Page last updated: 2024-08-16

phenylephrine and Hypertension, Pulmonary

phenylephrine has been researched along with Hypertension, Pulmonary in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19904 (11.43)18.7374
1990's9 (25.71)18.2507
2000's10 (28.57)29.6817
2010's11 (31.43)24.3611
2020's1 (2.86)2.80

Authors

AuthorsStudies
Chen, J; Chen, Y; Li, X; Li, Y; Liao, J; Lin, Z; Liu, S; Luo, X; Miao, J; Parmisano, S; Sun, D; Wang, J; Wang, Z; Xing, Y; Yang, K; Yuan, JX; Zhang, C; Zhang, Z; Zhao, M; Zhou, D1
Breuer, J; Knies, R; Lorenz, K; Matthey, M; Neumann, V; Seidinger, A; Simon, A; Wenzel, D1
Goto, T; Mizuno, Y; Oku, S; Sugawara, Y1
Feinstein, JA; Ogawa, MT; Peng, LF; Ramamoorthy, C; Siehr, SL; Yang, W1
Gui, LX; Jiao, HX; Lin, DC; Lin, MJ; Mu, YP; Yan, FR1
Gurney, AM; Howarth, FC1
Dong, MQ; Gao, YQ; Li, ZC; Liu, LL; Liu, ML; Luo, Y; Wang, J; Xu, DQ; Xu, M; Zhang, B; Zhao, PT1
Chai, TS; Charchaflieh, J; Svyatets, M1
Billaud, M; Dahan, D; Guibert, C; Marthan, R; Savineau, JP1
Arons, E; Christou, H; Khalil, RA; Kourembanas, S; Mam, V; Mitsialis, SA; Reslan, OM; Tanbe, AF; Touma, M; Vitali, SH1
Coves, S; Holgado, CM1
Cao, W; Chen, WS; Dong, L; Li, XQ; Xiao, X; Zhang, JZ1
Barreiro, EJ; do Nascimento, JH; Ferraz, EB; Fraga, CA; Kummerle, AE; Pereira, SL; Rocha, Nde N; Sudo, RT; Zapata-Sudo, G1
Berends, N; Leather, HA; Segers, P; Vandermeersch, E; Wouters, PF1
Armentano, RL; Bia, D; Ginés, FF; Grignola, JC1
BECK, W; SCHRIRE, V; VOGELPOEL, L1
Bonnet, S; Marthan, R; Pauvert, O; Rousseau, E; Savineau, JP1
Armentano, RL; Barra, JG; Ginés, FF; Grignola, JC; Santana, DB1
Brown, JW; Fiore, AC; Meldrum, DR; Sheridan, BC; Tsai, BM; Turrentine, MW; Wang, M1
Aigrain, Y; Barbet, JP; de Buys Roessingh, AS; de Lagausie, P; Dinh-Xuan, AT; Mercier, JC1
Bartel, S; Morwinski, R; Okruhlicova, L; Schulze, W; Tribulova, N; Wallukat, G; Weismann, P1
Ballard, HJ; Balonan, L; Das, R; Ho, S1
Brown, D; Carrithers, JA; Liu, F; Orr, JA1
Abman, SH; Ivy, DD; Kinsella, JP; McMurtry, IF; McQueston, JA1
Gomez, A; Mink, SN; Unruh, H1
Dignan, RJ; Kadletz, M; Wechsler, AS1
Beck, GR; Hay, DW; Luttmann, MA; Mitchell, MP; Ohlstein, EH; Sauermelch, CF; Willette, RN1
Itoh, A; Kondo, M; Matsukura, Y; Motoyoshi, S; Nakajyo, S; Shimizu, K; Urakawa, N; Washizu, M1
Abdel-Razek, TT; Abrams, GA; Chen, SJ; Chen, YF; Dai, J; Fallon, MB; Ku, DD; Luo, B; Oparil, S1
Hong, YW; Kwak, YL; Lee, CS; Park, YH1
Hoffman, JI; Turley, K; Vlahakes, GJ1
Turley, K1
Gubin, S; Hart, K; Rich, S1
Follath, F1
Meadow, WL; Rudinsky, BF; Strates, E1

Trials

2 trial(s) available for phenylephrine and Hypertension, Pulmonary

ArticleYear
Hemodynamic Effects of Phenylephrine, Vasopressin, and Epinephrine in Children With Pulmonary Hypertension: A Pilot Study.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2016, Volume: 17, Issue:5

