phenylephrine-hydrochloride and Papilloma

To demonstrate a safe and effective method for complete resection of squamous papilloma in the nasopharyngeal surface of the soft palate. This technique was used on a patient in whom the papilloma had twice recurred following uvulopalatopharyngoplasty.. Case report and review of the relevant literature.. The patient reported in this paper had recurrent squamous papilloma in the nasopharyngeal surface of the soft palate following uvulopalatopharyngoplasty. He also suffered from nasal regurgitation when drinking water. This lesion, which was difficult to access, was successfully treated via a transnasal endoscopic approach using powered instrumentation.. This case report highlights a novel approach for the complete removal of a recurrent papilloma in a relatively inaccessible location. Compared with a transoral approach such as uvulopalatopharyngoplasty, the transnasal endoscopic approach using powered instrumentation could provide a safer, faster, easier and less invasive means of treating squamous papilloma in the nasopharyngeal surface of the soft palate, especially for a lesion that recurs following a transoral approach.

Topics: Endoscopy; Humans; Male; Middle Aged; Mouth Neoplasms; Nasopharynx; Nose; Palate, Soft; Papilloma

Five cases of spectacle-frame acanthoma are reported; four were retro-auricular (three unilateral; one bilateral) and one was present on the left side of the nose. Clinical aspects of the lesions are described by the light of all the other cases that have been previously reported in the literature. Histopathological features are compared to those encountered in chondrodermatitis nodularis helicis for which a frictional origin may also be suspected. In the vast majority of cases, spontaneous resolution is obtained when responsible spectacle frames are removed whereas a few lesions persist indefinitely despite of the fact that corrective measures are applied, on the contrary to what has been reported in previous papers. Apart from removing spectacles, these few cases needed surgical excision for a complete cure. Anatomo-clinical confrontations seem to indicate that those persistent lesions are completely fissured acanthomas.

Topics: Adult; Dermatitis; Diagnosis, Differential; Ear; Ear Diseases; Eyeglasses; Humans; Male; Middle Aged; Neck; Nose; Papilloma; Skin Neoplasms

Inverted papillomas which arise from the lining membranes of the nose and paranasal sinuses are relatively unfamiliar lesions which have been reported in the literature under a variety of titles. The uncertainly surrounding their etiology, their relationship to nasal polyps and their malignant potential have resulted in an ill-defined clinical approach to their management. The designation Inverted Schneiderian Papilloma is suggested as an appropriate title that best conveys the qualities of inversion, location and distinctiveness of character. The characteristic microscopic feature is the increase in thickness of the covering epithelium with extensive invasion of this hyperplastic epithelium into the underlying stroma. In the absence of a better explanation of the origin, the tumor should be considered a true epithelial neoplasm. The clinical features in 24 previously unreported cases are presented. The most common presenting complaints are nasal obstruction and epistaxis. The common site of origin is the lateral nasal wall in the region of the middle meatus and ethmoid cells. In no instance was an isolated lesion of the maxillary, frontal or sphenoid sinus present. The most characteristic attributes of the tumor were its tendency to recur, its destructive capacity and its propensity to be associated with malignancy. The common radiographic abnormality on routine sinus films was unilateral opacification of the sinuses and nasal airway. Tomography is helpful in defining the extent of the lesion and in selecting an appropriate surgical approach. A philosophy of management has evolved based on the experiences gained from these 24 patients, combined with a review of the experience of others and a study of the regional anatomy. Surgical excision is the treatment of choice. A bold surgical approach has been used for tumors involving the lateral nasal wall and paranasal sinuses. A lateral rhinotomy incision is employed and when necessary, this exposure is increased by extending the incision of split the upper lip and reflect the cheek flap as is customarily done with the Weber-Ferfusson incision. Fifteen patients have been followed for more than two years and the results have been excellent with the exception of one patient who later developed an invasive squamous carcinoma. An associated malignancy was found in 12.5 percent of the cases.

