Page last updated: 2024-08-16

phenylephrine and Hypertrophy, Left Ventricular

phenylephrine has been researched along with Hypertrophy, Left Ventricular in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (23.81)18.2507
2000's5 (23.81)29.6817
2010's8 (38.10)24.3611
2020's3 (14.29)2.80

Authors

AuthorsStudies
Chen, Y; Cui, J; Cui, Y; Li, M; Tang, X; Wang, P; Wang, Y; Zhang, T1
Alderdice, M; Amirkhah, R; Dunne, PD; Edgar, KS; Grieve, DJ; Harvey, AP; McDermott, BJ; McMullan, R; O'Neill, KM; Robinson, E1
Chen, H; Guo, W; Hu, P; Lu, R; Shan, X; Tian, J; Wang, S; Wu, Q; Xu, M; Zhang, C; Zhao, P; Zheng, J1
Ciccarelli, M; Iaccarino, G; Illario, M; Maione, AS; Santulli, G; Sorriento, D; Trimarco, B1
Chang, YT; Chang, YW; Chen, CC; Chen, YJ; Lin, JJ; Wang, Q1
Abdulla, MH; Abdullah, NA; Ahmad, A; Johns, EJ; Kaur, G; Khan, SA; Rathore, HA; Sattar, MA1
Campiglia, P; Ciccarelli, M; Cipolletta, E; Franco, A; Gambardella, J; Gomez-Monterrey, I; Iaccarino, G; Napolitano, L; Santulli, G; Sorriento, D; Trimarco, B1
Bin, J; Chen, Z; Hao, H; Huang, X; Kitakaze, M; Li, Q; Li, X; Liao, W; Liao, Y; Lin, H; Xie, J; Xuan, W1
Bache, RJ; Bernlohr, DA; Chen, Y; Fassett, J; Hu, X; Viollet, B; Wiczer, B; Xu, W; Xu, X; Zhang, P; Zhu, G1
Ackerman, A; Aronovitz, MJ; Baker, C; Donaldson, C; Eder, S; Hall-Porter, M; Karas, RH; Molkentin, JD; Patten, RD; Wang, F; Weiss, AD1
Kassan, M; Montero, MJ; Sevilla, MA1
Backx, P; Clement, S; Dziak, E; Kabir, G; Opas, M; Papp, S1
Backx, PH; Bolz, SS; Farman, GP; Kirshenbaum, LA; Latour-Villamil, D; Panama, BK; Zhao, D1
Carrier, L; Eschenhagen, T; Geertz, B; Mearini, G; Schlossarek, S; Schuermann, F1
Bicknell, KA; Brooks, G; Coxon, CH; Vara, D1
Cheinberg, BV; Kedem, J; Roitstein, A; Scholz, PM; Tse, J; Weiss, HR1
Xu, DL1
Akhter, SA; Iaccarino, G; Koch, WJ; Lefkowitz, RJ; Luttrell, LM; Rockman, HA1
Blumer, KJ; Courtois, M; Kelly, DP; Kovacs, A; Muslin, AJ; Rogers, JH; Tamirisa, P; Weinheimer, C1
Davey, P1
Ayers, GM; Ben-David, J; Pride, HP; Zipes, DP1

Other Studies

21 other study(ies) available for phenylephrine and Hypertrophy, Left Ventricular

ArticleYear
Cinnamic acid mitigates left ventricular hypertrophy and heart failure in part through modulating FTO-dependent N
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 165

    Topics: Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Disease Models, Animal; Heart Failure; Hypertrophy, Left Ventricular; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Phenylephrine; RNA

2023
Downregulation of PPARα during Experimental Left Ventricular Hypertrophy Is Critically Dependent on Nox2 NADPH Oxidase Signalling.
    International journal of molecular sciences, 2020, Jun-20, Volume: 21, Issue:12

    Topics: Animals; Cell Line; Disease Models, Animal; Gene Expression Regulation; Hypertrophy, Left Ventricular; Male; Mice; Myocytes, Cardiac; NADPH Oxidase 2; Oxidative Stress; Phenylephrine; PPAR alpha; Rats; Signal Transduction

2020
Stachydrine hydrochloride suppresses phenylephrine-induced pathological cardiac hypertrophy by inhibiting the calcineurin/nuclear factor of activated T-cell signalling pathway.
    European journal of pharmacology, 2020, Sep-15, Volume: 883

    Topics: Animals; Calcineurin; Cells, Cultured; Disease Models, Animal; Gene Expression Regulation; Hypertrophy, Left Ventricular; Mice, Inbred C57BL; Myocytes, Cardiac; NFATC Transcription Factors; Phenylephrine; Proline; Rats, Wistar; Signal Transduction; Ventricular Function, Left; Ventricular Remodeling

2020
The Amino-Terminal Domain of GRK5 Inhibits Cardiac Hypertrophy through the Regulation of Calcium-Calmodulin Dependent Transcription Factors.
    International journal of molecular sciences, 2018, Mar-15, Volume: 19, Issue:3

