phenylpyruvic acid has been researched along with BH4 Deficiency in 55 studies
phenylpyruvic acid: RN given refers to parent cpd
phenylpyruvate : A 2-oxo monocarboxylic acid anion resulting from deprotonation of the carboxy group of either keto- or enol-phenylpyruvic acid.
keto-phenylpyruvic acid : A 2-oxo monocarboxylic acid that is 3-phenylpropanoic acid substituted by an oxo group at position 2. It is an intermediate metabolite in the phenylalanine pathway.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Protein substitutes developed for phenylketonuria (PKU) are a synthetic source of protein commonly based on L-amino acids." | 2.72 | Protein Substitutes in PKU; Their Historical Evolution. ( Ashmore, C; Daly, A; Evans, S; MacDonald, A; Pinto, A, 2021) |
| "The inborn error of metabolism phenylketonuria (PKU, OMIM 261600) is most often due to inactivation of phenylalanine hydroxylase (PAH), which converts phenylalanine (Phe) into tyrosine (Tyr)." | 1.91 | Competitive, multi-objective, and compartmented Flux Balance Analysis for addressing tissue-specific inborn errors of metabolism. ( Liu, Y; Westerhoff, HV, 2023) |
| "Phenylketonuria is an autosomal recessive disorder caused by a deficiency of phenylalanine hydroxylase." | 1.36 | Tissue-specific activation of mitogen-activated protein kinases for expression of transthyretin by phenylalanine and its metabolite, phenylpyruvic acid. ( Choi, JO; Jung, SC; Lee, MH; Park, HY; Park, JW, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 40 (72.73) | 18.7374 |
| 1990's | 5 (9.09) | 18.2507 |
| 2000's | 5 (9.09) | 29.6817 |
| 2010's | 3 (5.45) | 24.3611 |
| 2020's | 2 (3.64) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, Y | 1 |
| Westerhoff, HV | 1 |
| Daly, A | 1 |
| Evans, S | 1 |
| Pinto, A | 1 |
| Ashmore, C | 1 |
| MacDonald, A | 1 |
| Sanayama, Y | 1 |
| Matsumoto, A | 1 |
| Shimojo, N | 1 |
| Kohno, Y | 1 |
| Nakaya, H | 1 |
| MUNRO, TA | 1 |
| Park, JW | 1 |
| Lee, MH | 1 |
| Choi, JO | 1 |
| Park, HY | 1 |
| Jung, SC | 1 |
| PENROSE, LS | 2 |
| Zhang, D | 1 |
| Li, W | 1 |
| Zhang, J | 1 |
| Tang, W | 1 |
| Qian, C | 1 |
| Feng, M | 1 |
| Chu, Q | 1 |
| Ye, J | 1 |
| Gazit, V | 1 |
| Ben-Abraham, R | 1 |
| Rudin, M | 1 |
| Katz, Y | 1 |
| Christ, SE | 1 |
| JERVIS, GA | 1 |
| ARMSTRONG, MD | 2 |
| LOW, NL | 2 |
| KNOX, WE | 2 |
| HSIA, DY | 1 |
| THE, TP | 1 |
| FLEURY, P | 1 |
| VINK, CL | 2 |
| JONXIS, JH | 1 |
| STRODER, J | 1 |
| GEISLER, E | 1 |
| VIZET, J | 1 |
| SMITH, AJ | 1 |
| STRANG, LB | 1 |
| ASPERGER, H | 1 |
| FOLLING, A | 1 |
| SYDNES, S | 2 |
| TASHIAN, RE | 1 |
| WOOLF, LI | 1 |
| BISAZ, S | 1 |
| FARQUHAR, JW | 2 |
| KANSAS, ET | 1 |
| TAIT, HP | 2 |
| HABERLANDT, WF | 1 |
| HUMBEL, R | 1 |
