phenylephrine-hydrochloride and Coccidioidomycosis

Coccidiodomycosis is a systemic infection caused by Coccidioides immitis, a dimorphic fungus endemic in the south of the USA and the north of Mexico. The disease usually affects the lungs. Primary cutaneous infection is extremely rare. We present a report of a patient with primary cutaneous infection located on the nose. To our knowledge, such a presentation has never previously been reported in the literature.. The patient had a 3-cm-diameter elevated nodule with a verrucous aspect located on the tip of her nose. The histopathologic features of the lesion were consistent with coccidioidomycosis.. To our knowledge, this is the first report of primary cutaneous coccidioidomycosis located on the tip of nose.

Topics: Adult; Antifungal Agents; Coccidioidomycosis; Facial Dermatoses; Female; Humans; Itraconazole; Nose

Topics: Biopsy; Coccidioides; Coccidioidomycosis; Female; Humans; Middle Aged; Nose; Nose Deformities, Acquired

Topics: Adult; Biopsy; Coccidioides; Coccidioidomycosis; Diagnosis, Differential; DNA, Fungal; Humans; Male; Nose

Coccidioides immitis, a pathogenic fungus endemic to arid regions, is the etiologic agent of cutaneous coccidioidomycosis. Primary cutaneous coccidioidomycosis is rare. The majority of cutaneous coccidioidomycosis infections are caused by dissemination of the fungus from the lungs to the skin. Diagnosing cutaneous coccidioidomycosis often can be difficult because it can mimic a variety of other clinical conditions. We present a case of a 45-year-old man presenting with cutaneous coccidioidomycosis on the tip of his nose. This patient had pulmonary symptoms in addition to his cutaneous findings, leading to a diagnosis of disseminated coccidioidomycosis.

Topics: Antifungal Agents; Coccidioidomycosis; Dermatomycoses; Fluconazole; Follow-Up Studies; Humans; Lung Diseases, Fungal; Male; Middle Aged; Nose; Sarcoidosis

Topics: Animals; Coccidioides; Coccidioidomycosis; Culture Media; Female; Fungal Vaccines; Genetics, Microbial; Guinea Pigs; Immunization; Injections; Injections, Subcutaneous; Liver; Lung; Male; Mice; Mutation; Nose; Spleen; Spores; Spores, Fungal; Testis; Virulence