    Topics: Animals; Binding Sites; Calmodulin; Cell Line; G-Protein-Coupled Receptor Kinase 5; GATA4 Transcription Factor; Hypertrophy, Left Ventricular; Male; Myocytes, Cardiac; NFATC Transcription Factors; Phenylephrine; Protein Binding; Rats; Rats, Inbred SHR; Rats, Wistar

2018
Quantitative phosphoproteomic study of pressure-overloaded mouse heart reveals dynamin-related protein 1 as a modulator of cardiac hypertrophy.
    Molecular & cellular proteomics : MCP, 2013, Volume: 12, Issue:11

    Topics: Animals; Cardiomegaly; Cells, Cultured; Dynamins; Hypertrophy, Left Ventricular; Male; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Oxygen Consumption; Phenylephrine; Phosphorylation; Proteomics; Rats; Signal Transduction

2013
Functional contribution of α1D-adrenoceptors in the renal vasculature of left ventricular hypertrophy induced with isoprenaline and caffeine in Wistar-Kyoto rats.
    Canadian journal of physiology and pharmacology, 2014, Volume: 92, Issue:12

    Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Arterial Pressure; Caffeine; Hemodynamics; Hypertrophy, Left Ventricular; Isoproterenol; Kidney; Male; Methoxamine; Norepinephrine; Phenylephrine; Piperazines; Rats, Inbred WKY; Receptors, Adrenergic, alpha-1; Regional Blood Flow; Vasoconstrictor Agents

2014
Integrating GRK2 and NFkappaB in the Pathophysiology of Cardiac Hypertrophy.
    Journal of cardiovascular translational research, 2015, Volume: 8, Issue:8

    Topics: Animals; Atrial Natriuretic Factor; Cell Line; Disease Models, Animal; G-Protein-Coupled Receptor Kinase 2; Gene Knockdown Techniques; Hypertrophy, Left Ventricular; Male; Mice, Knockout; Mutation; Myocytes, Cardiac; NF-kappa B; Phenylephrine; Phosphorylation; Protein Kinase Inhibitors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; Transduction, Genetic; Transfection

2015
FGF23 promotes myocardial fibrosis in mice through activation of β-catenin.
    Oncotarget, 2016, Oct-04, Volume: 7, Issue:40

    Topics: Angiotensin II; Animals; beta Catenin; Cells, Cultured; Collagen; Dependovirus; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibroblasts; Fibrosis; Humans; Hypertrophy, Left Ventricular; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardium; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptor, Fibroblast Growth Factor, Type 4; Reperfusion Injury; RNA, Small Interfering; Transforming Growth Factor beta; Up-Regulation

2016
AMP activated protein kinase-alpha2 deficiency exacerbates pressure-overload-induced left ventricular hypertrophy and dysfunction in mice.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 52, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; AMP-Activated Protein Kinases; Animals; Carrier Proteins; Cell Cycle Proteins; Cells, Cultured; DNA-Binding Proteins; Eukaryotic Initiation Factors; Hypertension; Hypertrophy, Left Ventricular; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Multienzyme Complexes; Myocytes, Cardiac; Phenylephrine; Phosphoproteins; Protein Serine-Threonine Kinases; Ribosomal Protein S6; Ribosomal Protein S6 Kinases, 70-kDa; Stroke Volume; Transcription Factors; Ventricular Dysfunction, Left

2008
Estrogen attenuates left ventricular and cardiomyocyte hypertrophy by an estrogen receptor-dependent pathway that increases calcineurin degradation.
    Circulation research, 2009, Jan-30, Volume: 104, Issue:2

    Topics: Animals; Animals, Newborn; Calcineurin; Cell Size; Cells, Cultured; Disease Models, Animal; Drug Implants; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Hemodynamics; Hypertrophy, Left Ventricular; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Myocardial Contraction; Myocardium; Myocytes, Cardiac; NFATC Transcription Factors; Ovariectomy; Phenylephrine; Proteasome Endopeptidase Complex; Receptors, Estrogen; Signal Transduction; Time Factors; Ubiquitin; Ventricular Function, Left; Ventricular Remodeling

2009
Chronic treatment with pravastatin prevents early cardiovascular changes in spontaneously hypertensive rats.
    British journal of pharmacology, 2009, Volume: 158, Issue:2

    Topics: Animals; Blood Pressure; Cardiovascular Diseases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Hypertrophy, Left Ventricular; Lipid Peroxidation; Male; Nitric Oxide; Nitroprusside; Oxidative Stress; Phenylephrine; Pravastatin; Rats; Rats, Inbred SHR; Superoxides

2009
Evidence for calreticulin attenuation of cardiac hypertrophy induced by pressure overload and soluble agonists.
    The American journal of pathology, 2010, Volume: 176, Issue:3

    Topics: Animals; Aorta; Calreticulin; Cardiomegaly; Constriction, Pathologic; Embryo, Mammalian; Endothelin-1; Gene Expression Regulation; Heart Ventricles; Hemodynamics; Hypertrophy, Left Ventricular; Male; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Organ Size; Phenylephrine; Pressure; Signal Transduction; Solubility; src-Family Kinases

