phenylmethylsulfonyl fluoride has been researched along with Peripheral Nervous System Diseases in 7 studies
Phenylmethylsulfonyl Fluoride: An enzyme inhibitor that inactivates IRC-50 arvin, subtilisin, and the fatty acid synthetase complex.
phenylmethanesulfonyl fluoride : An acyl fluoride with phenylmethanesulfonyl as the acyl group.
Peripheral Nervous System Diseases: Diseases of the peripheral nerves external to the brain and spinal cord, which includes diseases of the nerve roots, ganglia, plexi, autonomic nerves, sensory nerves, and motor nerves.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The hens were pretreated 24h earlier with PMSF and subsequently treated with a single dosage of 750 mg/kg TOCP, then sacrificed on the corresponding time points of 0, 1, 5, 10, and 21 days after dosing TOCP, respectively." | 1.35 | Phenylmethylsulfonyl fluoride protects against the degradation of neurofilaments in tri-ortho-cresyl phosphate (TOCP) induced delayed neuropathy. ( Dou, D; Song, F; Xie, K; Yan, Y; Zhang, C; Zhao, X, 2009) |
| " When dosed subcutaneously, the tissue concentration of dipterex was high in the brain, spinal cord and muscle at 3 hr after dosing and then concentrated in the spinal cord and muscle for the subsequent 3 hr." | 1.30 | Pharmacokinetics and neurotoxicity of dipterex in hens. A comparative study of administration methods. ( Piao, FY; Tian, Y; Xie, X; Yamauchi, T, 1998) |
| "The induction of central-peripheral distal axonopathy in hens singly dosed with some organophosphorus (OP) compounds, such as di-n-butyl-2,2-dichlorovinyl phosphate (DBDCVP), requires greater than 80% organophosphorylation and subsequent intramolecular rearrangement ("aging") of a protein [neuropathy target esterase (NTE)] in the axon." | 1.27 | Progressive deficit of retrograde axonal transport is associated with the pathogenesis of di-n-butyl dichlorvos axonopathy. ( Lotti, M; Moretto, A; Sabri, MI; Spencer, PS, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Song, F | 1 |
| Yan, Y | 1 |
| Zhao, X | 1 |
| Dou, D | 1 |
| Zhang, C | 1 |
| Xie, K | 1 |
| Baker, T | 1 |
| Lowndes, HE | 1 |
| Johnson, MK | 1 |
| Sandborg, IC | 1 |
| Peraica, M | 2 |
| Moretto, A | 3 |
| Lotti, M | 3 |
| Harp, P | 1 |
| Tanaka, D | 1 |
| Pope, CN | 1 |
| Xie, X | 1 |
| Piao, FY | 1 |
| Tian, Y | 1 |
| Yamauchi, T | 1 |
| Bertolazzi, M | 1 |
| Capodicasa, E | 1 |
| Richardson, RJ | 1 |
| Scapellato, ML | 1 |
| Sabri, MI | 1 |
| Spencer, PS | 1 |
7 other studies available for phenylmethylsulfonyl fluoride and Peripheral Nervous System Diseases
| Article | Year |
|---|---|
Phenylmethylsulfonyl fluoride protects against the degradation of neurofilaments in tri-ortho-cresyl phosphate (TOCP) induced delayed neuropathy.
Topics: Animals; Blotting, Western; Chickens; Female; Neurofilament Proteins; Neurotoxicity Syndromes; Pepti | 2009 |
The effects of phenylmethanesulfonyl fluoride on delayed organophosphorus neuropathy.
Topics: Action Potentials; Animals; Cats; Esterases; Isoflurophate; Motor Neurons; Muscle Contraction; Perip | 1980 |
Selective promotion by phenylmethanesulfonyl fluoride of peripheral and spinal cord neuropathies initiated by diisopropyl phosphorofluoridate in the hen.
Topics: Animals; Ataxia; Axons; Brain; Carboxylic Ester Hydrolases; Chickens; Drug Interactions; Enzyme Inhi | 1995 |
Potentiation of organophosphorus-induced delayed neurotoxicity following phenyl saligenin phosphate exposures in 2-, 5-, and 8-week-old chickens.
Topics: Age Factors; Animals; Axons; Carboxylic Ester Hydrolases; Chickens; Drug Synergism; Enzyme Inhibitor | 1997 |
Pharmacokinetics and neurotoxicity of dipterex in hens. A comparative study of administration methods.
Topics: Administration, Oral; Animals; Body Weight; Brain; Chickens; Cholinesterase Inhibitors; Esterases; F | 1998 |
Phenylmethanesulfonyl fluoride elicits and intensifies the clinical expression of neuropathic insults.
Topics: Aging; Animals; Carboxylic Ester Hydrolases; Chickens; Female; Hexanones; Peripheral Nervous System | 1992 |
Progressive deficit of retrograde axonal transport is associated with the pathogenesis of di-n-butyl dichlorvos axonopathy.
Topics: Animals; Axonal Transport; Axons; Carboxylic Ester Hydrolases; Chickens; Dichlorvos; Female; Kinetic | 1987 |