Page last updated: 2024-08-17

phenylethyl alcohol and Disease Models, Animal

phenylethyl alcohol has been researched along with Disease Models, Animal in 131 studies

Research

Studies (131)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (0.76)18.2507
2000's31 (23.66)29.6817
2010's82 (62.60)24.3611
2020's17 (12.98)2.80

Authors

AuthorsStudies
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Desoky, AA; Elharrif, MG; Elmaksoud, HAA; Ibrahimi, A; Motawea, MH1
Gur, C; Ileriturk, M; Kandemir, FM; Kaynar, O; Semis, HS1
Anpilogov, K; Beccari, T; Bertelli, M; Bhusan Tripathi, Y; Ceccarini, MR; Cecchin, S; Coatto, M; Dhuli, K; Donato, K; Michelini, S; Mishra, P; Pandey, N; Paolacci, S; Tripathi, P1
Cao, Y; Qiu, Z; Song, M; Tian, W; Wang, C; Wang, Q; Xiao, J1
Miao, F1
Andrieu, P; Cabeza, L; Cramoisy, S; Haffen, E; Houdayer, C; Millot, JL; Peterschmitt, Y; Ramadan, B; Risold, PY1
Cañuelo, A; Garcia-Moreno, JC; Martínez-Lara, E; Porta de la Riva, M; Siles, E1
Bustamante, A; Echeverría, F; Espinosa, A; Gonzalez-Mañán, D; Illesca, P; Orellana, P; Ortiz, M; Soto-Alarcón, SA; Valenzuela, R; Videla, LA1
Chernysheva, GA; Khodanovich, MY; Kisel', AA; Krutenkova, EP; Kudabaeva, MS; Plotnikov, MB; Smol'yakova, VI; Tyumentseva, YА1
He, W; Huang, Y; Li, M; Li, W; Luo, Y; Mei, Y; Pan, H; Wan, T; Wang, Q; Wang, Z; Xue, J; Zhang, Y1
Aksu Kızıldağ, C; Albayrak, M; Arabacı, T; Balseven, HM; Kızıldağ, A; Tasdemir, U1
Alrais, M; Blackwell, SC; Facchinetti, F; Liu, C; Longo, M; Menichini, D; Sibai, BM; Xia, Y1
Akcay, E; Palaz, MN1
Brunetti, G; Calabrese, V; Di Rosa, G; Leri, M; Saul, N; Schmitz-Linneweber, C; Scuto, M; Stefani, M1
Cantürk Tan, F; Ceylan, T; Kaymak, E; Yakan, B1
Chen, Y; Fang, Q; Jiang, DS; Zhang, Y1
Cao, Y; Du, Q; Jiang, Y; Jiao, X; Li, Y; Liu, X; Tang, M; Tian, C; Wang, Y; Wang, Z; Xie, P; Yang, J1
Hu, C; Liu, Y; Shen, L; Yin, H; Zeng, J; Zhang, K; Zhang, L; Zhao, YT; Zheng, W1
Cellat, M; Dikmen, N; Etyemez, M; Gökçek, İ; Güvenç, M; İşler, CT; Kuzu, M; Türk, E; Uyar, A1
Amiot, MJ; Peyrol, J; Riva, C1
Dokuyucu, R; Gökçe, H; Gülmez, Mİ; Okuyucu, Ş1
He, Y; Jing, T; Li, Y; Lin, R; Wang, B; Wang, W; Wei, J; Xiao, Y; Yang, X; Zhang, J; Zhang, W1
Chen, S; Deng, W; Li, J; Liao, H; Ren, J; Tang, Q; Xu, L; Yang, Z; Zhang, N1
Kırzıoğlu, FY; Nazıroğlu, M; Özmen, Ö; Uğuz, AC; Yiğit, U1
Khan, MN; Lane, ME; McCarron, PA; Tambuwala, MM1
Deveci, HA; Karapehlivan, M1
Cara, FE; El-Azem, N; Granados-Principal, S; Pulido-Moran, M; Quiles, JL; Ramirez-Tortosa, CL; Ramirez-Tortosa, M; Sanchez-Rovira, P1
Hang, C; Liao, K; Sun, L1
Casamenti, F; Lapucci, A; Nardiello, P; Pantano, D; Stefani, M1
Agüera, E; Aguilar-Luque, M; Conde, C; Escribano, BM; Feijóo, M; Giraldo, AI; LaTorre, M; Lillo, R; Luque, E; Ochoa, JJ; Santamaría, A; Túnez, I1
Aliev, OI; Anishchenko, AM; Arkhipov, AM; Fomina, TI; Plotnikov, MB; Plotnikova, TM; Shamanaev, AY; Sidekhmenova, AV1
Balkhi, HM; Gul, T; Haq, E; Sana, S1
de Roos, B; Duthie, GG; Fernández-Bolaños, J; Gómez-Carretero, A; Maya, I; Rodríguez-Gutiérrez, G; Rubio-Senent, F1
Dos Santos, JS; Monte-Alto-Costa, A; Romana-Souza, B1
ArunSundar, M; Ravichandiran, V; Shanmugarajan, TS1
Dhammu, TS; Khan, H; Khan, M; Shunmugavel, A; Singh, AK; Singh, I1
Kesharwani, P; McCarron, PA; Shukla, R; Tambuwala, MM; Thompson, PD1
Khan, MN; McCarron, PA; Tambuwala, MM; Thompson, P1
Fabiani, R; Fuccelli, R; Rosignoli, P1
Cheng, CC; Chi, PL; Huang, WC; Liu, CP; Shen, MC; Shu, CW; Tseng, CJ; Wann, SR1
Chen, C; Huang, L; Jia, Y; Jiang, S; Lu, G; Sun, X; Xie, Y1
Arai, T; Araki, W; Araki, YM; Itoh, M; Kametani, F; Mamada, N; Mizusawa, H; Saitoh, A; Sakai, Y; Sekiguchi, M; Tamaoka, A; Taniguchi, K; Wada, K; Yamada, D; Yamamoto, F; Yang, J1
Astiz, S; Encinas, T; Garcia-Contreras, C; Gonzalez-Bulnes, A; Heras-Molina, A; Isabel, B; Nieto, R; Ovilo, C; Pardo, Z; Torres-Rovira, L; Vazquez-Gomez, M1
Akdemir, F; Evliyaoglu, O; Evsen, MS; Ozler, A; Sak, ME; Soydinc, HE; Turgut, A; Turkcu, G1
Bai, H; Chen, H; Hai, C; Li, W; Liang, X; Liu, R; Qin, X; Wang, X; Zhang, W; Zhang, X1
Jiang, H; Kang, K; Liu, L; Ma, Y; Pan, H; Pan, S; Sun, B; Sun, X; Wang, D; Wang, J1
Hong, S; Jung, Y; Kim, H; Kim, W; Kwak, MK; Lee, JW; Na, DH; Oh, JE; Park, EJ; Yum, S1
Guan, S; Huang, G; Lu, J; Song, B; Wang, Z; Xiong, Y; Xu, L; Zhuang, S1
Bayram, E; Karakaya, P; Kurul, SH; Özbal, S; Topçu, Y; Tuğyan, K; Yilmaz, O; Yiş, U1
Aşçı, M; Bostan, B; Erdem, M; Gülabi, D; Güneş, T; Köseoğlu, RD1
İlhan, S; Motor, S; Nacar, E; Oktar, S; Şahna, E; Yılmaz, N1
Akyol, O; Akyol, S; Balci, M; Cakmak, O; Erden, G; Gurel, A; Ugurcu, V1
Arunsundar, M; Ravichandran, V; Shanmugarajan, TS1
Hussain, Z; Katas, H; Kumolosasi, E; Mohd Amin, MC1
Bae, ON; Bae, S; Kim, ES; Koo, JE; Lee, JY; Lim, KM1
de Roos, B; Duthie, G; Fernández-Bolaños, J; Rodríguez-Gutiérrez, G; Rubio-Senent, F1
Brites, D; Bronze, MR; Direito, R; Fernandes, A; Fernandes, E; Figueira, ME; Freitas, M; Rocha, J; Sepodes, B; Silva, S1
Choi, JH; Ha, SM; Jung, SY; Kang, MS; Lee, JH; Oh, H; Park, S; Park, SJ; Roh, KH; Song, H; Yang, JW1
Cantley, MD; Crotti, TN; Dharmapatni, AA; Gibson, RJ; Haynes, DR; Marino, V; Perilli, E; Stansborough, RL; Xu, J; Zawawi, MS1
Alici, O; Alici, S; Altintas, ND; Aydin, M; Kavakli, HS; Koca, C1
Alp, H; Evliyaoglu, O; Firat, U; Gelincik, I; Kapan, M; Onder, A; Senol, S; Tekin, R; Tokgoz, O1
Chen, RC; Fan, W; Liu, ZH1
Akyol, O; Akyol, S; Armutcu, F; Erdemli, HK1
Guo, L; Li, Y; Shi, L; Shi, Y; Song, M; Yu, J1
Cai, XM; Chen, J; Gong, JB; Pei, YH; Wang, X; Xie, L; Yang, RH1
Calignano, A; Canani, RB; Di Guida, F; Lama, A; Magliocca, S; Meli, R; Mollica, MP; Paciello, O; Pagano, TB; Pirozzi, C; Raso, GM; Russo, R; Simeoli, R1
Naidu, KA; Reddy, KVK1
Bastlund, JF; Becker, R; Didriksen, M; Gass, N; Meyer-Lindenberg, A; Sartorius, A; Schwarz, AJ; Stensbøl, TB; Weber-Fahr, W1
Baykal, B; Elbey, B; Keskin, I; Kuş, S; Şahin, A; Yazgan, ÜC; Yılmaz, A1
Hou, C; Jia, L; Li, C; Li, Y; Liu, J; Long, J; Peng, Y; Shi, L; Tang, Y; Yang, Z1
Abadie, J; Beck, L; Gauthier, O; Guicheux, J; Hivernaud, V; Houard, X; Krisa, S; Lesoeur, J; Masson, M; Merceron, C; Mével, E; Nourissat, G; Richard, T; Urban, N; Vinatier, C; Wittrant, Y1
Acquaviva, R; Di Giacomo, C; Pittalà, V; Romeo, G; Salerno, L; Sorrenti, V1
Choi, JY; Jeong, S; Jung, Y; Kim, ND; Lee, HE; Lee, JY; Park, HH; Yang, G1
Andreadou, I; Brown, L; Efentakis, P; Gikas, E; Halabalaki, M; Lemonakis, N; Poudyal, H; Skaltsounis, L1
Brown, L; Gikas, E; Halabalaki, M; Lemonakis, N; Poudyal, H; Skaltsounis, AL; Tsarbopoulos, A1
Abdullah, HI; Durdagi, S; Duruyurek, M; Ekhteiari Salmas, R; Gulhan, MF; Selamoglu, Z1
Agalias, A; Coxam, V; Davicco, MJ; Horcajada, MN; Lebecque, P; Mardon, J; Mazur, A; Puel, C; Skaltsounis, AL1
Maulik, N; Paul, D; Penumathsa, SV; Samuel, SM; Thirunavukkarasu, M1
Hennig, B; MacDonald, R; Oesterling, E; Shen, H; Stromberg, A; Toborek, M1
Ciçek, E; Gökalp, O; Ozçelik, N; Ozer, MK; Uz, E; Yilmaz, HR1
Battino, M; Bullon, P; Goteri, G; Granados-Principal, S; Morillo, JM; Quiles, JL; Ramirez-Tortosa, M; Rubini, C1
Bagci, C; Bilgic, T; Buyukberber, M; Ceylan, NO; Gulsen, MT; Koruk, M; Savaş, MC; Tutar, E1
Aydin, M; Davarci, M; Gökçe, A; Ilhan, S; Oktar, S; Ozkan, OV; Yalçinkaya, FR; Yönden, Z1
Brown, L; Campbell, F; Poudyal, H1
Ateş, B; Erdoğan, A; Eşrefoğlu, M; Gül, M1
Gomonchareonsiri, S; Thamprasert, K; Wongmekiat, O1
Aliev, OI; Chernyshova, GA; Krasnov, EA; Plotnikov, MB; Smol'iakova, VI1
Andiran, F; Haltas, H; Hirfanoglu, IM; Kosus, A; Tatli, MM; Tayman, C; Tonbul, A; Uysal, S1
Bordignon-Luiz, MT; Ferreira, EA; Filho, DW; Gris, EF; Mattivi, F; Pedrosa, RC; Vrhovsek, U1
de la Torre, R; Hinojosa, AJ; Pontes, AJ; Tasset, I; Túnez, I1
Cherif, M; Elgaaied, AB; Hamden, K; Hamrita, B; Jaouadi, B; Kouidi, S; Medimegh, I; Messai, Y; Ouerhani, S; Rouissi, K1
Alarcón de la Lastra, C; Cárdeno, A; Sánchez de Ibargüen, L; Sánchez-Fidalgo, S1
Feng, SF; Li, XQ; Liu, SB; Shi, TY; Tian, Z; Wu, YM; Xing, JH; Zhang, N; Zhao, MG1
Dash, PK; Moore, AN; Pati, S; Redell, JB; Zhang, M; Zhao, J1
Du, Y; Farlow, MR; Fontanilla, CV; Johnstone, B; Pascuzzi, RM; Wei, X; Zhao, L1
Hisatsune, A; Isohama, Y; Katsuki, H; Kurauchi, Y; Mishima, S1
Beltrán-Ramírez, O; Pérez, RM; Sierra-Santoyo, A; Villa-Treviño, S1
Cantlay, LL; de Roos, B; Duthie, GG; Fernández-Bolaños Guzmán, J; Horgan, GW; Kelder, T; Morrice, P; Nicol, F; Reid, M; Rodríguez-Gutiérrez, G; Wood, S1
Carvalho, LR; Castiglia, YM; Correa, RR; de Oliveira, CC; de Souza, AV; Roso, NC; Scatena, LM; Vianna, PT1
Atar, M; Bodakcı, MN; Bozkurt, M; Bozkurt, Y; Hatipoglu, NK; Kıbrıslı, E; Penbegul, N; Sancaktutar, AA; Soylemez, H; Turkçu, G; Yavuz, C; Yuksel, H1
Agackıran, Y; Atik, D; Delibas, N; Ginis, Z; Koylu, H; Sırmalı, M; Sırmalı, R; Solak, O; Tezel, C1
Akoglu, M; Bostanci, EB; Duzcan, SE; Kelten, EC; Sacar, S; Simsek, NG; Teke, Z; Yenisey, C1
Choi, J; Jeong, E; Kim, SY; Koo, JE; Lee, JY; Lim, KM; Park, ZY; Seo, YJ; Tyagi, N1
Baffa, O; Barbosa, F; Barros Silva, R; Del-Bel, E; Ferreira, DA; Kinoshita, A; Martins, NM; Oliveira Souza, VC; Santos, AC; Santos, NA1
Buang, F; Hussain, Z; Katas, H; Kumolosasi, E; Mohd Amin, MC; Sahudin, S1
Akyol, O; Güleç, M; Ozyurt, H; Sahin, S; Söğüt, S; Uz, E; Var, A1
Ayan, I; Bora, A; Elmali, N; Germen, B; Mizrak, B; Türköz, Y1
Bockaert, J; Briant, L; Courseau, AS; de Bock, F; Lerner-Natoli, M; Montpied, P; Niel, G; Rondouin, G1
Burke, WJ; Li, SW; Nonneman, R; Williams, EA; Zahm, DS1
Arce-Popoca, E; Carrasco-Legleu, CE; Fattel-Fazenda, S; Márquez-Rosado, L; Pérez-Carreón, JI; Villa-Treviño, S1
Akyol, O; Armutcu, F; Gurel, A; Ilhan, A; Iraz, M; Oztas, E1
Akyol, O; Gulec, M; Iraz, M; Kalcioglu, MT; Kizilay, A; Ozerol, E; Ozturan, O1
Altinyazar, C; Armutcu, F; Gurel, A; Hosnuter, M; Kargi, E; Unalacak, M1
Nishioka, N; Tsuji, T; Yoshizumi, K1
Atik, U; Cinel, L; Değirmenci, U; Kanik, A; Oz, O; Tamer, L; Vatansever, H; Yildirim, O; Yilmaz, A1
Akyol, O; Bagci, C; Cagli, K; Cavdar, S; Cengiz, B; Dinckan, H; Gulec, M; Pence, S; Sari, I1
Chih, CL; Huang, SS; Liao, PH; Lin, MJ; Lin, RH; Lin, SM; Liu, SM; Tsai, SK; Yang, CY1
Erdogan, S; Fadillioglu, E; Iraz, M; Tasdemir, S1
Agalias, A; Coxam, V; Davicco, MJ; Horcajada, MN; Kati-Coulibaly, S; Lebecque, P; Mardon, J; Obled, C; Puel, C; Rock, E; Skaltsounis, LA1
Ansari, MA; Elango, C; Khan, M; Singh, AK; Singh, I1
Celik, S; Erdogan, S; Gorur, S; Hakverdi, S; Ocak, S1
Güney, M; Karahan, N; Mungan, T; Nasir, S; Oral, B1
Choi, I; Choi, IW; Choi, YH; Jung, WK; Kang, MS; Kim, SK; Lee, DY; Lee, SW; Park, SG; Seo, SK; Yea, SS1
Altuğ, E; Atik, E; Avci, G; Kontas, T; Serarslan, G1
Alhan, E; Ates, B; Ercin, C; Erdogan, S; Kaklikkaya, N; Kural Vanizor, B; Topaloglu, S; Turkyilmaz, S1
Abrahamyan, H; Gabrielyan, E; Hovhannisyan, A; Nikoyan, N; Ohanyan, N; Panossian, A; Wikman, G1
Capasso, G; Ciarcia, R; Damiano, S; Della Ragione, F; Di Gennaro, CI; Florio, S; Galletti, P; Manna, C; Mazzoni, O; Perna, A; Pollastro, RM; Zappia, V1
Choi, I; Choi, IW; Choi, YH; Jeon, YJ; Jung, WK; Kim, SK; Lee, CM; Lee, DY; Lee, SW; Park, SG; Seo, SK; Yea, SS1
Akyol, O; Ciralik, H; Ilhan, A; Koltuksuz, U; Ozen, S; Uz, E1
Fitzpatrick, LR; Le, T; Wang, J1

