phenylephrine-hydrochloride and Hearing-Loss

Topics: Abdominal Pain; Adult; Ascitic Fluid; Early Detection of Cancer; Hearing Loss; Humans; Male; Myofibroblasts; Nose; Pleural Effusion; Sarcoma; Treatment Outcome

The endoscopic endonasal approach (EEA) has proven to be a valuable tool to access the petrous apex (PA).

Topics: Cranial Fossa, Middle; Female; Granuloma; Hearing Loss; Humans; Middle Aged; Nose; Petrous Bone

Homeless individuals frequently experience poor access to healthcare, delayed clinical presentation, and higher disease burden. Providing subspecialty otolaryngology care to this population can be challenging. We previously reported on the prevalence of hearing impairment in Toronto's homeless community. As a secondary objective of this study, we sought to define otolaryngology specific need for this population.. One hundred adult homeless individuals were recruited across ten homeless shelters in Toronto, Canada using a stratified random sampling technique. An audiometric evaluation and head and neck physical examination were performed by an audiologist and otolaryngology resident, respectively. Basic demographic and clinical information was captured through verbal administration of a survey. Descriptive statistics were used to estimate frequency of otolaryngology specific diseases for this population.. Of the 132 individuals who were initially approached to participant, 100 (76%) agreed. There were 64 males, with median age of 46 years (IQR 37-58 years). The median life duration of homelessness was 24 months (IQR 6-72 months). Participants had a wide range of medical comorbidities, with the most common being current tobacco smoking (67%), depression (36%), alcohol abuse (32%), and other substance abuse (32%). There were 22 patients with otolaryngology needs as demonstrated by one or more abnormal findings on head and neck examination. The most common finding was nasal fracture with significant nasal obstruction (6%). Eleven patients required referral to a staff otolaryngologist based on concerning or suspicious findings, including two head and neck masses, 6 were later seen in follow-up.. There were substantial otolaryngology needs amongst a homeless population within a universal healthcare system. Future research should focus on further elucidating head and neck related issues in this population and expanding the role of the otolaryngologist in providing care to homeless individuals.

Topics: Adult; Audiometry; Comorbidity; Female; Head and Neck Neoplasms; Health Surveys; Hearing Loss; Humans; Ill-Housed Persons; Male; Middle Aged; Nose; Ontario; Otolaryngology; Otorhinolaryngologic Diseases; Prospective Studies

To explore the feasibility and related aspects on endoscopic endonasal management of petrous apex cholesterol granuloma.. Retrospective data analysis was performed on 3 cases in which the endoscopic endonasal approach was used to manage this lesion between 2011 and 2014. Case information including radiological data, surgical technique, symptoms, and complications was reviewed.. The main clinical manifestations in these 3 patients were tinnitus, hearing loss at the hearing threshold of 40-50 dBHL. After operation, all 3 patients showed disappearance of their tinnitus and improvement of the hearing threshold of 10-30 dBHL (follow-up 6-45 months). Permanent drainage route was performed in 1 case which communicated with sphenoid sinus. While the other 2 cases which drained to pharyngeal recess resulted in drainage route blocking within the 3-6 months after surgery, but without obvious symptoms.. This procedure for the drainage of petrous apex cholesterol granuloma showed to be effective, safe and minimally invasive. Although there is no recurrence in short-term, however, long-term surveillance and large case series are necessary, especially to the maitainence of permanent drainage.

Topics: Cholesterol; Drainage; Endoscopy; Granuloma, Foreign-Body; Hearing Loss; Humans; Nose; Petrous Bone; Recurrence; Retrospective Studies; Sphenoid Sinus; Tinnitus

Scuba diving is known to affect the rhino-pharyngo-tubaric district (RPT unit). The aim of the study was to document function modifications of the RPT unit in 6 Italian divers (3 men and 3 women) who lived for 14 days consecutively at a depth of 8-10 m, breathing air (21% oxygen) at a pressure ranging between 1.8 and 2 ATA. RPT and inner ear assessment were carried out before the dive (TIME 0) and 24 h (TIME 1) after resurfacing, in order to investigate diving-related RPT and inner ear alterations. Physical examination after resurfacing revealed: fungal external otitis, otoscopic findings consistent with middle ear barotraumas and rhinosinusitis. Rhino-manometry showed a remarkable increase in inspiratory nasal flow and a substantial decrease in nasal resistance. No epithelial cell disruption was retrieved comparing pre and post resurfacing samples. Post-diving tubaric dysfunction was found. Pure tone audiometry revealed a bilateral 40 dB HL hearing loss at 4 kHz in 1 diver. Relevant PTA functions did not seem to be affected by the experiment, no remarkable changes were found at the Sensory Organisation Test and at the Motor Control Test. The 14-day underwater period had a positive effect on nasal flows and resistances.