Topics: Adult; Aged; Airway Obstruction; Carcinoma, Squamous Cell; Epistaxis; Female; Humans; Hypersensitivity; Male; Maxillary Sinus; Middle Aged; Nasal Polyps; Nose; Nose Neoplasms; Papilloma; Paranasal Sinus Neoplasms; Paranasal Sinuses; Recurrence; Sex Factors; Terminology as Topic; Tomography, X-Ray; Virus Diseases

Topics: Epistaxis; Europe; Fractures, Bone; Humans; Hypersensitivity; Hypophysectomy; Nasal Cavity; Nose; Nose Neoplasms; Papilloma; Paranasal Sinuses; Polyps; Rhinitis; Rhinitis, Atrophic

Topics: Adult; Carcinoma, Squamous Cell; Endoscopy; Humans; Laryngeal Neoplasms; Nose; Nose Neoplasms; Papilloma; Pharyngeal Neoplasms; Pharynx; Retrospective Studies; Tomography, X-Ray Computed

This report describes a combined approach to the maxillary sinus, used to deal with mucosal pathology. The technique uses a powered microdebrider with angled endoscopes and is minimally invasive. It is cost-effective and offers the potential for decreased surgical time, reduced post-operative healing time and reduced post-operative morbidity.

Topics: Chronic Disease; Endoscopes; Endoscopy; Humans; Maxillary Sinus; Nasal Polyps; Nose; Otorhinolaryngologic Surgical Procedures; Papilloma; Sinusitis; Treatment Outcome

To assess the value of endonasal sinus surgery in the management of sinonasal papillomas.. Retrospective study including 43 patients operated on for sinonasal papilloma in a long-term follow-up.. In 26 cases (60%) an endonasal approach, in eight cases (19%) an external approach, and in four cases (9%) a combined procedure was performed to remove these tumors. Five septal lesions (12%) were resected under direct vision. The original sections and charts of all patients were reviewed to assess clinical data. Follow-up information was available for 42 of our patients (98%) with a mean follow-up of 62 months.. Histologic examination revealed 34 cases of inverted papilloma (79%), five cases of exophytic papilloma (12%), and four cases of columnar cell papilloma (9%). Malignancy occurred in 4 of 43 patients (9%), and recurrences developed in 8 of 42 patients (19%). Two of these recurrences happened after endoscopic sinus surgery (two inverted papillomas), three after lateral rhinotomy (three inverted papillomas), one after a combined procedure (one inverted papilloma), and two after simple resection (two exophytic papilloma).. In keeping with our experience, the endonasal endoscopic approach, often in combination with a medial maxillectomy, is favored for the treatment of sinonasal papilloma because of a lower recurrence rate and a better cosmetic result. In some larger tumors and lesions in difficult locations, better visualization can be obtained by a combined external and endonasal approach.

Topics: Adult; Aged; Aged, 80 and over; Endoscopy; Female; Follow-Up Studies; Humans; Male; Microsurgery; Middle Aged; Nasal Septum; Neoplasm Recurrence, Local; Nose; Nose Neoplasms; Papilloma; Paranasal Sinus Neoplasms; Paranasal Sinuses; Reoperation; Tomography, X-Ray Computed; Treatment Outcome

To determine a putative role and relation between human papilloma virus (HPV) and p53 in the etiology of sinonasal carcinomas associated with papillomas.. The study group consists of all patients with sinonasal carcinomas associated with papillomas diagnosed in Denmark from 1980 to 1998. After reviewing our national pathological files, tumor tissues from 36 patients were collected, comprising 15% of the total cases of sinonasal carcinomas. In 35 cases a squamous cell carcinoma was demonstrated and in one case an adenocarcinoma was evident. Inverted papilloma was associated with carcinoma in 31 cases and exophytic papillomas in 5 cases. The material was investigated for HPV using polymerase chain reaction analyses with two sets of consensus primers (GP5+/GP6+ and MY09/MY11). The HPV-positive cases were submitted to dot-blot hybridization to establish the HPV type. Using immunohistochemistry, the p53 expression was determined. A p53 overexpression is defined as positive staining in 10% or more of the tumor cells.. Among 30 examined cases of carcinomas associated with inverted papillomas, 4 cases were HPV-positive (13%). P53 overexpression was not shown among the HPV-positive cases, whereas p53 overexpression was seen in 21 of the 24 (88%) examined HPV-negative cases. Among the 5 carcinomas associated with exophytic papillomas, HPV was demonstrated together with p53 overexpression in 3 cases (60%). In addition, one case more was with p53 overexpression.. An inverse relation between HPV and p53 overexpression in sinonasal carcinomas associated with inverted papillomas appears to have been demonstrated. HPV and p53 might also have an etiological role among the carcinomas associated with exophytic papillomas.

Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Denmark; Female; Humans; Immunoenzyme Techniques; Male; Middle Aged; Nose; Nose Neoplasms; Papilloma; Papilloma, Inverted; Papillomaviridae; Papillomavirus Infections; Paranasal Sinus Neoplasms; Paranasal Sinuses; Polymerase Chain Reaction; Retrospective Studies; Tumor Suppressor Protein p53; Tumor Virus Infections

The present study comprises 43 patients with sinonasal papillomas operated on between 1990 and 1997 at the ENT Department, University Hospital of Zurich. Histology showed 5 cases of exophytic papilloma (EP) (12%), 34 cases of inverted papilloma (IP) (79%) including 4 cases of associated carcinoma (9%), and 4 cases of columnar cell papilloma (CCP) (9%). Recurrence developed in 6 of 41 patients (2 EP, 4 IP) (15%). HPV was detected in 4 of 37 specimens (11%) both by in situ hybridization (ISH) and polymerase chain reaction (PCR). HPV-11 was found in 3 lesions (2 EP, 1 IP), whereas HPV-6b was detected only in one lesion (1 EP). Altogether 3 of 5 EP (60%), one of 29 IP (3%) and one of 6 recurrent papillomas (1 EP) (17%) tested positive for HPV. Our findings suggest a possible role for HPV in the pathogenesis of exophytic papilloma. As no correlation was found with associated malignancy and recurrence of disease, screening for HPV seems not to be useful as a prognostic parameter.

Topics: Cell Transformation, Neoplastic; Humans; In Situ Hybridization; Nose; Nose Neoplasms; Papilloma; Papillomaviridae; Papillomavirus Infections; Paranasal Sinus Neoplasms; Paranasal Sinuses; Polymerase Chain Reaction; Tumor Virus Infections

Midfacial degloving is an extended sublabial rhinotomy, which permits good bilateral access to the nasal and paranasal cavities, the base of the skull, and the clivus. The incisions leave no visible scars. The access is suitable for large benign tumours (such as nasopharyngeal fibromas or inverted papillomas), but can also be used for malignant tumours. It can be enlarged by supplementary incisions to meet the demands of tumour surgery.

Topics: Adolescent; Histiocytoma, Benign Fibrous; Humans; Maxillary Sinus Neoplasms; Methods; Nasopharyngeal Neoplasms; Nose; Nose Neoplasms; Papilloma; Paranasal Sinus Neoplasms

Inverted papilloma of the nose and paranasal sinuses is an unusual benign neoplasm that has the propensity for local tissue destruction and an association with malignant degeneration. The tumor represents an inverted growth of epithelium rather than outward proliferation. It most commonly arises from the lateral nasal wall with growth into the nose and paranasal sinuses and only rarely originates from the septum. Presenting symptoms are usually unilateral nasal obstruction and clear rhinorrhea. Surgical excision is the recommended treatment though the aggressiveness of the approach has varied. Transnasal local excision has been associated with a high recurrence rate. Lateral rhinotomy with removal of the lateral nasal wall and wide local excision has a low recurrence rate and has been the recommended treatment by most authors since 1980. However, the poor cosmetic results in some patients due to the visible external scar is especially undesirable in young females. We present a series of 23 patients treated over a ten-year period. Fifteen underwent a Denker rhinotomy and medial maxillectomy through a sublabial approach without an external incision. The recurrence rate in our group is 27% with a mean 4.7 year follow-up. This recurrence rate lies between that reported for lateral rhinotomy and local transnasal excision.

Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Nose; Nose Neoplasms; Papilloma; Paranasal Sinus Neoplasms; Postoperative Complications

Topics: Adult; Aged; Female; Humans; Lip; Male; Methods; Middle Aged; Nose; Nose Neoplasms; Papilloma; Paranasal Sinus Neoplasms

Modifying effects of the environmental contaminant catechol, and its isomers resorcinol and hydroquinone, on methyl-N-amylnitrosamine (MNAN)-induced carcinogenesis were studied in male F344 rats. Groups of 15 rats were given three i.p. injections of 25 mg/kg of body weight of MNAN within the initial 2-wk period, and commencing 1 wk thereafter they were administered 0.8% catechol, 0.8% resorcinol, or 0.8% hydroquinone in powdered basal diet or were given basal diet alone for 49 wk. Additional groups of 10 to 15 rats were similarly treated without prior carcinogen exposure. Histological examination after sacrifice at wk 52 revealed that the incidences of tongue papillomas and esophageal squamous cell carcinomas in the groups given MNAN followed by catechol (57.1% and 64.3%) or resorcinol (50% and 58.8%) were significantly higher than those in the carcinogen only controls (9.1, and 0%, respectively). Hydroquinone also enhanced the development of esophageal squamous cell carcinomas but was less active than catechol or resorcinol. The incidence of alveolar hyperplasia in the lungs of the group given MNAN followed by catechol (0%) was, in contrast, significantly reduced as compared to the control value (54.5%). Hydroquinone and resorcinol showed a similar but non-significant tendency. These results indicated that the environmental contaminant, catechol and its isomers, may play a role in the development of human upper gastrointestinal cancer, in addition to exerting modifying effects in other organs.

Topics: Animals; Carcinogens; Carcinoma; Catechols; Esophageal Neoplasms; Esophagus; Hyperplasia; Lung; Male; Nitrosamines; Nose; Nose Neoplasms; Papilloma; Rats; Rats, Inbred F344; Resorcinols; Tongue; Tongue Neoplasms

Thirty cases of inverting papilloma were reviewed retrospectively. The histology was reviewed and correlated with the clinical findings. The histology, site and clinical course allow these papillomas to be divided into three types: solitary nodular inverting papilloma, multilocalized nodular inverting papilloma, and myxoid inverting papilloma. Every group has its own prognosis. This separation makes it possible to decide the therapy, particularly the extent of the operation.

Topics: Cell Transformation, Neoplastic; Epithelium; Humans; Mitosis; Nasal Polyps; Neoplasms, Multiple Primary; Nose; Nose Neoplasms; Papilloma; Paranasal Sinus Neoplasms; Paranasal Sinuses

My experience with 250 intranasal laser surgical procedures performed with the carbon dioxide laser and the surgical microscope are described. Procedures include excision and vaporization of polyps, turbinates, tumors, telangiectasias, synechiae, nasal stenoses, intranasal cysts, papillomas, and septal spurs. Avoidance of technical problems is emphasized in this article since intranasal laser surgery is, in some respects, difficult to perform. Included are practical suggestions about patient positioning, use of protective devices, and patient selection.

Topics: Granuloma; Hemangioma; Hemorrhage; Humans; Laser Therapy; Lasers; Methods; Microscopy; Nasal Polyps; Nasopharyngeal Neoplasms; Nose; Nose Diseases; Papilloma; Postoperative Complications; Turbinates; Volatilization

Total rhinotomy is a technique previously used to gain access to the sella in hypophyseal surgery. In our experience, total rhinotomy is an excellent approach not only for benign midline naso-ethmoidal lesions but also for bilateral malignant tumours of the ethmoid complex and the nose, provided that there is no dural or orbital involvement. Total rhinotomy is contraindicated for malignant lesions extending into the nasopharynx.

