug Hypersensitivity; Drug Therapy, Combination; Ethambutol; Gastrointestinal Diseases; Humans; Isoniazid; Mycobacterium tuberculosis; Phenylthiourea; Pyridoxine; Recurrence; Rifampin; Streptomycin; Thrombocytopenia; Time Factors; Tuberculosis, Pulmonary

1974

Other Studies

1 other study(ies) available for phenylthiourea and Drug-Hypersensitivity

Article	Year
PTC-tasting ability in populations living in Kirghizia with special reference to hypersensitivity: its relation to sex and age. Human genetics, 1979, Jan-19, Volume: 46, Issue:1 The dimorphism in sensitivity to PTC, with a dilution scale up to 29, was studied in 320 male and 320 female Kirghiz students, 45 male and 200 female Russian students in Frunze, and in 734 Kirghiz schoolchildren in a high-altitude area of South Kirghizia. Gene t frequency was 0.44 for the Kirghiz students, 0.56 for the Russian students, and 0.54 for the Kirghiz schoolchildren. In all the groups studied it was established that such factors as sex and age have no modifying effect on sensitivity to PTC and the pattern of the distribution of sensitivity. In all the groups the frequency of 'tasters' exceeded that of 'nontasters.' Among the Kirghiz students there was a very small percentage (1.2%) of hypersensitive subjects (dil. No. 18), while 14.1% of the Kirghiz children of one Kyzyl-Dzhar school were hypersensitive. Genealogical studies showed that all the hypersensitive subjects belonged to one small stock and lived in the same village. Family studies of probands suggest the existence of a new (third) allele (T2) which determines hypersensitivity to PTC. Topics: Adolescent; Age Factors; Child; Drug Hypersensitivity; Female; Gene Frequency; Genes, Recessive; Genetics, Medical; Humans; Male; Phenylthiourea; Sex Factors; Taste; USSR	1979

Article

Year

PTC-tasting ability in populations living in Kirghizia with special reference to hypersensitivity: its relation to sex and age.

Human genetics, 1979, Jan-19, Volume: 46, Issue:1

The dimorphism in sensitivity to PTC, with a dilution scale up to 29, was studied in 320 male and 320 female Kirghiz students, 45 male and 200 female Russian students in Frunze, and in 734 Kirghiz schoolchildren in a high-altitude area of South Kirghizia. Gene t frequency was 0.44 for the Kirghiz students, 0.56 for the Russian students, and 0.54 for the Kirghiz schoolchildren. In all the groups studied it was established that such factors as sex and age have no modifying effect on sensitivity to PTC and the pattern of the distribution of sensitivity. In all the groups the frequency of 'tasters' exceeded that of 'nontasters.' Among the Kirghiz students there was a very small percentage (1.2%) of hypersensitive subjects (dil. No. 18), while 14.1% of the Kirghiz children of one Kyzyl-Dzhar school were hypersensitive. Genealogical studies showed that all the hypersensitive subjects belonged to one small stock and lived in the same village. Family studies of probands suggest the existence of a new (third) allele (T2) which determines hypersensitivity to PTC.

Topics: Adolescent; Age Factors; Child; Drug Hypersensitivity; Female; Gene Frequency; Genes, Recessive; Genetics, Medical; Humans; Male; Phenylthiourea; Sex Factors; Taste; USSR

1979