Reviews

3 review(s) available for phenylethyl alcohol and Disease Models, Animal

ArticleYear
Hydroxytyrosol in the Prevention of the Metabolic Syndrome and Related Disorders.
    Nutrients, 2017, Mar-20, Volume: 9, Issue:3

    Topics: Adiposity; Animals; Antioxidants; Body Weight; Diet, Mediterranean; Disease Models, Animal; Homeostasis; Humans; Hyperglycemia; Lipid Metabolism; Metabolic Syndrome; Olive Oil; Oxidative Stress; Phenylethyl Alcohol; Polyphenols

2017
Caffeic acid phenethyl ester: its protective role against certain major eye diseases.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2014, Volume: 30, Issue:9

    Topics: Animals; Bees; Caffeic Acids; Disease Models, Animal; Eye Diseases; Humans; NF-kappa B; Phenylethyl Alcohol; Propolis

2014
Therapeutic Potential of Caffeic Acid Phenethyl Ester (CAPE) in Diabetes.
    Current medicinal chemistry, 2018, Volume: 25, Issue:37

    Topics: Animals; Antioxidants; Caffeic Acids; Diabetes Complications; Diabetes Mellitus; Disease Models, Animal; Disease Progression; Humans; Oxidative Stress; Phenylethyl Alcohol; Polyphenols

2018

Other Studies

128 other study(ies) available for phenylethyl alcohol and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
Hydroxytyrosol alleviate intestinal inflammation, oxidative stress and apoptosis resulted in ulcerative colitis.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 142

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Colitis, Ulcerative; Cytokines; Disease Models, Animal; Inflammation; Male; Olea; Oxidative Stress; Phenylethyl Alcohol; Plant Extracts; Rats

2021
Investigation of the anti-inflammatory effects of caffeic acid phenethyl ester in a model of λ-Carrageenan-induced paw edema in rats.
    Human & experimental toxicology, 2021, Volume: 40, Issue:12_suppl

    Topics: Animals; Anti-Inflammatory Agents; Caffeic Acids; Carrageenan; Disease Models, Animal; Edema; Male; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley

2021
Effect of a dietary supplement on the reduction of lymphedema-progression in mouse tail-cut model.
    European review for medical and pharmacological sciences, 2021, Volume: 25, Issue:1 Suppl

    Topics: Animals; Citrus; Dietary Supplements; Disease Models, Animal; Disease Progression; Lymphedema; Mice; Olea; Oryza; Phenylethyl Alcohol; Plant Extracts; Tail; Treatment Outcome; Vitamin A; Wound Healing

2021
Hydroxytyrosol Alleviates Dextran Sulfate Sodium-Induced Colitis by Modulating Inflammatory Responses, Intestinal Barrier, and Microbiome.
    Journal of agricultural and food chemistry, 2022, Feb-23, Volume: 70, Issue:7

