phenylephrine-hydrochloride and Fibrosarcoma

Myxoinflammatory fibroblastic sarcoma (MIFS) is a rare, low-grade, malignant, soft-tissue tumor that typically affects the distal extremities of middle-aged patients. In most cases, it presents as a painless, slowly growing mass within the subcutaneous tissue. It is associated with a low rate of metastasis but a high rate of local recurrence. In addition to the distal extremities, MIFS has been reported in the thigh, arm, forearm, groin, upper back, neck, and temporal area. As far as we know, no case has been previously reported in the nasal area. We report for the first time a case of MIFS presenting on the dorsum of the nose. The painless, 3.0-cm tumor was initially mistaken for reticular erythematous mucinosis, a benign skin condition that occurs when fibroblasts produce abnormally large amounts of mucopolysaccharides. The tumor was surgically removed in its entirety with surgical margins of 3 to 5 mm. During 4 years of follow-up, no clinical or radiologic evidence of a recurrence or metastasis was seen. We discuss the imaging and histologic features of MIFS, as well as its clinical management and follow-up, and we review related reports in the literature.

Topics: Fibrosarcoma; Humans; Male; Middle Aged; Myxoma; Nose; Nose Neoplasms

A 9-year-old domestic shorthair cat was referred for removal of a rostrally located fibrosarcoma on the face, which had previously recurred twice following excision. A wide excision was performed, using a neodymium:yttrium-aluminumgarnet (Nd:YAG) laser, resulting in a facial defect that could not be closed by primary suture. An interpolation skin flap was elevated, using skin from the side of the cat's face, and sutured in place over the defect. Recurrence of the tumor at the medial canthus of the left eye, which was observed 4 months after surgery, was treated by laser excision and cryotherapy. Other recurrences of the fibrosarcoma were not noticed for 2.5 years after referral, at which time the cat was euthanatized for other reasons. Necropsy revealed that the fibrosarcoma had not recurred. In this cat, an interpolation skin flap was useful in repairing a large rostral facial defect. Care should be taken when elevating this flap to preserve the palpebral nerve.

Topics: Animals; Cat Diseases; Cats; Facial Neoplasms; Female; Fibrosarcoma; Laser Therapy; Neoplasm Recurrence, Local; Nose; Postoperative Complications; Surgical Flaps

Topics: Adolescent; Adult; Carcinoma, Squamous Cell; Cheek; Child; Face; Facial Neoplasms; Female; Fibrosarcoma; Fistula; Humans; Male; Melanoma; Middle Aged; Mouth Neoplasms; Nose; Nose Deformities, Acquired; Surgical Flaps

Topics: Aged; Fibrosarcoma; Humans; Male; Nasal Cavity; Nose; Nose Neoplasms

Topics: Acne Vulgaris; Adult; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Facial Neoplasms; Female; Fibrosarcoma; Follow-Up Studies; Humans; Lymphoma; Neoplasm Recurrence, Local; Neoplasms, Radiation-Induced; Nose; Skin Transplantation; Surgery, Plastic; Transplantation, Autologous

Topics: Fibrosarcoma; Humans; Medical Records; Nasal Cavity; Neoplasms; Nose; Paranasal Sinus Neoplasms

Topics: Fibrosarcoma; Humans; Nasal Cavity; Nose; Sarcoma