phenylephrine-hydrochloride and Dermatitis

Facial dermatitis in cats can be caused by a broad range of infectious, allergic, immune-mediated and neoplastic disorders with very different treatments and prognoses. Baseline dermatologic diagnostics (skin scrapings for mites, cytology for infection and to characterize inflammatory infiltrate, and dermatophyte culture) are required, as well as possible further diagnostics, including therapeutic trials for parasites and feeding a hypoallergenic diet, bacterial culture, and skin biopsies for histopathology in order to achieve a diagnosis. Clinical presentations of diseases affecting different parts of the feline face are presented and discussed.

Topics: Animals; Cat Diseases; Cats; Dermatitis; Ear; Face; Nose

Five cases of spectacle-frame acanthoma are reported; four were retro-auricular (three unilateral; one bilateral) and one was present on the left side of the nose. Clinical aspects of the lesions are described by the light of all the other cases that have been previously reported in the literature. Histopathological features are compared to those encountered in chondrodermatitis nodularis helicis for which a frictional origin may also be suspected. In the vast majority of cases, spontaneous resolution is obtained when responsible spectacle frames are removed whereas a few lesions persist indefinitely despite of the fact that corrective measures are applied, on the contrary to what has been reported in previous papers. Apart from removing spectacles, these few cases needed surgical excision for a complete cure. Anatomo-clinical confrontations seem to indicate that those persistent lesions are completely fissured acanthomas.

Topics: Adult; Dermatitis; Diagnosis, Differential; Ear; Ear Diseases; Eyeglasses; Humans; Male; Middle Aged; Neck; Nose; Papilloma; Skin Neoplasms

Topics: Acne Vulgaris; Adult; Carcinoma, Basal Cell; Dermatitis; Diagnosis, Differential; Erythema; Exanthema; Eye Manifestations; Female; Humans; Lupus Vulgaris; Male; Middle Aged; Nose; Rosacea; Sarcoidosis; Skin Neoplasms; Telangiectasis

Chondrodermatitis nodularis helicis is an inflammatory condition affecting the helix or antihelix of the ear. It is commonly described as a solitary, painful, ulcerated nodule affecting the cartilage or skin because of continuous pressure, trauma, sun exposure, or ischemic changes. In this case report, we present a rare variant of chondrodermatitis, named chondrodermatitis nodularis nasi, which affects the skin and cartilage of the nose. Clinical resemblance to neoplasms of the skin such as squamous cell carcinoma and basal cell carcinoma requires that a biopsy be performed for definitive diagnosis. On histopathological examination, chondrodermatitis presents as a central ulcer bordered by epidermal hyperplasia, hypergranulosis, hyperkeratosis, and parakeratosis with fibrin deposits in the papillary dermis admixed with sparse inflammatory cells. Included in this case report is a discussion of the clinical and histopathology of chondrodermatitis nodularis nasi. With increased frequency of diagnosing this rare variant, better management and treatments can be explored.

Topics: Aged, 80 and over; Dermatitis; Ear Diseases; Humans; Male; Nose; Nose Diseases

A dog was referred because of the presence of painful ulcers with violaceous borders and multiple dermal and subcutaneous haemorrhagic nodules on the bridge of the nose, on the dorsal aspect of the front paws, and on all four legs. Lesions had not responded to antibacterial and immunomodulatory therapy. Nine months earlier, the dog had been diagnosed with idiopathic epilepsy and treated with potassium bromide ever since. Histopathological examination of lesions revealed an interstitial neutrophilic dermatitis multifocally extending to the subcutaneous tissue. All special stains were negative for infectious agents, and due to the lack of tropism for follicular structures as well as negative bacterial and fungal cultures, a diagnosis of a sterile neutrophilic process similar to pyoderma gangrenosum was made. A cutaneous drug reaction was suspected, potassium bromide was suspended, and after 6 weeks the ulcerative lesions were completely healed. The present report describes a case of an ulcerative neutrophilic dermatitis presumed to be associated with administration of potassium bromide that resembled human bromoderma.

Topics: Animals; Dermatitis; Dog Diseases; Dogs; Humans; Nose; Pyoderma Gangrenosum

Data regarding the treatment of periorificial dermatitis with topical calcineurin inhibitors (TCI) in the pediatric population are limited.. To assess the clinical utility of TCI in pediatric patients with periorificial dermatitis.. A retrospective medical record review of all pediatric patients with periorificial dermatitis treated with TCIs was performed. Follow-up via telephone was performed to capture missing data.. A total of 132 patients met the inclusion criteria. The median age at diagnosis was 4.2 years (interquartile range, 2.3-8.2). The median follow-up was 5.2 months (interquartile range, 2.1-11.7). Seventy-two patients had evaluable follow-up data. Of these, 48 (67%) patients were treated with TCI alone, 12 (16.7%) were treated with a combination of TCI and topical metronidazole, and 9 (12.5%) were treated with a combination of TCI and a systemic antibiotic. Complete response was noted in 68.8% of patients treated with TCI alone, in 75% of patients treated with TCI and metronidazole, and in 77.8% of patients treated with TCI and a systemic antibiotic. Adverse events were rare and mild in severity.. Topical calcineurin inhibitors are an effective therapeutic option for pediatric patients with periorificial dermatitis and were well tolerated in this cohort.