    Topics: Adolescent; Arginine Vasopressin; Child; Child, Preschool; Epinephrine; Female; Humans; Hypertension, Pulmonary; Infant; Male; Phenylephrine; Pilot Projects; Prospective Studies; Treatment Outcome; Vascular Resistance; Vasoconstrictor Agents

2016
The effect of phenylephrine and norepinephrine in patients with chronic pulmonary hypertension*.
    Anaesthesia, 2002, Volume: 57, Issue:1

    Topics: Adult; Chronic Disease; Female; Heart Septal Defects; Heart Valve Prosthesis Implantation; Hemodynamics; Humans; Hypertension, Pulmonary; Hypotension; Intraoperative Complications; Male; Middle Aged; Norepinephrine; Phenylephrine; Vasoconstrictor Agents

2002

Other Studies

33 other study(ies) available for phenylephrine and Hypertension, Pulmonary

ArticleYear
Upregulation of mechanosensitive channel Piezo1 involved in high shear stress-induced pulmonary hypertension.
    Thrombosis research, 2022, Volume: 218

    Topics: Acetylcholine; Animals; Cell Proliferation; Hypertension, Pulmonary; Membrane Proteins; Muscle, Smooth, Vascular; Phenylephrine; Pulmonary Artery; Rats; Transcription Factor 4; Up-Regulation; Vascular Remodeling; YAP-Signaling Proteins

2022
The β
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2018, Volume: 32, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic beta-2 Receptor Agonists; Animals; Blood Pressure; Hypertension, Pulmonary; Hypoxia; Lung; Mice; Phenylephrine; Pulmonary Artery; Receptors, Adrenergic, alpha-1; Terbutaline

2018
Effects of vasopressin during a pulmonary hypertensive crisis induced by acute hypoxia in a rat model of pulmonary hypertension.
    British journal of anaesthesia, 2019, Volume: 122, Issue:4

    Topics: Acute Disease; Animals; Drug Evaluation, Preclinical; Echocardiography; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Male; Monocrotaline; Nordefrin; Oxygen; Partial Pressure; Phenylephrine; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents; Vasopressins

2019
Alterations in Caveolin-1 Expression and Receptor-Operated Ca2+ Entry in the Aortas of Rats with Pulmonary Hypertension.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016, Volume: 39, Issue:2

    Topics: Animals; Aorta; Blotting, Western; Calcium; Caveolae; Caveolin 1; Cells, Cultured; Gene Expression; Hypertension, Pulmonary; Male; Microscopy, Electron, Transmission; Myocytes, Smooth Muscle; Phenylephrine; Rats, Sprague-Dawley; Receptors, Cell Surface; Reverse Transcriptase Polymerase Chain Reaction; TRPC Cation Channels; Vasoconstriction; Vasoconstrictor Agents

2016
Effects of streptozotocin-induced diabetes on the pharmacology of rat conduit and resistance intrapulmonary arteries.
    Cardiovascular diabetology, 2009, Jan-21, Volume: 8

    Topics: Animals; Calcium Signaling; Carbachol; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Dinoprost; Endothelium, Vascular; Hypertension, Pulmonary; Male; Membrane Potentials; Muscle, Smooth, Vascular; Nitroglycerin; Phenylephrine; Potassium; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Wistar; Serotonin; Streptozocin; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents

2009
Tanshinone IIA modulates pulmonary vascular response to agonist and hypoxia primarily via inhibiting Ca2+ influx and release in normal and hypoxic pulmonary hypertension rats.
    European journal of pharmacology, 2010, Aug-25, Volume: 640, Issue:1-3

    Topics: Abietanes; Animals; Calcium; Carbon Monoxide; Endothelium, Vascular; Extracellular Space; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Intracellular Space; Male; Nitric Oxide; Phenanthrenes; Phenylephrine; Potassium; Potassium Channel Blockers; Prostaglandins; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vasoconstriction

2010
Pulmonary hypertension in a patient with subarachnoid hemorrhage.
    Journal of neurosurgical anesthesiology, 2011, Volume: 23, Issue:3

    Topics: Cardiotonic Agents; Coronary Angiography; Echocardiography; Embolization, Therapeutic; Humans; Hypertension, Pulmonary; Male; Middle Aged; Milrinone; Phenylephrine; Subarachnoid Hemorrhage; Treatment Outcome