    Topics: Animals; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Phenylethyl Alcohol

2022
Hydroxytyrosol alleviates dextran sodium sulfate-induced colitis by inhibiting NLRP3 inflammasome activation and modulating gut microbiota in vivo.
    Nutrition (Burbank, Los Angeles County, Calif.), 2022, Volume: 97

    Topics: Animals; Antioxidants; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Inflammasomes; Inflammatory Bowel Diseases; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Phenylethyl Alcohol; Sulfates

2022
Beneficial effects of prolonged 2-phenylethyl alcohol inhalation on chronic distress-induced anxio-depressive-like phenotype in female mice.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 151

    Topics: Animals; Anxiety; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Female; Hypothalamo-Hypophyseal System; Mice; Phenotype; Phenylethyl Alcohol; Pituitary-Adrenal System

2022
Tyrosol, a simple phenol from EVOO, targets multiple pathogenic mechanisms of neurodegeneration in a C. elegans model of Parkinson's disease.
    Neurobiology of aging, 2019, Volume: 82

    Topics: alpha-Synuclein; Animals; Animals, Genetically Modified; Antioxidants; Caenorhabditis elegans; Dietary Supplements; Disease Models, Animal; Drug Delivery Systems; Nerve Degeneration; Olive Oil; Parkinsonian Disorders; Phenylethyl Alcohol

2019
Docosahexaenoic acid and hydroxytyrosol co-administration fully prevents liver steatosis and related parameters in mice subjected to high-fat diet: A molecular approach.
    BioFactors (Oxford, England), 2019, Volume: 45, Issue:6

    Topics: Animals; Diet, High-Fat; Dietary Supplements; Disease Models, Animal; Docosahexaenoic Acids; Drug Synergism; Fatty Liver; Humans; Inflammation; Lipid Metabolism; Liver; Mice; Oxidative Stress; Phenylethyl Alcohol; PPAR alpha

2019
p-Tyrosol Enhances the Production of New Neurons in the Hippocampal CA1 Field after Transient Global Cerebral Ischemia in Rats.
    Bulletin of experimental biology and medicine, 2019, Volume: 168, Issue:2

    Topics: Animals; CA1 Region, Hippocampal; Disease Models, Animal; Doublecortin Protein; Ischemic Attack, Transient; Male; Nerve Regeneration; Neurogenesis; Neurons; Neuroprotective Agents; Phenylethyl Alcohol; Rats; Rats, Wistar

2019
FA-97, a New Synthetic Caffeic Acid Phenethyl Ester Derivative, Protects against Oxidative Stress-Mediated Neuronal Cell Apoptosis and Scopolamine-Induced Cognitive Impairment by Activating Nrf2/HO-1 Signaling.
    Oxidative medicine and cellular longevity, 2019, Volume: 2019

    Topics: Alzheimer Disease; Animals; Apoptosis; Caffeic Acids; Cognitive Dysfunction; Disease Models, Animal; Glucosides; Heme Oxygenase-1; Humans; Male; Mice; Mice, Inbred Strains; Neurons; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; PC12 Cells; Phenylethyl Alcohol; Rats; RNA, Small Interfering; Scopolamine; Signal Transduction

2019
A biochemical and immunohistochemical study of the effects of caffeic acid phenethyl ester on alveolar bone loss and oxidative stress in diabetic rats with experimental periodontitis.
    Biotechnic & histochemistry : official publication of the Biological Stain Commission, 2020, Volume: 95, Issue:6

    Topics: Alveolar Bone Loss; Animals; Caffeic Acids; Diabetes Mellitus, Experimental; Disease Models, Animal; Male; Oxidative Stress; Periodontitis; Phenylethyl Alcohol; Rats, Wistar; Streptozocin

2020
Maternal Supplementation of Inositols, Fucoxanthin, and Hydroxytyrosol in Pregnant Murine Models of Hypertension.
    American journal of hypertension, 2020, 07-18, Volume: 33, Issue:7

    Topics: Animals; Antioxidants; Dietary Supplements; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Hypertension; Inositol; Mice; Mice, Knockout; Phenylethyl Alcohol; Pregnancy; Random Allocation; Xanthophylls

2020
The Impact of Propolis Factor Caffeic Acid Phenethyl-Ester on the Cerebral Vasospasm and Early Brain Damage in the Experimentally Induced Subarachnoid Hemorrhage on Rats.
    World neurosurgery, 2020, Volume: 138

    Topics: Animals; CA3 Region, Hippocampal; Caffeic Acids; Disease Models, Animal; Neurons; Neuroprotective Agents; Phenylethyl Alcohol; Propolis; Rats, Wistar; Subarachnoid Hemorrhage; Vasospasm, Intracranial

2020
Healthspan Maintenance and Prevention of Parkinson's-like Phenotypes with Hydroxytyrosol and Oleuropein Aglycone in
    International journal of molecular sciences, 2020, Apr-08, Volume: 21, Issue:7

    Topics: Acetates; alpha-Synuclein; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Cyclopentane Monoterpenes; Disease Models, Animal; Dopaminergic Neurons; Parkinson Disease; Phenylethyl Alcohol; Polyphenols; Pyrans; Treatment Outcome

2020
Research on the protective effect of caffeic acid phenethyl ester on testicular damage caused by cisplatin
    Turkish journal of medical sciences, 2020, 12-17, Volume: 50, Issue:8

    Topics: Animals; Antineoplastic Agents; Caffeic Acids; Cisplatin; Disease Models, Animal; Male; Phenylethyl Alcohol; Rats; Rats, Wistar; Testicular Diseases; Testis

2020
Hydroxytyrosol inhibits apoptosis in ischemia/reperfusion-induced acute kidney injury via activating Sonic Hedgehog signaling pathway.
    European review for medical and pharmacological sciences, 2020, Volume: 24, Issue:23

    Topics: Acute Kidney Injury; Animals; Apoptosis; Cell Survival; Cells, Cultured; Disease Models, Animal; Hedgehog Proteins; Humans; Male; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction

2020
Discovery of CAPE derivatives as dual EGFR and CSK inhibitors with anticancer activity in a murine model of hepatocellular carcinoma.
    Bioorganic chemistry, 2021, Volume: 107

    Topics: Animals; Antineoplastic Agents; Binding Sites; Caffeic Acids; Carcinoma, Hepatocellular; Catalytic Domain; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Drug Screening Assays, Antitumor; ErbB Receptors; Female; Liver Neoplasms; Male; Mice; Molecular Docking Simulation; Phenylethyl Alcohol; src-Family Kinases; Structure-Activity Relationship

2021
Hydroxytyrosol alleviates oxidative stress and neuroinflammation and enhances hippocampal neurotrophic signaling to improve stress-induced depressive behaviors in mice.
    Food & function, 2021, Jun-21, Volume: 12, Issue:12

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Cytokines; Depression; Disease Models, Animal; Hindlimb Suspension; Hippocampus; Inflammation; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Phenylethyl Alcohol; Signal Transduction; Stress, Psychological; Swimming

2021
Tyrosol improves ovalbumin (OVA)-induced asthma in rat model through prevention of airway inflammation.
    Naunyn-Schmiedeberg's archives of pharmacology, 2021, Volume: 394, Issue:10

    Topics: Allergens; Animals; Anti-Inflammatory Agents; Antioxidants; Asthma; Bronchoalveolar Lavage Fluid; Catalase; Cytokines; Disease Models, Animal; Eosinophils; Glutathione; Glutathione Peroxidase; Immunoglobulin E; Leukocyte Count; Lung; NF-kappa B; Ovalbumin; Phenylethyl Alcohol; Rats, Wistar

2021
The effect of caffeic acid phenethyl ester and thymoquinone on otitis media with effusion in rats.
    International journal of pediatric otorhinolaryngology, 2017, Volume: 96

    Topics: Animals; Anti-Inflammatory Agents; Benzoquinones; Caffeic Acids; Disease Models, Animal; Eustachian Tube; Injections, Intraperitoneal; Male; Otitis Media with Effusion; Phenylethyl Alcohol; Rats; Rats, Wistar; Temporal Bone

2017
Hydroxytyrosol Attenuates LPS-Induced Acute Lung Injury in Mice by Regulating Autophagy and Sirtuin Expression.
    Current molecular medicine, 2017, Volume: 17, Issue:2

    Topics: Acute Lung Injury; Animals; Autophagy; Capillary Permeability; Chemokines; Cytokines; Disease Models, Animal; Gene Expression Regulation; Inflammation Mediators; Lipopolysaccharides; Lung; Male; Mice; Models, Molecular; Molecular Conformation; Phenylethyl Alcohol; Sirtuins

2017
Caffeic acid phenethyl ester attenuates pathological cardiac hypertrophy by regulation of MEK/ERK signaling pathway in vivo and vitro.
    Life sciences, 2017, Jul-15, Volume: 181

    Topics: Animals; Blotting, Western; Caffeic Acids; Cardiomegaly; Cell Line; Disease Models, Animal; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Phenylephrine; Phenylethyl Alcohol; Polymerase Chain Reaction; Rats; Resveratrol; Smad Proteins; Stilbenes; Transforming Growth Factor beta

2017
Is caffeic acid phenethyl ester more protective than doxycycline in experimental periodontitis?
    Archives of oral biology, 2017, Volume: 81

    Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Caffeic Acids; Cytokines; Disease Models, Animal; Doxycycline; Enzyme-Linked Immunosorbent Assay; Lipid Peroxidation; Male; Oxidants; Oxidative Stress; Periodontitis; Phenylethyl Alcohol; Rats; Rats, Wistar

2017
Caffeic acid phenethyl ester is protective in experimental ulcerative colitis via reduction in levels of pro-inflammatory mediators and enhancement of epithelial barrier function.
    Inflammopharmacology, 2018, Volume: 26, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Caffeic Acids; Colitis, Ulcerative; Cytokines; Dextran Sulfate; Disease Models, Animal; Epithelial Cells; Female; Inflammation; Inflammation Mediators; Mice, Inbred C57BL; NF-kappa B; Phenylethyl Alcohol; Protective Agents

2018
Chlorpyrifos-induced parkinsonian model in mice: Behavior, histopathology and biochemistry.
    Pesticide biochemistry and physiology, 2018, Volume: 144

    Topics: Animals; Antioxidants; Aryldialkylphosphatase; Brain; Caffeic Acids; Chlorpyrifos; Disease Models, Animal; Insecticides; Lipid Metabolism; Male; Mice; Motor Activity; N-Acetylneuraminic Acid; Neuroprotective Agents; Parkinsonian Disorders; Phenylethyl Alcohol