Topics: Adult; Airway Resistance; Audiometry, Pure-Tone; Barotrauma; Diving; Ear, Middle; Epithelial Cells; Female; Hearing Loss; Humans; Italy; Male; Manometry; Nose; Otitis Externa; Otoscopy; Rhinitis; Sinusitis; Time Factors

Topics: Ear Diseases; Endoscopy; Hearing Loss; Humans; Nose; Nose Diseases; Otoscopy; Physical Examination

The objective of this study was to review the various clinical features associated with Wegener's granulomatosis (WG) in the head and neck region and to discuss the difficulty of diagnosing patients with early stage WG.. Between January 1998 and August 2007, WG was diagnosed and treated in 16 patients at the Department of Otolaryngology, Hyogo College of Medicine. Clinical and operating records of these patients were analyzed retrospectively. Diagnosis was based on the Japanese criteria proposed by the Japanese Ministry of Health and Welfare in 1998.. Ten patients (62.5%) had a definite diagnosis of WG, and the other six patients (37.5%) had a probable diagnosis of WG. The period from the onset to diagnosis was between 1 month and 30 years. The generalized form of WG was observed in three patients (18.8%), and the limited form of WG was observed in the other 13 patients (81.2%). Nasal, aural, and ophthalmic symptoms were initially presented in 10, 3, and 3 patients, respectively. Cytoplasmic pattern antineutrophil cytoplasmic antibodies (cANCAs) and perinuclear pattern ANCA (pANCA) were positively detected in 68.8% (11/16) and 27.2% (3/11) of the patients, respectively. Five of 14 patients (35.7%) had pathologic features of WG in biopsy samples from the head and neck region. Three patients in whom a diagnosis of WG was difficult are presented, and immediate lessons of our experience were discussed.. This study emphasized the difficulty of diagnosing WG, particularly at an early stage and when limited to the head and neck region. The biggest challenge faced in diagnosing WG is that it requires a high index of suspicion. When WG was suspected, we should obtain an accurate medical history from patients and repeat serologic and histopathologic examinations.

Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Antibodies, Antineutrophil Cytoplasmic; Blood Sedimentation; C-Reactive Protein; Cerebrospinal Fluid Otorrhea; Cranial Nerve Diseases; Dacryocystitis; Diplopia; Earache; Epistaxis; Exophthalmos; Female; Follow-Up Studies; Granulomatosis with Polyangiitis; Hearing Loss; Humans; Immunosuppressive Agents; Male; Middle Aged; Nasal Obstruction; Nose; Retrospective Studies; Scleritis; Tinnitus; Visual Acuity

Floating-Harbor syndrome is a rare disorder which is clinically characterized by short stature, retarded speech development, delayed bone ages, triangular face, bulbous nose and thin lips. We described two cases with Floating-Harbor syndrome and briefly reviewed the relevant literature.

Topics: Abnormalities, Multiple; Child, Preschool; Craniofacial Abnormalities; Diagnosis, Differential; Dwarfism; Face; Facial Bones; Female; Fingers; Hearing Loss; Heart Septal Defects, Ventricular; Humans; Infant; Intellectual Disability; Male; Mouth Abnormalities; Nose; Pulmonary Valve Stenosis; Speech Disorders; Syndrome

Two new familial cases of Marshall syndrome are reported. The main features of this rare syndrome are outlined. Its possible relationship with Stickler syndrome is discussed.

Topics: Abnormalities, Multiple; Adult; Cataract; Female; Hearing Loss; Hearing Loss, Bilateral; Humans; Infant, Newborn; Male; Myopia; Nose; Pedigree; Syndrome

We report a brother and sister with apparent Johanson-Blizzard syndrome and normal intelligence. There is a wide range of intellectual abilities of persons with Johanson-Blizzard syndrome. No phenotypic predictors of ultimate intellectual function were found in the literature.

Topics: Abnormalities, Multiple; Child, Preschool; Female; Hair; Hearing Loss; Humans; Hypothyroidism; Intelligence; Male; Microcephaly; Nose; Nutrition Disorders

Topics: Child; Eustachian Tube; Hearing Loss; Hearing Loss, Conductive; Humans; Male; Malocclusion; Maxilla; Nose; Palatal Expansion Technique

Topics: Congenital Abnormalities; Deafness; Eyelids; Facial Expression; Genetics, Medical; Hair; Hearing Loss; Humans; Iris; Nose; Nose Deformities, Acquired; Waardenburg Syndrome

Topics: Congenital Abnormalities; Deafness; Eyebrows; Eyelids; Genetics, Medical; Hair; Hearing Loss; Humans; Infant; Infant, Newborn; Iris; Nose; Nose Deformities, Acquired; Pigmentation Disorders; Waardenburg Syndrome

Topics: Child; Deafness; Eye Diseases; Hearing Loss; Humans; Iris; Lacrimal Apparatus; Nose; Nose Deformities, Acquired; Waardenburg Syndrome

Topics: Collagen Diseases; Deafness; Granulomatosis with Polyangiitis; Hearing Loss; Humans; Keratitis; Nose; Paranasal Sinuses; Pharynx

Topics: Albinism; Bone Diseases; Deafness; Genetics, Medical; Hearing Loss; Humans; Iris; Nose; Nose Deformities, Acquired; Waardenburg Syndrome

Topics: Deafness; Eye Abnormalities; Hearing Loss; Humans; Medical Records; Nose; Waardenburg Syndrome

Topics: Child; Constriction, Pathologic; Deafness; Hearing Loss; Humans; Infant; Nose; Nose Diseases

Topics: Deafness; Ear, Inner; Hearing Loss; Hearing Loss, Sudden; Humans; Infections; Nose

Topics: Hearing Disorders; Hearing Loss; Humans; Hypersensitivity; Nose; Nose Diseases

Topics: Deafness; Hearing Loss; Immune Sera; Nose; Otolaryngology

Topics: Deafness; Hearing; Hearing Loss; Hospitals; Humans; New Orleans; Nose