| SCHATZ, F | 1 |
| RICHMOND, J | 1 |
| CHRISTIAENS, L | 1 |
| GAUDIER, B | 1 |
| BRIET, B | 1 |
| KRUPANIDHI, I | 1 |
| PUNEKAR, BD | 1 |
| GOSWAMI, ND | 1 |
| LYNCH, RD | 1 |
| DAVID, JM | 1 |
| HASSAN, MM | 1 |
| ALLEN, RJ | 1 |
| WILSON, JL | 1 |
| WOOLLEY, DW | 1 |
| VANDERHOEVEN, T | 1 |
| WHITEHEAD, RG | 1 |
| MILBURN, TR | 1 |
| ALLEGRANZA, A | 1 |
| ALDEGHI, E | 1 |
| CANEVINI, P | 1 |
| DEVITO, C | 1 |
| WU, WY | 1 |
| SVENNEBY, G | 1 |
| KVAMME, E | 1 |
| EITINGER, L | 1 |
| RUPE, CO | 1 |
| FREE, AH | 1 |
| COWIE, VA | 1 |
| Langenbeck, U | 2 |
| Behbehani, A | 2 |
| Luthe, H | 1 |
| Dorland, L | 1 |
| Poll-The, BT | 1 |
| Duran, M | 1 |
| Smeitink, JA | 1 |
| Berger, R | 1 |
| Vilaseca, MA | 1 |
| Farré, C | 1 |
| Ramón, F | 1 |
| Sarkissian, CN | 1 |
| Scriver, CR | 1 |
| Mamer, OA | 1 |
| Fischer, GM | 1 |
| Nemeti, B | 1 |
| Farkas, V | 1 |
| Debreceni, B | 1 |
| Laszlo, A | 1 |
| Schaffer, Z | 1 |
| Somogyi, C | 1 |
| Sandor, A | 1 |
| Berti, SL | 1 |
| Bonan, CD | 1 |
| da Silva, FL | 1 |
| Battastini, AM | 1 |
| Sarkis, JJ | 1 |
| Wannmacher, CM | 1 |
| Mench-Hoinowski, A | 1 |
| Kishida, M | 1 |
| Makita, Y | 1 |
| Suzuki, T | 1 |
| Yamada, M | 1 |
| Hobo, T | 1 |
| Mönch, E | 1 |
| Kneer, J | 1 |
| Jakobs, C | 1 |
| Arnold, M | 1 |
| Diehl, H | 1 |
| Batzler, U | 1 |
| Antoshechkin, AG | 1 |
| Zuyeva, LA | 1 |
| Maximova, LA | 1 |
| Hsiao, KJ | 1 |
| Hung, SH | 1 |
| Wu, SJ | 1 |
| Yeh, SF | 1 |
| Michals, K | 1 |
| Matalon, R | 1 |
2 reviews available for phenylpyruvic acid and BH4 Deficiency
| Article | Year |
|---|---|
Protein Substitutes in PKU; Their Historical Evolution.
Topics: Amino Acids; Animals; Caseins; Child, Preschool; Dietary Proteins; Female; History, 20th Century; Hi | 2021 |
PHENYLKETONURIA IN PEDIATRIC PRACTICE.
Topics: Child; Diet; Diet Therapy; Humans; Intelligence; Phenylalanine; Phenylketonurias; Phenylpyruvic Acid | 1963 |
53 other studies available for phenylpyruvic acid and BH4 Deficiency
| Article | Year |
|---|---|
Competitive, multi-objective, and compartmented Flux Balance Analysis for addressing tissue-specific inborn errors of metabolism.
Topics: Humans; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Phenylpyruvic Acids; Tyrosine | 2023 |
Phenylalanine sensitive K562-D cells for the analysis of the biochemical impact of excess amino acid.
Topics: Adaptor Proteins, Signal Transducing; Biological Transport; Cell Differentiation; Cell Proliferation | 2014 |
Phenylketonuria; data on 47 British families.
Topics: Ethnicity; Humans; Phenylketonurias; Phenylpyruvic Acids; Urine | 1947 |
Tissue-specific activation of mitogen-activated protein kinases for expression of transthyretin by phenylalanine and its metabolite, phenylpyruvic acid.
