phenylephrine has been researched along with Insulin Resistance in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.86) | 18.7374 |
| 1990's | 12 (34.29) | 18.2507 |
| 2000's | 13 (37.14) | 29.6817 |
| 2010's | 9 (25.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cosentino, F; Costantino, S; Paneni, F | 1 |
| Liang, J; Ma, S; Pan, C; Qin, W; Ren, B; Wang, L; Wang, S; Wu, F; Zeng, B | 1 |
| Harvey, JN; Nurmikko, TJ; Schmiedel, O; Schroeter, ML; Whitaker, R | 1 |
| Li, J; Liang, Y; Niu, L; Wu, D; Xue, W; Zhang, M | 1 |
| MacLeod, KM; McNeill, JH; Nagareddy, PR | 1 |
| Bryer-Ash, M; Dorafshar, AH; Khoe, M; Lyon, C; Moodley, K | 1 |
| Beadle, RE; Eades, S; Holmes, EP; Venugopal, CS | 1 |
| Abbas, A; Beech, DJ; Channon, KM; Cubbon, RM; Gage, M; Galloway, S; Grant, PJ; Imrie, H; Kahn, M; Kearney, MT; Rajwani, A; Smith, J; Sukumar, P; Viswambharan, H; Wheatcroft, SB; Xuan, S; Yuldeshava, N | 1 |
| Galvano, F; Li Volti, G; Mangiameli, A; Salamone, F; Salomone, S; Siarkos, I; Sorrenti, V; Urso, V | 1 |
| Abdulla, MH; Abdullah, NA; Johns, EJ; Sattar, MA | 1 |
| Ali, MI; Belin de Chantemèle, EJ; Fulton, DJ; Mintz, JD; Rainey, WE; Stepp, DW; Tremblay, ML | 1 |
| Ayajiki, K; Kashiwagi, A; Nishio, Y; Okamura, T; Shinozaki, K; Sugaya, T | 1 |
| Kelly, SE; Russell, JC; Schäfer, S | 1 |
| Dreher, KL; Kelly, SE; Proctor, SD; Russell, JC | 1 |
| McNeill, JH; Nagareddy, PR; Vasudevan, H | 1 |
| Brunori, A; Burattini, R; Cogo, CE; Di Nardo, F; Ruggeri, P; Storace, D | 1 |
| Proctor, SD; Russell, JC | 1 |
| Duncan, ER; Ezzat, VA; Kearney, MT; Li, JM; Shah, AM; Walker, SJ; Wheatcroft, SB | 1 |
| Brindley, DN; Kelly, SE; Proctor, SD; Russell, JC | 1 |
| Chen, H; Guo, J; Lu, AY; Qian, FL; Sun, MW; Tao, T; Wang, J; Wang, L | 1 |
| Baue, AE; Chaudry, IH; Clemens, MG; Daigneau, N | 1 |
| Fuchs, LC; Tackett, RL; Winecoff, AP | 1 |
| Akishita, M; Han, SZ; Kim, S; Kozaki, K; Orimo, H; Ouchi, Y; Toba, K | 1 |
| Iyer, SN; Katovich, MJ | 1 |
| Davidge, ST; McKendrick, JD; O'Brien, SF; Radomski, MW; Russell, JC | 1 |
| Dubé, GP; McKendrick, JD; Murat, J; Radomski, MW; Russell, JC; Salas, E | 1 |
| Hoenig, ME; Katakam, PV; Miller, AW; Ujhelyi, MR | 1 |
| Canavan, A; Hsu, T; Miller, AW; Sims, JJ; Ujhelyi, MR | 1 |
| Davidge, ST; O'brien, SF; Russell, JC | 1 |
| Kashiwagi, A; Kikkawa, R; Nishio, Y; Okamura, T; Shinozaki, K; Toda, N | 1 |
| Ali, SS; Sowers, JR; Walsh, MF | 1 |
| Dhandayuthapani, A; Egan, BM; Gadegbeku, CA; Sadler, ZE | 1 |
| Alcántara-Hernández, R; Annabi, B; García-Sáinz, JA; Massillon, D; Robles-Flores, M; Torres-Márquez, ME; Van de Werve, G | 1 |
| Reddy, S; Sowers, JR; Zemel, MB | 1 |
| Massillon, D; van de Werve, G | 1 |
1 trial(s) available for phenylephrine and Insulin Resistance
| Article | Year |
|---|---|
Alpha adrenoceptor agonist-induced microcirculatory oscillations are reduced in diabetic neuropathy.