2018
Modulation by hydroxytyrosol of oxidative stress and antitumor activities of paclitaxel in breast cancer.
    European journal of nutrition, 2019, Volume: 58, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Therapy, Combination; Female; Oxidative Stress; Paclitaxel; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Treatment Outcome; Tumor Burden

2019
Caffeic acid phenethyl ester synergistically enhances the antifungal activity of fluconazole against resistant Candida albicans.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2018, Feb-01, Volume: 40

    Topics: Animals; Antifungal Agents; Caenorhabditis elegans; Caffeic Acids; Candida albicans; Candidiasis; Disease Models, Animal; Drug Resistance, Fungal; Drug Synergism; Drug Therapy, Combination; Fluconazole; Microbial Sensitivity Tests; Phenylethyl Alcohol

2018
Diet Supplementation with Hydroxytyrosol Ameliorates Brain Pathology and Restores Cognitive Functions in a Mouse Model of Amyloid-β Deposition.
    Journal of Alzheimer's disease : JAD, 2018, Volume: 63, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloidosis, Familial; Animals; Antioxidants; Autophagy; Brain; Cognition Disorders; Corneal Dystrophies, Hereditary; Diet; Disease Models, Animal; Glial Fibrillary Acidic Protein; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Phenylethyl Alcohol; Presenilin-1; RNA, Messenger; Signal Transduction; Tumor Necrosis Factor-alpha

2018
The protective effect of extra-virgin olive oil in the experimental model of multiple sclerosis in the rat.
    Nutritional neuroscience, 2020, Volume: 23, Issue:1

    Topics: Animals; Brain; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Male; Multiple Sclerosis; Oleic Acid; Olive Oil; Phenylethyl Alcohol; Rats; Spinal Cord

2020
Effect of p-tyrosol on hemorheological parameters and cerebral capillary network in young spontaneously hypertensive rats.
    Microvascular research, 2018, Volume: 119

    Topics: Age Factors; Animals; Arterial Pressure; Blood Viscosity; Capillaries; Cerebral Cortex; Cerebrovascular Circulation; Cerebrovascular Disorders; Disease Models, Animal; Hemorheology; Hypertension; Microcirculation; Neovascularization, Physiologic; Phenylethyl Alcohol; Rats, Inbred SHR; Rats, Inbred WKY

2018
Anti-glioma Effects of Caffeic Acid Phenethyl Ester and Dasatinib Combination Therapy in an in vivo Rat Glioma Model.
    Anti-cancer agents in medicinal chemistry, 2018, Volume: 18, Issue:12

    Topics: Animals; Antineoplastic Agents; Caffeic Acids; Cell Proliferation; Dasatinib; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Therapy, Combination; Glioma; Male; Molecular Structure; Phenylethyl Alcohol; Rats; Rats, Wistar; Structure-Activity Relationship; Tumor Cells, Cultured

2018
Selenium and sulphur derivatives of hydroxytyrosol: inhibition of lipid peroxidation in liver microsomes of vitamin E-deficient rats.
    European journal of nutrition, 2019, Volume: 58, Issue:5

    Topics: Animals; Disease Models, Animal; Lipid Peroxidation; Microsomes, Liver; Phenylethyl Alcohol; Rats; Selenium; Sulfur; Vitamin E Deficiency

2019
Caffeic acid phenethyl ester promotes wound healing of mice pressure ulcers affecting NF-κB, NOS2 and NRF2 expression.
    Life sciences, 2018, Aug-15, Volume: 207

    Topics: Animals; Caffeic Acids; Disease Models, Animal; Gene Expression Regulation; Inflammation; Lipid Peroxidation; Male; Mice; NF-E2-Related Factor 2; NF-kappa B p50 Subunit; Nitric Oxide Synthase Type II; Oxidative Stress; Phenylethyl Alcohol; Pressure Ulcer; Reactive Oxygen Species; Reperfusion Injury; Skin; Wound Healing

2018
3,4-Dihydroxyphenylethanol Assuages Cognitive Impulsivity in Alzheimer's Disease by Attuning HPA-Axis via Differential Crosstalk of α7 nAChR with MicroRNA-124 and HDAC6.
    ACS chemical neuroscience, 2018, 12-19, Volume: 9, Issue:12

    Topics: alpha Karyopherins; alpha7 Nicotinic Acetylcholine Receptor; Alzheimer Disease; Animals; Antioxidants; Corticosterone; Decision Making; Disease Models, Animal; Epigenesis, Genetic; Hippocampus; Histone Deacetylase 6; HSP90 Heat-Shock Proteins; Hypothalamo-Hypophyseal System; Impulsive Behavior; Mice; MicroRNAs; Phenylethyl Alcohol; Pituitary-Adrenal System; Receptors, Glucocorticoid

2018
Combined treatment with GSNO and CAPE accelerates functional recovery via additive antioxidant activities in a mouse model of TBI.
    Journal of neuroscience research, 2018, Volume: 96, Issue:12

    Topics: Amino Acid Oxidoreductases; AMP-Activated Protein Kinases; Animals; Antioxidants; Behavior Rating Scale; Brain Injuries, Traumatic; Caffeic Acids; Disease Models, Animal; Drug Synergism; Dynamins; GTP Phosphohydrolases; Heme Oxygenase-1; Membrane Proteins; Mice; Mice, Inbred C57BL; Mitochondria; Mitochondrial Proteins; Neurons; Neuroprotective Agents; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phenylethyl Alcohol; Protein Serine-Threonine Kinases; S-Nitrosoglutathione; Superoxide Dismutase

2018
Caffeic acid phenethyl ester (CAPE) reverses fibrosis caused by chronic colon inflammation in murine model of colitis.
    Pathology, research and practice, 2018, Volume: 214, Issue:11

    Topics: Animals; Caffeic Acids; Colitis; Colon; Disease Models, Animal; Female; Fibrosis; Inflammation; Mice; Mice, Inbred C57BL; Phenylethyl Alcohol

2018
Albumin nano-encapsulation of caffeic acid phenethyl ester and piceatannol potentiated its ability to modulate HIF and NF-kB pathways and improves therapeutic outcome in experimental colitis.
    Drug delivery and translational research, 2019, Volume: 9, Issue:1

    Topics: Albumins; Animals; Biological Availability; Caffeic Acids; Colitis; Dextran Sulfate; Disease Models, Animal; Drug Combinations; Drug Compounding; Drug Synergism; Gene Expression Regulation; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Nanoparticles; Particle Size; Phenylethyl Alcohol; Signal Transduction; Stilbenes; Transcription Factor RelA

2019
Hydroxytyrosol Exerts Anti-Inflammatory and Anti-Oxidant Activities in a Mouse Model of Systemic Inflammation.
    Molecules (Basel, Switzerland), 2018, Dec-05, Volume: 23, Issue:12

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cyclooxygenase 2; Cytokines; Disease Models, Animal; DNA Damage; Inflammation; Lipopolysaccharides; Mice; Oxidation-Reduction; Oxidative Stress; Phenylethyl Alcohol; Reactive Oxygen Species; Tumor Necrosis Factor-alpha

2018
Caffeic Acid Phenethyl Ester Rescues Pulmonary Arterial Hypertension through the Inhibition of AKT/ERK-Dependent PDGF/HIF-1α In Vitro and In Vivo.
    International journal of molecular sciences, 2019, Mar-22, Volume: 20, Issue:6

    Topics: Animals; Apoptosis; Caffeic Acids; Cell Line; Cell Proliferation; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Hemodynamics; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Phenylethyl Alcohol; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-akt; Pulmonary Artery; Rats; Signal Transduction; Vascular Remodeling

2019
Caffeic acid phenethyl ester attenuates nuclear factor‑κB‑mediated inflammatory responses in Müller cells and protects against retinal ganglion cell death.
    Molecular medicine reports, 2019, Volume: 19, Issue:6

    Topics: Animals; Astrocytes; Caffeic Acids; Cell Death; Cell Movement; Cell Nucleus; Cell Proliferation; Cell Survival; Chemokine CCL2; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Ependymoglial Cells; Glaucoma; Gliosis; In Situ Nick-End Labeling; Inflammation; Interleukin-6; Interleukin-8; Lipopolysaccharides; Male; NF-kappa B; Nitric Oxide Synthase Type II; Optic Nerve Injuries; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Retina; Retinal Ganglion Cells; Signal Transduction; Transcription Factor Brn-3A; Tumor Necrosis Factor-alpha

2019
Tyrosol Reduces Amyloid-β Oligomer Neurotoxicity and Alleviates Synaptic, Oxidative, and Cognitive Disturbances in Alzheimer's Disease Model Mice.
    Journal of Alzheimer's disease : JAD, 2019, Volume: 70, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Caspase 3; Cells, Cultured; Cognitive Dysfunction; Disease Models, Animal; Humans; Mice; Microfilament Proteins; Nerve Tissue Proteins; Neurons; Neurotoxins; Oxidative Stress; Phenylethyl Alcohol; Plant Extracts; Rhodiola

2019
Polyphenols and IUGR Pregnancies: Effects of Maternal Hydroxytyrosol Supplementation on Hepatic Fat Accretion and Energy and Fatty Acids Profile of Fetal Tissues.
    Nutrients, 2019, Jul-05, Volume: 11, Issue:7

    Topics: Adiposity; Animals; Dietary Supplements; Disease Models, Animal; Energy Metabolism; Fatty Acids; Female; Fetal Growth Retardation; Fetus; Lipid Peroxidation; Liver; Maternal Exposure; Muscle, Skeletal; Phenylethyl Alcohol; Pregnancy; Sus scrofa

2019
Effect of caffeic acid phenethyl ester on intra-abdominal adhesion in rats.
    Gynecologic and obstetric investigation, 2013, Volume: 75, Issue:4

    Topics: Abdominal Cavity; Animals; Anti-Inflammatory Agents; Antioxidants; Caffeic Acids; Disease Models, Animal; Female; Infusions, Parenteral; Laparotomy; Phenylethyl Alcohol; Rats; Tissue Adhesions; Uterus

2013
Suppression of nuclear factor erythroid 2-related factor 2 via extracellular signal-regulated kinase contributes to bleomycin-induced oxidative stress and fibrogenesis.
    Toxicology letters, 2013, Jun-20, Volume: 220, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Biomarkers; Bleomycin; Caffeic Acids; Cell Survival; Cells, Cultured; Collagen; Disease Models, Animal; Fibroblasts; Gene Silencing; Hydroxyproline; Intubation, Intratracheal; Lipid Peroxidation; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; Oxidoreductases; Phenylethyl Alcohol; Pulmonary Fibrosis; Reactive Oxygen Species