Topics: Animals; Brain Stem; Disease Models, Animal; Gene Expression Regulation; Hep G2 Cells; Hepatocyte Nu | 2010 |
Asearch for linkage between the A,B,C agglutinogens and phenylketonuria.
Topics: Antigens; Blood Group Antigens; Body Fluids; Genetic Linkage; Humans; Phenylketonurias; Phenylpyruvi | 1945 |
Study on urinary metabolic profile of phenylketonuria by micellar electrokinetic capillary chromatography with dual electrochemical detection--potential clinical application in fast diagnosis of phenylketonuria.
Topics: Chromatography, Micellar Electrokinetic Capillary; Electrochemical Techniques; Humans; Hydrogen-Ion | 2011 |
Glucose-lowering effect of beta-phenylpyruvate in neonatal mice: a possible mechanism for phenylketonuria-related neurodegenerative changes.
Topics: Animals; Animals, Newborn; Blood Glucose; Brain; Disease Models, Animal; Dose-Response Relationship, | 2003 |
Asbjørn Følling and the discovery of phenylketonuria.
Topics: Female; History, 19th Century; History, 20th Century; Humans; Male; Norway; Phenylketonurias; Phenyl | 2003 |
Studies on phenylpyruvic oligophrenia; phenylpyruvic acid content on blood.
Topics: Blood; Humans; Intellectual Disability; Phenylketonurias; Phenylpyruvic Acids | 1952 |
Phenylketonuria VIII. Relation between age, serum phenylalanine level, and phenylpyruvic acid excretion.
Topics: Biochemical Phenomena; Biological Transport; Body Fluids; Humans; Phenylalanine; Phenylketonurias; P | 1957 |
Phenylketonuria VIII. Relation between age, serum phenylalanine level, and phenylpyruvic acid excretion.
Topics: Biochemical Phenomena; Biological Transport; Body Fluids; Humans; Phenylalanine; Phenylketonurias; P | 1957 |
Phenylketonuria VIII. Relation between age, serum phenylalanine level, and phenylpyruvic acid excretion.
Topics: Biochemical Phenomena; Biological Transport; Body Fluids; Humans; Phenylalanine; Phenylketonurias; P | 1957 |
Phenylketonuria VIII. Relation between age, serum phenylalanine level, and phenylpyruvic acid excretion.
Topics: Biochemical Phenomena; Biological Transport; Body Fluids; Humans; Phenylalanine; Phenylketonurias; P | 1957 |
Pathogenetic problems in phenylketonuria.
Topics: Phenylketonurias; Phenylpyruvic Acids | 1957 |
Determination of phenylpyruvic acid in the urine of patients with oligophrenia phenylpyruvica.
Topics: Body Fluids; Humans; Phenylketonurias; Phenylpyruvic Acids | 1957 |
Excretion of phenylalanine; report of two cases of phenyl pyruvic acid oligophrenia.
Topics: Biological Transport; Humans; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Pyruvic Acid | 1957 |
[Influence of fructose on phenylpyruvic acid excretion in phenylpyruvic oligophrenia].
Topics: Biological Transport; Body Fluids; Fructose; Leadership; Phenylketonurias; Phenylpyruvic Acids | 1957 |
[Infra-red spectroscopy of phenylpyruvic acid in urine of phenylketonuric patients].
Topics: Body Fluids; Humans; Phenylketonurias; Phenylpyruvic Acids; Spectrum Analysis | 1958 |
An inborn error of metabolism with the urinary excretion of alpha-hydroxy-butyric acid and phenylpyruvic acid.
Topics: Butyrates; Humans; Ketone Bodies; Phenylketonurias; Phenylpyruvic Acids | 1958 |
[Phenylpyruvic acid oligophrenia].
Topics: Medical Records; Phenylketonurias; Phenylpyruvic Acids | 1958 |
A method for the estimation of phenylpyruvic acid in urine with some examples of its use in dietary treatment of phenylpyruvic oligophrenia.
Topics: Diet; Humans; Phenylketonurias; Phenylpyruvic Acids; Regression Analysis | 1958 |
Phenylpyruvic acid as a possible precursor of o-hydroxyphenylacetic acid in man.
