phenylephrine-hydrochloride and Facial-Dermatoses

Conidiobolomycosis is an uncommon, chronic, localized subcutaneous mycosis primarily affecting rhinofacial region. It is reported mainly from tropical and subtropical countries. The condition is underreported due to the lack of clinical suspicion and usually mismanaged. This rare mycosis is due to the genus

Topics: Adolescent; Adult; Aged; Antifungal Agents; Conidiobolus; Dermatomycoses; Facial Dermatoses; Humans; Male; Nose; Zygomycosis

Granuloma faciale (GF) is an uncommon inflammatory dermatosis that usually presents on the face as reddish brown or violaceous papules and nodules that may coalesce into plaques. Eosinophilic angiocentric fibrosis (EAF) is a rare fibrosing condition that shares many histologic characteristics with GF and is regarded by some authors as a mucosal counterpart of GF. We present a case of GF with concurrent EAF in a subglottic location with excellent response to an intralesional corticosteroid on the GF lesion, CO2 laser on the EAF lesion, and oral dapsone treatment.

Topics: Aged; Dapsone; Eosinophilia; Facial Dermatoses; Fibrosis; Glucocorticoids; Granuloma; Humans; Injections, Intralesional; Larynx; Lasers, Gas; Male; Nose

Coccidiodomycosis is a systemic infection caused by Coccidioides immitis, a dimorphic fungus endemic in the south of the USA and the north of Mexico. The disease usually affects the lungs. Primary cutaneous infection is extremely rare. We present a report of a patient with primary cutaneous infection located on the nose. To our knowledge, such a presentation has never previously been reported in the literature.. The patient had a 3-cm-diameter elevated nodule with a verrucous aspect located on the tip of her nose. The histopathologic features of the lesion were consistent with coccidioidomycosis.. To our knowledge, this is the first report of primary cutaneous coccidioidomycosis located on the tip of nose.

Topics: Adult; Antifungal Agents; Coccidioidomycosis; Facial Dermatoses; Female; Humans; Itraconazole; Nose

Feline herpesvirus-associated dermatitis has rarely been reported. Recently we documented a unique ulcerative and often persistent facial dermatitis or stomatitis syndrome associated with feline herpesvirus 1. We believe this syndrome is relatively common, with the 10 cases in our series diagnosed between 1996 and 1997. The syndrome is associated with epithelial cell necrosis, eosinophilic inflammation, and intraepithelial herpesvirus inclusion bodies. The prevalence of eosinophilic inflammation and low number of inclusion bodies may lead to the misdiagnosis of allergic dermatitis or a lesion within the eosinophilic granuloma complex group of disorders. Feline herpesvirus 1 can be identified in lesional tissue by PCR methodology. Most of our cases developed under circumstances suggesting reactivation of latent herpesvirus infection, and previous glucocorticoid therapy or stress from overcrowding may have played a role in lesion development. Cats with ulcerative dermatitis, especially of the face and nose, and cats with stomatitis should be evaluated for the presence of feline herpesvirus. Treatment options include surgical excision, topical or systemic antibiotic therapy to treat secondary bacterial infection, and oral alpha interferon.

Topics: Alphaherpesvirinae; Animals; Animals, Domestic; Cat Diseases; Cats; Diagnosis, Differential; Facial Dermatoses; Herpesviridae Infections; Nose; Stomatitis

The use of noninvasive ventilation masks is known to cause damage to facial skin tissue, which affects both the efficacy of the intervention and the patient's quality of life. The use of humidification with noninvasive ventilation is a common practice, but its relative role in the development of facial pressure ulcers has not been fully studied.. A crossover cohort design was used in this study, with 15 healthy volunteers. Each volunteer randomly received both 10 cm H. Humidified CPAP significantly increased transepidermal water loss (. These findings indicated that noninvasive ventilation with humidification had a potential disrupting effect on the barrier function of facial skin, associated with changes in skin microclimate and function. Further research is required to establish the cause of mask-related skin damage and to evaluate the effects of mask design, application techniques, and air flow and humidity settings.

Topics: Adult; Continuous Positive Airway Pressure; Cross-Over Studies; Face; Facial Dermatoses; Female; Healthy Volunteers; Humans; Humidity; Hydrogen-Ion Concentration; Interleukin-1alpha; Male; Masks; Noninvasive Ventilation; Nose; Organism Hydration Status; Pressure Ulcer; Quality of Life; Skin; Surgical Tape

Pigmented transverse nasal band (PTNB) is an interesting morphological entity mainly of cosmetic concern. It is believed to be related to a defect in the development of the nasal cartilages and bones from childhood to adolescence. Some patients may have genetic predisposition. It is asymptomatic in nature and may be associated with certain dermatological conditions such as seborrheic diathesis, dermatosis papulosa nigra, ichthyosis, atopic dermatitis, acne vulgaris, psoriasis, and seborrheic melanosis.

Topics: Facial Dermatoses; Female; Humans; Hyperpigmentation; Nose; Young Adult

Topics: Facial Dermatoses; Humans; Male; Middle Aged; Nose; Pemphigus

Topics: Air Pollutants, Occupational; Dermatitis, Allergic Contact; Dermatitis, Occupational; Eyelids; Facial Dermatoses; Humans; Lip; Male; Middle Aged; Neck; Nose; Occupational Exposure; Sulfonamides

Topics: Aged, 80 and over; Cheek; Diagnosis, Differential; Facial Dermatoses; Female; Forearm; Humans; Lichenoid Eruptions; Nose; Sarcoidosis

Topics: Administration, Cutaneous; Aged; Facial Dermatoses; Farmers; Humans; Keratolytic Agents; Male; Nose; Skin; Sunlight; Treatment Outcome; Tretinoin

Topics: Acne Vulgaris; Child; Dermoscopy; Facial Dermatoses; Female; Humans; Hypopigmentation; Keratosis; Nose; Skin

