phenylephrine-hydrochloride and Carcinoma--Mucoepidermoid

Nasopharyngeal mucoepidermoid carcinoma is a rare entity, for which surgical resection is the treatment of choice. The open technique is considered the standard approach, but this often results in significant morbidities such as trismus, dysphagia, and neurologic deficits. The advent of endoscopic endonasal techniques has made endoscopic resection a viable alternative to the open approach in terms of access, adequacy of resection, and lesser surgical morbidity. The authors describe a patient of recurrent nasopharyngeal mucoepidermoid carcinoma that was resected entirely endoscopically. The authors also present a literature review of this little-known disease and a comparison between the endoscopic and open approach.

Topics: Adult; Carcinoma, Mucoepidermoid; Female; Humans; Magnetic Resonance Imaging; Nasopharyngeal Neoplasms; Nasopharynx; Natural Orifice Endoscopic Surgery; Neoplasm Recurrence, Local; Nose

The sphenoid sinus has traditionally been considered a poorly accessible structure, situated deep in the center of the head and surrounded by vital structures. Aggressive benign and malignant tumors are usually considered to be inoperable because of the proximity of such structures, thus precluding the possibility of total extirpation. Using the transfacial-subcranial approach, lesions at this site can be totally excised. Significant tumor-free survival rates can be anticipated.

Topics: Carcinoma, Mucoepidermoid; Carcinoma, Squamous Cell; Cavernous Sinus; Craniotomy; Disease-Free Survival; Ethmoid Sinus; Head and Neck Neoplasms; Humans; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Nose; Papilloma, Inverted; Paranasal Sinus Neoplasms; Patient Care Planning; Patient Care Team; Prognosis; Sphenoid Sinus; Survival Rate