Topics: Administration, Oral; Humans; Male; Phenylacetates; Phenylalanine; Phenylketonurias; Phenylpyruvic A | 1959 |
Tests for phenylketonuria.
Topics: Body Fluids; Humans; Phenylketonurias; Phenylpyruvic Acids | 1961 |
[Determination of phenylalanine and phenylpyruvic acid in the blood and urine. Application to two cases of phenylpyruvic oligophrenia].
Topics: Body Fluids; Humans; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids | 1959 |
[Phenylpyruvic oligophrenia. Detection and semiquantitative determination of phenylpyruvic acid in the urine with the help of phenistix].
Topics: Body Fluids; Humans; Phenylketonurias; Phenylpyruvic Acids | 1960 |
Problems of routine screening for phenylketonuria.
Topics: Humans; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids | 1962 |
The renal clearance of phenylpyruvate.
Topics: Humans; Kidney; Phenylketonurias; Phenylpyruvic Acids | 1961 |
[Clinico-genetic studies in phenylpyruvic acid feeblemindedness].
Topics: Chromosomes; Phenylketonurias; Phenylpyruvic Acids; Research | 1963 |
[Identification and determination of phenylpyruvic acid in the urine].
Topics: Body Fluids; Humans; Phenylketonurias; Phenylpyruvic Acids | 1963 |
[Contribution to determination of alpha-keto acids in the urine, with special reference to phenylpyruvic acid].
Topics: Humans; Keto Acids; Phenylketonurias; Phenylpyruvic Acids | 1962 |
[PHENYLKETONURIA. APROPOS OF A FAMILIAL CASE].
Topics: Blood Chemical Analysis; Body Fluids; Diet; Diet Therapy; Electroencephalography; Genetics, Medical; | 1963 |
A STUDY OF THE INCIDENCE OF PHENYLKETONURIA IN INDIA.
Topics: Blood; Consanguinity; Epidemiology; Family; Humans; Incidence; India; Infant; Infant, Newborn; Pheny | 1963 |
THE INDUCTION OF TYROSYLURIA IN YOUNG RATS.
Topics: Animals; Ascorbic Acid; Guinea Pigs; Metabolism; Phenylketonurias; Phenylpyruvic Acids; Rats; Resear | 1963 |
[RECENT KNOWLEDGE ABOUT THE PROBLEM OF PHENYLPYRUVIC OLIGOPHRENIA. FREQUENCY, GENETICS, BIOCHEMISTRY, DIAGNOSIS, AND THERAPEUTICS].
Topics: Asparagine; Biochemistry; Diet; Diet Therapy; Genetics, Medical; Glutamine; Humans; Knowledge; Niala | 1963 |
PHENYLKETONURIA IN A SUDANESE FAMILY.
Topics: Africa; Africa, Central; Black People; Blood Chemical Analysis; Child; Chromatography; Genetics, Med | 1964 |
URINARY PHENYLPYRUVIC ACID IN PHENYLKETONURIA.
Topics: Blood Chemical Analysis; Chlorides; Chromatography; Humans; Infant; Infant, Newborn; Iron; Phenylala | 1964 |
SEROTONIN DEFICIENCY IN INFANCY AS ONE CAUSE OF A MENTAL DEFECT IN PHENYLKETONURIA.
Topics: Animals; Animals, Newborn; Behavior; Catecholamines; Chlorpromazine; Genetics; Learning; Metabolic D | 1964 |
AMINO ACID METABOLISM IN KWASHIORKOR. II. METABOLISM OF PHENYLALANINE AND TYROSINE.
Topics: Blood Chemical Analysis; Child; Chromatography; Dietary Proteins; Humans; Infant; Kwashiorkor; Milk; | 1964 |
[METABOLIC ASPECTS OF PHENYLKETONURIA WITH PARTICULAR ATTENTION TO URINARY ELIMINATION OF SOME PHENOLIC ACIDS].
Topics: Adolescent; Attention; Biomedical Research; Child; Humans; Hydroxybenzoates; Indoleacetic Acids; Man | 1964 |
CHEMICAL DIAGNOSIS OF PHENYLKETONURIA. REPORT OF 8 CASES.
