phenylephrine-hydrochloride and Rhinosporidiosis

Rhinosporidiosis is a chronic mucocutaneous granulomatous disease caused by

Topics: Adult; Animals; Bronchi; Humans; Male; Nasal Obstruction; Nose; Rhinosporidiosis; Rhinosporidium

Rhinosporidiosis is a chronic fungal inflammatory disease prevalent in India and Sri Lanka. Its manifestations are mostly nasal and extranasal lesions are relatively rare. Occasional atypical presentations of this disease lead to diagnostic dilemma. Herein we report on a case of nasopharyngeal rhinosporidiosis having extensive involvement of paranasal sinuses along with intracranial extension which mimicked radiologically as juvenile nasopharyngeal angiofibroma. To our knowledge, this is the first reported case of rhinosporidiosis having intracranial extension. We discuss the pathology, treatment and briefly review the literature of this rare disease.

Topics: Angiofibroma; Animals; Head and Neck Neoplasms; Humans; Nose; Rhinosporidiosis; Rhinosporidium

Rhinosporidiosis is a chronic mucocutaneous granulomatous disease caused by

Topics: Adult; Animals; Endoscopy; Humans; Male; Nasolacrimal Duct; Nose; Rhinosporidiosis; Rhinosporidium

To study the clinical profile and the route of spread of lacrimal sac rhinosporidiosis. To device a standard transnasal endoscopic surgical procedure in the treatment of lacrimal sac rhinosporidiosis.. This is a retrospective analysis of a case series on lacrimal sac rhinosporidiosis. Thirteen cases of lacrimal sac rhinosporidiosis reported in our institution from July 2003 to July 2016 were included. Workup included diagnostic nasal endoscopy and lacrimal syringing. All patients underwent transnasal endoscopic excision of rhinosporidiosis.. Lacrimal sac rhinosporidiosis was more prevalent among males and in the 31 to 40 years age group. All patients had a history of bathing in stagnant water bodies. The most common clinical presentation was a doughy swelling medial to the medial canthus. Lacrimal sac rhinosporidiosis invariably presented with involvement of the nasolacrimal duct. Following the endoscopic excision of lacrimal sac rhinosporidiosis, all patients were followed up for a mean period of 16 months, and only one patient had recurrence.. A unique aspect of our case series is that patients presented with features pertaining to isolated lacrimal system involvement rather than sinonasal involvement. Involvement of the nasolacrimal duct and nasal cavity without involvement of the eyes in all cases confirms the retrograde spread of rhinosporidiosis from the nasal cavity into the lacrimal sac via the nasolacrimal duct as the most common route of spread of infection. We recommend that endoscopic dacryocystorhinostomy, along with nasolacrimal duct excision used for surgical management in our case series with superior results, must become the standard of care in treatment of this condition.. 4 Laryngoscope, 128:2693-2696, 2018.

Topics: Adult; Dacryocystorhinostomy; Female; Humans; Male; Middle Aged; Nasolacrimal Duct; Natural Orifice Endoscopic Surgery; Nose; Retrospective Studies; Rhinosporidiosis; Treatment Outcome; Young Adult

Rhinosporidium seeberi is an uncultivated Ichthyosporean infecting animals, including humans. Recent studies suggested R. seeberi undergoes synchronized nuclear division without cytokinesis. We used confocal microscopy to investigate R. seeberi nuclear division cycles in formalin-fixed tissues stained with DAPI and phalloidin. We report that R. seeberi nuclei in juvenile and intermediary sporangia synchronously divided without cytokinesis. Intermediary sporangia display numerous 3-4 μm nuclei at different mitotic stages as well as a thick inner layer with strong affinity for phalloidin. Mature sporangia showed numerous 5-12 μm cell-walled endospores, each containing a 2-4 μm in diameter nucleus. Phalloidin did not bind to the inner layers of mature sporangia or endospores. The development of a "germinative zone" in the inner layer of mature sporangia containing hundreds of nuclei was also confirmed. This study establishes that during the R. seeberi life cycle synchronous nuclear divisions without cytokinesis takes place, resulting in the formation of thousands of nuclei. Cytokinesis, on the other hand, is a 1-time event and occurs in the latest stages of intermediate sporangia, after the formation of thousands of nuclei and just before mature sporangia development.

