phenylephrine-hydrochloride and Macroglossia

Positive airway pressure can be effective for OSA treatment but is not effectively used by many patients. Surgical reconstruction of the airway is appropriate for patients who are not otherwise effectively treated or as first-line treatment for patients with focal airway lesions. For surgical planning, examination schemes of the awake patient, as well as sleep endoscopy may be used. Nasal surgery may facilitate treatment using positive airway pressure or oral appliances or to improve quality of life. Pharyngoplasty and tongue base techniques for therapeutic upper airway reconstruction may be performed staged or simultaneously. Current and future approaches are described.

Topics: Endoscopy; Glossectomy; Humans; Macroglossia; Nasal Obstruction; Nose; Palate, Soft; Perioperative Care; Pharynx; Rhinoplasty; Sleep Apnea, Obstructive; Tonsillectomy

Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Epilepsy, Tonic-Clonic; Female; Fetus; Humans; Infant, Newborn; Macroglossia; Nose; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Psychomotor Disorders; Skull; Toes

The Simpson-Golabi-Behmel syndrome (SGBS) is an overgrowth condition characterised by macrosomia, mental deficiency, large head, prominent skull sutures, midface deficiency, hypertelorism, broad nose, wide mouth, macroglossia, malocclusion, highly arched palate, and musculoskeletal and limb abnormalities. The aim of this case report is to present clinical and oral findings of an 8-year-old boy who had been diagnosed with SGBS.. This patient had supernumerary nipples on the right side, cubitus valgus webbed fingers, scoliosis, umbilical hernia, a coarse face, macrocephaly, hypertelorism, a short broad nose, a wide mouth, a straight facial profile and hearing loss. The patient also had macroglossia, diastemas, over-retained primary tooth, absent mandibular permanent central incisors, and highly arched palate. Lateral cephalometric analysis revealed a large anterior cranial base, a large maxilla and mandible, a large inferior face height, and skeletal Class III jaw relationship.. After extraction of the over-retained primary central tooth, a partial prosthesis was fabricated in order to maintain function. The patient has been recalled regularly at 6-month intervals for 2 years. Over the following years the prosthesis was replaced due to facial growth.. Long term follow-up is essential for the patient with SGBS. Preventive dental care, including oral hygiene instructions, diet counselling and the use of fluoride has been implemented.

Topics: Anodontia; Arrhythmias, Cardiac; Cephalometry; Child; Denture, Partial, Removable; Diastema; Follow-Up Studies; Genetic Diseases, X-Linked; Gigantism; Heart Defects, Congenital; Humans; Hypertelorism; Incisor; Intellectual Disability; Macroglossia; Macrostomia; Male; Malocclusion, Angle Class III; Nose; Palate; Tooth, Deciduous

Besides nose obstruction other etiological factors can be advanced to explain the development of oral respiration: malformation of the face (Binder's syndrome, Bimler's microrhinodysplasia, Apert's and Crouzon's syndrome); alterations or deviations of the tongue (Robin's syndrome, macroglossia, ankyloglossia); lip closure problems.

Topics: Child; Child, Preschool; Facial Bones; Humans; Infant; Macroglossia; Malocclusion; Mouth Breathing; Nose; Syndrome; Tongue

A case of Laband syndrome in an 8-yr-old girl is presented. The case is sporadic. The patient manifests enlargement of the soft tissue of the hard palate and the gingiva, which partly or completely covers the crowns of the teeth and macroglossia. The cartilagenous part of the nose and the ears is large and soft. She has synophrys and thick, straight hair. The nails of the fingers and toes are dysplastic. The girl exhibits no other abnormality, except an IQ of 61.

Topics: Abnormalities, Multiple; Child; Female; Fibromatosis, Gingival; Humans; Intellectual Disability; Macroglossia; Nails, Malformed; Nose; Syndrome

The aim of plastic surgery in children with Down-syndrome is the improvement of speech as well as improvement of cosmetic appearance. Altering the typical mongoloid physiognomy facilitates the integration of these children into the community. In our Department during the past 6 months plastic surgery was performed in 27 children for the correction of macroglossia, saddle nose deformity, epicanthic folds, receding chin, fatty neck and deformity of the ears. Macroglossia was present in every case, the extent of further surgery varies according to the clinical deformity. It is essential to discuss the implications of surgery in these children with the parents in order to avoid later disappointment.

Topics: Child; Down Syndrome; Ear; Humans; Macroglossia; Neck; Nose; Speech Disorders; Surgery, Plastic