phenylthiourea and Diabetes-Mellitus

Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Clinical Trials as Topic; Dexamethasone; Diabetes Complications; Diabetes Mellitus; Glaucoma; Humans; Hydrocortisone; Intraocular Pressure; Phenotype; Phenylthiourea; Pituitary-Adrenal Function Tests; Taste; Thyroid Function Tests

Effect of high blood glucose levels in diabetes mellitus was studied on gustatory responses to glucose in PTC tasters and non-tasters, before and after the ingestion of a glucose solution. After a 12-h overnight fast, prescreening for phenylthiocarbamide (PTC) sensitivity was done in each subject, and then each subject tasted, and rated, 7 concentrations of glucose solutions for intensity and hedonic responses. Blood glucose levels were also determined under fasting and then after a 100-g glucose load. A decrease in palatability of the glucose solutions induced by the glucose load (negative alliaesthesia) was evident in both groups of subjects. Tasters showed higher hedonic ratings (Mean 4-25), as compared to non-tasters (Mean 3-70) and this difference was more evident after the glucose load in non-tasters.

Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus; Fasting; Glucose; Humans; Phenylthiourea; Taste; Taste Disorders; Time Factors

Topics: Adolescent; Adult; Aged; Diabetes Mellitus; Female; Humans; Male; Middle Aged; Phenylthiourea; Taste

Topics: Adolescent; Adult; Aged; Child; Diabetes Mellitus; Ethnicity; Female; Humans; Male; Middle Aged; Phenylthiourea; Taste

Topics: Biomedical Research; Diabetes Mellitus; Diagnosis; Humans; Phenylthiourea; Taste; Thiourea

Topics: Adolescent; Child; Diabetes Mellitus; Geriatrics; Italy; Neoplasms; Phenylthiourea; Research; Taste; Thiourea; Tuberculosis

Topics: Diabetes Mellitus; Goiter; Humans; Phenylthiourea; Taste; Thiourea