phenylephrine-hydrochloride and Histiocytoma--Benign-Fibrous

Alopecia present from birth includes a broad differential diagnosis and often represents a diagnostic and therapeutic challenge for the involved physician.. An initial correct diagnosis and classification is essential because structural hair defects may be the expression of a genetic disorder affecting hair growth, part of a congenital syndrome with accompanying hair malformations, or a marker for an underlying metabolic disorder and may impact the mental and physical development of a child. Pathological hair loss rarely occurs in the first year of life; however, it may be a leading symptom of many congenital diseases.. In recent years, the clinical and microscopic features of hereditary hair shaft disorders have been characterized and classified. Furthermore, significant progress has been made in our knowledge of genes that control the normal development and differentiation of hair follicles, and thus the research is to define and classify the hair disorders within a genetic basis.. In this article we discuss several types of genotrichosis and provide a practical classification based on their clinical features.

Topics: Alopecia; Aneurysm; Carcinoma, Basal Cell; Child; Cleft Lip; Cleft Palate; Deafness; Ectodermal Dysplasia; Eczema; Facies; Fingers; Growth Disorders; Hair Diseases; Hallermann's Syndrome; Histiocytoma, Benign Fibrous; Humans; Hypotrichosis; Ichthyosis; Intellectual Disability; Keratitis; Langer-Giedion Syndrome; Microcephaly; Nose; Skin Diseases, Genetic; Skin Neoplasms

Topics: Child; Female; Histiocytoma, Benign Fibrous; Humans; Neck; Nose; Otolaryngology; Pharynx

Topics: Animals; Dog Diseases; Dogs; Female; Histiocytoma, Benign Fibrous; Nose

Because of minimal donor region morbidity, pliability, the presence of long and large caliber vessels, and lack of visible scar, the free anterolateral thigh flap provides an ideal option for restoration of full-thickness nasal defects.. Full-thickness nasal defect reconstruction requires internal nasal lining and external cover. In large defects, internal nasal lining replacement with traditional sources may not be expedient. We describe reconstruction of full-thickness nasal defects with free anterolateral thigh flap.. From August 2005 to July 2007, six patients with full-thickness nasal defects underwent nasal reconstruction using free anterolateral thigh flap. All defects resulted from tumor resections. Four patients had a basal cell carcinoma, one an epidermoid carcinoma, and the other patient had recurrent malignant fibrous histiocytoma.. All flaps survived completely. The average hospitalization time was 3 days. No complication was observed.

Topics: Aged; Aged, 80 and over; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Female; Histiocytoma, Benign Fibrous; Humans; Length of Stay; Male; Middle Aged; Neoplasm Recurrence, Local; Nose; Nose Neoplasms; Plastic Surgery Procedures; Surgical Flaps; Thigh

Clear-cell changes are rare in histological specimens of the dermis and raise complex diagnostic considerations regarding lineage differentiation (e.g., epithelial, mesenchymal, or melanocytic). We present a clear-cell atypical fibroxanthoma (CCAFX) and describe the morphological and immunohistochemical aspects of this rare skin lesion. Furthermore, we give an overview of the differential diagnoses of clear-cell lesions of the skin for a practical approach.

Topics: Aged, 80 and over; Biomarkers, Tumor; Diagnosis, Differential; Female; Histiocytoma, Benign Fibrous; Humans; Immunohistochemistry; Nose; Skin Neoplasms

Midfacial degloving is an extended sublabial rhinotomy, which permits good bilateral access to the nasal and paranasal cavities, the base of the skull, and the clivus. The incisions leave no visible scars. The access is suitable for large benign tumours (such as nasopharyngeal fibromas or inverted papillomas), but can also be used for malignant tumours. It can be enlarged by supplementary incisions to meet the demands of tumour surgery.

