Page last updated: 2024-08-16

phenylephrine and Endotoxin Shock

phenylephrine has been researched along with Endotoxin Shock in 61 studies

Research

Studies (61)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (4.92)	18.7374
1990's	18 (29.51)	18.2507
2000's	19 (31.15)	29.6817
2010's	10 (16.39)	24.3611
2020's	11 (18.03)	2.80

Authors

Authors	Studies
Bosch, NA; Law, AC; Peterson, D; Walkey, AJ	1
Alenezi, FZ; AlQahtani, S; AlWehaibi, W; Arabi, YM; Arishi, H; Bin Humaid, F; Sadat, M; Tamim, H	1
AlQahtani, S; Arabi, YM; Arishi, H; Sadat, M	1
Chan, WS; Chiu, CT; Yeh, YC	1
AlQahtani, S; Arabi, Y; Arishi, H; Sadat, M	1
Bulloch, MN	1
Gu, WJ; He, D; Hong, L; Hu, H; Lu, X; Lyu, J; Yin, H; Zhang, L	1
Aitken, SL; Altshuler, J; Haiduc, M; Radparvar, S	1
Bauer, SR; Hawn, JM; Li, M; Mireles-Cabodevila, E; Reddy, AJ; Sacha, GL; Wang, X; Yerke, J	1
Cavanaugh, J; Patel, VV; Sullivan, JB	1
Keller, M; Magunia, H	1
Gershengorn, HB; Hua, M; Rubenfeld, G; Vail, E; Walkey, AJ; Wunsch, H	1
Alves, I; Duburcq, T; Favory, R; Guerry, MJ; Lemyze, M; Mathieu, D; Parmentier-Decrucq, E; Poissy, J	1
Assreuy, J; da Silva-Santos, JE; Gonçalves, RP; Guarido, KL	1
Avni, T; Grossman, A; Lador, A; Leibovici, L; Lev, S; Paul, M	1
Lu, S; Nguyen, HB; Possagnoli, I; Stokes, P	1
Bachetoni, A; D'Alessandro, M; Ertmer, C; Laderchi, A; Lange, M; Morelli, A; Orecchioni, A; Pietropaoli, P; Rehberg, S; Van Aken, H; Westphal, M	1
Hollenberg, SM	1
Guia, IL; Lessa, MA; Nacul, FE; Tibiriçá, E	1
Asfar, P; Collin, S; de la Bourdonnaye, M; Dron, AG; Lacolley, P; Levy, B; Meziani, F; Montemont, C; Sennoun, N	1
Lynch, C; Nemergut, EC; Thiele, RH	1
Ducrocq, N; Furmaniuk, A; Hekalo, Z; Kimmoun, A; Levy, B; Marie, PY; Maskali, F; Poussier, S	1
Bellissant, E; Donal, E; Lainé, F; Laviolle, B; Le Maguet, P	1
Garfield, RE; Okawa, T; Saade, GR; Vedernokov, YP	1
Barrière, E; Bernuau, D; Chauvelot-Moachon, L; Dargère, D; Guimont, MC; Lardeux, B; Lebrec, D; Moreau, R; Poirel, O; Tazi, KA; Urbanowicz, W	1
Anvari, K; Fatehi, M; Fatehi-Hassanabad, Z	1
Bollaert, PE; Levy, B; Longrois, D; Mallié, JP; Mansart, A; Seguin, C	1
BOOKRAJIAN, EN	1
LOB, H; POINSO, Y; SOULAYROL, R	1
Autore, G; Cuzzocrea, S; d'Emmanuele di Villa Bianca, R; Di Paola, R; Marzocco, S; Pinto, A; Sorrentino, R	1
Ashton, JL; Ashton, RC; Burchell, SA; Dahl, K; Landry, DW; Malay, MB; Oliver, JA; Savage, EB; Sciacca, RR	1
Hiltebrand, LB; Krejci, V; Sigurdsson, GH	1
van der Voort, PH	1
Bachetoni, A; D'Alessandro, M; Dünser, M; Ertmer, C; Guarracino, F; Lange, M; Morelli, A; Pietropaoli, P; Rehberg, S; Traber, DL; Van Aken, H; Westphal, M	1
Carnuccio, R; Di Rosa, M; Zingarelli, B	1
Higa, EM; McMurtry, IF; Niederberger, M; Raynolds, M; Schrier, RW; Weigert, AL	1
Baker, CH; Nessellroth, S; Ortiz-Tweed, M; Price, JM; Sutton, ET	1
Baker, CH; Price, JM; Sutton, ET; Zhou, Z	2
Haefeli, WE; Linder, L; Simper, D; Strobel, WM	1
Donaldson, LL; Myers, AK	1
Can, C; Cinar, MG; Evinç, A; Koşay, S; Ulker, S	1
Altavilla, D; Arlotta, M; Campo, GM; Caputi, AP; Saitta, A; Sardella, A; Serrano, M; Squadrito, F; Squadrito, G; Urna, G	1
Fischer, G; Georgieff, M; Kiefer, P; Radermacher, P; Reinelt, H; Vogt, J; Wachter, U	1
Ashton, RC; Landry, DW; Malay, MB; Townsend, RN	1
Cho, E; Ekelund, UE; Hare, JM; Harrison, RW; Kass, DA; Senzaki, H; Thakkar, RN	1
Cohen, RI; Davis, A; Loona, R; Scharf, SM; Shapir, Y	1
Annane, D; Bellissant, E	1
Bourreau, J; Shan, Q	1
Bordet, R; Corseaux, D; Jude, B; Lund, N; Pu, Q; Robin, E; Vallet, B; Wiel, E	1
Jaffa, AA; Margolius, HS; Morinelli, TA; Privitera, PJ; Webb, JG	1
Cherkaoui, S; De Backer, D; De Jongh, R; Vincent, JL; Vray, B; Zhang, H	1
Britt, LD; Prewitt, RL; Tan, BB	1
Ruffolo, RR	1
Attolino, RB	1
Cunnion, RE; Hollenberg, SM; Parrillo, JE	1
Bonfiglio, MF; Dasta, JF; Flancbaum, L; Gregory, JS; Reilley, TE; Townsend, MC	2
Auguet, M; Braquet, P; Chabrier, PE; Delaflotte, S	1
Bowles, HF; Mikhail, M; Morgan, GE; Thangathurai, D	1
Mills, LC; Moyer, JH	1