Topics: Adrenergic alpha-Agonists; Aged; Albuminuria; Arm; Cluster Analysis; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Female; Foot; Fourier Analysis; Glycated Hemoglobin; Humans; Hyperemia; Hypotension, Orthostatic; Insulin Resistance; Laser-Doppler Flowmetry; Logistic Models; Male; Metabolic Syndrome; Microcirculation; Middle Aged; Phenylephrine; Sensory Thresholds; Skin; Valsalva Maneuver | 2008 |
34 other study(ies) available for phenylephrine and Insulin Resistance
| Article | Year |
|---|---|
p66(Shc)-induced redox changes drive endothelial insulin resistance.
Topics: Animals; Cytochrome P-450 Enzyme System; Endothelium, Vascular; Fatty Acids, Nonesterified; Insulin; Insulin Resistance; Intramolecular Oxidoreductases; Leptin; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Obese; Molecular Targeted Therapy; NF-kappa B; Nitric Oxide Synthase Type III; Obesity; Oxidation-Reduction; Phenylephrine; Pyruvaldehyde; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Superoxides; Vasodilation | 2014 |
Apigenin and naringenin regulate glucose and lipid metabolism, and ameliorate vascular dysfunction in type 2 diabetic rats.
Topics: Animals; Anti-Inflammatory Agents; Aorta, Thoracic; Apigenin; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Fasting; Flavanones; Glucose Tolerance Test; Human Umbilical Vein Endothelial Cells; Humans; Insulin Resistance; Intercellular Adhesion Molecule-1; Lipid Metabolism; Lipid Peroxidation; Male; NF-kappa B; Nitric Oxide; Phenylephrine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Vasoconstriction; Vasodilation | 2016 |
Effects of taurine on aortic rings isolated from fructose-fed insulin resistance Sprague-Dawley rat are changed.
Topics: 4-Aminopyridine; Acetylcholine; Administration, Oral; Animals; Aorta; Blood Glucose; Blood Pressure; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Fructose; Glyburide; In Vitro Techniques; Indomethacin; Insulin; Insulin Resistance; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Peptides; Phenylephrine; Potassium Channel Blockers; Potassium Chloride; Rats; Rats, Sprague-Dawley; Taurine; Tetraethylammonium; Vasoconstriction; Vasodilation | 2008 |
GPCR agonist-induced transactivation of the EGFR upregulates MLC II expression and promotes hypertension in insulin-resistant rats.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Cardiac Myosins; Cells, Cultured; Disease Models, Animal; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Fructose; Hypertension; Insulin Resistance; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 7; Matrix Metalloproteinase Inhibitors; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Myosin Light Chains; p38 Mitogen-Activated Protein Kinases; Phenylephrine; Phosphorylation; Protease Inhibitors; Protein Kinase Inhibitors; Rats; Rats, Wistar; Receptor Cross-Talk; Receptors, Adrenergic, alpha-1; RNA Interference; Signal Transduction; Time Factors; Transfection; Up-Regulation; Vasoconstriction | 2010 |
Pioglitazone improves superoxide dismutase mediated vascular reactivity in the obese Zucker rat.
Topics: Acetylcholine; Animals; Aorta; Blood Pressure; Glucose Tolerance Test; Hypertension; Hypoglycemic Agents; Insulin Resistance; Male; Metabolic Syndrome; Nitroprusside; Obesity; Phenylephrine; Pioglitazone; Potassium Chloride; Rats; Rats, Zucker; Superoxide Dismutase; Thiazolidinediones; Vasoconstrictor Agents; Vasodilator Agents | 2010 |
Insulin resistance in equine digital vessel rings: an in vitro model to study vascular dysfunction in equine laminitis.