Topics: Adolescent; Histiocytoma, Benign Fibrous; Humans; Maxillary Sinus Neoplasms; Methods; Nasopharyngeal Neoplasms; Nose; Nose Neoplasms; Papilloma; Paranasal Sinus Neoplasms

Various surgical approaches to the region are discussed, and the procedure according to Hernandez Altemir (1986) described in detail. Six cases are presented to illustrate how this versatile osteoplastic technique may be adapted for individual patients.

Topics: Adenocarcinoma; Adenoma, Pleomorphic; Adolescent; Adult; Carcinoma, Adenoid Cystic; Carcinoma, Squamous Cell; Ethmoid Bone; Face; Female; Head and Neck Neoplasms; Histiocytoma, Benign Fibrous; Humans; Male; Maxilla; Middle Aged; Neoplasms, Multiple Primary; Neurilemmoma; Nose; Nose Neoplasms; Osteoma; Osteotomy; Palatal Neoplasms; Pharynx; Skull Neoplasms

A potential for recurrence of juvenile angiofibroma exists after all treatment modalities, both surgical and medical but the methods of defining recurrence and failure to cure varies considerably from series to series. To evaluate factors which might influence successful treatment, a series of 33 patients have been reviewed retrospectively. All patients were treated by simple or extended lateral rhinotomy as a primary or secondary procedure. The final long-term disease control rate was 97% but during the treatment period the overall symptomatic recurrence rate was 50%. However, amongst those treated primarily the recurrence rate was 34%. Of the factors examined, the strongest predictor of recurrence was preoperative embolisation. This group exhibited both early and multiple recurrence when compared with the non-embolised group and the possible reasons for this are examined.

Topics: Adolescent; Embolization, Therapeutic; Histiocytoma, Benign Fibrous; Humans; Male; Nasopharyngeal Neoplasms; Neoplasm Recurrence, Local; Nose; Retrospective Studies; Risk Factors; Time Factors

Percutaneous embolization to control the nasal blood circulation was used in 19 patients with vascular nasal disorders. Embolization was the initial treatment for intractable posterior epistaxis in 11 patients, 9 (82%) of whom were controlled without further treatment. Used as an adjunct to surgery on vascular nasal tumors, embolization reduced intraoperative blood loss in four patients to an average of 800 cc. In four patients with Osler-Weber-Rendu disease, treatment with embolization did not significantly alter the course of their disease. Overall, however, this relatively new technique enhances successful management of difficult epistaxis cases.

Topics: Embolization, Therapeutic; Epistaxis; Histiocytoma, Benign Fibrous; Humans; Nose; Nose Neoplasms; Punctures; Telangiectasia, Hereditary Hemorrhagic

Nosebleed in children can result from dryness and picking of the resultant crust over the anterior part of the nasal septum, trauma to the nose, juvenile angiofibroma, or disorders of hemostatic mechanisms. In most cases it is not difficult to treat; often the primary care physician can assist a patient by giving instructions over the telephone to a parent. In the office or hospital, the usual measures are firm pressure, placement of a piece of cotton dipped in a cocaine-epinephrine solution, taking of a brief history, application of petrolatum, and taping of the nose. If bleeding persists, anterior nasal packing and, rarely, posterior packing should be performed. Maxillary artery ligation is done in cases of severe epistaxis. Special care must be taken with children who have a bleeding disorder or who are recovering from adenoidectomy.

Topics: Adenoidectomy; Blood Coagulation Disorders; Child; Epistaxis; Hemostatic Techniques; Histiocytoma, Benign Fibrous; Humans; Nasal Cavity; Nose; Nose Neoplasms; Postoperative Complications; Referral and Consultation

Topics: Histiocytoma, Benign Fibrous; Humans; Masticatory Muscles; Nasopharyngeal Neoplasms; Nasopharynx; Neurilemmoma; Nose; Paranasal Sinuses; Parotid Neoplasms; Pterygoid Muscles; Sinusitis; Tomography, X-Ray Computed

Topics: Adult; Histiocytoma, Benign Fibrous; Humans; Male; Nasal Polyps; Nose; Nose Neoplasms

