phenylephrine-hydrochloride and Sarcoidosis

Topics: Biopsy; Drug Therapy, Combination; Female; Humans; Middle Aged; Nose; Sarcoidosis; Skin; Skin Diseases; Vulva; Vulvar Diseases

Topics: Acne Vulgaris; Adult; Carcinoma, Basal Cell; Dermatitis; Diagnosis, Differential; Erythema; Exanthema; Eye Manifestations; Female; Humans; Lupus Vulgaris; Male; Middle Aged; Nose; Rosacea; Sarcoidosis; Skin Neoplasms; Telangiectasis

Topics: Blood Protein Electrophoresis; Cilia; Diagnosis, Differential; Granuloma; Granuloma, Lethal Midline; Granulomatosis with Polyangiitis; Herpes Simplex; Humans; Kidney Transplantation; Leishmaniasis, Mucocutaneous; Leprosy; Lysosomes; Microscopy, Electron; Mycoses; Nasal Polyps; Nose; Postoperative Complications; Prognosis; Respiratory Tract Diseases; Rhinitis; Rhinoscleroma; Sarcoidosis; Syphilis; Transplantation, Homologous; Tuberculosis; Tuberculosis, Laryngeal

A 42-year-old man with no relevant medical history presented with a painless, red, disfiguring skin lesion located on the nose. He was diagnosed with lupus pernio, a rare, cutaneous subtype of sarcoidosis which is relatively resistant to therapy and is associated with systemic sarcoidosis.

Topics: Adult; Humans; Male; Nose; Nose Diseases; Sarcoidosis; Skin; Skin Diseases

In addition to its mucosal pathology, sarcoidosis of the nose may cause a range of skin abnormalities and destruction of the osteocartilaginous structures of the nose. Clinical presentation can mimic other diseases and a biopsy is often necessary. We propose a classification of nasal sarcoidosis based on disease location to help with recognition of the symptoms and, subsequently, treatment. Here we describe 4 patients with nasal sarcoidosis. In the first patient, a 53-year-old woman with a granuloma in the nasal vestibule, the lesion was excised. The second patient, a 38-year-old man with intranasal crusts, synechiae and atrophic mucosa, was treated with corticosteroid nasal drops. The third and fourth patients, a 36-year-old man with progressive widening of the nasal dorsum and a 60-year-old woman with a saddle nose, respectively, were treated with a rhinoplasty.

Topics: Adrenal Cortex Hormones; Adult; Biopsy; Female; Humans; Male; Middle Aged; Nose; Nose Diseases; Practice Guidelines as Topic; Rhinoplasty; Sarcoidosis

Topics: Aged, 80 and over; Cheek; Diagnosis, Differential; Facial Dermatoses; Female; Forearm; Humans; Lichenoid Eruptions; Nose; Sarcoidosis

Topics: Adult; Biopsy; Diagnosis, Differential; Female; Humans; Nose; Sarcoidosis; Skin

Sarcoidosis is a multisystem inflammatory disease that manifests as noncaseating granulomas, commonly in the lungs and intrathoracic lymph nodes. Subcutaneous manifestations of sarcoidosis that are caused by granulomas are referred to as specific for sarcoidosis, whereas other lesions are considered nonspecific. The authors present "sarcoidosis nodule formation on the lateral nasal osteotomy lines" in a sarcoidosis patient undergoing rhinoplasty surgery as a rare patient.. V.

Topics: Adult; Female; Humans; Lymph Nodes; Magnetic Resonance Imaging; Nose; Nose Diseases; Osteotomy; Reoperation; Rhinoplasty; Sarcoidosis; Tomography, X-Ray Computed

Topics: Adult; Facial Dermatoses; Humans; Lymph Nodes; Lymphatic Diseases; Male; Nose; Nose Diseases; Recurrence; Sarcoidosis; Stomach Diseases

Our patient sought treatment for the nodules on his nose, but the nodules on his tattoos proved particularly helpful in making the diagnosis.

Topics: Adrenal Cortex Hormones; Adult; Biopsy; Diagnosis, Differential; Humans; Male; Nose; Sarcoidosis; Tattooing

An 80 year old female patient was seen in the Otolaryngology department with a skin manifestation of her sarcoidosis, known as lupus pernio. Around 25% of patients with sarcoidosis have skin disease and the presence of lupus pernio may suggest a more aggressive form of the disease. Photography of this relatively rare presentation not only helped us diagnose her underlying medical condition but also served as a baseline during treatment.

Topics: Aged, 80 and over; Female; Humans; Nose; Photography; Sarcoidosis

Coccidioides immitis, a pathogenic fungus endemic to arid regions, is the etiologic agent of cutaneous coccidioidomycosis. Primary cutaneous coccidioidomycosis is rare. The majority of cutaneous coccidioidomycosis infections are caused by dissemination of the fungus from the lungs to the skin. Diagnosing cutaneous coccidioidomycosis often can be difficult because it can mimic a variety of other clinical conditions. We present a case of a 45-year-old man presenting with cutaneous coccidioidomycosis on the tip of his nose. This patient had pulmonary symptoms in addition to his cutaneous findings, leading to a diagnosis of disseminated coccidioidomycosis.