Reviews

4 review(s) available for phenylephrine and Endotoxin Shock

Article	Year
Vasopressors for the Treatment of Septic Shock: Systematic Review and Meta-Analysis. PloS one, 2015, Volume: 10, Issue:8 Topics: Epinephrine; Hemodynamics; Humans; Lypressin; Norepinephrine; Phenylephrine; Shock, Septic; Terlipressin; Treatment Outcome; Vasoconstrictor Agents; Vasopressins	2015
Inotrope and vasopressor therapy of septic shock. Critical care clinics, 2009, Volume: 25, Issue:4 Topics: Adrenergic Agents; Adrenergic alpha-Agonists; Animals; Cardiac Output; Cardiotonic Agents; Dopamine; Epinephrine; Hemodynamics; Humans; Phenylephrine; Regional Blood Flow; Resuscitation; Shock, Septic; Vasoconstrictor Agents; Vasopressins	2009
The clinical implications of isolated alpha(1) adrenergic stimulation. Anesthesia and analgesia, 2011, Volume: 113, Issue:2 Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Aortic Valve Stenosis; Brain Injuries; Carcinoid Tumor; Female; Humans; Hypotension; Intraoperative Complications; Lung Diseases; Perioperative Care; Phenylephrine; Pregnancy; Shock, Septic; Subarachnoid Hemorrhage; Tetralogy of Fallot; Ventricular Outflow Obstruction	2011
Fundamentals of receptor theory: basics for shock research. Circulatory shock, 1992, Volume: 37, Issue:2 Topics: Binding, Competitive; Drug Design; Naphazoline; Oxymetazoline; Phentolamine; Phenylephrine; Receptors, Adrenergic; Research Design; Shock, Septic; Signal Transduction; Therapeutic Equivalency	1992