Rosacea is characterized by erythema on face, especially erythema and linear telangiectasia on the nose. Currently, various vascular lasers are used for treatment, and among them, are long-pulsed Nd:YAG(LPNY) and pulsed dye laser (PDL).. This study compared the efficacy of LPNY and PDL in treating rosacea-associated nasal telangiectasia.. Patients with rosacea who showed erythema and telangiectasia on the nose were included. Each patient was treated with PDL on the left side of the nasal bridge, and LPNY on the right side, three times with 4-week intervals. At the end of the treatment, two independent dermatologists evaluated overall treatment response compared with baseline.. The physician's assessment of treatment concluded that good improvement was seen in six PDL and seven LPNY patients, and excellent improvement five PDL and four LPNY patients. There was no significant difference (p = 0.62, 95%CI) between the groups. Overall improvement was similar; however, LPNY induced a greater response in thick, dilated vessels, while erythema with mild telangiectasia was more responsive to PDL.. Both LPNY and PDL are effective in treating rosacea-associated nasal telangiectasia. If LPNY is used properly to avoid side effects with careful consideration, it can also be used as a good modality.

Topics: Adult; Aged; Erythema; Facial Dermatoses; Female; Humans; Lasers, Dye; Lasers, Solid-State; Low-Level Light Therapy; Male; Middle Aged; Nose; Rosacea; Telangiectasis; Treatment Outcome

Topics: Aged; Autoimmune Diseases; Autoimmunity; Biomarkers; Biopsy; Facial Dermatoses; Glucocorticoids; Humans; Immunoglobulin G; Immunohistochemistry; Male; Nose; Remission Induction; Skin; Treatment Outcome

Rosacea fulminans is a rare disorder of unknown cause, almost exclusively affecting women. There are only a few reported cases in men. The condition is characterized by the abrupt onset of pustules and nodules predominantly affecting the cheeks or chin without any systemic upset. We report the case of a 37-year-old man who presented with papulopustules, predominantly localized to his nose. Histopathological features were consistent with rosacea fulminans. The patient was managed with treatments including oral prednisolone, isotretinoin, and trimethioprim.

Topics: Adult; Anti-Infective Agents; Anti-Inflammatory Agents; Dermatologic Agents; Drug Therapy, Combination; Facial Dermatoses; Humans; Isotretinoin; Male; Nose; Prednisolone; Rosacea; Trimethoprim

Topics: Child; Diagnosis, Differential; Facial Dermatoses; Herpes Simplex; Humans; Hydroa Vacciniforme; Male; Mouth; Nose; Recurrence

Topics: Adult; Facial Dermatoses; Humans; Lymph Nodes; Lymphatic Diseases; Male; Nose; Nose Diseases; Recurrence; Sarcoidosis; Stomach Diseases

Many environmental acne disorders, including chloracne and oil acne, were previously thought to occur predominantly in occupational settings following polycyclic aromatic hydrocarbon exposure. Cigarette smoke has also been shown to contain a large number of these toxic polycyclic aromatic hydrocarbon components and strictly correlates with noninflammatory acneiform lesion development in postadolescent patients. We report a case of localized open comedones associated with occluded cigarette smoke exposure near the nasal cavity due to infrequently changed gauze following rhinectomy. The dermal uptake of polycyclic aromatic hydrocarbon components in cigarette smoke has the potential to function as a contributing factor in chloracne development. Several of these environmental and noninflammatory acne subtypes may share a common molecular propensity for enhanced comedogenesis originating from aryl hydrocarbon receptor pathway effects in the skin. Additional studies are needed to further elucidate the exact mechanistic pathways through which tobacco smoke impacts the integumentary system.

Topics: Animals; Bandages; Chloracne; Facial Dermatoses; Humans; Male; Middle Aged; Nose; Smoke; Tobacco Products

Topics: Facial Dermatoses; Female; Humans; Middle Aged; Nose; Rosacea; Sporotrichosis

Topics: Aged; Antineoplastic Agents; Docetaxel; Facial Dermatoses; Humans; Incidental Findings; Male; Middle Aged; Nose; Nose Diseases; Recurrence; Remission, Spontaneous; Rosacea; Taxoids; Telangiectasis

Topics: Aged; Chlorides; Dermabrasion; Drug Eruptions; Facial Dermatoses; Female; Ferric Compounds; Hemostatics; Humans; Nose; Pigmentation Disorders; Salts

Topics: Body Piercing; Chronic Disease; Erythema; Facial Dermatoses; Female; Humans; Nose; Telangiectasis; Young Adult

Topics: Aged; Facial Dermatoses; Humans; Male; Muscle Relaxants, Central; Nose; Pigmentation Disorders; Quinine

Subcutaneous phaeohyphomycosis is the most common variety of phaeohyphomycosis and presents as asymptomatic or mildly painful, localized cysts, abscesses, or sometimes chromoblastomycosis-like lesions over the feet, legs, or hands in about 60-85% of cases. It usually afflicts adults with some degree of immunosuppression.. We report a 30-year-old man, who presented with features of recurrent sinusitis (episodes of fever, nasal stuffiness, paranasal sinus pain, and tenderness), mucosal hypertrophy of the maxillary sinuses, and mid-face swelling that was freely mobile and suggestive of rhinoentomophthoramycosis. He had no other associated illness.. Histology suggested tumid lupus erythematosus. The diagnosis was based on Fonsecaea pedrosoi cultured from a biopsy specimen.. Combination therapy with itraconazole and saturated solution of potassium iodide (SSKI) was more effective than itraconazole used alone.