2011
Role of the gap junctions in the contractile response to agonists in pulmonary artery from two rat models of pulmonary hypertension.
    Respiratory research, 2011, Mar-17, Volume: 12

    Topics: Analysis of Variance; Animals; Blood Pressure; Blotting, Western; Connexin 43; Connexins; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin-1; Fluorescent Antibody Technique; Gap Junction alpha-4 Protein; Gap Junction alpha-5 Protein; Gap Junctions; Hypertension, Pulmonary; Hypoxia; Male; Monocrotaline; Muscle, Smooth, Vascular; Phenylephrine; Pulmonary Artery; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Serotonin; Vasoconstriction; Vasoconstrictor Agents

2011
Improved pulmonary vascular reactivity and decreased hypertrophic remodeling during nonhypercapnic acidosis in experimental pulmonary hypertension.
    American journal of physiology. Lung cellular and molecular physiology, 2012, May-01, Volume: 302, Issue:9

    Topics: Acetylcholine; Acidosis, Respiratory; Airway Remodeling; Ammonium Chloride; Animals; Antihypertensive Agents; Blood Pressure; Carbon Dioxide; Cholinergic Agonists; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy; Hypoxia; In Vitro Techniques; Lung; Male; Monocrotaline; Nitroprusside; Organ Size; Phenylephrine; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Signal Transduction; Vasoconstriction; Vasoconstrictor Agents

2012
[Anaesthetic management of caesarean section in pregnancy with diabetes and hypertrophic myocardiopathy with restrictive diastolic dysfunction].
    Revista espanola de anestesiologia y reanimacion, 2013, Volume: 60, Issue:2

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Betamethasone; Cardiomyopathy, Hypertrophic; Cardiovascular Agents; Cesarean Section, Repeat; Diabetes Mellitus, Type 1; Diastole; Female; Heart Failure; Humans; Hypertension, Pulmonary; Hypotension; Infant, Newborn; Intraoperative Complications; Norepinephrine; Oxytocin; Phenylephrine; Pre-Eclampsia; Preanesthetic Medication; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy in Diabetics; Supine Position

2013
Vardenafil ameliorates calcium mobilization in pulmonary artery smooth muscle cells from hypoxic pulmonary hypertensive mice.
    Archives of medical research, 2012, Volume: 43, Issue:4

    Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Chronic Disease; Drug Evaluation, Preclinical; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Imidazoles; Inositol 1,4,5-Trisphosphate Receptors; Ion Transport; Male; Mice; Mice, Inbred C57BL; Myocytes, Smooth Muscle; Patch-Clamp Techniques; Phenylephrine; Piperazines; Potassium; Sarcoplasmic Reticulum; Sulfones; Triazines; Vardenafil Dihydrochloride; Vasodilation; Vasodilator Agents

2012
A novel Ca2+ channel antagonist reverses cardiac hypertrophy and pulmonary arteriolar remodeling in experimental pulmonary hypertension.
    European journal of pharmacology, 2013, Feb-28, Volume: 702, Issue:1-3

    Topics: Acetylcholine; Animals; Benzodioxoles; Calcium Channel Blockers; Calcium Chloride; Cardiomegaly; Familial Primary Pulmonary Hypertension; Hydrazones; Hypertension, Pulmonary; In Vitro Techniques; Male; Monocrotaline; Phenylephrine; Pulmonary Artery; Rats; Rats, Wistar; Vasoconstrictor Agents; Vasodilator Agents

2013
Effects of vasopressin on right ventricular function in an experimental model of acute pulmonary hypertension.
    Critical care medicine, 2002, Volume: 30, Issue:11

    Topics: Acute Disease; Analysis of Variance; Animals; Arginine Vasopressin; Dogs; Hemodynamics; Hypertension, Pulmonary; Phenylephrine; Prospective Studies; Stroke Volume; Vascular Resistance; Vasoconstrictor Agents; Ventricular Dysfunction, Right

2002
Improved pulmonary artery buffering function during phenylephrine-induced pulmonary hypertension.
    Molecular and cellular biochemistry, 2003, Volume: 246, Issue:1-2

    Topics: Animals; Blood Pressure; Elasticity; Hypertension, Pulmonary; Muscle, Smooth, Vascular; Phenylephrine; Pulmonary Artery; Sheep; Vasoconstriction

2003
The hemodynamic effects of amyl nitrite and phenylephrine in patients with mitral stenosis and severe pulmonary hypertension.
    American heart journal, 1962, Volume: 64

