phenylephrine-hydrochloride and Nevus--Pigmented

Total excision of congenital melanocytic nevi (CMN) is not always feasible. We here present our experience of using carbon dioxide laser and Q-switched neodymium-doped yttrium-aluminum-garnet (Nd:YAG) laser to treat nodular CMN of the nasal ala. Q-switched Nd:YAG laser and/or carbon dioxide laser were used to treat eight cases of nasal ala nodular CMN. Carbon dioxide laser was utilized to ablate all visible melanocytic tissue within one session. Ablation was performed so as to reproduce the original anatomical contours as closely as possible. Recurrences were treated in the same way. Q-switched Nd:YAG laser was also used to irradiate all target lesions to achieve the desired end point within one session. The intervals between treatments were at least 8 weeks. Recurrence of melanocytic tissue, scar formation, pigmentation, depigmentation, and the degree of patient satisfaction were recorded at every visit. Two of the eight patients were treated with Q-switched Nd:YAG laser. Although, the lesion lightened in one of them, the hyperplastic tissue persisted. Eventually, these two patients, along with the remaining six patients, were successfully treated with a carbon dioxide laser. We recommend carbon dioxide laser treatment for nodular nasal CMN. This simple treatment does not involve skin flap transplantation and has good cosmetic outcomes. Although Q-switched Nd:YAG laser does lighten some nasal nodular CMNs, it does not eradicate the hyperplastic tissue, and is therefore not an effective treatment for nodular nasal CMN.

Topics: Adolescent; Child; Cicatrix; Female; Humans; Laser Therapy; Lasers, Gas; Lasers, Solid-State; Male; Nevus, Pigmented; Nose; Patient Satisfaction; Skin Neoplasms; Treatment Outcome; Young Adult

Congenital and pediatric nasal lesion resection and their reconstructive outcomes are not well studied. A surgeon must consider the site, size, depth, etiology, age, and effect on future function (including growth). As such, it is important to contrast the differences between the adult's and child's nose. The authors propose that more conservative resection and reconstructive methods may better serve congenital and pediatric nasal lesions. An Internal Review Board approved study of congenital and pediatric nasal lesions using a defect only approach from 2005 to 2017 was performed. Lesions, type of surgeries, complications, aesthetic outcome, and additional interventions were reviewed. One hundred twenty-seven patients met the study criteria with a median age at surgery of 5.4 years with follow-up of 1.4 years (1 week-11.3 years). The most common diagnosis was congenital melanocytic nevus (47, 37%). The lesions were located on more than 1 subunit in 34 (27%) patients with an average surface area of 3.7 (0.04-32) cm. The most common primary procedure was excision and primary closure with adjacent tissue undermining/rearrangement (73, 57.4%) followed by full-thickness skin graft (23, 18.1%). The aesthetic outcome was considered acceptable in a high number of patients 117 (92%), while 10 (8%) patients had unacceptable aesthetic outcomes, mostly due to scarring. The authors' data supports the concept of minimal healthy tissue excision or lesion only excision when treating pediatric and congenital nasal lesions.

Topics: Adolescent; Child; Child, Preschool; Cicatrix; Female; Humans; Male; Nevus, Pigmented; Nose; Plastic Surgery Procedures; Skin Transplantation; Young Adult

To investigate and compare the effectiveness of perichondrial cutaneous graft (PCCG) of dorsal auricle for repairing defect after excision of melanocytic nevus in different parts of the face.. Between February 2008 and October 2012, 29 cases of facial melanocytic nevus were admitted. There were 11 males and 18 females, aged 3-25 years (median, 11 years). The locations were the upper eyelid in 5 cases, the nose in 15 cases, and the buccal region in 9 cases. The size of the nevi ranged from 1.2 cm x 1.0 cm to 4.0 cm x 2.2 cm. Defects after excision of nevi were repaired by PCCG of the dorsal auricle, which size ranged from 1.5 cm x 1.5 cm to 4.2 cm x 2.5 cm. The postoperative effectiveness was scored by patients according to color match, scar formation, and flatness of the reception site. The satisfaction evaluations were compared by the score among different parts.. All the PCCG survived. All the patients were followed up 7-15 months (mean, 10 months). All the reception site had good color match and acceptable scar formation. The nasal part had good flatness, and the upper eyelid had poor flatness. Score comparison showed no significant difference in color match between 3 parts (P > 0.05). Nasal part had significantly less scar formation than buccal region and upper eyelid (P < 0.05), but no significant difference between buccal region and upper eyelid (P > 0.05). Nasal part and buccal region both had significantly better flatness than upper eyelid (P < 0.05), but no significant difference between nasal part and buccal region (P > 0.05). The overall evaluation score of nasal part and buccal region was significantly higher than that of the upper eyelid group (P < 0.05), and the score of the nasal part was significantly higher than that of the buccal region (P < 0.05).. PCCG of dorsal auricle has a good color match in repair of facial defect, especially in repair of nasal defect with good flatness and no obvious scar formation.

Topics: Adolescent; Adult; Child; Child, Preschool; Ear, External; Face; Facial Neoplasms; Female; Humans; Male; Nevus, Pigmented; Nose; Plastic Surgery Procedures; Skin; Skin Neoplasms; Skin Transplantation; Soft Tissue Injuries; Surgical Flaps; Treatment Outcome; Wound Healing; Young Adult

Crescentic subcutaneous pedicle flaps prepared on the area lateral to the alar base were designed to cover the skin defects in and around the philtrum. In 1 patient a combination of the lateral lip advancement flap and the crescentic subcutaneous pedicle flap was applied to the skin defect on the lateral lip and philtrum. In another patient, a combination of two crescentic subcutaneous pedicle flaps was applied to the skin defect within the philtrum. Both methods have been successful.