Trials

5 trial(s) available for phenylephrine and Endotoxin Shock

Article	Year
Activated protein C improves macrovascular and microvascular reactivity in human severe sepsis and septic shock. Shock (Augusta, Ga.), 2013, Volume: 40, Issue:6 Topics: Adult; Aged; Arterial Pressure; Dose-Response Relationship, Drug; Female; Humans; Laser-Doppler Flowmetry; Male; Microcirculation; Middle Aged; Phenylephrine; Prospective Studies; Protein C; Sepsis; Shock, Septic; Skin; Vasoconstrictor Agents	2013
Phenylephrine versus norepinephrine for initial hemodynamic support of patients with septic shock: a randomized, controlled trial. Critical care (London, England), 2008, Volume: 12, Issue:6 Topics: Aged; Double-Blind Method; Female; Hemodynamics; Humans; Length of Stay; Male; Middle Aged; Norepinephrine; Phenylephrine; Prospective Studies; Shock, Septic; Vasoconstrictor Agents	2008
Low doses of fludrocortisone and hydrocortisone, alone or in combination, on vascular responsiveness to phenylephrine in healthy volunteers. British journal of clinical pharmacology, 2013, Volume: 75, Issue:2 Topics: Administration, Oral; Adult; Anti-Inflammatory Agents; Blood Pressure; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Drug Interactions; Fludrocortisone; Heart Rate; Humans; Hydrocortisone; Infusions, Intravenous; Injections, Intravenous; Male; Phenylephrine; Shock, Septic; Vasoconstrictor Agents; Young Adult	2013
Short-term effects of phenylephrine on systemic and regional hemodynamics in patients with septic shock: a crossover pilot study. Shock (Augusta, Ga.), 2008, Volume: 29, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Blood Pressure; Catecholamines; Cross-Over Studies; Female; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Norepinephrine; Phenylephrine; Pilot Projects; Prospective Studies; Sepsis; Shock, Septic; Treatment Outcome	2008
Low-dose vasopressin in the treatment of vasodilatory septic shock. The Journal of trauma, 1999, Volume: 47, Issue:4 Topics: Blood Pressure; Cardiac Output; Cardiotonic Agents; Dopamine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Norepinephrine; Phenylephrine; Pulmonary Wedge Pressure; Shock, Septic; Survival Analysis; Vascular Resistance; Vasoconstrictor Agents; Vasopressins	1999