Topics: Administration, Topical; Calcineurin Inhibitors; Child; Child, Preschool; Dermatitis; Eye; Female; Humans; Male; Mouth; Nose; Retrospective Studies; Tacrolimus

Topics: Aged; Antitubercular Agents; Biopsy; Dermatitis; Ethambutol; Female; Humans; Isoniazid; Lupus Vulgaris; Mycobacterium tuberculosis; Nose; Rifampin; Treatment Outcome

This study is part of an effort to document the diversity of avian schistosomes in ducks and snails in Northern Iran, a major flyway (Black Sea/Mediterranean) for migratory birds and where cercarial dermatitis (CD) is prevalent in rice growing areas. CD is an allergic skin reaction from schistosome trematodes that emerge from aquatic snails. Most CD cases are reported from recreational swimmers or aquaculture farmers. Much of the work on the epidemiology of CD has focused in recreational waters in the Americas and Europe, with fewer studies in aquaculture, particularly in Iran. The artificial environment at aquaculture sites support dense populations of snails that are hosts to schistosomes, as well as domestic ducks. Thus, are domestic ducks reservoir hosts of species of Trichobilharzia, one of the main etiological agents of CD in Northern Iran? This study focused on a survey of domestic ducks for the presence of the nasal schistosome, T. regenti, that has been reported widely in Europe. Trichobilharzia regenti were found in domestic ducks in the Guilan Province of Iran based on morphological and molecular analyses. The presence of this species in Northern Iran indicates that the domestic duck can serve as a reservoir host for this species and that one of the local snail species is likely the intermediate host. The continued study and surveillance of this species is important because it is a neuropathic schistosome that can use a diversity of bird definitive hosts and Radix snails that are widespread across Eurasia.

Topics: Animals; Bird Diseases; Birds; Black Sea; Dermatitis; Disease Reservoirs; Ducks; Europe; Genetic Variation; Iran; Mediterranean Sea; Nose; Schistosomatidae; Schistosomiasis; Snails

In areas endemic for leishmaniosis, discoid lupus erythematosus (DLE) and canine leishmaniosis (CanL) are the most common differential diagnoses for nasal planum erosive-ulcerative dermatitis in dogs.. To compare histopathological and immunopathological features of canine nasal planum erosive-ulcerative dermatitis with depigmentation due to DLE or CanL.. Nasal planum biopsies from dogs with nasal planum loss of architecture, depigmentation, swelling, erosions or ulcerations due to DLE (n = 14) or CanL (n = 6).. Sections of paraffin-embedded samples, stained with haematoxylin and eosin were reviewed. Samples were examined using antibodies targeting T cells (CD3), B cells (CD20), macrophages (Mac387) and class II major histocompatibility complex (MHC II). Histopathological and immunophenotypical findings were compared between DLE and CanL cases.. Lichenoid and interface dermatitis were observed in both DLE and CanL cases. A nodular-to-diffuse, superficial and/or deep dermatitis with macrophages, lymphocytes and plasma cells was present only in CanL samples. CD20-positive cells predominated over CD3- and Mac387-positive cells in the two conditions. The percentage of dermal Mac387-positive cells was higher in CanL compared to DLE samples and the difference was statistically significant (P = 0.025).. In this study, similar histopathological and immunopathological findings were observed in dogs with nasal planum lesions due to DLE or CanL. Therefore, in areas endemic for leishmaniosis, the presence of the parasite should be investigated in canine nasal planum dermatitis showing clinical and histopathological features suggestive of DLE.

Topics: Animals; Dermatitis; Dog Diseases; Dogs; Female; Immunohistochemistry; Leishmaniasis; Lupus Erythematosus, Discoid; Male; Nose; Retrospective Studies

Silicone in liquid and gel implantation may induce granuloma formation and migration. Although there are many complications associated with solid silicone implantation, there have been no published reports of distant granuloma formation. We present a case of a woman with clinical and serologic findings that are consistent with systemic lupus erythematosus and a histopathologic diagnosis of foreign body granulomatous dermatitis 20 years after solid silicone nasal implantation. We review the literature on silicone granulomas and their treatment and speculate on the potential etiologies of a challenging case presentation.

