phenylephrine-hydrochloride and Cyanosis

Topics: Body Temperature; Capillary Resistance; Cheek; Chronic Disease; Cyanosis; Diagnosis, Differential; Ear; Female; Hand; Humans; Leg; Male; Nose; Pedigree; Raynaud Disease; Sex Factors; Skin Manifestations; Temperature; Vascular Diseases

We report a case of skin necrosis of the nasal tip after an injection of ribose cross-linked porcine atelocollagen (Evolence; Colbar Life Science Ltd, Herzliya, Israel). A 22-year-old woman had a nasal augmentation. From the glabella to the nasal tip, 10 strokes were injected using 0.6 mL of Evolence. On the day of the injection, her nasal tip became cyanotic; a day after it, an erythematous condition developed and a white cheeselike material appeared. On the second day, it became necrotic. Epithelialization was completed for 2 weeks. Despite laser therapy, permanent scarring of the nasal tip was prominent at the 18-month follow-up. It was thought that the skin necrosis is caused by vascular interruption rather than by hypersensitivity because the skin necrosis was confined to the nasal tip. To avoid vascular interruption from a filler injection, aspiration is needed before injection. The least amount of filler should be released in each stroke with low-pressure injection.

Topics: Cicatrix; Collagen; Cosmetic Techniques; Cross-Linking Reagents; Cyanosis; Dermal Fillers; Erythema; Female; Follow-Up Studies; Humans; Injections; Laser Therapy; Necrosis; Nose; Re-Epithelialization; Ribose; Skin; Young Adult

We present the case of a woman where the diagnosis of cold agglutinin disease could be made after we had noticed slight cutaneous manifestations during a routine examination. Leading symptoms were livedo reticularis of the thighs and a history of acrocyanosis and Raynaud's phenomenon upon cold exposure. The current knowledge about the etiology, clinical presentation and treatment of the disease is briefly discussed.

Topics: Anemia, Hemolytic, Autoimmune; Cyanosis; Diagnosis, Differential; Ear, External; Female; Humans; Middle Aged; Nose; Raynaud Disease; Skin Diseases, Vascular; Thigh

Topics: Aged; Blood Coagulation Tests; Cyanosis; Disseminated Intravascular Coagulation; Female; Heparin; Humans; Leg Ulcer; Male; Nose; Skin Diseases; Thrombocytopenia

Two infants presented with recurrent brief cyanotic attacks and had unilateral nasal discharge. Both were poor feeders. The triad--transient cyanotic attacks, poor feeding and unilateral nasal discharge--points to unilateral upper airway obstruction. When the obstruction was relieved, the symptoms disappeared.

Topics: Airway Obstruction; Craniofacial Dysostosis; Cyanosis; Eating; Female; Humans; Infant; Infant, Newborn; Male; Nasal Mucosa; Nose; Recurrence

Topics: Cyanosis; Fetus; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Nose; Posture; Respiratory Insufficiency; Sucking Behavior

Topics: Age Factors; Cyanosis; Humans; Infant; Infant, Newborn; Infant, Premature; Nose; Reflex

Topics: Congenital Abnormalities; Cyanosis; Humans; Infant; Infant, Newborn; Nasopharynx; Nose; Surgical Procedures, Operative