Topics: Adenocarcinoma; Carcinoma, Transitional Cell; Ethmoid Bone; Humans; Male; Methods; Middle Aged; Nose; Nose Neoplasms; Papilloma; Postoperative Complications; Skull Neoplasms

In rhinology, electron microscopy has been a useful research tool for the past 15 years, but provided only a few direct clinical applications. In this review, the author's work on the human nasal mucosa and the studies of other investigators are discussed, with the emphasis on allergic reactions and disturbances of the autonomous nervous system as well as the immotile cilia syndrome.

Topics: Autonomic Nervous System; Ciliary Motility Disorders; Cystic Fibrosis; Epithelium; Humans; Microscopy, Electron; Nasal Mucosa; Nose; Nose Diseases; Nose Neoplasms; Otolaryngology; Papilloma; Rhinitis, Allergic, Perennial

Inverted papilloma is notorious for recurrence and occasional association with malignancy, leading most authors to recommend lateral rhinotomy as the initial surgical approach in all cases; however, conservative surgery has been reported effective in selected cases. To assess the role of conservative procedures, 90 cases of inverted papilloma were retrospectively reviewed. Associated malignancy was rare. Conservative surgery was successful in controlling some cases, but often required two or three operations. All patients with clear sinus films were cured by a single procedure. Abnormal mitotic activity was seen in some aggressive lesions and some associated with malignancy. The surgical exposure in inverted papilloma should be adequate to ensure complete excision. Selected patients with localized disease can be satisfactorily managed by conservative procedures if they are carefully followed. All tissue should be inspected for possible malignancy.

Topics: Adult; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Humans; Male; Middle Aged; Mitotic Index; Neoplasm Recurrence, Local; Neoplasms, Multiple Primary; Nose; Nose Neoplasms; Papilloma; Prognosis; Radiography; Retrospective Studies; Risk

Report on 22 cases of inverted papilloma. The common site of origin of the tumours is the lateral nasal wall and with a few exceptions they are benign. They become dangerous if they invade the bony structures of the face skeleton, especially the hard palate and the orbit. The therapy of choice is lateral rhinotomy with an "en bloc" resection of the lateral wall of the nose and the ethmoid of the invaded side. In that case the prognosis is good. The classifications by Schneider and Skolnik only define the size of the tumour but do not give an indication of prognosis; they are, therefore, unnecessary.

Topics: Adult; Aged; Diagnosis, Differential; Epithelium; Female; Humans; Male; Middle Aged; Mucous Membrane; Nasal Polyps; Nose; Nose Neoplasms; Papilloma; Paranasal Sinus Neoplasms; Paranasal Sinuses

Inverted nasal papillomas are rare tumors in children. Four large series include only a single patient (of a total of 269) younger than 20 years. We report the occurrence of an inverted nasal papilloma in a 10-year-old boy; this tumor exhibited clinical and histopathologic features identical to those of similar neoplasms in adults. Inverted papillomas in children should be treated by wide local excision, usually using a lateral rhinotomy approach. The rationale for such aggressive surgery is based on the high rate of recurrence (25% to 75%) and a propensity for the development of carcinomas (5% to 15%) as associated lesions.

Topics: Child; Humans; Male; Nasal Cavity; Nose; Nose Neoplasms; Papilloma

A study of 43 cases of inverted papilloma of the nose has been made. These cases, arising from a moderately well-defined geographical area, were seen between 1955 and 1980. A detailed clinical and histological review was made in each case. No correlation has been found between any of the variable histological features and the potential of a particular papilloma to recur. The overall incidence of transformation to carcinoma is low, even after multiple recurrences. The findings suggests that there may be an extrinsic factor contributing to the causation of these tumours.

Topics: Adult; Aged; Air Pollution; Female; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Nose; Nose Neoplasms; Occupational Diseases; Papilloma

A group of 31 patients with inverted papilloma were treated at the Mount Sinai Medical Center. There were no multicentric cases, and one patient had an associated malignancy. A conservative procedure consisting of intranasal or transantral sphenoethmoidectomy was selectively performed in 8 patients with limited lesions. No recurrences were observed in this group after a mean follow-up of 2 years. Lateral rhinotomy with medial maxillectomy and en bloc resection of the ethmoid labyrinth was performed in 23 other patients. One recurrence appeared in this group, members of which were followed a mean of 3.8 years. Radiographic evaluation by multidirectional polytomography and CT scanning permits identification of a small group of patients who have limited lesions and may be candidates for conservative tumor excision.