2010
Nuclear factor kappaB downregulates the transient outward potassium current I(to,f) through control of KChIP2 expression.
    Circulation research, 2011, Mar-04, Volume: 108, Issue:5

    Topics: Animals; Cells, Cultured; Disease Models, Animal; Down-Regulation; Hypertrophy, Left Ventricular; Kv Channel-Interacting Proteins; Myocytes, Cardiac; NF-kappa B; Phenylephrine; Potassium Channels; Propranolol; Rats; Rats, Sprague-Dawley; Shal Potassium Channels; Tumor Necrosis Factor-alpha

2011
Adrenergic stress reveals septal hypertrophy and proteasome impairment in heterozygous Mybpc3-targeted knock-in mice.
    Journal of muscle research and cell motility, 2012, Volume: 33, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Alleles; Animals; Cardiomyopathy, Hypertrophic; Carrier Proteins; Cytosol; Echocardiography; Gene Knock-In Techniques; Gene Transfer Techniques; Heterozygote; Homologous Recombination; Humans; Hypertrophy, Left Ventricular; Isoproterenol; Mice; Mice, Transgenic; Mutation; Phenotype; Phenylephrine; Proteasome Endopeptidase Complex; Sodium Chloride; Stress, Physiological

2012
Inhibition of E2F abrogates the development of cardiac myocyte hypertrophy.
    The Journal of biological chemistry, 2003, Jun-13, Volume: 278, Issue:24

    Topics: 3T3 Cells; Animals; Cell Cycle Proteins; Cyclin E; Dimerization; DNA-Binding Proteins; Down-Regulation; E2F Transcription Factors; E2F1 Transcription Factor; E2F5 Transcription Factor; Female; Flow Cytometry; G1 Phase; Hypertrophy; Hypertrophy, Left Ventricular; Immunoblotting; Luciferases; Mice; Myocardium; Peptides; Phenylephrine; Polymerase Chain Reaction; Promoter Regions, Genetic; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA; S Phase; Time Factors; Transcription Factors; Up-Regulation

2003
Reduced effect of phenylephrine on regional myocardial function and O2 consumption in experimental LVH.
    The American journal of physiology, 1995, Volume: 268, Issue:3 Pt 2

    Topics: Animals; Coronary Circulation; Disease Models, Animal; Dogs; Hypertrophy, Left Ventricular; Myocardial Contraction; Myocardium; Oxygen Consumption; Phenylephrine; Receptors, Adrenergic, alpha-1; Regional Blood Flow; Second Messenger Systems

1995
[Ras oncogene expression of left ventricle in hypertrophic rat heart and during induction by vasopressin and neosynephrine].
    Zhonghua xin xue guan bing za zhi, 1993, Volume: 21, Issue:3

    Topics: Animals; Gene Expression; Genes, myc; Genes, ras; Hypertrophy, Left Ventricular; Male; Phenylephrine; Rats; Rats, Wistar; RNA, Messenger; Vasopressins

1993
Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy.
    Science (New York, N.Y.), 1998, Apr-24, Volume: 280, Issue:5363

    Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; COS Cells; Diglycerides; Enzyme Activation; Gene Expression Regulation; Gene Targeting; GTP-Binding Proteins; Hypertrophy, Left Ventricular; Inositol Phosphates; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinase 1; Myocardium; Peptide Fragments; Phenylephrine; Receptors, Adrenergic, alpha; Signal Transduction; Transfection; Transgenes; Ventricular Pressure

1998
RGS4 causes increased mortality and reduced cardiac hypertrophy in response to pressure overload.
    The Journal of clinical investigation, 1999, Volume: 104, Issue:5

    Topics: Adaptation, Physiological; Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Constriction; Gene Expression Regulation; GTPase-Activating Proteins; Heart Rate; Hypertrophy, Left Ventricular; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardial Contraction; Myocardium; Myosin Heavy Chains; Phenylephrine; Pressure; Promoter Regions, Genetic; Proteins; Signal Transduction; Ventricular Dysfunction, Left

1999
QT interval lengthening in cardiac disease relates more to left ventricular systolic dysfunction than to autonomic function.
    European journal of heart failure, 2000, Volume: 2, Issue:3

    Topics: Autonomic Nervous System; Baroreflex; Biomarkers; Echocardiography; Electrocardiography; Epinephrine; Heart Conduction System; Heart Failure; Heart Rate; Humans; Hypertrophy, Left Ventricular; Middle Aged; Myocardial Contraction; Norepinephrine; Phenylephrine; Sympathomimetics; Vagus Nerve; Ventricular Dysfunction, Left

2000
Canine left ventricular hypertrophy predisposes to ventricular tachycardia induction by phase 2 early afterdepolarizations after administration of BAY K 8644.
    Journal of the American College of Cardiology, 1992, Volume: 20, Issue:7

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Causality; Cesium; Death, Sudden, Cardiac; Disease Models, Animal; Dogs; Evaluation Studies as Topic; Hemodynamics; Hypertrophy, Left Ventricular; Incidence; Organ Size; Phenylephrine; Prevalence; Tachycardia, Ventricular; Time Factors

1992