Other Studies

52 other study(ies) available for phenylephrine and Endotoxin Shock

Article	Year
Comparison of Heart Rate After Phenylephrine vs Norepinephrine Initiation in Patients With Septic Shock and Atrial Fibrillation. Chest, 2022, Volume: 162, Issue:4 Topics: Atrial Fibrillation; Bradycardia; Heart Rate; Humans; Norepinephrine; Phenylephrine; Sepsis; Shock, Septic; Vasoconstrictor Agents	2022
Combination of norepinephrine with phenylephrine versus norepinephrine with vasopressin in critically ill patients with septic shock: A retrospective study. Journal of critical care, 2022, Volume: 72 Topics: Adult; Critical Illness; Humans; Norepinephrine; Phenylephrine; Retrospective Studies; Shock, Septic; Vasoconstrictor Agents; Vasopressins	2022
Author reply: Combination of norepinephrine with phenylephrine versus norepinephrine with vasopressin in critically ill patients with septic shock: A retrospective study. Journal of critical care, 2023, Volume: 73 Topics: Critical Illness; Humans; Norepinephrine; Phenylephrine; Retrospective Studies; Shock, Septic; Vasoconstrictor Agents; Vasopressins	2023
Letter to the editor: "Combination of norepinephrine with phenylephrine versus norepinephrine with vasopressin in critically ill patients with septic shock: A retrospective study". Journal of critical care, 2023, Volume: 73 Topics: Critical Illness; Humans; Norepinephrine; Phenylephrine; Retrospective Studies; Shock, Septic; Vasoconstrictor Agents; Vasopressins	2023
Author's response: "Combination of norepinephrine with phenylephrine versus norepinephrine with vasopressin in critically ill patients with septic shock: A retrospective study". Journal of critical care, 2023, Volume: 74 Topics: Critical Illness; Humans; Norepinephrine; Phenylephrine; Retrospective Studies; Shock, Septic; Vasoconstrictor Agents; Vasopressins	2023
Letter to the editor: "Combination of norepinephrine with phenylephrine versus norepinephrine with vasopressin in critically ill patients with septic shock: A retrospective study". Journal of critical care, 2023, Volume: 74 Topics: Critical Illness; Humans; Norepinephrine; Phenylephrine; Retrospective Studies; Shock, Septic; Vasoconstrictor Agents; Vasopressins	2023
Norepinephrine combined with phenylephrine versus norepinephrine in patients with septic shock: a retrospective cohort study. BMC infectious diseases, 2023, Apr-07, Volume: 23, Issue:1 Topics: Adult; Blood Pressure; Humans; Norepinephrine; Phenylephrine; Retrospective Studies; Shock, Septic	2023
Does Switching Norepinephrine to Phenylephrine in Septic Shock Complicated by Atrial Fibrillation With Rapid Ventricular Response Improve Time to Rate Control? Journal of intensive care medicine, 2021, Volume: 36, Issue:2 Topics: Atrial Fibrillation; Drug Substitution; Humans; Intensive Care Units; Norepinephrine; Phenylephrine; Retrospective Studies; Shock, Septic	2021
Effect of Phenylephrine Push Before Continuous Infusion Norepinephrine in Patients With Septic Shock. Chest, 2021, Volume: 159, Issue:5 Topics: Administration, Intravenous; APACHE; Cardiotonic Agents; Female; Humans; Injections, Intravenous; Male; Middle Aged; Norepinephrine; Organ Dysfunction Scores; Phenylephrine; Propensity Score; Retrospective Studies; Shock, Septic	2021
Analysis of Mortality in Patients Treated With Phenylephrine in Septic Shock. Journal of pharmacy practice, 2023, Volume: 36, Issue:1 Topics: Adult; Humans; Intensive Care Units; Norepinephrine; Phenylephrine; Retrospective Studies; Shock, Septic; Vasoconstrictor Agents	2023
[Vasopressors: Physiology, Pharmacology and Clinical Applications]. Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 2021, Volume: 56, Issue:6 Topics: Humans; Norepinephrine; Phenylephrine; Shock; Shock, Septic; Vasoconstrictor Agents	2021