2013
Protective effects of hydroxytyrosol on liver ischemia/reperfusion injury in mice.
    Molecular nutrition & food research, 2013, Volume: 57, Issue:7

    Topics: Animals; Antioxidants; Apoptosis; Catalase; Cell Survival; Chemokine CXCL2; Disease Models, Animal; Hepatocytes; In Situ Nick-End Labeling; Interleukin-6; Liver; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Oxidative Stress; Phenylethyl Alcohol; Reactive Oxygen Species; Reperfusion Injury; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2013
Caffeic acid phenethyl ester activation of Nrf2 pathway is enhanced under oxidative state: structural analysis and potential as a pathologically targeted therapeutic agent in treatment of colonic inflammation.
    Free radical biology & medicine, 2013, Volume: 65

    Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Caffeic Acids; Cell Line, Tumor; Chromatography, High Pressure Liquid; Colitis; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Humans; Immunoprecipitation; NF-E2-Related Factor 2; Oxidative Stress; Phenylethyl Alcohol; Rats; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Structure-Activity Relationship

2013
Tyrosol exhibits negative regulatory effects on LPS response and endotoxemia.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 62

    Topics: Animals; Cells, Cultured; Cytokines; Disease Models, Animal; Endotoxemia; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Macrophages; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; NF-kappa B; Phenylethyl Alcohol; Signal Transduction; Tumor Necrosis Factor-alpha

2013
Caffeic acid phenethyl ester prevents apoptotic cell death in the developing rat brain after pentylenetetrazole-induced status epilepticus.
    Epilepsy & behavior : E&B, 2013, Volume: 29, Issue:2

    Topics: Analysis of Variance; Animals; Animals, Newborn; Apoptosis; Brain; Caffeic Acids; Caspase 3; Convulsants; Disease Models, Animal; In Situ Nick-End Labeling; Male; Neurons; Neuroprotective Agents; Pentylenetetrazole; Phenylethyl Alcohol; Rats; Rats, Wistar; Status Epilepticus

2013
The effects of melatonin and caffeic acid phenethyl ester (CAPE) on fracture healing under ischemic conditions.
    Acta orthopaedica et traumatologica turcica, 2014, Volume: 48, Issue:3

    Topics: Animals; Antioxidants; Caffeic Acids; Disease Models, Animal; Fracture Fixation, Intramedullary; Fracture Healing; Ischemia; Male; Melatonin; Phenylethyl Alcohol; Random Allocation; Rats; Rats, Wistar; Tibial Fractures

2014
The effect of caffeic acid phenethyl ester on isoproterenol-induced myocardial injury in hypertensive rats.
    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2014, Volume: 14, Issue:7

    Topics: Animals; Antioxidants; Blood Pressure; Caffeic Acids; Disease Models, Animal; Hypertension; Injections, Intraperitoneal; Isoproterenol; Lipid Peroxidation; Myocardial Infarction; Phenylethyl Alcohol; Rats

2014
3,4-dihydroxyphenylethanol attenuates spatio-cognitive deficits in an Alzheimer's disease mouse model: modulation of the molecular signals in neuronal survival-apoptotic programs.
    Neurotoxicity research, 2015, Volume: 27, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Cell Survival; Cognition Disorders; Disease Models, Animal; Hippocampus; Ibotenic Acid; Male; Mice; Mice, Inbred C57BL; Mitochondria; Neurons; Neuroprotective Agents; Peptide Fragments; Phenylethyl Alcohol; Signal Transduction

2015
Efficient immuno-modulation of TH1/TH2 biomarkers in 2,4-dinitrofluorobenzene-induced atopic dermatitis: nanocarrier-mediated transcutaneous co-delivery of anti-inflammatory and antioxidant drugs.
    PloS one, 2014, Volume: 9, Issue:11

    Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Cytokines; Dermatitis, Atopic; Dinitrofluorobenzene; Dinoprostone; Disease Models, Animal; Drug Carriers; Histamine; Hydrocortisone; Immunoglobulin E; Mice; Nanoparticles; Phenylethyl Alcohol; Skin; Th1 Cells; Th2 Cells; Vascular Endothelial Growth Factor A

2014
Suppression of skin inflammation in keratinocytes and acute/chronic disease models by caffeic acid phenethyl ester.
    Archives of dermatological research, 2015, Volume: 307, Issue:3

    Topics: Acute Disease; Animals; Caffeic Acids; Cell Line; Chronic Disease; Cyclooxygenase 2; Dermatitis, Atopic; Disease Models, Animal; Humans; Immunoglobulin E; Inflammation; Keratinocytes; Mice; Mice, Inbred Strains; NF-kappa B; Oxazolone; Phenylethyl Alcohol; Propolis; Skin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Water Loss, Insensible

2015
Inhibitory and synergistic effects of natural olive phenols on human platelet aggregation and lipid peroxidation of microsomes from vitamin E-deficient rats.
    European journal of nutrition, 2015, Volume: 54, Issue:8

    Topics: Adult; Animals; Antioxidants; Disease Models, Animal; Female; Humans; Lipid Peroxidation; Male; Methoxyhydroxyphenylglycol; Microsomes; Middle Aged; Olea; Olive Oil; Phenols; Phenylethyl Alcohol; Plant Extracts; Platelet Aggregation; Rats; Vitamin E; Vitamin E Deficiency

2015
Protective effects of hydroxytyrosol-supplemented refined olive oil in animal models of acute inflammation and rheumatoid arthritis.
    The Journal of nutritional biochemistry, 2015, Volume: 26, Issue:4

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Antioxidants; Arthritis, Rheumatoid; Cyclooxygenase 2; Dietary Supplements; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Inflammation; Male; Neutrophils; Nitric Oxide Synthase Type II; Olive Oil; Phenylethyl Alcohol; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha

2015
Caffeic acid phenethyl ester lessens disease symptoms in an experimental autoimmune uveoretinitis mouse model.
    Experimental eye research, 2015, Volume: 134

    Topics: Animals; Autoimmune Diseases; Blotting, Western; Caffeic Acids; Disease Models, Animal; Eye Proteins; Flow Cytometry; Immunoglobulin G; Interferon-gamma; Interleukin-6; Lymphocyte Activation; Mice; Mice, Inbred C57BL; NF-kappa B; Phenylethyl Alcohol; Retinitis; Retinol-Binding Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; T-Lymphocytes; Tumor Necrosis Factor-alpha; Uveitis

2015
Caffeic acid phenethyl ester abrogates bone resorption in a murine calvarial model of polyethylene particle-induced osteolysis.
    Calcified tissue international, 2015, Volume: 96, Issue:6

    Topics: Animals; Bone Resorption; Caffeic Acids; Disease Models, Animal; Female; Mice; Osteolysis; Phenylethyl Alcohol; Polyethylene; Skull; X-Ray Microtomography

2015
Value of caffeic acid phenethyl ester pretreatment in experimental sepsis model in rats.
    Mediators of inflammation, 2015, Volume: 2015

    Topics: Animals; Caffeic Acids; Disease Models, Animal; Endothelin-1; Inflammation; Male; Malondialdehyde; Oxidative Stress; Oxygen; Phenylethyl Alcohol; Random Allocation; Rats; Rats, Wistar; Sepsis; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha

2015
The effects of caffeic acid phenethyl ester (CAPE) on bacterial translocation and inflammatory response in an experimental intestinal obstruction model in rats.
    European review for medical and pharmacological sciences, 2015, Volume: 19, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Bacterial Translocation; Caffeic Acids; Disease Models, Animal; Inflammation Mediators; Injections, Intraperitoneal; Intestinal Mucosa; Intestinal Obstruction; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar

2015
3,4-dihydroxyphenylethanol suppresses irradiation-induced pulmonary fibrosis in adult rats.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cytokines; Dexamethasone; Disease Models, Animal; Heme Oxygenase-1; Humans; Lung; Male; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Phenylethyl Alcohol; Pulmonary Fibrosis; Radiation Injuries, Experimental; Rats; Rats, Sprague-Dawley

2015
Comment on 'Caffeic acid phenethyl ester lessens disease symptoms in an experimental autoimmune uveoretinitis mouse model' by Choi J.H. et al. [Exp. Eye Res. 134 (2015) 53-62].
    Experimental eye research, 2015, Volume: 138

    Topics: Animals; Autoimmune Diseases; Caffeic Acids; Disease Models, Animal; NF-kappa B; Phenylethyl Alcohol; Retinitis; Uveitis

2015
Caffeic Acid Phenethyl Ester inhibit Hepatic Fibrosis by Nitric Oxide Synthase and Cystathionine Gamma-Lyase in Rats.
    Medical science monitor : international medical journal of experimental and clinical research, 2015, Sep-17, Volume: 21

    Topics: Animals; Caffeic Acids; Cystathionine gamma-Lyase; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Hydrogen Sulfide; Immunohistochemistry; Liver; Liver Cirrhosis; Male; Nitric Oxide Synthase Type II; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley

2015
Hydroxytyrosol Protects against Myocardial Ischemia/Reperfusion Injury through a PI3K/Akt-Dependent Mechanism.
    Mediators of inflammation, 2016, Volume: 2016

    Topics: Animals; Apoptosis; Blotting, Western; Disease Models, Animal; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Oxidative Stress; Phenylethyl Alcohol; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats

2016
Hydroxytyrosol prevents metabolic impairment reducing hepatic inflammation and restoring duodenal integrity in a rat model of NAFLD.
    The Journal of nutritional biochemistry, 2016, Volume: 30

    Topics: Animals; Disease Models, Animal; Duodenum; Hepatitis; Male; Non-alcoholic Fatty Liver Disease; Phenylethyl Alcohol; Rats

2016
Oleic acid, hydroxytyrosol and n-3 fatty acids collectively modulate colitis through reduction of oxidative stress and IL-8 synthesis; in vitro and in vivo studies.
    International immunopharmacology, 2016, Volume: 35

    Topics: Animals; Caco-2 Cells; Colitis, Ulcerative; Dextran Sulfate; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Fatty Acids, Omega-3; Fish Oils; Humans; Interleukin-8; Male; Oleic Acid; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar

2016
An acetylcholine alpha7 positive allosteric modulator rescues a schizophrenia-associated brain endophenotype in the 15q13.3 microdeletion, encompassing CHRNA7.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2016, Volume: 26, Issue:7

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Brain; Brain Mapping; Cholinergic Agents; Chromosome Deletion; Chromosome Disorders; Chromosomes, Human, Pair 15; Cyclopropanes; Disease Models, Animal; Endophenotypes; Intellectual Disability; Magnetic Resonance Imaging; Male; Mice, Transgenic; Neural Pathways; Phenylethyl Alcohol; Rest; Schizophrenia; Seizures