Topics: Adolescent; Adult; Aged; Female; Humans; Male; Methods; Middle Aged; Neoplasm Recurrence, Local; Nose; Nose Neoplasms; Papilloma; Paranasal Sinuses; Tomography, X-Ray Computed

Tumor development was examined sequentially in the nasal cavity of male F344 rats given 0.01% 1,4-dinitrosopiperazine (DNP) in their drinking water for various periods. Rats were sacrificed at 10-week intervals for up to Week 50. On continuous DNP administration, simple hyperplasia of the nasal cavity epithelium was observed from Week 10, papillary hyperplasia, nodular hyperplasia, and papilloma was observed from Week 20, and carcinoma was observed from Week 30. Carcinoma was observed in 100% of the animals given DNP for 50 weeks. The carcinomas were adenocarcinomas (86%), adenosquamous cell carcinomas (10%), and undifferentiated carcinomas (4%). Simple hyperplasia was distributed evenly in the nasal cavity. Seventy % of the nodular hyperplasias and 81% of the carcinomas were located in the ethmoturbinate and about 75% of the papillary hyperplasias and papillomas were located in the nasoturbinate and maxilloturbinate. These findings suggest that nodular hyperplasia is very important as a precursor of carcinoma in the nasal cavity of rats treated with DNP and that papilloma is less important in relation to carcinoma development.

Topics: Animals; Carcinogens; Carcinoma; Hyperplasia; Male; Neoplasms, Experimental; Nitrosamines; Nose; Nose Neoplasms; Papilloma; Rats; Rats, Inbred F344

Inverted papillomas are primarily lesions of the lateral nasal wall, but similar papillomas have been observed on the nasal septum. There is controversy as to whether papillomas on the septum should be considered differently from those of the lateral nasal wall and paranasal sinuses. A review of the records of the Massachusetts Eye and Ear Infirmary, Boston, disclosed 18 cases of inverted papilloma of the nasal septum that were treated before January 1968 and January 1980. The histologic diagnosis of inverted papilloma was confirmed by pathologists who examined histologic slides from these cases; these slides had been randomly mixed with slides of nasal vestibule squamous papillomas and slides of inverted papillomas of the lateral nasal wall. Squamous papillomas of the vestibule were readily distinguished microscopically from inverted papillomas of the septum and lateral wall that were histologically similar. The clinical course of these patients suggests that inverted papillomas of the nasal septum behave like inverted papillomas elsewhere and require wide surgical excision and careful follow-up.

Topics: Adult; Female; Humans; Male; Middle Aged; Nasal Septum; Nose; Nose Neoplasms; Papilloma; Paranasal Sinuses

Intranasal papilloma is an uncommon, benign tumor of the nasal cavity and, by extension, the paranasal sinuses. It occurs only once for every 25 cases of ordinary nasal polyps. A recent case is reported, followed by a summary of the cases treated at the Emory University Hospitals in the last ten years. The histologic classification is reviewed, as well as current treatment, with an emphasis on wide surgical excision through the lateral rhinotomy approach. Because about 10% of these tumors will have associated malignancy, guidelines are given to insure that this malignant transformation is not missed.

Topics: Adult; Aged; Biopsy; Female; Follow-Up Studies; Humans; Male; Methods; Middle Aged; Neoplasm Recurrence, Local; Nose; Nose Neoplasms; Papilloma; Paranasal Sinus Neoplasms; Paranasal Sinuses; Sex Factors

Topics: Carcinoma, Squamous Cell; Cystadenoma; Epithelial Cells; Epithelium; Humans; Melanocytes; Melanoma; Nasopharyngeal Neoplasms; Neuroectodermal Tumors, Primitive, Peripheral; Nose; Nose Neoplasms; Papilloma

