phenylephrine-hydrochloride and Myopia

Stickler syndrome is an autosomal dominant disease characterized by various disorders of the eyes and the connective tissues throughout the body. It can arise from a mutation in the collagen associated gene. We present a case of Stickler syndrome with rhegmatogenous retinal detachment.. A 10-years-old boy was referred to us with rhegmatogenous retinal detachment of the right eye. His family history included eye disease and a cleft palate. He had high myopia, vitreous liquefaction and lattice degeneration in the both eye. He also had a cleft palate and a broad nasal bridge. His condition was diagnosed as Stickler syndrome. We performed vitrectomy, scleral buckling and encircling, and silicone oil injection in the right eye. We also did a reattachment of the retina in the right eye.. Pediatric retinal detachment may indicate the presence of Stickler syndrome and a complete examination of the eye as well as a full family history must be obtained in such cases.

Topics: Child; Cleft Palate; Eye Diseases; Fibrillar Collagens; Genes, Dominant; Humans; Injections, Intraocular; Male; Mutation; Myopia; Nose; Retinal Detachment; Scleral Buckling; Silicone Oils; Syndrome; Vitrectomy; Vitreous Body

Transnasal endoscopic orbital decompression is emerging as a new minimally invasive technique that avoids the need for cutaneous or gingival incision. This surgical approach appears to be a safe and effective procedure, even for the treatment of ocular disease, and it can be performed under general or local anaesthesia. The authors present a case of severe monolateral non-Graves' axial exophthalmos, accompanied by severe anisometropic myopia, which was treated successfully with functional endoscopic sinus surgery. The minimally invasive surgical procedure resulted in a marked reduction of exophthalmos without any severe complications and with minimal discomfort for the patient, who was discharged from hospital on the fourth postoperative day.

Topics: Anisometropia; Endoscopy; Exophthalmos; Female; Humans; Magnetic Resonance Imaging; Middle Aged; Myopia; Nose

Two new familial cases of Marshall syndrome are reported. The main features of this rare syndrome are outlined. Its possible relationship with Stickler syndrome is discussed.

Topics: Abnormalities, Multiple; Adult; Cataract; Female; Hearing Loss; Hearing Loss, Bilateral; Humans; Infant, Newborn; Male; Myopia; Nose; Pedigree; Syndrome

Topics: Adult; Child; Deafness; Female; Genetic Variation; Humans; Male; Myopia; Nose; Syndrome; Terminology as Topic; Zygoma

Retinal detachment is unusual in children and is often associated with other serious ocular abnormalities. In more than 25 children varying in age from 3 to 16 years in whom the common ocular complication was congenital myopia, associated features included facial abnormalities and other changes often associated with familial and inherited conditions. A very high incidence of giant retinal breaks was found and these were associated with considerable difficulty in treatment.

Topics: Adolescent; Adult; Child; Child, Preschool; Female; Humans; Male; Myopia; Nose; Retinal Detachment

Topics: Adolescent; Adult; Child; Chromosome Aberrations; Chromosome Disorders; Craniofacial Dysostosis; Ectodermal Dysplasia; Face; Female; Hearing Disorders; Humans; Male; Myopia; Nose; Pedigree; Radiography; Strabismus; Syndrome

Topics: Child; Congenital Abnormalities; Deafness; Eyebrows; Eyelids; Genetics, Medical; Hair; Hair Diseases; Humans; Iris; Myopia; Nose; Nose Deformities, Acquired; Pigmentation Disorders; Waardenburg Syndrome