2016
Effect of caffeic acid phenethyl ester on oxidant and anti-oxidant status of liver and serum in a rat model with acute methanol intoxication.
    Irish journal of medical science, 2017, Volume: 186, Issue:2

    Topics: Animals; Antioxidants; Caffeic Acids; Disease Models, Animal; Ethanol; Liver; Male; Methanol; Methotrexate; Oxidants; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley

2017
Hydroxytyrosol mildly improve cognitive function independent of APP processing in APP/PS1 mice.
    Molecular nutrition & food research, 2016, Volume: 60, Issue:11

    Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cognition; Diet, Mediterranean; Disease Models, Animal; Mice; Mice, Transgenic; Mitochondria; Olea; Oxidative Stress; Phenylethyl Alcohol

2016
Olive and grape seed extract prevents post-traumatic osteoarthritis damages and exhibits in vitro anti IL-1β activities before and after oral consumption.
    Scientific reports, 2016, 09-19, Volume: 6

    Topics: Administration, Oral; Animals; Anterior Cruciate Ligament; Biflavonoids; Catechin; Cyclooxygenase 2; Diet; Dinoprostone; Disease Models, Animal; Female; Grape Seed Extract; Interleukin-1beta; Male; Mass Spectrometry; Matrix Metalloproteinase 13; Metabolome; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type II; Olea; Osteoarthritis; Phenylethyl Alcohol; Proanthocyanidins; Rabbits; RNA, Messenger; Wounds and Injuries

2016
Targeting ASC in NLRP3 inflammasome by caffeic acid phenethyl ester: a novel strategy to treat acute gout.
    Scientific reports, 2016, 12-09, Volume: 6

    Topics: Administration, Oral; Animals; Biomarkers; Caffeic Acids; CARD Signaling Adaptor Proteins; Disease Models, Animal; Gout; Inflammasomes; Liquid Crystals; Macrophages; Mice; Models, Molecular; Molecular Conformation; NLR Family, Pyrin Domain-Containing 3 Protein; Phenylethyl Alcohol; Protein Binding; Uric Acid

2016
Hydroxytyrosol ameliorates metabolic, cardiovascular and liver changes in a rat model of diet-induced metabolic syndrome: Pharmacological and metabolism-based investigation.
    Pharmacological research, 2017, Volume: 117

    Topics: Animals; Biomarkers; Cardiovascular System; Diet, High-Fat; Dietary Carbohydrates; Dietary Fats; Disease Models, Animal; Liver; Male; Metabolic Syndrome; Obesity; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar

2017
The LC-MS-based metabolomics of hydroxytyrosol administration in rats reveals amelioration of the metabolic syndrome.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2017, Jan-15, Volume: 1041-1042

    Topics: Animals; Chromatography, Liquid; Disease Models, Animal; Male; Mass Spectrometry; Metabolic Networks and Pathways; Metabolic Syndrome; Metabolome; Metabolomics; Olea; Phenylethyl Alcohol; Principal Component Analysis; Rats; Rats, Wistar

2017
The effects of pollen, propolis, and caffeic acid phenethyl ester on tyrosine hydroxylase activity and total RNA levels in hypertensive rats caused by nitric oxide synthase inhibition: experimental, docking and molecular dynamic studies.
    Journal of biomolecular structure & dynamics, 2018, Volume: 36, Issue:3

    Topics: Adrenal Medulla; Animals; Caffeic Acids; Catalytic Domain; Catecholamines; Disease Models, Animal; Heart; Humans; Hypertension; Hypothalamus; Models, Molecular; Molecular Docking Simulation; Molecular Dynamics Simulation; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenylethyl Alcohol; Pollen; Propolis; Rats; Tyrosine 3-Monooxygenase

2018
Major phenolic compounds in olive oil modulate bone loss in an ovariectomy/inflammation experimental model.
    Journal of agricultural and food chemistry, 2008, Oct-22, Volume: 56, Issue:20

    Topics: Animals; Bone Density; Bone Density Conservation Agents; Disease Models, Animal; Female; Flavonoids; Humans; Inflammation; Olive Oil; Osteoporosis; Ovariectomy; Phenols; Phenylethyl Alcohol; Plant Oils; Polyphenols; Random Allocation; Rats; Rats, Wistar

2008
Akt/FOXO3a/SIRT1-mediated cardioprotection by n-tyrosol against ischemic stress in rat in vivo model of myocardial infarction: switching gears toward survival and longevity.
    Journal of agricultural and food chemistry, 2008, Oct-22, Volume: 56, Issue:20

    Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Fibrosis; Forkhead Box Protein O3; Forkhead Transcription Factors; Gene Expression; Humans; Longevity; Male; Myocardial Infarction; Myocytes, Cardiac; Phenylethyl Alcohol; Phosphorylation; Proto-Oncogene Proteins c-akt; Random Allocation; Rats; Rats, Sprague-Dawley; Sirtuin 1; Sirtuins; Survival

2008
Zinc deficiency induces vascular pro-inflammatory parameters associated with NF-kappaB and PPAR signaling.
    Journal of the American College of Nutrition, 2008, Volume: 27, Issue:5

    Topics: Animals; Atherosclerosis; Caffeic Acids; Cell Adhesion; Cells, Cultured; Cyclooxygenase 2; Disease Models, Animal; Endothelial Cells; Gene Expression Regulation; Inflammation; Male; Mice; Monocytes; NF-kappa B; Oxidative Stress; Peroxisome Proliferator-Activated Receptors; Phenylethyl Alcohol; Receptors, LDL; Rosiglitazone; Thiazolidinediones; Zinc

2008
Protective role of caffeic acid phenethyl ester and erdosteine on activities of purine-catabolizing enzymes and level of nitric oxide in red blood cells of isoniazid-administered rats.
    Toxicology and industrial health, 2008, Volume: 24, Issue:8

    Topics: Adenosine Deaminase; Administration, Oral; Animals; Antioxidants; Antitubercular Agents; Caffeic Acids; Disease Models, Animal; Drinking; Drug Therapy, Combination; Erythrocytes; Injections, Intraperitoneal; Isoniazid; Male; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Purines; Rats; Rats, Wistar; Thioglycolates; Thiophenes; Xanthine Oxidase

2008
Gingival vascular damage in atherosclerotic rabbits: hydroxytyrosol and squalene benefits.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2009, Volume: 47, Issue:9

    Topics: Animals; Antioxidants; Arteries; Atherosclerosis; Collagen; Diet, Atherogenic; Disease Models, Animal; Drug Therapy, Combination; Endothelium, Vascular; Fibrosis; Gingiva; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mouth Mucosa; Olive Oil; Periodontal Diseases; Phenylethyl Alcohol; Plant Oils; Rabbits; Squalene; Ubiquinone

2009
Therapeutic effect of caffeic acid phenethyl ester on cerulein-induced acute pancreatitis.
    World journal of gastroenterology, 2009, Nov-07, Volume: 15, Issue:41

    Topics: Acute Disease; Amylases; Animals; Caffeic Acids; Ceruletide; Cytotoxins; Disease Models, Animal; Edema; Leukocyte Count; Lipase; Male; Pancreas; Pancreatitis; Phenylethyl Alcohol; Rats; Rats, Wistar; Treatment Outcome; Tumor Necrosis Factor-alpha

2009
Protective effect of caffeic acid phenethyl ester on cyclosporine A-induced nephrotoxicity in rats.
    Renal failure, 2009, Volume: 31, Issue:9

    Topics: Animals; Antioxidants; Caffeic Acids; Cyclosporine; Disease Models, Animal; Female; Immunosuppressive Agents; Kidney; Kidney Diseases; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar

2009
Olive leaf extract attenuates cardiac, hepatic, and metabolic changes in high carbohydrate-, high fat-fed rats.
    The Journal of nutrition, 2010, Volume: 140, Issue:5

    Topics: Animals; Antioxidants; Biomarkers; Diabetes Mellitus, Experimental; Dietary Carbohydrates; Dietary Fats; Disease Models, Animal; Flavonoids; Glucose Intolerance; Heart; Hypertension; Inflammation; Liver; Male; Metabolic Syndrome; Myocardium; Obesity; Olea; Oxidative Stress; Phenols; Phenylethyl Alcohol; Phytotherapy; Plant Extracts; Plant Leaves; Polyphenols; Rats; Rats, Wistar

2010
The effects of caffeic acid phenethyl ester and melatonin on age-related vascular remodeling and cardiac damage.
    Fundamental & clinical pharmacology, 2011, Volume: 25, Issue:5

    Topics: Aging; Animals; Antioxidants; Aorta; Caffeic Acids; Catalase; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Assays; Glutathione; Heart; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Mitochondria; Myocardium; NF-kappa B; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Superoxide Dismutase

2011
Caffeic acid phenethyl ester protects against oxidative stress-related renal dysfunction in rats treated with cyclosporin A.
    Fundamental & clinical pharmacology, 2011, Volume: 25, Issue:5

    Topics: Acute Kidney Injury; Animals; Antioxidants; Blood Urea Nitrogen; Body Weight; Caffeic Acids; Creatinine; Cyclosporine; Disease Models, Animal; Drug Evaluation, Preclinical; Feeding Behavior; Glutathione; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Malondialdehyde; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Superoxide Dismutase

2011
[Antioxidant and cardioprotective effects of N-tyrosol in myocardial ischemia with reperfusion in rats].
    Kardiologiia, 2010, Volume: 50, Issue:11

    Topics: Animals; Antioxidants; Cardiotonic Agents; Coronary Vessels; Disease Models, Animal; Electrocardiography; Injections, Intravenous; Male; Myocardial Infarction; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar

2010
Protective effects of caffeic acid phenethyl ester (CAPE) on intestinal damage in necrotizing enterocolitis.
    Pediatric surgery international, 2011, Volume: 27, Issue:11

    Topics: Administration, Oral; Animals; Animals, Newborn; Apoptosis; Caffeic Acids; Caspase 9; Cell Count; Disease Models, Animal; Enterocolitis, Necrotizing; Ileum; Immunohistochemistry; In Situ Nick-End Labeling; NF-kappa B; Oxidative Stress; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Treatment Outcome; Xanthine Oxidase

2011
Stilbenes and tyrosol as target compounds in the assessment of antioxidant and hypolipidemic activity of Vitis vinifera red wines from southern Brazil.
    Journal of agricultural and food chemistry, 2011, Jul-27, Volume: 59, Issue:14

    Topics: Animals; Antioxidants; Brazil; Disease Models, Animal; Humans; Hyperlipidemias; Hypolipidemic Agents; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenylethyl Alcohol; Stilbenes; Vitis; Wine