Topics: Androstadienes; Animals; Arteries; Foot; Foot Diseases; Forelimb; Horse Diseases; Horses; Insulin; Insulin Resistance; Phenylephrine; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Veins; Wortmannin | 2011 |
The insulin-like growth factor-1 receptor is a negative regulator of nitric oxide bioavailability and insulin sensitivity in the endothelium.
Topics: Animals; Aorta; Biological Availability; Down-Regulation; Endothelial Cells; Glucose; Glucose Intolerance; Humans; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type III; Phenylephrine; Receptor, IGF Type 1; Receptor, Insulin; Signal Transduction; Umbilical Veins; Vasoconstriction | 2011 |
Effect of silibinin on endothelial dysfunction and ADMA levels in obese diabetic mice.
Topics: Acetylcholine; Animals; Antioxidants; Aorta; Arginine; Diabetes Mellitus; Disease Models, Animal; Endothelium, Vascular; Insulin Resistance; Liver; Male; Mice; Mice, Obese; Nitroprusside; Obesity; Phenylephrine; Silybin; Silymarin; Vasoconstrictor Agents; Vasodilator Agents | 2011 |
The effect of losartan and carvedilol on renal haemodynamics and altered metabolism in fructose-fed Sprague-Dawley rats.
Topics: Angiotensin II; Animals; Body Weight; Carbazoles; Carvedilol; Fructose; Glucose Tolerance Test; Hemodynamics; Insulin Resistance; Kidney; Losartan; Male; Norepinephrine; Phenylephrine; Propanolamines; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents | 2012 |
Increasing peripheral insulin sensitivity by protein tyrosine phosphatase 1B deletion improves control of blood pressure in obesity.
Topics: Adrenergic alpha-1 Receptor Agonists; Albuminuria; Aldosterone; Animals; Blood Pressure; Dose-Response Relationship, Drug; Female; Ganglionic Blockers; Heart Rate; Hypertension; Hypertrophy; In Vitro Techniques; Insulin Resistance; Kidney Glomerulus; Male; Mecamylamine; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Knockout; Obesity; Phenylephrine; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Receptors, Leptin; Sympathetic Nervous System; Vasoconstriction | 2012 |
Evidence for a causal role of the renin-angiotensin system in vascular dysfunction associated with insulin resistance.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Blood Pressure; Calcimycin; Culture Techniques; Endothelium, Vascular; Insulin Resistance; Losartan; Male; NADPH Oxidases; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phenylephrine; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; RNA, Messenger; Superoxides; Vasoconstriction; Vasoconstrictor Agents | 2004 |
Vasopeptidase inhibition improves insulin sensitivity and endothelial function in the JCR:LA-cp rat.
Topics: Acetylcholine; Administration, Oral; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Aorta, Thoracic; Blood Glucose; Body Weight; Bradykinin; Diet; Disease Models, Animal; Eating; Endothelium, Vascular; Fasting; Heart; Heart Rate; Heterocyclic Compounds, 3-Ring; Insulin; Insulin Resistance; Male; Muscle, Smooth, Vascular; Neprilysin; NG-Nitroarginine Methyl Ester; Nitroprusside; Obesity; Organ Size; Phenylephrine; Ramipril; Rats; Vasoconstriction; Vasodilation | 2004 |
Hypersensitivity of prediabetic JCR:LA-cp rats to fine airborne combustion particle-induced direct and noradrenergic-mediated vascular contraction.
Topics: Air Pollutants; Animals; Aorta, Thoracic; Atherosclerosis; Carbon; Coal Ash; Diabetes Mellitus, Type 2; In Vitro Techniques; Insulin Resistance; Male; Particulate Matter; Phenylephrine; Rats; Rats, Inbred Strains; Vasoconstriction | 2006 |
Gonadectomy prevents endothelial dysfunction in fructose-fed male rats, a factor contributing to the development of hypertension.
Topics: Acetylcholine; Animals; Biological Factors; Blood Pressure; Body Weight; Dietary Carbohydrates; Endothelium, Vascular; Fructose; Hypertension; Insulin Resistance; Male; Nitric Oxide; Orchiectomy; Phenylephrine; Rats; Rats, Wistar; Testis; Testosterone; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2006 |
Enhanced sympathetic reactivity associates with insulin resistance in the young Zucker rat.
