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phenylmethylsulfonyl fluoride and Thalassemia

phenylmethylsulfonyl fluoride has been researched along with Thalassemia in 1 studies

Phenylmethylsulfonyl Fluoride: An enzyme inhibitor that inactivates IRC-50 arvin, subtilisin, and the fatty acid synthetase complex.
phenylmethanesulfonyl fluoride : An acyl fluoride with phenylmethanesulfonyl as the acyl group.

Thalassemia: A group of hereditary hemolytic anemias in which there is decreased synthesis of one or more hemoglobin polypeptide chains. There are several genetic types with clinical pictures ranging from barely detectable hematologic abnormality to severe and fatal anemia.

Research Excerpts

ExcerptRelevanceReference
"beta-Thalassemia is an inherited human disorder which is characterized by a deficient production of hemoglobin beta chains and an attendant accumulation of structurally normal alpha chains in the erythropoietic cells."1.27ATP-dependent proteolysis of hemoglobin alpha chains in beta-thalassemic hemolysates is ubiquitin-dependent. ( Shaeffer, JR, 1988)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shaeffer, JR1

Other Studies

1 other study available for phenylmethylsulfonyl fluoride and Thalassemia

ArticleYear
ATP-dependent proteolysis of hemoglobin alpha chains in beta-thalassemic hemolysates is ubiquitin-dependent.
    The Journal of biological chemistry, 1988, Sep-25, Volume: 263, Issue:27

    Topics: Adenosine Triphosphate; Antibodies; Cell-Free System; Ethylmaleimide; Globins; Hemoglobins; Humans;

1988