Topics: Animals; Cats; Cell Nucleus Division; Fluorescent Dyes; Horses; Humans; Indoles; Microscopy, Confocal; Nose; Phenotype; Rhinosporidiosis; Rhinosporidium

Rhinosporidiosis is a rare chronic granulomatous condition caused by a fungus (Rhinosporidium seeberi). It has been seen mainly in southern India, Sri Lanka and Pakistan. This is the first published report of a patient with multiple rhinosporidiosis. He had lesions in the nares, in multiple areas of the skin, in the external urethral meatus, glans of penis and the perineum.

Topics: Animals; Humans; Male; Middle Aged; Nose; Penis; Perineum; Rhinosporidiosis; Rhinosporidium; Scalp; Thoracic Wall

Rhinosporidiosis is endemic in the state of Chhattisgarh. 462 cases were encountered during the period of 12 years from January 1994 to December 2005. Maximum incidence was seen in men in the age group of 21-30 years. Nose and nasopharynx were the commonest site (81.1%), followed by ocular tissue (14.2%). Many rare sites of involvement were encountered. Seven cases of generalized rhinosporidiosis were seen. Rhinosporidium seeberi could be easily identified in Haematoxylin and eosin stained sections. Sporangias and spores are better delineated by periodic Acid Schiff, Mayer's mucicarmine, Verhoff's vonGieson and Grocott Gomori methamine silver stain.

Topics: Adolescent; Adult; Age Factors; Aged; Animals; Child; Child, Preschool; Endemic Diseases; Eye; Female; Humans; Incidence; India; Infant; Male; Middle Aged; Nose; Pharynx; Rhinosporidiosis; Rhinosporidium; Sex Factors; Spores, Protozoan

A young male with a single, huge subcutaneous lesion of rhinosporidiosis is reported. The diagnosis was suggested by the presence of nasal rhinosporidiosis and confirmed by fine-needle aspiration cytology (FNAC) from the skin lesion. This is the second report of giant skin lesions in rhinosporidiosis, from our department.

Topics: Adult; Diagnosis, Differential; Electrocoagulation; Humans; Leg; Male; Nose; Rhinosporidiosis

Extranasal manifestations of rhinosporidiosis are relatively uncommon. Laryngeal involvement is extremely rare, as only 3 cases have been previously reported. We describe a new case, which occurred in a patient with coexisting nasal rhinosporidiosis who presented with inspiratory stridor. Both lesions were completely excised under general anesthesia without the need for preliminary tracheostomy.

Topics: Endoscopy; Female; Humans; Laryngeal Diseases; Laryngoscopy; Larynx; Middle Aged; Nose; Nose Diseases; Rhinosporidiosis; Rhinosporidium

A case of nasal rhinosporidiosis in a 17-year-old patient from the Middle Belt area of Nigeria is described, the first such case seen in 16 years since this centre was established. The clinical features and the results of gross and microscopic examination of biopsy material are presented.

Topics: Adolescent; Female; Humans; Nigeria; Nose; Rhinosporidiosis

Topics: Humans; Nose; Rhinosporidiosis; Rhinosporidium; Staining and Labeling

Topics: Adolescent; Adult; Child; Female; Humans; India; Male; Nose; Rhinosporidiosis

Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Climate; Conjunctiva; Female; Humans; Infant; Male; Middle Aged; Nose; Paraguay; Rhinosporidiosis; Rhinosporidium; Sex Factors

Topics: Child; Hemangioma; Humans; Melanoma; Neoplasm Metastasis; Neuroblastoma; Nose; Nose Neoplasms; Rhinosporidiosis; Tuberculosis

Topics: Administration, Cutaneous; Bone and Bones; Humans; Medical Records; Mycoses; Nose; Rhinosporidiosis

Topics: Humans; Medical Records; Nose; Rhinosporidiosis

Topics: Humans; Nose; Rhinosporidiosis

Topics: Humans; Nose; Rhinosporidiosis