Topics: Adult; Antifungal Agents; Ascomycota; Drug Therapy, Combination; Facial Dermatoses; Humans; Itraconazole; Male; Nose; Orbit; Phaeohyphomycosis; Potassium Iodide

Topics: Facial Dermatoses; Famous Persons; History, 20th Century; Humans; Nose

Fibrous papules of the face are frequent benign lesions seen in the nasal and perinasal region. Their clinical aspect is indistinct and the histological signs are sometimes mild or possibly misleading in the case of atypical forms. We carried out a retrospective study of 283 fibrous papules diagnosed at our histology laboratory. The goal of this study was to characterize this type of frequent but occasionally unrecognized lesion.. We performed a retrospective study of fibrous papules of the face diagnosed in the dermatopathology laboratory of our dermatology centre between January 2002 and December 2011. The study concerned the clinical information noted in the examination request and the morphological abnormalities seen at optical microscopy. An immunohistological study of factor XIIIa was performed in selected cases.. The fibrous papules of the face came from 129 men and 154 women aged between 18 and 90 years (mean: 46 years). Two hundred and thirty-seven (83.7%) lesions were taken from the nasal region and none were taken from anywhere other than the face. The clinically mentioned diagnoses varied. A diagnosis of fibrous papule of the face was stated in 42% of cases, and the main differential diagnoses were nevus (stated in 34% of cases) and basal cell carcinoma (stated in 14% of cases). The fibrous papules were classic in 85.5% of cases. We observed 6 variants of fibrous papule: hypercellular, inflammatory, pleomorphic, pigmented, clear-cell and granular-cell types. Immunohistochemistry of factor XIIIa was positive in all cases except clear-cell fibrous papules.. This study shows that despite their frequency, these lesions often go unrecognized, since the hypothesis of a fibrous papule of the face was mentioned in fewer than 50% of cases at the time of biopsy. Diagnosis is often made by the histopathologist, who may be misled by some rare types. The principal differential diagnoses are nevus and basal cell carcinoma, thus warranting methodical histological analysis of all pieces.

Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Carcinoma, Basal Cell; Collagen; Diagnosis, Differential; Facial Dermatoses; Factor XIIIa; Female; Fibrosis; France; Humans; Male; Middle Aged; Nevus; Nose; Retrospective Studies; Skin Diseases, Papulosquamous; Skin Neoplasms; Staining and Labeling; Young Adult

CME EDUCATIONAL OBJECTIVES1.Recognize the transverse nasal crease and its association.2.Identify treatment options for milia in the nasal crease.3.Identify cutaneous findings associated with atopy in children. An 8-year-old male presented for evaluation of a lesion across his nasal bridge. This had been worsening and getting more prominent over the last 6 months. He frequently rubbed his nose with the palm of his hand due to rhinitis. His medical history was significant for asthma, allergic rhinitis, conjunctivitis, and resolved peanut allergy. He lived with his parents and was the youngest of five children. The boy's family history was significant for atopy in parents, and a sister with anaphylaxis to tree nuts. There was no family history of severe or scarring acne vulgaris. Review of systems was normal.

Topics: Child; Facial Dermatoses; Humans; Male; Nose; Rhinitis, Allergic, Perennial

Before undergoing a reconstructive procedures of the nose most patients ask how they will look postoperatively. Anthropometric measurements of the nose described by Farkas represent standard values. A comparison of pre- and postoperative anthropometric measurements may help to double-check the correctness of intraoperative "eye-balling" measurements with regards to postoperative appearance. Sixty-three patients underwent reconstruction of nasal ala, tip or dorsum. An analysis of standardized pre- and postoperative photographs included measurements of nose width, nose height, nasal tip protrusion, columella width, ala length, intercanthal width, mouth width, philtrum width, upper lip height, lateral upper lip height, cutaneous upper lip height and upper face height. Preoperative measurements were compared to data given by Farkas in young adults. Postoperative changes were evaluated clearly distinguishing between reconstruction of nasal ala, tip and dorsum. All anthropometric indices showed significant differences compared to the Farkas population. There was no significant pre- to postoperative change in any reconstructed region observed, indicating adequate intraoperative measurements. The application of Farkas' anthropometric measurements described in this study showed reliable and objective results and can help to double-check the previous intraoperative measurements. The correct application of these surgical techniques leads to a satisfying and near to normal postoperative look of the patient.

Topics: Adolescent; Aged; Anatomic Landmarks; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cephalometry; Facial Dermatoses; Female; Humans; Lip; Male; Nasal Cartilages; Nose; Nose Diseases; Nose Neoplasms; Photography; Plastic Surgery Procedures; Reproducibility of Results; Surgical Flaps; Treatment Outcome; Vertical Dimension

Topics: Adult; Biopsy; Diagnosis, Differential; Facial Dermatoses; Facial Neoplasms; Female; Folliculitis; Humans; Nose; Pseudolymphoma

Topics: Biopsy; Eosinophilia; Facial Dermatoses; Fibrosis; Granuloma; Humans; Male; Middle Aged; Nasal Obstruction; Nose

Topics: Adult; Chronic Disease; Facial Dermatoses; Female; Humans; Lateral Medullary Syndrome; Nose; Skin Ulcer; Trigeminal Nerve Diseases

We report the epidemiological and clinical characteristics of the erysipeloid form of cutaneous leishmaniasis as well as its diagnostic and therapeutic challenges.. A 63-year-old woman, with no medical history, presented with a one-month history of erythematous nasal swelling. The lesion appeared after an accidental trauma. Erythematous infiltrative plaque was noted on the center of the face. There were also crust formations on the traumatic region. Despite local treatment and oral antibiotherapy, there was no improvement. The diagnosis of cutaneous leishmaniasis was confirmed by positive skin smears. Histopathological examinations of a skin biopsy showed no malignancy. The patient was treated intramuscularly with 10mg/kg per day systemic meglumine antimoniate with partial regression of symptoms.. The erysipeloid type is a rare and unusual presentation of cutaneous leishmaniasis that often causes late diagnosis. Diagnosis is confirmed by the demonstration of the parasite by skin smear, histopathological examination and polymerase chain reaction. There are various therapeutic options. The evolution is generally favourable.

Topics: Antiprotozoal Agents; Biopsy; Diagnosis, Differential; Erysipeloid; Facial Dermatoses; Female; Humans; Leishmaniasis, Cutaneous; Meglumine; Meglumine Antimoniate; Middle Aged; Nose; Nose Diseases; Organometallic Compounds; Polymerase Chain Reaction; Skin

The diagnosis of pigmented actinic keratosis can be complicated in clinical practice. The differential diagnosis with lentigo maligna melanoma can be difficult due to common clinical and dermoscopic characteristics. We present 5 cases of pigmented actinic keratosis in 4 patients. The most common dermoscopic finding was a grayish-brown granulation with a perifollicular distribution, present in all lesions, followed by rhomboidal structures in 4 cases, and an annular-granular pattern in 3. In no case were asymmetrical pigmented follicular openings observed. We draw attention to key findings that aid preoperative diagnosis of pigmented actinic keratosis.