Topics: Adolescent; Blood Chemical Analysis; Body Fluids; Child; China; Chromatography; Clinical Laboratory | 1964 |
LEVOMEPROMAZINE (NOZINAN) MEDICATION AS A SOURCE OF ERROR IN THE LABORATORY DIAGNOSIS OF PHENYLKETONURIA.
Topics: Blood; Chlorides; Clinical Laboratory Techniques; Diagnosis; Humans; Indicators and Reagents; Methot | 1965 |
An improved test for phenylketonuria.
Topics: Humans; Phenylketonurias; Phenylpyruvic Acids | 1959 |
The galactose tolerance test in phenylketonuria.
Topics: Body Fluids; Galactose; Humans; Immune Tolerance; Liver; Phenylketonurias; Phenylpyruvic Acids; Urin | 1950 |
Measurement of pleiotropic effects in phenylketonuria.
Topics: Phenylketonurias; Phenylpyruvic Acids | 1951 |
Renal transport of aromatic acids in patients with phenylketonuria.
Topics: Child; Humans; Kidney; Metabolic Clearance Rate; Phenylketonurias; Phenylpyruvic Acids | 1981 |
Phenylpyruvate, fetal damage, and maternal phenylketonuria syndrome.
Topics: Embryonic and Fetal Development; Female; Humans; Infant, Newborn; Phenylketonurias; Phenylpyruvic Ac | 1993 |
Phenylalanine determined in plasma with use of phenylalanine dehydrogenase and a centrifugal analyzer.
Topics: Amino Acid Oxidoreductases; Autoanalysis; Humans; NAD; Phenylalanine; Phenylketonurias; Phenylpyruvi | 1993 |
Measurement of phenyllactate, phenylacetate, and phenylpyruvate by negative ion chemical ionization-gas chromatography/mass spectrometry in brain of mouse genetic models of phenylketonuria and non-phenylketonuria hyperphenylalaninemia.
Topics: Animals; Brain; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Humans; Lactates; Mice | 2000 |
Metabolism of carnitine in phenylacetic acid-treated rats and in patients with phenylketonuria.
Topics: Adult; Animals; Betaine; Carnitine; Female; Glutamic Acid; Homogentisic Acid; Humans; Ketoglutaric A | 2000 |
Phenylalanine and phenylpyruvate inhibit ATP diphosphohydrolase from rat brain cortex.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Cerebra | 2001 |
A synopsis of the unconjugated acidic transamination metabolites of phenylalanine in phenylketonuria.
Topics: Adolescent; Child; Child, Preschool; Female; Humans; Kidney; Lactates; Male; Phenylacetates; Phenyla | 1992 |
Cobalt(II)-catalyzed chemiluminescence in a dioctadecyldimethylammonium chloride bilayer membranous medium for the flow injection determination of phenylpyruvic acid.
Topics: Adult; Cobalt; Flow Injection Analysis; Humans; Lipid Bilayers; Luminescent Measurements; Phenylketo | 1991 |
Examination of urine metabolites in the newborn period and during protein loading tests at 6 months of age--Part 1.
Topics: Creatinine; Dietary Proteins; Humans; Infant, Newborn; Phenylacetates; Phenylketonurias; Phenylpyruv | 1990 |
Excretion of phenylpyruvic, 4-hydroxyphenylpyruvic and indolyl-3-acetic acids by the skin fibroblasts from a phenylketonuric child.
Topics: Adult; Child, Preschool; Epidermis; Female; Fibroblasts; Humans; Indoleacetic Acids; Phenylketonuria | 1988 |
Gas chromatographic analysis of abnormal urinary organic acids in phenylketonuria.
Topics: Adolescent; Adult; Child; Child, Preschool; Chromatography, Gas; Female; Humans; Lactates; Male; Phe | 1985 |
Phenylalanine metabolites, attention span and hyperactivity.
Topics: Adolescent; Attention; Child; Child, Preschool; Female; Humans; Hyperkinesis; Infant; Infant, Newbor | 1985 |