Topics: Adrenergic alpha-Agonists; Animals; Blood Glucose; Blood Pressure; Body Weight; Dose-Response Relationship, Drug; Glucose Tolerance Test; Heart Rate; Insulin; Insulin Resistance; Male; Obesity; Phenylephrine; Rats; Rats, Zucker; Sympathetic Nervous System; Vascular Capacitance | 2006 |
Increased insulin sensitivity and reduced micro and macro vascular disease induced by 2-deoxy-D-glucose during metabolic syndrome in obese JCR: LA-cp rats.
Topics: Acetylcholine; Adiponectin; Animals; Blood Glucose; Body Weight; Deoxyglucose; Dose-Response Relationship, Drug; Eating; Female; In Vitro Techniques; Insulin Resistance; Leptin; Male; Metabolic Syndrome; Nitroprusside; Obesity; Phenylephrine; Rats; Rats, Inbred Strains; Rats, Mutant Strains; Renal Circulation; Time Factors; Vascular Diseases; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2007 |
Accelerated endothelial dysfunction in mild prediabetic insulin resistance: the early role of reactive oxygen species.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Glucose; Blood Pressure; Endothelium, Vascular; In Vitro Techniques; Insulin; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase Type III; Nitroprusside; Phenylephrine; Prediabetic State; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Statistics, Nonparametric; Vasoconstriction | 2007 |
Pair feeding-mediated changes in metabolism: stress response and pathophysiology in insulin-resistant, atherosclerosis-prone JCR:LA-cp rats.
Topics: Animals; Aorta, Thoracic; Blood Glucose; Body Weight; Disease Models, Animal; Eating; Fatty Acids, Nonesterified; Food Deprivation; Histocytochemistry; Insulin; Insulin Resistance; Male; Metabolic Syndrome; Muscle Contraction; Myocardium; Phenylephrine; Rats; Restraint, Physical; Stress, Physiological; Triglycerides; Vasoconstrictor Agents | 2008 |
Low-intensity voluntary running lowers blood pressure with simultaneous improvement in endothelium-dependent vasodilatation and insulin sensitivity in aged spontaneously hypertensive rats.
Topics: Acetylcholine; Aging; Animals; Aorta, Thoracic; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Hypertension; Insulin Resistance; Male; Nitroprusside; Phenylephrine; Physical Conditioning, Animal; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2008 |
Insulin resistance and depressed gluconeogenic capability during early hyperglycemic sepsis.
Topics: Abdomen; Animals; Dose-Response Relationship, Drug; Gluconeogenesis; Infections; Insulin; Insulin Resistance; Liver; Phenylephrine; Rats | 1984 |
Insulin attenuates alpha-adrenergic aortic contraction in normotensive but not borderline hypertensive rats.
Topics: Animals; Aorta, Thoracic; Female; Hypertension; In Vitro Techniques; Insulin; Insulin Resistance; Male; Norepinephrine; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Vasoconstriction | 1995 |
Augmented contractile function and abnormal Ca2+ handling in the aorta of Zucker obese rats with insulin resistance.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Agonists; Animals; Aorta; Calcium; Calcium Channel Agonists; Calcium Channels; Hyperinsulinism; In Vitro Techniques; Insulin Resistance; Ion Channel Gating; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Obesity; Phenylephrine; Potassium Chloride; Rats; Rats, Wistar; Rats, Zucker; Vasodilation | 1996 |
Vascular reactivity to phenylephrine and angiotensin II in hypertensive rats associated with insulin resistance.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Fructose; Hypertension; Insulin Resistance; Male; Phenylephrine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Vasoconstriction | 1996 |
Vascular wall reactivity in conductance and resistance arteries: differential effects of insulin resistance.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Endothelium, Vascular; In Vitro Techniques; Insulin Resistance; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Norepinephrine; Obesity; Phenylephrine; Rats; Rats, Mutant Strains; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents | 1998 |
Inhibition of nitric oxide generation unmasks vascular dysfunction in insulin-resistant, obese JCR:LA-cp rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Platelets; Blood Pressure; Cyclic GMP; Diabetes Mellitus; Enzyme Inhibitors; Genotype; Insulin Resistance; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Obesity; Penicillamine; Phenylephrine; Rats; S-Nitroso-N-Acetylpenicillamine; Vasoconstrictor Agents; Vasodilator Agents | 1998 |
Endothelial dysfunction precedes hypertension in diet-induced insulin resistance.
