phenylephrine-hydrochloride and Astigmatism

To compare the corneal refractive changes induced after 3.0 mm temporal and nasal corneal incisions in bilateral cataract surgery.. This prospective study comprised a consecutive case series of 60 eyes from 30 patients with bilateral phacoemulsification that were implanted with a 6.0 mm foldable intraocular lens through a 3.0 mm horizontal clear corneal incision (temporal in the right eyes, nasal in the left eyes). The outcome measures were surgically induced astigmatism (SIA) and uncorrected visual acuity (UCVA) 1 and 3 months, post-operatively.. At 1 month, the mean SIA was 0.81 diopter (D) for the temporal incisions and 0.92 D for nasal incisions (P = 0.139). At 3 months, the mean SIA were 0.53 D for temporal incisions and 0.62 D for nasal incisions (P = 0.309). The UCVA was similar in the 2 incision groups before surgery, and at 1 and 3 months post-operatively.. After bilateral cataract surgery using 3.0 mm temporal and nasal horizontal corneal incisions, the induced corneal astigmatic change was similar in both incision groups. Especially in Asian eyes, both temporal and nasal incisions (3.0 mm or less) would be favorable for astigmatism-neutral cataract surgery.

Topics: Aged; Astigmatism; Cornea; Corneal Topography; Female; Follow-Up Studies; Humans; Lenses, Intraocular; Male; Minimally Invasive Surgical Procedures; Nose; Phacoemulsification; Postoperative Complications; Prospective Studies; Refraction, Ocular; Sclera; Visual Acuity

We present a family with six children of first cousin parents, in which three present with microcephaly, hypertelorism, down-slanting palpebral fissures, ptosis, a broad nasal tip, a short webbed neck, mental retardation and seizures. Two differential diagnosis, the Noonan and the Baraitser-Winter syndrome are discussed. The possibility of the description of a new MCA/MR syndrome is raised.

Topics: Abnormalities, Multiple; Astigmatism; Blepharoptosis; Brain; Child; Child, Preschool; Consanguinity; Face; Female; Genes, Recessive; Humans; Hypertelorism; Intellectual Disability; Male; Neck; Nose; Nystagmus, Pathologic; Pedigree; Seizures; Syndrome