Topics: Dermatitis; Female; Granuloma, Foreign-Body; Humans; Middle Aged; Nose; Prostheses and Implants; Silicone Elastomers

Topics: Amyloidosis; Dermatitis; Humans; Immunoglobulin Light Chains; Male; Middle Aged; Nose; Plasmacytoma

Topics: Dermatitis; Facial Dermatoses; Factitious Disorders; Female; Humans; Middle Aged; Nose; Skin Ulcer

Topics: Animals; Dermatitis; Diagnosis, Differential; Dog Diseases; Dogs; Female; Male; Nose; Pemphigus

Topics: Anal Canal; Animals; Balanitis; Child; Child, Preschool; Dermatitis; Female; Humans; Male; Nose; Streptococcal Infections; Streptococcus pyogenes; Vaginitis

Topics: Acne Vulgaris; Adolescent; Adult; Colony Count, Microbial; Dermatitis; Dermatitis, Atopic; Eczema; Female; Hand; Herpes Simplex; Humans; Male; Nose; Skin; Skin Diseases, Viral; Staphylococcus aureus; Tinea Pedis

Topics: Aged; Dermatitis; Female; Foreign Bodies; Humans; Nose; Sutures

Streptococcus equisimilis (Lancefield group C), an unusual cause of nosocomial surgical infection, was isolated from two orthopedic postoperative wound infections. Both operations had been performed by the same surgeon within a three-day period. Examination of the surgeon revealed perianal dermatitis from which S. equisimilis was isolated. The organism was also recovered from the surgeon's nose and rectum. The wound infections responded to treatment with penicillin derivatives. The surgeon was successfully treated with topical bacitracin and oral penicillin and vancomycin. This report documents the pathogenicity of the C Streptococcus in postoperative infection and suggests a possible nosocomial source of the organism.

Topics: Adolescent; Anal Canal; Anti-Bacterial Agents; Carrier State; Child, Preschool; Cross Infection; Dermatitis; Female; General Surgery; Humans; Medical Staff, Hospital; Nose; Rectum; Streptococcal Infections; Streptococcus; Surgical Wound Infection

Important populations of Staphylococcus aureus were found to be present on the body surfaces of live poultry originating from flocks without history of staphylococcal disease. Their sized increased considerably until approximately the seventh week of life after which time they were maintained at equally high levels. Significant correlations were found between the populations recovered from superficial wash samples and skin-tissue samples. Similarly the numbers isolated from the nasal cavities were correlated with other surface counts. Low numbers were present in the intestinal tract. Birds with staphylococcal synovitis had higher numbers in all sampling regions. The counts were very high in subjects suffering from staphylococcal dermatitis. Higher rates of positive birds and higher numbers of staphylococci were detected with a whole body sampling method than with a nasal swab technique. The isolates obtained in this study belonged to the S. aureus biotype B which is associated with poultry and pigs.

Topics: Animals; Chickens; Dermatitis; Female; Intestines; Nose; Poultry Diseases; Skin; Staphylococcal Infections; Staphylococcus; Synovitis

Topics: Candidiasis, Oral; Chordoma; Darier Disease; Dermatitis; Diagnosis, Differential; Erythema; Gingival Neoplasms; Herpes Simplex; Humans; Hypersensitivity; Nose; Palatal Neoplasms; Papilloma; Precancerous Conditions; Purpura; Skin Diseases; Skin Neoplasms; Syndrome

Topics: Animals; Dermatitis; Dog Diseases; Dogs; Female; Nose; Photosensitivity Disorders; Sunlight; Tattooing

Topics: Animals; Breeding; Congenital Abnormalities; Cryptorchidism; Deafness; Dermatitis; Dog Diseases; Dogs; Ear; Elbow; Eyelids; Hair; Hip Dislocation, Congenital; Humans; Intervertebral Disc; Male; Nose; Palate; Patella; Personality Disorders; Skin Diseases

Topics: Aged; Denervation; Dermatitis; Dysautonomia, Familial; Female; Humans; Nose; Nose Diseases; Postoperative Complications; Surgery, Plastic; Trigeminal Neuralgia

Topics: Animals; Dermatitis; Dog Diseases; Dogs; Nose; Nose Diseases; Photosensitivity Disorders; Tattooing

Topics: Child; Dermatitis; Eczema; Eosinophilia; Humans; Infant; Nose

Topics: Dermatitis; Dermoid Cyst; Humans; Nose; Nose Neoplasms

Topics: Dermatitis; Disease; Ear Diseases; Ear, External; Humans; Nose; Nose Diseases