2011
Olive oil reduces oxidative damage in a 3-nitropropionic acid-induced Huntington's disease-like rat model.
    Nutritional neuroscience, 2011, Volume: 14, Issue:3

    Topics: Administration, Oral; Animals; Antioxidants; Corpus Striatum; Disease Models, Animal; Glutathione; Huntington Disease; Injections, Intraperitoneal; Lipid Peroxidation; Male; Nitro Compounds; Olive Oil; Oxidative Stress; Phenylethyl Alcohol; Plant Oils; Propionates; Rats; Rats, Wistar; Succinate Dehydrogenase

2011
In vivo prevention of bladder urotoxicity: purified hydroxytyrosol ameliorates urotoxic effects of cyclophosphamide and buthionine sulfoximine in mice.
    International journal of toxicology, 2011, Volume: 30, Issue:4

    Topics: Animals; Antioxidants; Buthionine Sulfoximine; Catalase; Chromatography, Gas; Chromatography, High Pressure Liquid; Cyclophosphamide; Disease Models, Animal; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Industrial Waste; Lipid Peroxidation; Male; Mass Spectrometry; Mice; Olea; Phenylethyl Alcohol; Plant Extracts; Urinary Bladder; Urinary Bladder Diseases

2011
Influence of extra virgin olive oil diet enriched with hydroxytyrosol in a chronic DSS colitis model.
    European journal of nutrition, 2012, Volume: 51, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Colitis, Ulcerative; Colon; Cyclooxygenase 2; Cytokines; Dextran Sulfate; Disease Models, Animal; Down-Regulation; Female; Food, Fortified; Intestinal Mucosa; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Olive Oil; Phenylethyl Alcohol; Plant Oils; Random Allocation

2012
Neuroprotective effects of Salidroside and its analogue tyrosol galactoside against focal cerebral ischemia in vivo and H2O2-induced neurotoxicity in vitro.
    Neurotoxicity research, 2012, Volume: 21, Issue:4

    Topics: Animals; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Brain Ischemia; Cell Survival; Cerebral Cortex; Disease Models, Animal; Drug Administration Schedule; Galactosides; Glucosides; Hydrogen Peroxide; Infarction, Middle Cerebral Artery; Male; Neurons; Neuroprotective Agents; Oxidants; Phenols; Phenylethyl Alcohol; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury

2012
Caffeic Acid phenethyl ester protects blood-brain barrier integrity and reduces contusion volume in rodent models of traumatic brain injury.
    Journal of neurotrauma, 2012, Apr-10, Volume: 29, Issue:6

    Topics: Animals; Blood-Brain Barrier; Brain Injuries; Caffeic Acids; Disease Models, Animal; Fluorescent Antibody Technique; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Recovery of Function

2012
Caffeic acid phenethyl ester extends survival of a mouse model of amyotrophic lateral sclerosis.
    Neuroscience, 2012, Mar-15, Volume: 205

    Topics: Amyotrophic Lateral Sclerosis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeic Acids; Disease Models, Animal; Female; Humans; Male; Mice; Mice, Transgenic; Neuroprotective Agents; Phenylethyl Alcohol; Survival Rate; Treatment Outcome

2012
Caffeic acid phenethyl ester protects nigral dopaminergic neurons via dual mechanisms involving haem oxygenase-1 and brain-derived neurotrophic factor.
    British journal of pharmacology, 2012, Volume: 166, Issue:3

    Topics: Animals; Blotting, Western; Brain-Derived Neurotrophic Factor; Caffeic Acids; Disease Models, Animal; Dopaminergic Neurons; Enzyme Induction; Heme Oxygenase-1; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Nitric Oxide; Parkinsonian Disorders; Phenylethyl Alcohol; Rats; Rats, Wistar; Substantia Nigra

2012
Cancer prevention mediated by caffeic acid phenethyl ester involves cyp2b1/2 modulation in hepatocarcinogenesis.
    Toxicologic pathology, 2012, Volume: 40, Issue:3

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Caffeic Acids; Carcinogenicity Tests; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2B1; Cytochromes; Diethylnitrosamine; Disease Models, Animal; Liver Neoplasms, Experimental; Male; Phenylethyl Alcohol; Proadifen; Rats; Rats, Inbred F344; Steroid Hydroxylases

2012
Alperujo extract, hydroxytyrosol, and 3,4-dihydroxyphenylglycol are bioavailable and have antioxidant properties in vitamin E-deficient rats--a proteomics and network analysis approach.
    Molecular nutrition & food research, 2012, Volume: 56, Issue:7

    Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Anticholesteremic Agents; Antioxidants; Diet; Dietary Supplements; Disease Models, Animal; Food-Processing Industry; Fruit; Hypolipidemic Agents; Industrial Waste; Intestinal Absorption; Liver; Male; Methoxyhydroxyphenylglycol; Mitochondrial Proteins; Olea; Oxidative Stress; Phenylethyl Alcohol; Plant Extracts; Random Allocation; Rats; Vitamin E Deficiency

2012
Caffeic acid phenethyl ester effects in the kidney during ischemia and reperfusion in rats anesthetized with isoflurane.
    Transplantation proceedings, 2012, Volume: 44, Issue:5

    Topics: Anesthetics, Inhalation; Animals; Biomarkers; Caffeic Acids; Creatinine; Disease Models, Animal; Isoflurane; Kidney; Male; Necrosis; Phenylethyl Alcohol; Rats; Rats, Wistar; Reperfusion Injury; Time Factors

2012
Caffeic acid phenethyl ester protects kidneys against acetylsalicylic acid toxicity in rats.
    Renal failure, 2012, Volume: 34, Issue:9

    Topics: Acute Kidney Injury; Animals; Aspirin; Caffeic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Kidney; NF-kappa B; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar

2012
Comparative analysis of the protective effects of caffeic acid phenethyl ester (CAPE) on pulmonary contusion lung oxidative stress and serum copper and zinc levels in experimental rat model.
    Biological trace element research, 2013, Volume: 151, Issue:1

    Topics: Analysis of Variance; Animals; Blood Gas Analysis; Caffeic Acids; Catalase; Contusions; Copper; Disease Models, Animal; Humans; Lung; Male; Malondialdehyde; Oxidative Stress; Phenylethyl Alcohol; Protective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Zinc

2013
Effects of caffeic acid phenethyl ester on anastomotic healing in secondary peritonitis.
    Journal of investigative surgery : the official journal of the Academy of Surgical Research, 2012, Volume: 25, Issue:5

    Topics: Anastomosis, Surgical; Animals; Caffeic Acids; Colon; Disease Models, Animal; Glutathione; Hydroxyproline; Male; Malondialdehyde; Peritonitis; Peroxidase; Phenylethyl Alcohol; Pressure; Rats; Rats, Wistar; Stress, Mechanical; Superoxide Dismutase; Wound Healing

2012
Suppression of Toll-like receptor 4 activation by caffeic acid phenethyl ester is mediated by interference of LPS binding to MD2.
    British journal of pharmacology, 2013, Volume: 168, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Caffeic Acids; Cell Line; Chromatography, Gas; Disease Models, Animal; Gene Expression Regulation; HEK293 Cells; Humans; Inflammation; Interferon Regulatory Factor-3; Lipopolysaccharides; Lymphocyte Antigen 96; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; NF-kappa B; Phenylethyl Alcohol; Signal Transduction; Tandem Mass Spectrometry; Toll-Like Receptor 4

2013
Caffeic acid phenethyl ester protects against the dopaminergic neuronal loss induced by 6-hydroxydopamine in rats.
    Neuroscience, 2013, Mar-13, Volume: 233

    Topics: Adrenergic Agents; Animals; Antioxidants; Caffeic Acids; Cell Death; Disease Models, Animal; Dopaminergic Neurons; Free Radical Scavengers; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders; Phenylethyl Alcohol; Rats; Rats, Wistar

2013
Self-assembled polymeric nanoparticles for percutaneous co-delivery of hydrocortisone/hydroxytyrosol: an ex vivo and in vivo study using an NC/Nga mouse model.
    International journal of pharmaceutics, 2013, Feb-28, Volume: 444, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents; Chitosan; Dermatitis, Atopic; Dinitrofluorobenzene; Disease Models, Animal; Drug Carriers; Hydrocortisone; Mice; Nanoparticles; Phenylethyl Alcohol; Skin; Skin Absorption

2013
The protective role of caffeic acid phenethyl ester (CAPE) on testicular tissue after testicular torsion and detorsion.
    World journal of urology, 2002, Volume: 20, Issue:4

    Topics: Animals; Caffeic Acids; Catalase; Disease Models, Animal; Glutathione Peroxidase; Male; Peroxidase; Phenylethyl Alcohol; Protective Agents; Rats; Reperfusion Injury; Spermatic Cord Torsion; Superoxide Dismutase; Testis; Thiobarbituric Acid Reactive Substances

2002
Effect of caffeic acid phenethyl ester on cartilage in experimental osteoarthritis.
    Rheumatology international, 2002, Volume: 22, Issue:6

    Topics: Animals; Anterior Cruciate Ligament; Anterior Cruciate Ligament Injuries; Caffeic Acids; Cartilage, Articular; Disease Models, Animal; Disease Progression; Extracellular Matrix; Hindlimb; Injections, Intra-Articular; NF-kappa B; Osteoarthritis, Knee; Phenylethyl Alcohol; Proteoglycans; Rabbits

2002
Caffeic acid phenethyl ester (CAPE) prevents inflammatory stress in organotypic hippocampal slice cultures.
    Brain research. Molecular brain research, 2003, Jul-23, Volume: 115, Issue:2

    Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Antioxidants; Caenorhabditis elegans Proteins; Caffeic Acids; Cell Nucleus; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electrophoretic Mobility Shift Assay; Hippocampus; Immunohistochemistry; Inflammation; Interferon-gamma; Lipopolysaccharides; NF-kappa B; Nitrites; Organ Culture Techniques; Phenylethyl Alcohol; Rats; Rats, Wistar; Stress, Physiological; Tumor Necrosis Factor-alpha

2003
3,4-Dihydroxyphenylacetaldehyde is the toxic dopamine metabolite in vivo: implications for Parkinson's disease pathogenesis.
    Brain research, 2003, Nov-07, Volume: 989, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Glial Fibrillary Acidic Protein; Homovanillic Acid; Immunohistochemistry; Male; Neurons; Parkinson Disease; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase; Ventral Tegmental Area

2003
Chemoprotective effect of caffeic acid phenethyl ester on promotion in a medium-term rat hepatocarcinogenesis assay.
    International journal of cancer, 2004, Feb-10, Volume: 108, Issue:4