    Topics: Amyl Nitrite; Hemodynamics; Humans; Hypertension; Hypertension, Pulmonary; Mitral Valve Stenosis; Phenylephrine

1962
Sildenafil alters calcium signaling and vascular tone in pulmonary arteries from chronically hypoxic rats.
    American journal of physiology. Lung cellular and molecular physiology, 2004, Volume: 287, Issue:3

    Topics: Angiotensin II; Animals; Caffeine; Calcium; Calcium Signaling; Chronic Disease; Disease Models, Animal; Hypertension, Pulmonary; Hypoxia; Male; Muscle, Smooth, Vascular; Phenylephrine; Phosphodiesterase Inhibitors; Piperazines; Pulmonary Artery; Purines; Rats; Rats, Wistar; Sildenafil Citrate; Sulfones; Vasoconstriction; Vasoconstrictor Agents

2004
Pulmonary artery smooth muscle activation attenuates arterial dysfunction during acute pulmonary hypertension.
    Journal of applied physiology (Bethesda, Md. : 1985), 2005, Volume: 98, Issue:2

    Topics: Acute Disease; Animals; Blood Pressure; Computer Simulation; Elasticity; Hypertension, Pulmonary; Models, Cardiovascular; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Pulmonary Artery; Severity of Illness Index; Sheep; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents; Viscosity

2005
Differential effects of phosphodiesterase-5 inhibitors on hypoxic pulmonary vasoconstriction and pulmonary artery cytokine expression.
    The Annals of thoracic surgery, 2006, Volume: 81, Issue:1

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Carbolines; Cyclic Nucleotide Phosphodiesterases, Type 5; Drug Evaluation, Preclinical; Gene Expression Regulation; Hypertension, Pulmonary; Hypoxia; Imidazoles; Interleukin-1; Isometric Contraction; Male; Phenylephrine; Phosphodiesterase Inhibitors; Piperazines; Pulmonary Artery; Purines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Sildenafil Citrate; Sulfones; Tadalafil; Triazines; Tumor Necrosis Factor-alpha; Vardenafil Dihydrochloride; Vasoconstriction

2006
Role of ATP-dependent potassium channels in pulmonary vascular tone of fetal lambs with congenital diaphragmatic hernia.
    Pediatric research, 2006, Volume: 60, Issue:5

    Topics: Adenosine Triphosphate; Animals; Female; Glyburide; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Hypertension, Pulmonary; Lung; Muscle, Smooth, Vascular; Phenylephrine; Pinacidil; Potassium Channels; Pregnancy; Pulmonary Circulation; Sheep, Domestic; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents

2006
Autoantibodies against G-protein-coupled receptors modulate heart mast cells.
    Cellular & molecular immunology, 2007, Volume: 4, Issue:2

    Topics: Adrenergic alpha-Agonists; Adult; Angiotensin II; Animals; Animals, Newborn; Autoantibodies; Cell Degranulation; Cell Differentiation; Cells, Cultured; Female; Humans; Hypertension; Hypertension, Pulmonary; Male; Mast Cells; Middle Aged; Myocardium; Phenylephrine; Pre-Eclampsia; Pregnancy; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Adrenergic, alpha-1; Receptors, G-Protein-Coupled; Time Factors

2007
Chronic hypoxia inhibits the antihypertensive effect of melatonin on pulmonary artery.
    International journal of cardiology, 2008, Jun-06, Volume: 126, Issue:3

    Topics: Animals; Chronic Disease; Disease Models, Animal; Hypertension, Pulmonary; Hypoxia; Male; Melatonin; Muscle, Smooth, Vascular; Phenylephrine; Pulmonary Artery; Random Allocation; Rats; Reference Values; Risk Factors; Sensitivity and Specificity; Vasoconstriction; Vasodilation

2008
Thromboxane A2 mimetic U-46619 induces systemic and pulmonary hypertension and delayed tachypnea in the goat.
    Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 77, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Blood Gas Analysis; Blood Pressure; Female; Goats; Hypertension; Hypertension, Pulmonary; Nitroprusside; Phenylephrine; Pressoreceptors; Prostaglandin Endoperoxides, Synthetic; Respiration Disorders; Respiratory Mechanics; Thromboxane A2; Vasoconstrictor Agents

1994
Chronic pulmonary hypertension in utero impairs endothelium-dependent vasodilation.
    The American journal of physiology, 1995, Volume: 268, Issue:1 Pt 2