Topics: Aged; Aged, 80 and over; Dermoscopy; Diagnosis, Differential; Epidermis; Facial Dermatoses; Female; Humans; Hutchinson's Melanotic Freckle; Keratinocytes; Keratosis, Actinic; Male; Melanins; Middle Aged; Nose; Skin Pigmentation

A 45-year-old male presented with a 6 month history of an enlarging smooth, erythematous plaque over the central part of his face. Mild erythema of both eyes was present. Sarcoidosis, Hansen disease, lupus vulgaris, cutaneous leishmaniasis, pseudolymphoma, foreign body granuloma, granuloma faciale, discoid lupus erythematosus, and granulomatous rosacea were considered in the differential diagnosis. CBC, urinalysis, renal function tests, liver function tests, serum electrolytes, and blood sugar were all normal. Chest X-ray and ECG revealed no abnormality. Serology for syphilis and HIV, and mantoux test were negative. Slit-skin smear, tissue smear and culture for AFB and fungi were negative. Skin biopsy revealed multiple non-caseating epitheloid granulomas around the pilosebaceous unit suggestive of granulomatous rosacea. Granulomatous rosacea, a rare entity comprising only about 10 percent of cases of rosacea can mimic many granulomatous conditions both clinically and histologically making the diagnosis an enigma. It usually presents as yellowish brown-red discrete papules on the face; non-caseating epithelioid granulomas are seen on histology examination. We herein report the case because it presented in atypical fashion, as a solitary indurated plaque on the nose, likely representing Morbihan's disease or solid persistent facial edema of rosacea (rosacea lymphedema).

Topics: Anti-Inflammatory Agents; Dermatologic Agents; Diagnosis, Differential; Facial Dermatoses; Humans; Isotretinoin; Male; Middle Aged; Nose; Prednisolone; Rosacea

Topics: Accidental Falls; Aged; Biopsy; Facial Dermatoses; Facial Injuries; Female; Humans; Immunocompetence; Mycobacterium tuberculosis; Nose; Skin Ulcer; Tuberculosis, Cutaneous; Wound Infection

A positive Hutchinson's sign indicates an increased risk of ocular involvement in herpes zoster ophthalmicus (HZO). We examined the sensitivity of Hutchinson's sign as an indicator of ocular involvement in a consecutive series of patients presenting with HZO.. We conducted a descriptive observational prospective study of patients > or =18 years old presenting with HZO and consenting to pre-and post-test counselling and HIV and CD4 testing. A full ophthalmological examination focused on the extent of ocular involvement, and the presence of Hutchinson's sign was confirmed by two clinicians.. Thirty-three patients were enrolled; 29 were HIV positive, of whom 18 (62%) had not been diagnosed with HIV prior to enrollment. Of the 29 HIV-positive patients, 21 (72%) were Hutchinson's sign positive (HSP), all of whom had intra-ocular involvement (95% confidence interval 88 - 100%). Of the 8 HIV-positive, Hutchinson's sign-negative (HSN) patients, 4 did and 4 did not display intra-ocular involvement. Neither the mean CD4 count nor the average age in the HSP group differed significantly from the HSN group.. We confirmed that a Hutchinson's sign- and HIV-positive patient with HZO has a very high positive predictive value for intra-ocular involvement. Neither age nor CD4 count had predictive value for ocular involvement. Young adults presenting with HZO should be suspected of having HIV, and HIV-positive patients with HZO but HSN may still have ocular involvement. All patients with HZO should be seen by an ophthalmologist.

Topics: Adult; Case-Control Studies; CD4 Lymphocyte Count; Cohort Studies; Facial Dermatoses; Female; Herpes Zoster Ophthalmicus; HIV Infections; Humans; Male; Middle Aged; Nose; Predictive Value of Tests; Reproducibility of Results; Skin Diseases, Vesiculobullous; Young Adult

Currently, there is no gold standard for the treatment of enlarged facial pores. In this report, we describe a patient with enlarged nasal pores which were treated with a combination of a non-ablative 1450-nm diode laser, a Q-switched and quasi long-pulsed 1064-nm Nd:YAG laser, and an ablative 10 600-nm carbon dioxide fractional laser system. Four months after the final treatment, the condition of the patient's pores had markedly improved, and the patient was satisfied with the results.

Topics: Adult; Combined Modality Therapy; Esthetics; Facial Dermatoses; Follow-Up Studies; Humans; Lasers, Gas; Lasers, Semiconductor; Lasers, Solid-State; Low-Level Light Therapy; Male; Nose; Risk Assessment; Treatment Outcome

Topics: Dermatitis; Facial Dermatoses; Factitious Disorders; Female; Humans; Middle Aged; Nose; Skin Ulcer

Topics: Adult; Cryoglobulinemia; Ear, External; Facial Dermatoses; Humans; Immunoglobulin G; Male; Multiple Myeloma; Nose; Skin Diseases

Topics: Adolescent; Botulinum Toxins, Type A; Facial Dermatoses; Humans; Hyperhidrosis; Male; Nose

Topics: Diagnosis, Differential; Diagnostic Errors; Facial Dermatoses; Humans; Male; Middle Aged; Nose; Pemphigus

An 18-year-old man presented with erythematous lesions over the nose of 1 year's duration without sensitivity to sunlight. He was otherwise well and there was no relevant family history. Physical examination showed excessive sweating of the nose, cheeks, and upper lip, and erythema of the nose covered by beads of sweat and vesicles (Fig. 1). The rest of the physical examination was normal. The skin biopsy showed a discrete mononuclear cell perivascular infiltrate.