    Topics: Animals; Blotting, Western; Caffeic Acids; Carcinoma, Hepatocellular; Cell Nucleus; Disease Models, Animal; Disease Progression; gamma-Glutamyltransferase; Gene Expression Regulation; Glutathione S-Transferase pi; Glutathione Transferase; Humans; I-kappa B Proteins; Isoenzymes; Liver Neoplasms, Experimental; Male; NF-kappa B; NF-KappaB Inhibitor alpha; Phenylethyl Alcohol; Precancerous Conditions; Protein Transport; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2004
Protective effects of caffeic acid phenethyl ester against experimental allergic encephalomyelitis-induced oxidative stress in rats.
    Free radical biology & medicine, 2004, Aug-01, Volume: 37, Issue:3

    Topics: Animals; Biomarkers; Brain; Caffeic Acids; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Oxidative Stress; Phenylethyl Alcohol; Protective Agents; Rats; Rats, Wistar; Spinal Cord

2004
Caffeic acid phenethyl ester ameliorated ototoxicity induced by cisplatin in rats.
    Journal of chemotherapy (Florence, Italy), 2004, Volume: 16, Issue:4

    Topics: Analysis of Variance; Animals; Caffeic Acids; Cisplatin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Female; Hearing Loss, Sensorineural; Otoacoustic Emissions, Spontaneous; Phenylethyl Alcohol; Probability; Random Allocation; Rats; Rats, Wistar; Reference Values; Sensitivity and Specificity; Statistics, Nonparametric

2004
Caffeic acid phenethyl ester improves oxidative organ damage in rat model of thermal trauma.
    Physiological research, 2004, Volume: 53, Issue:6

    Topics: Animals; Burns; Caffeic Acids; Disease Models, Animal; Injections, Intraperitoneal; Kidney Diseases; Lung Diseases; Male; Malondialdehyde; Multiple Organ Failure; Oxidoreductases; Phenylethyl Alcohol; Rats; Rats, Wistar; Treatment Outcome

2004
[Xanthine oxidase inhibitory activity and hypouricemia effect of propolis in rats].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2005, Volume: 125, Issue:3

    Topics: Animals; Anti-Infective Agents; Brazil; Caffeic Acids; China; Coumaric Acids; Disease Models, Animal; Flavonoids; Gout; Hyperuricemia; Male; Oxonic Acid; Phenylethyl Alcohol; Phenylpropionates; Propionates; Propolis; Rats; Rats, Sprague-Dawley; Uric Acid; Xanthine Oxidase

2005
Effects of caffeic acid phenethyl ester on endotoxin-induced uveitis in rats.
    Current eye research, 2005, Volume: 30, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Aqueous Humor; Caffeic Acids; Ciliary Body; Disease Models, Animal; Eye Proteins; Injections, Intraperitoneal; Iris; Lipopolysaccharides; Male; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Wistar; Salmonella typhimurium; Uveitis

2005
In vivo effects of caffeic acid phenethyl ester on myocardial ischemia-reperfusion injury and apoptotic changes in rats.
    Annals of clinical and laboratory science, 2005,Autumn, Volume: 35, Issue:4

    Topics: Animals; Antioxidants; Apoptosis; Aspartate Aminotransferases; Caffeic Acids; Cell Count; Coronary Disease; Creatine Kinase; Disease Models, Animal; Glutathione; In Situ Nick-End Labeling; Lipid Peroxidation; Male; Myocardial Reperfusion Injury; Nitric Oxide; Phenylethyl Alcohol; Rats; Rats, Wistar

2005
Caffeic acid phenethyl ester ameliorates cerebral infarction in rats subjected to focal cerebral ischemia.
    Life sciences, 2006, May-01, Volume: 78, Issue:23

    Topics: Animals; Antioxidants; Blood Flow Velocity; Brain; Brain Ischemia; Caffeic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Nitric Oxide; Phenylethyl Alcohol; Rats; Rats, Long-Evans; Reperfusion Injury

2006
Role of vagal activity on bradicardic and hypotensive effects of caffeic acid phenethyl ester (CAPE).
    Cardiovascular toxicology, 2005,Fall, Volume: 5, Issue:4

    Topics: Animals; Antihypertensive Agents; Atropine; Blood Pressure; Bradycardia; Caffeic Acids; Disease Models, Animal; Male; Muscarinic Antagonists; Parasympathetic Nervous System; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Vagotomy; Vagus Nerve

2005
Black Lucques olives prevented bone loss caused by ovariectomy and talc granulomatosis in rats.
    The British journal of nutrition, 2007, Volume: 97, Issue:5

    Topics: Animals; Antioxidants; Body Weight; Bone Density; Calcium; Disease Models, Animal; Female; Fruit; Humans; Inflammation; Olea; Organ Size; Osteoporosis; Osteoporosis, Postmenopausal; Ovariectomy; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Talc; Uterus; Vitamin E

2007
Caffeic acid phenethyl ester reduces neurovascular inflammation and protects rat brain following transient focal cerebral ischemia.
    Journal of neurochemistry, 2007, Volume: 102, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Biomarkers; Caffeic Acids; Cerebrovascular Circulation; Disease Models, Animal; Dose-Response Relationship, Drug; Encephalitis; Inflammation Mediators; Ischemic Attack, Transient; Male; Neuroprotective Agents; NF-kappa B; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Treatment Outcome

2007
Protective effects of caffeic acid phenethyl ester, vitamin C, vitamin E and N-acetylcysteine on vancomycin-induced nephrotoxicity in rats.
    Basic & clinical pharmacology & toxicology, 2007, Volume: 100, Issue:5

    Topics: Acetylcysteine; Animals; Anti-Bacterial Agents; Antioxidants; Ascorbic Acid; Blood Urea Nitrogen; Caffeic Acids; Catalase; Disease Models, Animal; Drinking; Drug Combinations; Injections, Intramuscular; Injections, Intraperitoneal; Kidney; Kidney Diseases; Male; Phenylethyl Alcohol; Rats; Rats, Wistar; Vancomycin; Vitamin E; Water Supply

2007
Effect of caffeic acid phenethyl ester on the regression of endometrial explants in an experimental rat model.
    Reproductive sciences (Thousand Oaks, Calif.), 2007, Volume: 14, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Caffeic Acids; Catalase; Cyclooxygenase 2; Disease Models, Animal; Endometriosis; Endometrium; Female; Lipid Peroxidation; Malondialdehyde; Phenylethyl Alcohol; Rats; Rats, Wistar; Statistics, Nonparametric; Superoxide Dismutase; Transplantation, Autologous; Uterus

2007
Evaluation of anti-allergic properties of caffeic acid phenethyl ester in a murine model of systemic anaphylaxis.
    Toxicology and applied pharmacology, 2008, Jan-01, Volume: 226, Issue:1

    Topics: Anaphylaxis; Animals; Anti-Allergic Agents; Caffeic Acids; Disease Models, Animal; Female; Histamine Release; Immunoglobulin E; Mice; Mice, Inbred ICR; NF-kappa B; Ovalbumin; Phenylethyl Alcohol; Tumor Necrosis Factor-alpha

2008
Caffeic acid phenethyl ester accelerates cutaneous wound healing in a rat model and decreases oxidative stress.
    Clinical and experimental dermatology, 2007, Volume: 32, Issue:6

    Topics: Animals; Antioxidants; Caffeic Acids; Disease Models, Animal; Drug Evaluation, Preclinical; Free Radical Scavengers; Glutathione; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Reactive Oxygen Species; Skin; Superoxide Dismutase; Wound Healing

2007
Effects of caffeic acid phenethyl ester on pancreatitis in rats.
    The Journal of surgical research, 2008, Volume: 145, Issue:1

    Topics: Alanine Transaminase; Animals; Antioxidants; Bacterial Translocation; Bronchoalveolar Lavage Fluid; Caffeic Acids; Detergents; Disease Models, Animal; Glycodeoxycholic Acid; L-Lactate Dehydrogenase; Lung; Male; Malondialdehyde; Pancreas; Pancreatitis, Acute Necrotizing; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley

2008
Comparative study of Rhodiola preparations on behavioral despair of rats.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2008, Volume: 15, Issue:1-2

    Topics: Administration, Oral; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Depression; Disaccharides; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Glucosides; Male; Molecular Structure; Phenols; Phenylethyl Alcohol; Piper nigrum; Plant Preparations; Plant Roots; Rats; Rats, Wistar; Rhodiola; Stress, Physiological

2008
In vivo effect of the natural antioxidant hydroxytyrosol on cyclosporine nephrotoxicity in rats.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008, Volume: 23, Issue:4

    Topics: Animals; Antioxidants; Aorta, Abdominal; Cyclosporine; Disease Models, Animal; Ethidium; Gene Expression; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Glutathione; Heme Oxygenase-1; Immunosuppressive Agents; Kidney Glomerulus; Lipid Peroxidation; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA; Thiobarbituric Acid Reactive Substances; Treatment Outcome

2008
Caffeic acid phenethyl ester attenuates allergic airway inflammation and hyperresponsiveness in murine model of ovalbumin-induced asthma.
    Life sciences, 2008, Mar-26, Volume: 82, Issue:13-14

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Blotting, Western; Bronchoalveolar Lavage Fluid; Caffeic Acids; Cell Count; Cytokines; Disease Models, Animal; Eosinophils; Female; Immunoglobulin E; Lung; Mice; Mice, Inbred BALB C; NF-kappa B; Ovalbumin; Peroxides; Phenylethyl Alcohol; Respiratory Hypersensitivity

2008
The effects of caffeic acid phenethyl ester (CAPE) on spinal cord ischemia/reperfusion injury in rabbits.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 1999, Volume: 16, Issue:4

    Topics: Animals; Antioxidants; Caffeic Acids; Catalase; Disease Models, Animal; Drug Therapy, Combination; Injections, Intraperitoneal; Malondialdehyde; Methylprednisolone; Movement; Neuroprotective Agents; NF-kappa B; Phenylethyl Alcohol; Rabbits; Reperfusion Injury; Spinal Cord; Spinal Cord Ischemia; Superoxide Dismutase

1999
Caffeic acid phenethyl ester, an inhibitor of nuclear factor-kappaB, attenuates bacterial peptidoglycan polysaccharide-induced colitis in rats.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:3

    Topics: Animals; Apoptosis; Arthritis; Caffeic Acids; Cells, Cultured; Colitis; Colon; Cytokines; Disease Models, Animal; Female; Humans; NF-kappa B; Peptidoglycan; Phenylethyl Alcohol; Rats; Rats, Inbred Lew

2001