phenylephrine-hydrochloride and Takayasu-Arteritis

Aortitis and saddle nose deformity are extremely unusual manifestations of a variety of systemic diseases. The concurrent appearance of these apparently disparate clinical features is a clinical rarity. A case of saddle nose deformity in a patient with confirmed Takayasu's arteritis is presented. The relevant literature is reviewed with reference to the possible differential diagnosis of patients with aortitis and saddle nose deformity.

Topics: Adult; Aorta, Thoracic; Aortic Valve Stenosis; Diagnosis, Differential; Female; Humans; Magnetic Resonance Angiography; Nose; Nose Deformities, Acquired; Takayasu Arteritis; Tomography, X-Ray Computed

Wegener's granulomatosis and forms of giant cell arteritis result from vasculitis and masquerade with symptoms of common head and neck disease entities. Recognition of the manifestations of vasculitis can be made early in the disease course and confirmed pathologically, allowing effective therapy. Current therapy of Wegener's granulomatosis with Cytoxin and Imuran and steroids for giant cell arteritis frequently results in reversal of head and neck involvement, prevention of systemic disease, and prolonged survival.

Topics: Aortic Arch Syndromes; Diagnosis, Differential; Eye; Female; Giant Cell Arteritis; Granulomatosis with Polyangiitis; Head; Humans; Middle Aged; Mouth Mucosa; Neck; Nose; Paranasal Sinuses; Takayasu Arteritis