Topics: Antifungal Agents; Coccidioidomycosis; Dermatomycoses; Fluconazole; Follow-Up Studies; Humans; Lung Diseases, Fungal; Male; Middle Aged; Nose; Sarcoidosis

Topics: Diagnosis, Differential; Facial Dermatoses; Female; Humans; Middle Aged; Nose; Sarcoidosis

A 54-year-old man presented with symmetric, bulbous, nodular enlargement of his nasal tip and ala. At first inspection, the changes appeared to be consistent with rhinophyma, but biopsy revealed noncaseating granulomata consistent with sarcoidosis. His laboratory, radiographic, and functional studies were consistent with systemic involvement of his disease.

Topics: Diagnosis, Differential; Humans; Male; Middle Aged; Nose; Rhinophyma; Sarcoidosis

Urologic involvement in sarcoidosis is rare. We report a patient who presented with a testicular mass and, shortly thereafter, manifested nasal lesions of the papular variant of cutaneous sarcoidosis. Histologic examination from both organ systems yielded sarcoidal granulomas. The patient was successfully treated using oral corticosteroids. Sarcoidosis continues to replace syphilis as "the great imitator of the 1990s," and clinicians must be increasingly aware of its variable presentations.

Topics: Adrenal Cortex Hormones; Adult; Diagnosis, Differential; Epididymis; Granuloma; Humans; Male; Nose; Sarcoidosis; Testicular Diseases; Testicular Neoplasms; Testis

We report a patient with massive facial sarcoidosis. While skin involvement is a common manifestation of sarcoidosis, it is unusual to see it in the dramatic form of cutaneous tumors with mutilation of the central face. There are few reports of tumoral cutaneous sarcoidosis like that of our patient.

Topics: Adult; Facial Dermatoses; Female; Humans; Nose; Orbital Neoplasms; Sarcoidosis; Skin Neoplasms

A female patient from Morocco developed chronic sarcoidosis with destruction of two interphalangeal joints.

Topics: Female; Finger Joint; Fingers; Humans; Isoniazid; Middle Aged; Nose; Prednisone; Pyridoxine; Sarcoidosis; Skin; Tuberculosis

A series of 19 cases has been reviewed in which biopsy of an intra-nasal lesion revealed a granulomatous pathology. These have been classified on an aetiological basis. They include infections, Wegener's granuloma and neoplasms with a granulomatous stroma. One patient with sarcoidosis first presented with lesions in the nasal cavity. Cholesterol granulomata were seen in four lesions removed from the paranasal sinuses. In six cases clinical and histological examination failed to show a cause for the granulomata; in all of these patients the nasal cavity was free from disease at a subsequent examination.

Topics: Adult; Aged; Biopsy; Cholesterol; Female; Granuloma; Granulomatosis with Polyangiitis; Humans; Leprosy; Male; Middle Aged; Nose; Nose Diseases; Nose Neoplasms; Sarcoidosis; Tuberculosis

The nasal and aural temperature patterns of 100 normal subjects have been investigated by infrared thermography, paying particular attention to possible errors of instrumentation and technique which may arise in such areas of complex morphology. Although by no means invariable, the pattern of themograms confirms that certain areas which are relatively cool are often affected in lepromatous leprosy, tuberculosis, leishmaniasis, and lupus pernio. In lepromatous leprosy, low temperature appears to govern the localization of disease in most parts of the body, and the possible reasons for this are discussed. Thermography may have a place in the investigation of other skin diseases in which the distribution of lesions on the body surface is unexplained.

Topics: Adult; Aged; Child; Ear; Female; Humans; Leishmaniasis; Leprosy; Male; Middle Aged; Nose; Sarcoidosis; Thermography; Tuberculosis, Cutaneous

Nasal sarcoidosis may affect nasal skin, mucosa, or bone separately or simulataneously. Its incidence in patients with systemic sarcoid was once thought to be low, but this may be due to lack of proper intranasal examination and awareness of its existence by physicians who are more preoccupied with lung and other visceral involvement. The otolaryngologist should be aware of nasal sarcoidosis because nasal obstruction or drainage secondary to nasal sarcoidosis may be the first and only manifestation of systemic sarcoidosis. The otolaryngologist can diagnose this disease earlier in its course by being aware of its existence.

Topics: Administration, Topical; Adult; Diagnosis, Differential; Female; Humans; Male; Nose; Nose Diseases; Prednisone; Sarcoidosis; Triamcinolone Acetonide

Topics: Adult; Biopsy; Diagnosis, Differential; Female; Humans; Middle Aged; Nose; Radiography; Sarcoidosis; Tuberculosis, Cutaneous

Topics: Humans; Nasal Bone; Nose; Radiography; Sarcoidosis

Topics: Adrenal Cortex Hormones; Humans; Larynx; Mucous Membrane; Nasal Mucosa; Nose; Pharynx; Rhinitis; Rhinitis, Atrophic; Sarcoidosis

Topics: Nose; Sarcoidosis

Topics: Humans; Nasopharynx; Nose; Pharynx; Sarcoidosis

Topics: Disease; Humans; Nasal Cavity; Nose; Nose Diseases; Sarcoidosis; Trachea

Topics: Humans; Neck; Nose; Pharynx; Sarcoidosis; Staining and Labeling

Topics: Humans; Larynx; Nose; Sarcoidosis; Trachea

Topics: Humans; Neoplasms; Nose; Nose Neoplasms; Sarcoidosis

Topics: Nose; Nose Diseases; Sarcoidosis