Topics: Animals; Dietary Carbohydrates; Endothelium, Vascular; Fructose; Hypertension; Insulin Resistance; Male; Mesenteric Arteries; Phenylephrine; Rats; Rats, Sprague-Dawley; Time Factors; Vasoconstriction; Vasoconstrictor Agents | 1998 |
Impaired vagal reflex activity in insulin-resistant rats.
Topics: Animals; Baroreflex; Blood Pressure; Heart Rate; Hyperinsulinism; Insulin Resistance; Male; Nitroprusside; Phenylephrine; Random Allocation; Rats; Rats, Sprague-Dawley; Vagus Nerve; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
Vascular wall dysfunction in JCR:LA-cp rats: effects of age and insulin resistance.
Topics: Acetylcholine; Aging; Animals; Arteriosclerosis; Blood Glucose; Body Weight; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Eicosanoids; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Insulin; Insulin Resistance; Male; Meclofenamic Acid; Mesenteric Arteries; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Norepinephrine; Obesity; Phenylephrine; Rats; Rats, Mutant Strains; Triglycerides; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
Free radical production in endothelial cells as a pathogenetic factor for vascular dysfunction in the insulin resistance state.
Topics: Acetylcholine; Animals; Calcimycin; Endothelium, Vascular; Free Radicals; Fructose; Hyperinsulinism; In Vitro Techniques; Indomethacin; Insulin; Insulin Resistance; Luminescent Measurements; Male; Models, Cardiovascular; Muscle, Smooth, Vascular; Nitric Oxide; Phenylephrine; Rats; Rats, Sprague-Dawley; Superoxides; Vasodilation | 1999 |
Vascular insulin/insulin-like growth factor-1 resistance in female obese Zucker rats.
Topics: Animals; Aorta; Cholera Toxin; Deoxyglucose; Drug Resistance; Endothelium, Vascular; Female; GTP-Binding Proteins; Insulin Resistance; Insulin-Like Growth Factor I; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Obesity; Pertussis Toxin; Phenylephrine; Protein-Tyrosine Kinases; Rats; Rats, Zucker; Receptor, Insulin; Tritium; Virulence Factors, Bordetella | 2001 |
Raising lipids acutely reduces baroreflex sensitivity.
Topics: Adrenergic alpha-Agonists; Adult; Baroreflex; Blood Pressure; Fat Emulsions, Intravenous; Fatty Acids, Nonesterified; Female; Heparin; Humans; Hyperlipidemias; Hypertension; Insulin Resistance; Male; Obesity; Phenylephrine | 2002 |
Modulation by protein kinase C of the hormonal responsiveness of hepatocytes from lean (Fa/fa?) and obese (fa/fa) Zucker rats.
Topics: Animals; Enzyme Activation; Insulin Resistance; Isoenzymes; Isoproterenol; Liver; Obesity; Phenylephrine; Phorbol Esters; Phosphorylation; Protein Kinase C; Rats; Rats, Zucker | 1992 |
Insulin attenuation of vasoconstrictor responses to phenylephrine in Zucker lean and obese rats.
Topics: Animals; Hypertension; Insulin; Insulin Resistance; Male; Obesity; Phenylephrine; Rats; Rats, Zucker; Vasoconstriction | 1991 |
Altered regulation of glycogen metabolism by vasopressin and phenylephrine in hepatocytes from insulin-resistant obese (fa/fa) rats. Role of protein kinase C.
Topics: Animals; Enzyme Activation; Female; Glycogen Synthase; Insulin Resistance; Liver Glycogen; Obesity; Phenylephrine; Phorbol Esters; Phosphorylases; Protein Kinase C; Rats; Stimulation, Chemical; Type C Phospholipases; Vasopressins | 1990 |