phenylephrine-hydrochloride and Hemangiosarcoma

Angiosarcoma is an aggressive neoplasm that predominantly affects elderly patients. Most cases appear on the scalp and face de novo; however, trauma, longstanding lymphedema, and irradiation are predisposing factors. Management includes a multidisciplinary team and may involve a combination of surgery, radiation, and chemotherapy tailored to the patient's age and associated comorbidities.

Topics: Aged, 80 and over; Diagnosis, Differential; Hemangiosarcoma; Humans; Male; Nose; Radiotherapy, Adjuvant; Skin Neoplasms

A case of angiosarcoma arising from the nose of a 69-year-old man is presented in this report. The patient was treated with a combination of recombinant interleukin-2 (rIL-2, Celeuk), electron beam irradiation, and surgery. He died 27 months after diagnosis, but there was no apparent remote metastasis.

Topics: Aged; Biopsy, Needle; Combined Modality Therapy; Fatal Outcome; Hemangiosarcoma; Humans; Immunohistochemistry; Interleukin-2; Japan; Male; Nose; Radiotherapy, Adjuvant; Skin Neoplasms; Surgical Procedures, Operative

This case report describes a man in his 60s who was referred to the department of dermatology for further evaluation of a lesion on the nose.

Topics: Hemangiosarcoma; Humans; Nose; Nose Neoplasms; Rhinophyma

Cosmetic consultations are routinely part of a dermatologist’s day. Often, patients present after consultation from another dermatologist or other physician with an established diagnosis and would like a particular treatment to resolve their condition. However, it is imperative to take a full history and physical exam prior to rendering treatment in the event of a missed or new diagnosis.

Topics: Biopsy; Cosmetic Techniques; Hemangiosarcoma; Humans; Lasers; Male; Middle Aged; Nasal Surgical Procedures; Nose; Radiotherapy, Adjuvant; Skin Neoplasms

Angiosarcoma also called malignant hemangioendothelioma, caused by vascular endothelial cells or in the direction of vascular endothelial cell differertiation of mesenchymal malignant tumor, is a rare tumor found in clinical, can be in any place of the body, such as head and neck, skin and tissue, breast, bone, liver and other organs and so on, also in the nose, and sinuses rich blood vessels. But this tumor has a low incidence in the nose. Because the nose and sinuses location is hidden, the patient often with nasal bleeding, stuffy nose, headache and so on. With the increase of tumor involvement, the patient can appears the symptoms of corresponding adjacent tissue. Therefore this tumor is difficult to be early detected timely. Early complete surgical excision and supplemented by radiotherapy are preferred methods as the treatments of the nasal and sinuses angiosarcoma without distant metastase.

Topics: Hemangiosarcoma; Humans; Nasal Cavity; Nose; Nose Neoplasms; Paranasal Sinus Neoplasms; Paranasal Sinuses

Topics: Aged, 80 and over; Biopsy; Diagnosis, Differential; Follow-Up Studies; Hemangiosarcoma; Humans; Male; Nose; Nose Neoplasms; Photons; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Skin; Skin Neoplasms

Angiosarcomas are rare, aggressive tumors of vascular origin. They occur most often in areas of long term sun exposed skin in the elderly, in long standing lymphoedema or after radiation therapy. The prognosis is poor, radical surgery required, in addition radiation or chemo-therapy are considered to be therapeutical options. We report on a male patient, 70 years old with a slightly bleeding blueish tumor encompassing the complete nose. This patient treated with several antibiotics while continuous growth led to the described course. After 4 months a biopsy was taken revealing an angiosarcoma of the nose. Subsequently the patient was referred to our department and due to staging results a surgical therapy (ablatio nasi) followed. The final histological diagnosis was a low grade angiosarcoma of the cutaneous and subcutaneous tissue of the nose without infiltration of bone or cartilage, confirmed by immunohistological staining. Angiosarcomas of the head and neck region are extremely rare. Especially only few cases of nasal angiosarcoma infiltrating the complete nose are described in literature. Prognosis, therapy and differential diagnosis have to be discussed.

Topics: Aged; Biopsy; Hemangiosarcoma; Humans; Male; Nose; Nose Neoplasms; Prognosis; Skin; Skin Neoplasms; Surgical Flaps

We report the case of a 69-year-old man who had a persistent lesion develop on his nose during a 1-year period of time that was diagnosed as rhinophyma. Despite laser treatment the lesion continued to grow. Histopathology and immunohistochemical studies were consistent with cutaneous angiosarcoma. Rhinophyma-like features should be considered as an unusual clinical manifestation of cutaneous angiosarcoma.

Topics: Aged; Biopsy, Needle; Combined Modality Therapy; Diagnosis, Differential; Follow-Up Studies; Hemangiosarcoma; Humans; Immunohistochemistry; Male; Nose; Radiotherapy, Adjuvant; Rhinophyma; Risk Assessment; Skin Neoplasms; Surgical Procedures, Operative; Treatment Outcome

Topics: Aged; Biopsy, Needle; Female; Follow-Up Studies; Hemangiosarcoma; Humans; Immunohistochemistry; Mohs Surgery; Nose; Skin Neoplasms

Topics: Aged; Hemangiosarcoma; Humans; Male; Neoplasm Recurrence, Local; Nose; Nose Neoplasms; Skin

A case is presented in which angiosarcoma of the nose was found in a patient with rhinophyma. To the best of our knowledge, this constellation has not previously been reported.

Topics: Aged; Hemangiosarcoma; Humans; Male; Nose; Nose Neoplasms; Rhinophyma; Rosacea

Topics: Bone Neoplasms; Chondrosarcoma; Ear, External; Hemangiosarcoma; Humans; Medical Records; Neoplasms; Nose; Nose Neoplasms; Tuberculosis