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phenylmethylsulfonyl fluoride and Necrosis

phenylmethylsulfonyl fluoride has been researched along with Necrosis in 4 studies

Phenylmethylsulfonyl Fluoride: An enzyme inhibitor that inactivates IRC-50 arvin, subtilisin, and the fatty acid synthetase complex.
phenylmethanesulfonyl fluoride : An acyl fluoride with phenylmethanesulfonyl as the acyl group.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"Phenylmethylsulfonyl fluoride (PMSF) administration to rats, was effective in partially preventing liver necrosis induced by thioacetamide, dimethylnitrosamine or galactosamine, when given 6 hr after the hepatotoxins."7.66Late preventive effects on dimethylnitrosamine, thioacetamide or galactosamine-induced liver necrosis of the inhibitor of proteases, phenylmethylsulfonyl fluoride. ( Castro, JA; de Fenos, OM; de Ferreyra, EC, 1983)
"Necrosis was observed in both the lymphocyte and monocyte/granulocyte gates."1.33A study of zearalenone cytotoxicity on human peripheral blood mononuclear cells. ( Krambovitis, E; Porichis, F; Tsatsakis, A; Tzanakakis, G; Vlata, Z, 2006)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vlata, Z1
Porichis, F1
Tzanakakis, G1
Tsatsakis, A1
Krambovitis, E1
de Ferreyra, EC3
de Fenos, OM3
Castro, JA3
Villarruel, MC1
Fernández, G1
Bernacchi, AS1
de Castro, CR1

Other Studies

4 other studies available for phenylmethylsulfonyl fluoride and Necrosis

ArticleYear
A study of zearalenone cytotoxicity on human peripheral blood mononuclear cells.
    Toxicology letters, 2006, Sep-10, Volume: 165, Issue:3

    Topics: Ammonium Chloride; Apoptosis; Calcium; Cell Proliferation; Cells, Cultured; Estrogens, Non-Steroidal

2006
Late preventive effects on dimethylnitrosamine, thioacetamide or galactosamine-induced liver necrosis of the inhibitor of proteases, phenylmethylsulfonyl fluoride.
    Research communications in chemical pathology and pharmacology, 1983, Volume: 42, Issue:3

    Topics: Acetamides; Animals; Dimethylnitrosamine; Drug Evaluation, Preclinical; Galactosamine; Liver; Male;

1983
Late preventive effects of phenylmethylsulfonyl-fluoride on carbon tetrachloride-induced liver necrosis.
    Toxicology letters, 1984, Volume: 21, Issue:2

    Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injur

1984
Further studies on the mechanism of the late protective effects of phenylmethylsulfonyl fluoride on carbon tetrachloride-induced liver necrosis.
    Experimental and molecular pathology, 1989, Volume: 50, Issue:2

    Topics: Administration, Oral; Animals; Body Temperature; Calcium; Carbon Radioisotopes; Carbon Tetrachloride

1989