phenylephrine-hydrochloride and Venous-Thrombosis

Topics: Aged; Antigens, Fungal; Asthma; Blastomyces; Blastomycosis; Carcinoma, Squamous Cell; Delayed Diagnosis; Diagnosis, Differential; Dyspnea; Glucocorticoids; Humans; Lung; Male; Nose; Nose Neoplasms; Pulmonary Embolism; Radiography; Venous Thrombosis

The successful harvest and transplant of a fibular flap depends on many factors, including healthy inflow and outflow systems. A contraindication to harvesting a fibular flap is disease of the lower extremity arterial system; therefore, preoperative evaluation of the arterial system is routine. Preoperative evaluation of the venous system is not routine, unless there is clinical suspicion of venous disease.. Retrospective chart review.. Two cases of occult deep venous thrombosis (DVT) were encountered intraoperatively resulting in nontransplantable flaps.. This finding represents a serious concern, and we believe that venous imaging should be considered in patients with significant risk factors for harboring an occult DVT. Laryngoscope, 2009.

Topics: Adult; Bone Transplantation; Female; Humans; Intraoperative Complications; Magnetic Resonance Angiography; Male; Mandibular Injuries; Maxilla; Melanoma; Middle Aged; Nose; Palatal Neoplasms; Reoperation; Suicide, Attempted; Surgical Flaps; Tissue and Organ Harvesting; Ultrasonography, Doppler; Venous Thrombosis; Wounds, Gunshot

Acrodysostosis is a rare syndrome characterized by peripheral dysostosis, nasal hypoplasia and frequently mental retardation. Only one adult case of acrodysostosis has been reported to have neurologic symptoms. We report one further adult case of acrodysostosis with severe neurologic findings including myelopathy and spastic paraparesis due to diffuse spinal stenosis and recurrent deep vein thrombosis possibly caused by neurologic deficits.. We report a 43-year-old woman who had back and neck pain with weakness in the extremities of several years. 1~year before admission to our hospital, she had been treated with a missed diagnosis of sero (-) spondyloarthropathy but had not benefited. She became unable to walk, thereafter she underwent decompression surgery with a diagnosis of degenerative spinal stenosis. She presented at our outpatient department complaining of lowback pain and difficulty walking. She had marked facial and peripheral appearance of acrodysostosis. Spinal MRI revealed extensive spinal stenosis. A diagnosis was made through the genetic investigation, clinical and radiological findings. Spastic paraparesis were detected. There was widespread neuropathic pain. 15 days after admission, she developed swelling and redness of the left lower extremity and the venous doppler ultrasonography showed left acute and right past DVT. We treated DVT with anticoagulant therapy. Gabapentin and Baclofen were initiated for neuropathic pain and spasticity. A conventional rehabilitation program was performed. She left walking with a walker without pain and spasticity.. We would like to remind physicians to be aware of peripheral malformations as signs of skeletal dysplasias and to consider acrodysostosis in the differential diagnosis. Although it is a rare condition, if diagnosed early, possible complications can be treated and outcomes may be improved.

Topics: Adult; Anticoagulants; Dysostoses; Female; Hand Deformities, Congenital; Humans; Intellectual Disability; Nose; Paraparesis, Spastic; Spinal Stenosis; Syndrome; Venous Thrombosis

We were presented with a teenage female who developed superior ophthalmic vein thrombosis and cavernous sinus thrombophlebitis after a 1-week history of a single acne-like lesion or furuncle at the anterior tip of the nose. She was managed aggressively with heparin and intravenous antibiotic. Signs and symptoms improved after 2 weeks of treatment, and she was discharged with an anticoagulant.

Topics: Adolescent; Anticoagulants; Cavernous Sinus Thrombosis; Cloxacillin; Disease Progression; Eye; Female; Follow-Up Studies; Furunculosis; Heparin; Humans; Nose; Risk Assessment; Severity of Illness Index; Staphylococcal Infections; Tomography, X-Ray Computed; Treatment Outcome; Veins; Venous Thrombosis

Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticoagulants; Bone Transplantation; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Male; Maxillofacial Development; Nose; Postoperative Complications; Pregnancy; Pregnancy Complications, Cardiovascular; Reoperation; Rhinoplasty; Thrombophlebitis; Treatment Outcome; Venous Thrombosis; Warfarin

Topics: Animals; Eye; Furunculosis; Humans; Nose; Retinal Vessels; Surgical Procedures, Operative; Thrombophlebitis; Veins; Venous Thrombosis