Topics: Adolescent; Diagnosis, Differential; Erythema; Facial Dermatoses; Granulomatous Disease, Chronic; Humans; Male; Nose; Skin Diseases, Vesiculobullous

Wrinkle reduction and the correction of skin defects using injectable aesthetic microimplants are now widely performed by dermatologists and plastic surgeons. In recent years, dermal filler substances containing polymer particle suspensions such as Bioplastique, Artecoll, and Dermalive are the most commonly used materials. These microimplants are permanent, non-biodegradable, and generally well tolerated, although various adverse reactions are still possible. We describe here a patient with facial granulomas secondary to Dermalive injections for correction of naso-labial folds and wrinkles. The particular shape of the injected particles allows for correct identification of the implanted material. Therefore, histopathologic examination is the best means to obtain the correct diagnosis of foreign body granuloma and to identify the type of filler particles. We discuss the histopathologic differential diagnosis among the granulomas secondary to the most commonly used aesthetic permanent filler materials.

Topics: Acrylates; Biocompatible Materials; Cosmetic Techniques; Diagnosis, Differential; Facial Dermatoses; Female; Granuloma, Foreign-Body; Humans; Hyaluronic Acid; Hydrogels; Injections, Intradermal; Lip; Middle Aged; Nose; Skin Aging

Topics: Diagnosis, Differential; Facial Dermatoses; Female; Humans; Middle Aged; Nose; Sarcoidosis

Topics: Aged; Color; Facial Dermatoses; Female; Hair; Humans; Nose

Topics: Adult; Facial Dermatoses; Humans; Hyperplasia; Male; Nose; Puberty; Sebaceous Glands

Canine discoid lupus erythematosus (DLE) and mucocutaneous pyoderma (MCP) have overlapping clinical and histopathological changes, often making diagnosis difficult. Histopathological features of 27 nasal planum biopsies were scored to determine whether DLE and MCP were histopathologically distinguishable. Long-term follow-up, enabling assessment of clinical diagnoses, was available on 15 cases; 11/15 cases were immunomodulatory responsive (ImR) and 4/15 were antibiotic responsive (AbR). Clinical diagnosis, determined by response to treatment for 15/27 cases, was not predictable based on scoring of histopathological features. Distinct histopathological patterns were observed: 2/11 ImR cases had a lymphocyte-rich interface dermatitis. All other cases had the same histopathological changes: a band-like diffuse superficial plasmacytic to lymphoplasmacytic dermatitis +/- focal basal cell damage, but different clinical diagnoses (4/4 AbR, 9/11 ImR). German shepherd dogs/crosses were over-represented (44.4% of the cases) and tended to have more multifocal lesions (41.7% vs. 26.7% of all other breeds). Longer duration of disease was associated with a preponderance of plasmacytic infiltrate (P = 0.026).

Topics: Animals; Anti-Bacterial Agents; Dog Diseases; Dogs; Facial Dermatoses; Female; Immunologic Factors; Lupus Erythematosus, Discoid; Male; Nose; Pyoderma; Retrospective Studies

Eosinophilic pustular folliculitis (EPF) (Ofuji's disease) is a rare dermatosis of unknown etiology. We describe a 45-year-old Chinese woman who developed EPF on her face seven years after having nose and chin augmentation with subcutaneous silicone injections.

Topics: Chin; Diagnosis, Differential; Facial Dermatoses; Female; Folliculitis; Humans; Middle Aged; Nose; Silicones; Surgery, Plastic

Treatment of warts can involve medical and surgical methods. Infrared coagulation is a surgical method very rarely used in the treatment of warts. We planned an open-labeled prospective study to research the effect of infrared coagulation in the treatment of common warts, comparing it with electrocoagulation, and discussing its applicability as an alternative therapy regimen. Eighteen patients with common warts were included in this study. There were 49 warts of various sizes (1 mm to 1 cm) in these 18 patients. Twenty-seven warts were treated with infrared coagulation, and 22 warts were treated with electrocoagulation. Sixteen patients were treated with both infrared coagulation and electrocoagulation; two patients were treated with only infrared coagulation. The patients were followed-up for six months after treatment. Changes in sizes of warts, healing times, and cure rates were compared by Mann-Whitney U test. The mean healing time was 35.5 +/- 5.7 days with infrared coagulation and 32.9 +/- 4.0 days with electrocoagulation. There was not any significant difference between healing times (p > 0.05). Bacterial infection was seen on seven (31.8%) warts treated with electrocoagulation, but no side effects were seen with infrared coagulation. There was a significant difference between side effect rates in two groups (p < 0.01). Nine (33.3%) of the warts treated with infrared coagulation and seven (31.8%) of the warts treated with electrocoagulation recurred in the six-month follow-up period. The overall cure rates at the end of the follow-up period were 66.7% and 68.2% respectively. There was not any significant difference between the cure rates in the two groups (P > 0.05). We conclude that infrared coagulation is a safe and cheap method and should be kept in mind as an alternative modality for the treatment of common warts.

Topics: Adolescent; Adult; Electrocoagulation; Facial Dermatoses; Female; Foot Dermatoses; Hand Dermatoses; Humans; Infrared Rays; Light Coagulation; Male; Middle Aged; Nose; Prospective Studies; Treatment Outcome; Warts

Topics: Blister; Facial Dermatoses; Female; Humans; Middle Aged; Nevus; Nose; Radiation Injuries; Radiotherapy; Recurrence

Topics: Aged, 80 and over; Cheek; Facial Dermatoses; Humans; Male; Nose; Pemphigus; Scalp; Skin Ulcer

Topics: Anti-Bacterial Agents; Diagnosis, Differential; Drug Therapy, Combination; Facial Dermatoses; Humans; Male; Middle Aged; Niacinamide; Nose; Pemphigus; Tetracycline

Topics: Aged; Blastomycosis; Facial Dermatoses; Humans; Lip; Male; Nose

Topics: Acrylates; Acrylic Resins; Adhesives; Adult; Allergens; Dermatitis, Allergic Contact; Dermatitis, Occupational; Diagnosis, Differential; Eyelids; Facial Dermatoses; Female; Hand Dermatoses; Humans; Nose; Patch Tests