    Topics: Acetylcholine; Animals; Aorta; Atrial Natriuretic Factor; Blood Pressure; Ductus Arteriosus; Endothelium; Female; Fetus; Gestational Age; Heart Rate, Fetal; Hemodynamics; Hypertension, Pulmonary; Phenylephrine; Pregnancy; Pulmonary Artery; Pulmonary Circulation; Reference Values; Sheep; Vascular Resistance; Vasodilation

1995
Altered left ventricular chamber stiffness and isovolumic relaxation in dogs with chronic pulmonary hypertension caused by emphysema.
    Circulation, 1993, Volume: 87, Issue:1

    Topics: Analysis of Variance; Animals; Chronic Disease; Diastole; Dogs; Elasticity; Emphysema; Heart; Hypertension, Pulmonary; Myocardial Contraction; Papain; Phenylephrine; Pressure; Radionuclide Angiography; Stroke Volume; Ventricular Function, Left

1993
Reactivity to alpha agonists is heightened in immature porcine pulmonary arteries.
    The Annals of thoracic surgery, 1996, Volume: 61, Issue:5

    Topics: Adrenergic alpha-Agonists; Aging; Animals; Endothelium, Vascular; Humans; Hypertension, Pulmonary; Muscle, Smooth; Phenylephrine; Pulmonary Artery; Swine; Vasoconstriction

1996
Nonpeptide endothelin receptor antagonists. VIII: attentuation of acute hypoxia-induced pulmonary hypertension in the dog.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:2

    Topics: Animals; Blood Pressure; Dogs; Endothelin Receptor Antagonists; Endothelin-1; Heart Rate; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Indans; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Pulmonary Artery; Vasoconstrictor Agents; Viper Venoms

1997
Decreased pulmonary arterial endothelium-dependent relaxation in heartworm-infected dogs with pulmonary hypertension.
    American journal of veterinary research, 1997, Volume: 58, Issue:2

    Topics: Animals; Blood Pressure; Carbachol; Dirofilariasis; Dog Diseases; Dogs; Endothelium, Vascular; Female; Hypertension, Pulmonary; In Vitro Techniques; Isometric Contraction; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Phenylephrine; Pulmonary Artery; Reference Values

1997
Garlic prevents hypoxic pulmonary hypertension in rats.
    The American journal of physiology, 1998, Volume: 275, Issue:2

    Topics: Acetylcholine; Animals; Blood Pressure; Endothelium, Vascular; Garlic; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Phenylephrine; Phytotherapy; Plant Extracts; Plants, Medicinal; Pulmonary Alveoli; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vasoconstriction

1998
Mechanism of failure in acute right ventricular hypertension.
    Surgical forum, 1979, Volume: 30

    Topics: Acute Disease; Animals; Coronary Circulation; Coronary Disease; Dogs; Heart Failure; Heart Ventricles; Hyperemia; Hypertension; Hypertension, Pulmonary; Phenylephrine

1979
The challenge of pulmonary hypertension.
    Chest, 1991, Volume: 99, Issue:1

    Topics: Humans; Hypertension, Pulmonary; Phenylephrine; Ventricular Function, Right

1991
The effects of phenylephrine on right ventricular performance in patients with pulmonary hypertension.
    Chest, 1990, Volume: 98, Issue:5

    Topics: Adult; Blood Pressure; Coronary Circulation; Female; Humans; Hypertension, Pulmonary; Male; Phenylephrine; Pulmonary Wedge Pressure; Ventricular Function, Right

1990
[Pharmacology of the pulmonary circulation].
    Schweizerische medizinische Wochenschrift, 1985, Sep-28, Volume: 115, Issue:39

    Topics: Adrenergic beta-Agonists; Epoprostenol; Fibrinolytic Agents; Humans; Hypertension, Pulmonary; Phenylephrine; Pulmonary Circulation; Pulmonary Embolism; Serotonin Antagonists; Theophylline; Thromboxane A2; Vascular Resistance; Vasodilator Agents

1985
Effects of phenylephrine on systemic and pulmonary artery pressure during sepsis-induced pulmonary hypertension in piglets.
    Developmental pharmacology and therapeutics, 1986, Volume: 9, Issue:4

    Topics: Animals; Blood Pressure; Cardiac Output; Contraceptives, Oral, Combined; Hypertension, Pulmonary; Phenylephrine; Pulmonary Circulation; Streptococcal Infections; Streptococcus agalactiae; Swine

1986