Association Between US Norepinephrine Shortage and Mortality Among Patients With Septic Shock. JAMA, 2017, 04-11, Volume: 317, Issue:14 Topics: Aged; Databases, Factual; Female; Hospital Mortality; Humans; Male; Middle Aged; Norepinephrine; Outcome Assessment, Health Care; Phenylephrine; Retrospective Studies; Shock, Septic; United States; Vasoconstrictor Agents	2017
Gender-specific differences in the in situ cardiac function of endotoxemic rats detected by pressure-volume catheter. Shock (Augusta, Ga.), 2014, Volume: 42, Issue:5 Topics: Animals; Cardiac Catheterization; Endotoxemia; Female; Heart Diseases; Heart Rate; Hemodynamics; Lipopolysaccharides; Male; Phenylephrine; Rats, Wistar; Sex Characteristics; Shock, Septic; Stroke Volume; Vasoconstrictor Agents	2014
Comparative Effectiveness of Second Vasoactive Agents in Septic Shock Refractory to Norepinephrine. Journal of intensive care medicine, 2017, Volume: 32, Issue:7 Topics: Aged; Comparative Effectiveness Research; Dobutamine; Dopamine; Drug Therapy, Combination; Female; Hospital Mortality; Humans; Male; Middle Aged; Norepinephrine; Phenylephrine; Retrospective Studies; Shock, Septic; Survival Analysis; Treatment Outcome; Vasoconstrictor Agents; Vasopressins	2017
The effects of vasoactive drugs on intestinal functional capillary density in endotoxemic rats: intravital video-microscopy analysis. Anesthesia and analgesia, 2010, Feb-01, Volume: 110, Issue:2 Topics: Animals; Capillaries; Cardiotonic Agents; Dobutamine; Dopamine; Endotoxemia; Epinephrine; Escherichia coli Infections; Intestine, Small; Lactic Acid; Lipopolysaccharides; Mesenteric Veins; Microcirculation; Microscopy, Video; Norepinephrine; Phenylephrine; Rats; Rats, Inbred WKY; Shock, Septic; Vasoconstrictor Agents	2010
Vascular ATP-sensitive potassium channels are over-expressed and partially regulated by nitric oxide in experimental septic shock. Intensive care medicine, 2011, Volume: 37, Issue:5 Topics: Animals; Blotting, Western; France; KATP Channels; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Nitric Oxide; Phenylephrine; Polymerase Chain Reaction; Rats; Rats, Wistar; Shock, Septic	2011
Comparison of equipressor doses of norepinephrine, epinephrine, and phenylephrine on septic myocardial dysfunction. Anesthesiology, 2012, Volume: 116, Issue:5 Topics: Adenine Nucleotides; Animals; Arrhythmias, Cardiac; Blood Pressure; Cardiac Output; Catheterization; Cecum; Epinephrine; Heart Diseases; Heart Rate; Lactic Acid; Ligation; Male; Myocardial Contraction; Myocardium; Norepinephrine; Oxygen Consumption; Peritonitis; Phenylephrine; Positron-Emission Tomography; Rats; Rats, Wistar; Shock, Septic; Stroke Volume; Vasoconstrictor Agents	2012
Gender differences in contractile and relaxing responses of aortic rings from lipopolysaccharide-treated rats. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2002, Volume: 16, Issue:3 Topics: Acetylcholine; Animals; Aorta; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Gram-Negative Bacteria; Hydrazines; Inhibitory Concentration 50; Injections, Intraperitoneal; Lipopolysaccharides; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitrogen Oxides; Oxyhemoglobins; Phenylephrine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Sex; Shock, Septic	2002
Terlipressin inhibits in vivo aortic iNOS expression induced by lipopolysaccharide in rats with biliary cirrhosis. Hepatology (Baltimore, Md.), 2002, Volume: 36, Issue:5 Topics: Alanine Transaminase; Animals; Aorta, Thoracic; Blood Pressure; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Hypotension; Lipopolysaccharides; Liver Cirrhosis, Biliary; Lypressin; Lysine; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phenylephrine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Shock, Septic; Terlipressin; Tumor Necrosis Factor-alpha; Vasoconstrictor Agents	2002
The beneficial effects of protein tyrosine kinase inhibition on the circulatory failure induced by endotoxin in the rat. Shock (Augusta, Ga.), 2002, Volume: 18, Issue:5 Topics: Animals; Drug Interactions; Endotoxins; Enzyme Inhibitors; Genistein; Hemodynamics; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Phenylephrine; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Shock, Septic; Splanchnic Circulation; Sympathetic Nervous System; Vasoconstriction	2002