Ectodermal dysplasia (ED) is an inherited disorder in which two or more ectodermally derived structures fail to develop, or are abnormal in development. Hypohydrotic ectodermal dysplasia (HED) or Christ-Siemens-Touraine syndrome, is an X-linked recessive syndrome with an incidence of 1/10,000 to 1/100,000 births. Because of its X-linked inheritance pattern, it is more common in males. HED is characterised by hypohydrosis (diminished perspiration), hypotrichosis (decreased amount of hair) and microdontia (small teeth), hypodontia (lack of development of one or more teeth) or adontia (total lack of tooth development). These patients present diagnostic and treatment challenges because of variable oral manifestations. This report describes an 11-year-old Xhosa boy, who was referred to the University Dental Faculty by his general medical practitioner because of hypodontia. General facial features included: frontal bossing, a depressed nasal bridge, 'butterfly' pattern of eczema over the nasal bridge to the malar process of each cheek, thinned out hair, loss of vertical dimension of face and dry skin. Intra-oral examination revealed hypodontia with peg-shaped anterior teeth and diastemas. Radiological examination revealed no developing permanent teeth or tooth buds. Diagnosis was confirmed by doing a sweat gland count. Management included oral hygiene instruction, fluoride treatments, construction of a partial lower denture and counselling about his condition with particular reference to the danger of hyperthermia and control of allergies.

Topics: Anodontia; Child; Diastema; Ectodermal Dysplasia; Eczema; Facial Dermatoses; Frontal Bone; Genetic Diseases, X-Linked; Hair; Humans; Male; Nose; Tooth, Deciduous

A seventeen-year-old Korean girl had a reddish-brown papular lesion on the nose. Histopathologically, it proved to be a "hyalinizing Spitz nevus" with the characteristic features of a discohesive growth pattern of nevus cells and hyalinized stroma. Immunohistochemical stains showed positive reactivity of nevus cells with S-100 protein and Vimentin and negative stainings with HMB45, CD68, CEA and low molecular weight cytokeratin. Hyalinizing Spitz nevus may represent a variant in the spectrum of Spitz nevus.

Topics: Adolescent; Facial Dermatoses; Female; Humans; Hyalin; Immunohistochemistry; Nevus, Epithelioid and Spindle Cell; Nose; Skin Neoplasms

We report four children with linear eruptions on the nose, with overlapping features of lichen striatus and linear cutaneous lupus erythematosus. However, linear lupus erythematosus has rarely been reported, and lichen striatus, although classically linear, rarely affects the face. The linear distribution of lesions from the glabella to the ala nasi may represent distribution following Blaschko's lines.

Topics: Adolescent; Biopsy; Child, Preschool; Diagnosis, Differential; Facial Dermatoses; Female; Humans; Infant; Lichenoid Eruptions; Lupus Erythematosus, Cutaneous; Male; Nose

We report a case of a 38-year-old female patient who developed facial cellulitis after cord-blood stem cell transplantation (CBT). The cellulitis was refractory to treatment with antibiotics and antifungal agents. Because facial cellulitis is rare after transplantation, its mechanism could not be determined exactly. On day 40 after CBT, a nurse with expertise in cosmetic surgery attended our rounds and correctly assumed that the patient had received cosmetic rhinoplasty. Although conventional x-rays of the head were normal, a computed tomographic (CT) scan of the brain disclosed the presence of a foreign body over the nasal dorsum. As a result, the patient's symptoms were diagnosed as facial cellulitis associated with foreign material that had been implanted at the time of cosmetic surgery. At a pretransplantation interview, the patient did not mention her history of rhinoplasty. Even after she was shown the head CT scans that revealed the presence of nasal implants, she denied that she had received rhinoplasty before CBT. Unless we realize that patients may have received cosmetic surgery before transplantation, it is difficult to make a diagnosis of infection associated with foreign implants. To our knowledge this is the first report after transplantation of infection associated with cosmetic surgery. Such infections should be included on the list of complications after bone marrow transplantation.

Topics: Adult; Cellulitis; Facial Dermatoses; Female; Fetal Blood; Foreign-Body Reaction; Hematopoietic Stem Cell Transplantation; Humans; Nose; Rhinoplasty; Surgical Wound Infection; Transplantation Conditioning

Evaluation of silicone-induced morbidity in skin has been hampered by the difficulty of detecting silicone in tissue because conventional methods are nonquantitative and insensitive.. We attempted to determine whether silicone could be identified and quantitated in skin by means of electron spectroscopy for chemical analysis (ESCA).. Skin biopsy specimens were obtained from the nose, chin, malar region, and inner arm of a patient who had received injections of silicone gel in his nose and chin. Frozen sections were dried under vacuum and examined by means of ESCA. Contiguous sections were examined by light microscopy.. The surface concentrations of silicone were as follows: chin, 20.6% +/- 3.6%; nose, 19.0%; malar region, 2.6% +/- 1.6%; inner arm, 0.0% +/- 0.0%. Light microscopy revealed homogeneous "globules" consistent with silicone in the chin and nose sections only; the malar region and inner arm sections showed no evidence of silicone.. ESCA can be used to detect silicone in skin in a specific, highly sensitive, and quantitative manner. This is the first report of quantification of silicone in skin by means of ESCA.

Topics: Arm; Cheek; Chin; Dermis; Electron Probe Microanalysis; Facial Dermatoses; Frozen Sections; Histiocytes; Humans; Lymphocytes; Male; Middle Aged; Nose; Silicone Gels; Skin; Vacuum

Cutaneous benign lymphoid hyperplasia is a B-cell pseudolymphoma of unknown origin. The most favored sites of involvement include the face. We report two cases involving the nose that showed complete and stable regression after a 2-month treatment course with thalidomide.