Topics: Child; Dermoid Cyst; Encephalocele; Foreign Bodies; Glioma; Histiocytoma, Benign Fibrous; Humans; Nasal Polyps; Nasopharyngeal Neoplasms; Nose; Nose Neoplasms

The antrochoanal polyp, a benign solitary polypoid lesion, usually arises in a maxillary sinus, opacifying and enlarging the sinus cavity without bone destruction. It passes through the ostium of the sinus into the choana, and from there into the posterior nasopharynx. The soft tissue mass does not erode or destroy contiguous soft tissue or bony structures. In this sequence of events, its radiologic findings are characteristic. Five case reports are presented, and the differential diagnosis is discussed.

Topics: Child; Diagnosis, Differential; Female; Histiocytoma, Benign Fibrous; Humans; Male; Maxillary Sinus; Nasal Polyps; Nasopharyngeal Neoplasms; Nose; Radiography; Sinusitis

The clinical, microscopical, and gross pathological features of 14 cases of intranasal and paranasal sinus polyposis with unusual stromal cell atypia are described. In gross appearance, the lesions were polypoid, translucent masses, similar to the usual nasal polyp. Although clinically the lesions were indicative of allergic and inflammatory nasal polyposis, microscopical examination showed numerous large, often pleomorphic histiocytes or facultative fibroblasts that were suggestive or sarcomatous, malignant degeneration. Diagnoses by the original contributing pathologists included embryonal rhabdomyosarcoma, stromal neoplasia, and juvenile masopharyngeal angiofibroma. Follow-up data showed no evidence of neoplasia, despite the remarkable cytological changes found in the stroma. The stromal atypia most likely represents a reactive phenomenon secondary to inflammation.

Topics: Adolescent; Adult; Child; Child, Preschool; Diagnosis, Differential; Female; Histiocytoma, Benign Fibrous; Humans; Male; Nasal Cavity; Nasal Polyps; Nose; Paranasal Sinus Neoplasms; Paranasal Sinuses; Rhabdomyosarcoma

Topics: Cerebrospinal Fluid Rhinorrhea; Cryosurgery; Epistaxis; Fractures, Bone; Histiocytoma, Benign Fibrous; Humans; Mucous Membrane; Nasal Polyps; Nasopharyngeal Neoplasms; Nose; Nose Deformities, Acquired; Nose Diseases; Nose Neoplasms; Rhinitis; Rhinoplasty; Rosacea; Skin Neoplasms

Topics: Adolescent; Adult; Aged; Angiomatosis; Child; Ethmoid Sinus; Female; Glomus Tumor; Hemangioma; Hemangioma, Cavernous; Hemangiopericytoma; Histiocytoma, Benign Fibrous; Humans; Male; Maxillary Sinus; Middle Aged; Nasal Septum; Nasopharyngeal Neoplasms; Nasopharynx; Neoplasms, Vascular Tissue; Nose; Nose Neoplasms; Paranasal Sinus Neoplasms; Paranasal Sinuses; Turbinates

Topics: Bone Transplantation; Child; Cleft Lip; Cleft Palate; Histiocytoma, Benign Fibrous; Humans; Male; Nasopharyngeal Neoplasms; Nose; Nose Deformities, Acquired; Rhinoplasty; Skin Transplantation; Transplantation, Autologous

Topics: Anemia; Arteriosclerosis; Deafness; Diagnosis, Differential; Ear; Hemangioma; Hematologic Diseases; Hematoma; Hemophilia A; Histiocytoma, Benign Fibrous; Humans; Infectious Mononucleosis; Leukemia; Nose; Pathology; Pharynx; Polycythemia; Telangiectasis

Topics: Adenoma; Congenital Abnormalities; Hemangioma; Histiocytoma, Benign Fibrous; Humans; Mouth Neoplasms; Nasal Cavity; Nasopharyngeal Neoplasms; Nose; Plasmacytoma; Surgical Procedures, Operative