phenylpyruvic acid has been researched along with Disease Models, Animal in 3 studies
phenylpyruvic acid: RN given refers to parent cpd
phenylpyruvate : A 2-oxo monocarboxylic acid anion resulting from deprotonation of the carboxy group of either keto- or enol-phenylpyruvic acid.
keto-phenylpyruvic acid : A 2-oxo monocarboxylic acid that is 3-phenylpropanoic acid substituted by an oxo group at position 2. It is an intermediate metabolite in the phenylalanine pathway.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenylketonuria is an autosomal recessive disorder caused by a deficiency of phenylalanine hydroxylase." | 1.36 | Tissue-specific activation of mitogen-activated protein kinases for expression of transthyretin by phenylalanine and its metabolite, phenylpyruvic acid. ( Choi, JO; Jung, SC; Lee, MH; Park, HY; Park, JW, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Park, JW | 1 |
| Lee, MH | 1 |
| Choi, JO | 1 |
| Park, HY | 1 |
| Jung, SC | 1 |
| Gazit, V | 1 |
| Ben-Abraham, R | 1 |
| Rudin, M | 1 |
| Katz, Y | 1 |
| Sarkissian, CN | 1 |
| Scriver, CR | 1 |
| Mamer, OA | 1 |
3 other studies available for phenylpyruvic acid and Disease Models, Animal
| Article | Year |
|---|---|
Tissue-specific activation of mitogen-activated protein kinases for expression of transthyretin by phenylalanine and its metabolite, phenylpyruvic acid.
Topics: Animals; Brain Stem; Disease Models, Animal; Gene Expression Regulation; Hep G2 Cells; Hepatocyte Nu | 2010 |
Glucose-lowering effect of beta-phenylpyruvate in neonatal mice: a possible mechanism for phenylketonuria-related neurodegenerative changes.
Topics: Animals; Animals, Newborn; Blood Glucose; Brain; Disease Models, Animal; Dose-Response Relationship, | 2003 |
Measurement of phenyllactate, phenylacetate, and phenylpyruvate by negative ion chemical ionization-gas chromatography/mass spectrometry in brain of mouse genetic models of phenylketonuria and non-phenylketonuria hyperphenylalaninemia.
Topics: Animals; Brain; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Humans; Lactates; Mice | 2000 |