Topics: Adult; Humans; Lip; Lip Neoplasms; Male; Nevus, Pigmented; Nose; Surgical Flaps

After 15 years of experience and 50 cases, we think that the axial frontonasal flap is of great value for the repair of large skin defects of the nose. This flap mobilizes all the skin cover of the nose located above the defect and the adjacent frontal skin and rotates it on a vascular pedicle existing at the level of the inner canthi. The excess of skin of the glabella is then transferred to the nose, and this large flap allows coverage of the defect without tension or distortion. The long-term results are very good, with a hardly visible repair in 26 of 50 patients, the long scar being very well hidden at the periphery of the nose.

Topics: Adult; Aged; Carcinoma, Basal Cell; Face; Female; Humans; Male; Melanoma; Middle Aged; Nevus, Pigmented; Nose; Nose Neoplasms; Skin; Surgical Flaps

Topics: Child; Child, Preschool; Congenital Abnormalities; Dermoid Cyst; Disorders of Sex Development; Ear, External; Eyebrows; Facial Neoplasms; Female; Fistula; Hemangioma; Hemangioma, Cavernous; Humans; Infant; Male; Neck; Nevus, Pigmented; Nose; Nose Neoplasms; Penis; Skin Neoplasms

Electron microscopic examination of malignant melanoma tumour tissue taken from a patient who has survived with the tumour without metastases for 13 years has shown spherical melanosomes with no internal fibrillar structure. This finding and other cell features described, suggest that this melanoma developed from Dubreuilh's melanosis rather than melanocytic change in a junctional naevus.

Topics: Adolescent; Cell Nucleus; Female; Humans; Melanocytes; Melanoma; Nasal Cavity; Nevus, Pigmented; Nose; Nose Neoplasms; Organoids; Precancerous Conditions; Vacuoles

Topics: Adult; Asian People; Cicatrix; Cleft Lip; Dermoid Cyst; Female; Glioma; Head; Humans; Hypertrophy; Japan; Male; Middle Aged; Nevus, Pigmented; Nose; Nose Deformities, Acquired; Nose Neoplasms; Pigmentation Disorders; Postoperative Care; Postoperative Complications; Rhinoplasty; Skin Neoplasms; Skin Transplantation; Transplantation, Autologous

The plastic surgeon is not a miracle worker, as so many of his patients believe. Nevertheless, he can do much to minimize the functional and cosmetic effect of many congenital deformities. If a moral can be drawn from this article it must be that the plastic surgeon should be given an early opportunity to see and assess the patients described here, if only to ease the anxiety in the minds of their parents by appropriate reassurance and discussion.

Topics: Arteriovenous Malformations; Breast; Congenital Abnormalities; Dermoid Cyst; Ear; Female; Fingers; Humans; Hypospadias; Leg; Lymphangioma; Lymphedema; Male; Nevus; Nevus, Pigmented; Nose; Skin Neoplasms; Surgery, Plastic; Vagina; Wrist

Topics: Adolescent; Adult; Aged; Biopsy; Connective Tissue; Female; Histocytochemistry; Humans; Male; Middle Aged; Nevus; Nevus, Pigmented; Nose; Nose Neoplasms; Periodic Acid; Skin; Skin Neoplasms; Staining and Labeling

Topics: Electroencephalography; Epilepsy, Temporal Lobe; Female; Head and Neck Neoplasms; Humans; Infant; Nevus, Pigmented; Nose; Scalp; Sebaceous Glands; Skin Neoplasms

Topics: Breast Diseases; Congenital Abnormalities; Humans; Nevus; Nevus, Pigmented; Nose; Nose Deformities, Acquired; Obesity; Plastics; Prognathism; Skin Neoplasms; Surgery, Plastic

Topics: Adolescent; Adult; Aged; Humans; Middle Aged; Nevus, Pigmented; Nose; Skin Neoplasms

Topics: Humans; Nevus; Nevus, Pigmented; Nevus, Sebaceous of Jadassohn; Nose; Nose Neoplasms; Pathology; Sebaceous Glands; Skin Neoplasms; Surgical Procedures, Operative

Topics: Breast; Cleft Lip; Humans; Nevus; Nevus, Pigmented; Nose; Nose Neoplasms; Skin Neoplasms; Surgery, Plastic

Nevi are the most common tumors of childhood. Pigmented nevi are classified into blue nevi, intraepidermal nevi, junction nevi, intradermal nevi (or common mole) and combination types. Cutaneous malignant disease in children is rare. Malignant melanoma is rare before puberty. Wholesale removal of benign pigmented nevi in children should be condemned. However, junction nevi located on the palms, soles, genitalia or waistline-that is, in areas subject to frequent trauma-should be excised. Hemangiomas in infants are the most common tumors for which advice is sought. Not all hemangiomas regress spontaneously, and on occasion the persistence or progression of such a lesion may bring about life-long unsightly deformities. Therapy for this type of tumor is simple when given early in life. Hemangiomas involving the ears, nose, lips or eyelids should be treated at once, preferably within a month of the time they appear.

Topics: Administration, Cutaneous; Child; Disease Progression; Eyelids; Foot; Hemangioma; Humans; Infant; Lip; Melanoma; Nevus; Nevus, Blue; Nevus, Epithelioid and Spindle Cell; Nevus, Intradermal; Nevus, Pigmented; Nose; Skin Neoplasms