Topics: Adolescent; Adult; B-Lymphocytes; Dermatologic Agents; Facial Dermatoses; Female; Humans; Male; Nose; Pseudolymphoma; Thalidomide

We report a patient with massive facial sarcoidosis. While skin involvement is a common manifestation of sarcoidosis, it is unusual to see it in the dramatic form of cutaneous tumors with mutilation of the central face. There are few reports of tumoral cutaneous sarcoidosis like that of our patient.

Topics: Adult; Facial Dermatoses; Female; Humans; Nose; Orbital Neoplasms; Sarcoidosis; Skin Neoplasms

Topics: Adult; Conjunctival Diseases; Facial Dermatoses; Female; Humans; Nose; Pseudolymphoma

Topics: Facial Dermatoses; Gram-Positive Bacterial Infections; Humans; Male; Middle Aged; Nose; Propionibacterium acnes; Skin Diseases, Bacterial

Seven cases of trigeminal trophic syndrome are reported. In this rare condition, neurotrophic ulcers occur on the face, especially in the ala nasi area in a dermatome of the trigeminal nerve that has been rendered anesthetic, usually as a complication of trigeminal ablation by surgical means or injection for treatment of trigeminal neuralgia. The period from time of trigeminal nerve injury to onset of the ulcer varies from weeks to several years, with a mean of 1 to 2 years. Self-induced trauma is believed to produce the tissue destruction. Once the ulcers appear, they are extremely persistent.

Topics: Adult; Aged; Facial Dermatoses; Female; Humans; Male; Middle Aged; Nose; Skin Ulcer; Syndrome; Time Factors; Trigeminal Nerve

Topics: Acne Vulgaris; Back; Cheek; Chin; Facial Dermatoses; Forehead; Humans; Nose; Skin; Thorax

Topics: Acremonium; Ankle; Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Colony Count, Microbial; Dermatomycoses; Facial Dermatoses; Fusarium; Humans; Immunocompromised Host; Leg Dermatoses; Leukemia, Myeloid, Acute; Male; Nose; Opportunistic Infections

A 71-year-old woman suffered from pronounced erosion of her nose after soft X-ray therapy (total dose 28 Gy, half dose depth 10.5-11.5 mm). 5 weeks after the end of the irradiation no healing tendency was observed. This unusual clinical course was caused by a simultaneously existing pemphigus vulgaris that worsened after radiotherapy, presumably as a consequence of the release of epidermal antigens. In this case it is improbable that the pemphigus was induced by the radiotherapy, as has been reported on several occasions in the literature. However, this possibility cannot be entirely excluded.

Topics: Aged; Biopsy; Facial Dermatoses; Female; Humans; Keratosis; Nose; Nose Diseases; Pemphigus; Radiodermatitis; Skin; Wound Healing

Topics: Child; Facial Dermatoses; Female; Humans; Miliaria; Nose

A case of facial primary nodular cutaneous amyloidosis is reported. This illustrates: the striking appearance of this unusual condition; the investigations appropriate to establish the diagnosis and to exclude underlying systemic amyloidosis or a condition which might contribute to amyloidosis; and the difficulty of successful management. Initial investigation failed to reveal any evidence of systemic amyloidosis or an associated internal illness. Two amyloid nodules were excised, but 7 years later the patient developed further nodules on the adjacent facial skin and again sought dermatological advice. He was reinvestigated and again no underlying condition was found. A trial of cryotherapy was unsuccessful, but curettage and cautery produced a cosmetically acceptable result.

Topics: Adult; Amyloidosis; Facial Dermatoses; Humans; Male; Nose

Cutaneous sarcoidosis may occur at sites of trauma. Two patients are reported in whom lupus pernio developed in the area of facial fractures. Injury may be a factor in the site of development of lupus pernio in some individuals and may have medico-legal implications. Cutaneous sarcoidosis is known to occur at the sites of scars and trauma but lupus pernio has not been widely recognized to show this phenomenon. We report two patients in whom lupus pernio developed at the site of facial trauma.

Topics: Erythema; Facial Dermatoses; Female; Fractures, Bone; Humans; Lupus Vulgaris; Middle Aged; Nose

A 60-year-old woman with respiratory failure required ventilatory support using a continuous positive airway pressure face mask. She developed extensive necrosis of the skin of the bridge of the nose. A number of precipitating factors are discussed and suggestions made to minimise the risk of this complication.

Topics: Facial Dermatoses; Female; Humans; Lung Diseases, Obstructive; Masks; Middle Aged; Necrosis; Nose; Positive-Pressure Respiration; Pressure; Skin; Time Factors

Topics: Adult; Facial Dermatoses; Female; Humans; Nose; Syphilis, Cutaneous

Neurotrophic ulceration of the face is a rare but well recognized sequel to division of the trigeminal nerve. Trauma is an important contributory factor and thought to be due in part to paraesthesiae, which encourages picking and scratching, with resultant chronic and persistent ulceration. A case is described of an 82-year-old woman with severe trigeminal neurotrophic ulceration which improved substantially with pimozide, given for treatment of unrelated paranoid symptoms. The possible relevance of this to the established use of pimozide in delusional parasitosis is briefly discussed.

Topics: Aged; Aged, 80 and over; Atrophy; Cognition Disorders; Facial Dermatoses; Female; Humans; Nose; Pimozide; Skin Ulcer; Trigeminal Nerve

Three Japanese patients with trigeminal trophic syndrome, a rare dermatosis in Japan, were reported. Cutaneous lesions were a long-standing ulcer and destruction of the right ala nasi in case 1, a persistent deep ulceration on the forehead after a small trauma in case 2, and development of small, discrete ulcers on the right forehead during the treatment of a postherpetic neuralgia in case 3. A protective device was very effective in one patient.

Topics: Aged; Diabetes Complications; Facial Dermatoses; Female; Herpes Zoster; Humans; Male; Middle Aged; Nose; Syndrome; Trigeminal Neuralgia; Ulcer

Topics: Chromoblastomycosis; Facial Dermatoses; Humans; Male; Middle Aged; Nose

Topics: Adult; Facial Dermatoses; Humans; Keratoacanthoma; Male; Nose

The Authors report a case of Granulosis Rubra Nasi, a rare early childhood dermatitis that was also defined as "Acne papulo-rosacea of the nose". The hyperhidrosis the most conspicuous features of the disease and small beads of sweat and erythema on the tip of the nose may often occur. Sometimes small red papules and comedo-like lesions may be present.

