phenylephrine-hydrochloride and Arterial-Occlusive-Diseases

An increasing number of people are undergoing non-surgical aesthetic procedures, especially injections of botulinum toxin and dermal fillers. While toxin injections have lower rates of complications, profound and serious consequences can arise with the use of dermal fillers.. A 29-year-old woman presented to the eye casualty department with sudden visual loss, ptosis and ophthalmoplegia after having had non-surgical rhinoplasty in a beauty salon in West London. The filler was administered by a healthcare professional not registered with the General Medical Council (GMC) or similar governing body.. Despite prompt measures on arrival at our service, the symptoms of visual loss, ptosis and ophthalmoplegia persisted. Attempts from the patient and medical services to report the incident (to trading standards and the police) were to no avail.. This case highlights the poor treatment response to filler-related ophthalmic complications. It is also evident that in the United Kingdom, there appears to be poor regulation in the use of these products, a lack of clear guidelines for the management of their complications and finally no recourse for patients to challenge practitioners who lack medical registration and are not held accountable.

Topics: Adult; Arterial Occlusive Diseases; Blepharoptosis; Blindness; Dermal Fillers; Female; Humans; Nose; Ophthalmic Artery; Ophthalmoplegia; Rhinoplasty; Visual Acuity

Topics: Adult; Alprostadil; Arterial Occlusive Diseases; Dermal Fillers; Female; Humans; Hyaluronic Acid; Injections, Intra-Arterial; Nose; Vasodilator Agents

Two male patients with chronic renal failure maintained on hemodialysis developed progressive clinical features of ischemic necrosis (so called calciphylaxis) of their extremities and penis. Both patients died. In one patient, penectomy provided tissue for histopathologic examination and there were changes of small artery calcification. A role of iron overload on the production of calciphylaxis is reviewed. This report is perhaps the first in nephrology literature on the occurrence of calciphylaxis involving penis and prepuce.

Topics: Aged; Arterial Occlusive Diseases; Calciphylaxis; Fatal Outcome; Foot; Gangrene; Hand; Humans; Iron; Ischemia; Kidney Failure, Chronic; Male; Necrosis; Nose; Penile Diseases; Penis; Renal Dialysis; Uremia

Visual loss occurred after subcutaneous silicone-oil injection for cosmetic purposes. To our knowledge, this is the first instance of amaurosis caused by a subcutaneous foreign-material injection that spared the central retinal artery and affected portions of the posterior ciliary-artery distribution, including a probable cilioretinal artery. The visual-field defects produced allow a rare opportunity to view the distribution of the human posterior ciliary-artery circulation by means of this in vivo pathologic embolic process. The facial arterial anatomy pertinent to ocular embolism is also discussed.

Topics: Adult; Arterial Occlusive Diseases; Blindness; Ciliary Body; Esthetics; Eye; Female; Fluorescein Angiography; Fundus Oculi; Humans; Injections, Subcutaneous; Nose; Pain; Retinal Diseases; Silicone Oils

The injection of a suspension of hydrocortisone into a keloidal scar of the nose of a 72 year-old man and of a foamy solution of hydroxypolyethoxydodecane into a little haemangioma situated above the right eyebrow of a 29 year-old woman was followed by sudden blindness of the homolateral eye in each case. This is basically explained by the involuntary injection of embolizing material into the anastomoses between the external and internal carotid arteries within the orbit. Therefore, the injection of embolizing material into the skin of the face should be avoided.

Topics: Adult; Aged; Arterial Occlusive Diseases; Blindness; Carotid Arteries; Embolization, Therapeutic; Female; Hemangioma; Humans; Keloid; Male; Nose