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phenylmethylsulfonyl fluoride and Nerve Degeneration

phenylmethylsulfonyl fluoride has been researched along with Nerve Degeneration in 3 studies

Phenylmethylsulfonyl Fluoride: An enzyme inhibitor that inactivates IRC-50 arvin, subtilisin, and the fatty acid synthetase complex.
phenylmethanesulfonyl fluoride : An acyl fluoride with phenylmethanesulfonyl as the acyl group.

Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.

Research Excerpts

ExcerptRelevanceReference
"The induction of central-peripheral distal axonopathy in hens singly dosed with some organophosphorus (OP) compounds, such as di-n-butyl-2,2-dichlorovinyl phosphate (DBDCVP), requires greater than 80% organophosphorylation and subsequent intramolecular rearrangement ("aging") of a protein [neuropathy target esterase (NTE)] in the axon."1.27Progressive deficit of retrograde axonal transport is associated with the pathogenesis of di-n-butyl dichlorvos axonopathy. ( Lotti, M; Moretto, A; Sabri, MI; Spencer, PS, 1987)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Massicotte, C1
Inzana, KD1
Ehrich, M1
Jortner, BS1
Pope, CN1
Chapman, ML1
Tanaka, D1
Padilla, S1
Moretto, A1
Lotti, M1
Sabri, MI1
Spencer, PS1

Other Studies

3 other studies available for phenylmethylsulfonyl fluoride and Nerve Degeneration

ArticleYear
Neuropathologic effects of phenylmethylsulfonyl fluoride (PMSF)-induced promotion and protection in organophosphorus ester-induced delayed neuropathy (OPIDN) in hens.
    Neurotoxicology, 1999, Volume: 20, Issue:5

    Topics: Animals; Brain; Chickens; Female; Nerve Degeneration; Nerve Fibers; Nervous System Diseases; Organop

1999
Phenylmethylsulfonyl fluoride alters sensitivity to organophosphorus-induced delayed neurotoxicity in developing animals.
    Neurotoxicology, 1992,Summer, Volume: 13, Issue:2

    Topics: Animals; Carboxylic Ester Hydrolases; Chickens; Drug Synergism; Female; Isoflurophate; Nerve Degener

1992
Progressive deficit of retrograde axonal transport is associated with the pathogenesis of di-n-butyl dichlorvos axonopathy.
    Journal of neurochemistry, 1987, Volume: 49, Issue:5

    Topics: Animals; Axonal Transport; Axons; Carboxylic Ester Hydrolases; Chickens; Dichlorvos; Female; Kinetic

1987