Topics: Candidiasis, Oral; Chordoma; Darier Disease; Dermatitis; Diagnosis, Differential; Erythema; Gingival Neoplasms; Herpes Simplex; Humans; Hypersensitivity; Nose; Palatal Neoplasms; Papilloma; Precancerous Conditions; Purpura; Skin Diseases; Skin Neoplasms; Syndrome

Topics: Carcinoma in Situ; Carcinoma, Transitional Cell; Diagnosis, Differential; Ethmoid Sinus; Frontal Sinus; Humans; Male; Maxillary Sinus; Middle Aged; Nasal Polyps; Neoplasm Recurrence, Local; Nose; Nose Neoplasms; Papilloma; Paranasal Sinus Neoplasms

Topics: Humans; Lymph Nodes; Lymphatic Metastasis; Male; Middle Aged; Nose; Nose Neoplasms; Papilloma

Topics: Adult; Aged; Diagnosis, Differential; Facial Neoplasms; Female; Humans; Male; Middle Aged; Nasal Polyps; Nose; Papilloma

Topics: Adolescent; Adult; Aged; Basement Membrane; Cell Division; Cell Nucleus; Child; Cilia; Cytoplasm; Epithelium; Female; Glycogen; Humans; Inclusion Bodies; Keratins; Male; Middle Aged; Mucus; Nasal Mucosa; Nasal Septum; Neoplasm Recurrence, Local; Nose; Nose Neoplasms; Papilloma; Paranasal Sinus Neoplasms; Paranasal Sinuses

Topics: Adult; Aged; Carcinoma, Papillary; Carcinoma, Transitional Cell; Follow-Up Studies; Humans; Male; Middle Aged; Nasopharyngeal Neoplasms; Nasopharynx; Nose; Nose Neoplasms; Papilloma; Paranasal Sinus Neoplasms; Paranasal Sinuses

Topics: Humans; Male; Nose; Nose Neoplasms; Papilloma; Paranasal Sinus Neoplasms; Paranasal Sinuses; Radiography

Topics: Brain Diseases; Cerebral Ventricle Neoplasms; Cerebrospinal Fluid Rhinorrhea; Fistula; Humans; Hydrocephalus; Intracranial Pressure; Nose; Papilloma; Pneumoencephalography; Subarachnoid Space

Topics: Child; Epithelium; Humans; Male; Nose; Papilloma

Topics: Adult; Age Factors; Carcinoma; Carcinoma, Squamous Cell; Female; Humans; Male; Nose; Nose Neoplasms; Papilloma; Paranasal Sinus Neoplasms; Paranasal Sinuses; Sex Factors

Topics: Electrons; Humans; Microscopy; Microscopy, Electron; Nose; Nose Neoplasms; Papilloma; Pathology

Topics: Carcinoma, Squamous Cell; Humans; Nose; Nose Neoplasms; Papilloma; Paranasal Sinus Neoplasms; Paranasal Sinuses

Topics: Humans; Nose; Nose Neoplasms; Papilloma

Topics: Adenocarcinoma; Adenocarcinoma, Papillary; Carcinoma, Transitional Cell; Humans; Nasal Polyps; Neoplasms; Nose; Nose Neoplasms; Papilloma; Paranasal Sinus Neoplasms; Paranasal Sinuses

Topics: Humans; Nasal Polyps; Nose; Papilloma; Paranasal Sinus Neoplasms; Paranasal Sinuses

Topics: Humans; Medical Records; Neoplasms; Nose; Nose Neoplasms; Papilloma; Paranasal Sinus Neoplasms; Paranasal Sinuses

Topics: Humans; Neoplasms; Nose; Nose Neoplasms; Papilloma; Paranasal Sinus Neoplasms; Paranasal Sinuses

Topics: Humans; Medical Records; Nose; Nose Neoplasms; Papilloma

Topics: Carcinoma, Basal Cell; Humans; Nasal Cavity; Neoplasms; Nose; Papilloma; Paranasal Sinus Neoplasms; Skin Neoplasms

Topics: Humans; Nasal Cavity; Neoplasms; Nose; Papilloma; Paranasal Sinus Neoplasms