Topics: Child; Facial Dermatoses; Humans; Hyperhidrosis; Male; Nose; Skin Diseases, Vesiculobullous

Topics: Aged; Facial Dermatoses; Female; Humans; Leishmaniasis; Nose

The report of a case of rhinozigomycosis (Rhinoentomophtoromycosis) in a forty years old male patient is presented. Full recovery was observed after one year treatment with potassium iodide (saturated solution).

Topics: Adult; Dermatomycoses; Facial Dermatoses; Humans; Male; Mucormycosis; Nose; Potassium Iodide

A form of idiopathic calcinosis cutis, subepidermal calcified nodule (SCN), recurred twice on the nasal ala of a healthy 6-year-old girl whose serum calcium and phosphorus levels were within normal limits. Basophilic granular material and numerous mast cells were present in the superficial dermis. The pathogenesis of SCN is uncertain, but the clinical and histologic features of this lesion are distinctive.

Topics: Biopsy; Calcinosis; Child; Diagnosis, Differential; Facial Dermatoses; Female; Humans; Nose; Recurrence; Staining and Labeling

Thirty-six cases of fibrous papules of the face and nose were studied by light microscopy and by immunohistochemistry. Positive staining with antibodies to vimentin and negative staining with antibodies to S-100 protein, alpha 1-antichymotrypsin, and factor VIII-RAG of the spindle, stellate, and multinucleated cells observed in the dermis support a fibroblastic line of differentiation. Fibrous papules of the nose and face are a distinctive clinicopathologic entity that most probably represents an inflammatory rather than a neoplastic process, sharing some histologic features of angiofibromas (angiofibrosis) and perifollicular fibromas (perifollicular fibrosis).

Topics: Adult; Aged; Aged, 80 and over; alpha 1-Antichymotrypsin; Antigens; Facial Dermatoses; Factor VIII; Female; Fibrosis; Humans; Immunoenzyme Techniques; Male; Middle Aged; Nose; S100 Proteins; Vimentin; von Willebrand Factor

Perioral dermatitis is an eruption that has a characteristic perioral localization. It usually responds rapidly to systemic tetracycline and low-potency topical corticosteroids. In a study of eighty-seven patients it was found that systemic erythromycin is also effective and that in some instances topical antibiotics combined with 1 per cent hydrocortisone may be effective.

Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents; Child; Chin; Erythromycin; Facial Dermatoses; Female; Humans; Hydrocortisone; Male; Nose; Tetracycline

Usually occurring on the mid-face, especially on the nose, trichostasis spinulosa occurs more commonly in young, adult black women. The lesions of trichostasis spinulosa resemble open comedones (blackheads). It may be treated with tweezing, dipilatory wax, and topical retinoic acid.

Topics: Adult; Facial Dermatoses; Female; Hair; Humans; Nose

A case of Microsporum persicolor skin infection in a casual employee of a veterinary clinic in Montreal, Quebec, Canada, is reported. A survey of 80 wild rodents in the Montreal area resulted in the isolation of M. persicolor from two voles (Clethrionomys gapperi) and one deer mouse (Peromyscus maniculatus). One of the voles, heavily infested with parasites including ticks, had obvious lesions on the nose. This is the first report of M. persicolor in rodents in North America.

Topics: Adult; Animals; Animals, Wild; Canada; Dermatomycoses; Diagnosis, Differential; Disease Reservoirs; Facial Dermatoses; Female; Humans; Microsporum; Nose; Rodentia; Skin

Topics: Aged; Arm; Cough; Drug Eruptions; Facial Dermatoses; Female; Humans; Nose; Potassium Iodide

Topics: Facial Dermatoses; Humans; Nose; Rosacea

Topics: Adult; Aged; Arm; Blister; Carcinoma, Squamous Cell; Cheek; Diagnosis, Differential; Eosinophils; Epidermal Cyst; Epithelium; Facial Dermatoses; Female; Granulation Tissue; Humans; Keratosis; Male; Middle Aged; Nose; Skin; Skin Neoplasms

Topics: Adult; Biopsy; Connective Tissue; Dilatation; Facial Dermatoses; Female; Humans; Male; Middle Aged; Mite Infestations; Nose; Rosacea; Skin; Skin Diseases; Sunburn

Topics: Adult; Aged; Carcinoma, Basal Cell; Cicatrix; Facial Dermatoses; Female; Hodgkin Disease; Humans; Keloid; Keratosis; Male; Middle Aged; Nose; Skin Diseases; Skin Neoplasms; Skin Transplantation; Surgery, Plastic; Transplantation, Autologous

Topics: Facial Dermatoses; Female; Hair; Humans; Middle Aged; Nose; Sebaceous Glands; Skin Diseases

Topics: Cheek; Eosinophilic Granuloma; Facial Dermatoses; Humans; Male; Middle Aged; Nose; Skin; Skin Transplantation; Transplantation, Autologous

Topics: Armenia; Aspergillosis; Burns; Burns, Chemical; Chemical Industry; Citrates; Facial Dermatoses; Humans; Nose; Occupational Diseases

Topics: Facial Dermatoses; Humans; Hyperhidrosis; Nose; Nose Diseases; Skin Diseases, Papulosquamous

Topics: Facial Dermatoses; Fox-Fordyce Disease; Humans; Hyperhidrosis; Nose; Nose Diseases; Skin Diseases, Papulosquamous

Topics: Facial Dermatoses; Humans; Hyperhidrosis; Intellectual Disability; Nose; Nose Diseases; Skin Diseases, Papulosquamous

Topics: Facial Dermatoses; Humans; Hyperhidrosis; Nose; Nose Diseases; Skin Diseases, Papulosquamous

Topics: Facial Dermatoses; Humans; Hyperhidrosis; Nose; Nose Diseases; Skin Diseases, Papulosquamous