phenylmethylsulfonyl fluoride has been researched along with Nerve Degeneration in 3 studies
Phenylmethylsulfonyl Fluoride: An enzyme inhibitor that inactivates IRC-50 arvin, subtilisin, and the fatty acid synthetase complex.
phenylmethanesulfonyl fluoride : An acyl fluoride with phenylmethanesulfonyl as the acyl group.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
Excerpt | Relevance | Reference |
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"The induction of central-peripheral distal axonopathy in hens singly dosed with some organophosphorus (OP) compounds, such as di-n-butyl-2,2-dichlorovinyl phosphate (DBDCVP), requires greater than 80% organophosphorylation and subsequent intramolecular rearrangement ("aging") of a protein [neuropathy target esterase (NTE)] in the axon." | 1.27 | Progressive deficit of retrograde axonal transport is associated with the pathogenesis of di-n-butyl dichlorvos axonopathy. ( Lotti, M; Moretto, A; Sabri, MI; Spencer, PS, 1987) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (33.33) | 18.7374 |
1990's | 2 (66.67) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Massicotte, C | 1 |
Inzana, KD | 1 |
Ehrich, M | 1 |
Jortner, BS | 1 |
Pope, CN | 1 |
Chapman, ML | 1 |
Tanaka, D | 1 |
Padilla, S | 1 |
Moretto, A | 1 |
Lotti, M | 1 |
Sabri, MI | 1 |
Spencer, PS | 1 |
3 other studies available for phenylmethylsulfonyl fluoride and Nerve Degeneration
Article | Year |
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Neuropathologic effects of phenylmethylsulfonyl fluoride (PMSF)-induced promotion and protection in organophosphorus ester-induced delayed neuropathy (OPIDN) in hens.
Topics: Animals; Brain; Chickens; Female; Nerve Degeneration; Nerve Fibers; Nervous System Diseases; Organop | 1999 |
Phenylmethylsulfonyl fluoride alters sensitivity to organophosphorus-induced delayed neurotoxicity in developing animals.
Topics: Animals; Carboxylic Ester Hydrolases; Chickens; Drug Synergism; Female; Isoflurophate; Nerve Degener | 1992 |
Progressive deficit of retrograde axonal transport is associated with the pathogenesis of di-n-butyl dichlorvos axonopathy.
Topics: Animals; Axonal Transport; Axons; Carboxylic Ester Hydrolases; Chickens; Dichlorvos; Female; Kinetic | 1987 |