Hemodynamic effects of early versus late glucocorticosteroid administration in experimental septic shock. Shock (Augusta, Ga.), 2003, Volume: 19, Issue:1 Topics: Adrenergic alpha-Agonists; Animals; Catecholamines; Cyclic AMP; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epinephrine; Glucocorticoids; Hemodynamics; Isoproterenol; Lactic Acid; Male; Myocardium; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Norepinephrine; Phenylephrine; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Catecholamine; Sepsis; Shock, Septic; Signal Transduction; Time Factors	2003
SEPTIC ABORTION WITH BACTEREMIC SHOCK. The Journal of the Medical Society of New Jersey, 1963, Volume: 60 Topics: Abortion, Septic; Chloramphenicol; Female; Humans; Hydrocortisone; Metaraminol; Norepinephrine; Oxygen Inhalation Therapy; Oxytocin; Penicillins; Phenylephrine; Pregnancy; Sepsis; Shock; Shock, Septic; Streptomycin; Water-Electrolyte Balance	1963
[INCIDENTS DUE TO DRUG INTERFERENCE WITH MONOAMINE OXIDASE INHIBITORS]. Revue de neuropsychiatrie infantile et d'hygiene mentale de l'enfance, 1964, Volume: 12 Topics: Amphetamine; Amphetamines; Coma; Hypotension; Imipramine; Meperidine; Monoamine Oxidase Inhibitors; Nikethamide; Phenylephrine; Shock; Shock, Septic; Toxicology	1964
Melatonin prevents lipopolysaccharide-induced hyporeactivity in rat. Journal of pineal research, 2004, Volume: 36, Issue:3 Topics: Animals; Aorta; Endothelium, Vascular; In Vitro Techniques; Lipopolysaccharides; Male; Melatonin; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxynitrous Acid; Phenylephrine; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Reactive Oxygen Species; Shock, Septic; Vasoconstriction	2004
Heterogeneity of the vasoconstrictor effect of vasopressin in septic shock. Critical care medicine, 2004, Volume: 32, Issue:6 Topics: Animals; Blood Pressure; Cardiac Output; Carotid Arteries; Cerebrovascular Circulation; Female; Heart Rate; Iliac Artery; Mesenteric Arteries; Phenylephrine; Pulmonary Artery; Renal Artery; Shock, Septic; Swine; Vasoconstriction; Vasoconstrictor Agents; Vasopressins	2004
Effects of epinephrine, norepinephrine, and phenylephrine on microcirculatory blood flow in the gastrointestinal tract in sepsis. Critical care medicine, 2006, Volume: 34, Issue:5 Topics: Analysis of Variance; Animals; Blood Pressure; Cross-Over Studies; Epinephrine; Hemodynamics; Intestines; Liver; Microcirculation; Norepinephrine; Pancreas; Phenylephrine; Random Allocation; Shock, Septic; Splanchnic Circulation; Swine; Vasoconstrictor Agents	2006
The incomplete puzzle of vasoactive medication in (abdominal) sepsis. Critical care medicine, 2006, Volume: 34, Issue:5 Topics: Animals; Blood Pressure; Humans; Microcirculation; Phenylephrine; Shock, Septic; Splanchnic Circulation; Swine; Vasoconstrictor Agents	2006
Cloricromene inhibits the induction of nitric oxide synthase. European journal of pharmacology, 1993, Oct-19, Volume: 243, Issue:2 Topics: Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Cell Line; Chromonar; Depression, Chemical; Endotoxins; Enzyme Induction; In Vitro Techniques; Macrophages; Male; Mice; Muscle Tonus; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Phenylephrine; Rats; Rats, Wistar; Shock, Septic	1993
Expression and preferential inhibition of inducible nitric oxide synthase in aortas of endotoxemic rats. Journal of the American Society of Nephrology : JASN, 1995, Volume: 5, Issue:12 Topics: Animals; Aorta, Thoracic; DNA, Complementary; Enzyme Induction; Guanidines; Lipopolysaccharides; Male; Muscle Contraction; Muscle Proteins; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Phenylephrine; Rats; Rats, Sprague-Dawley; Shock, Septic	1995
Attenuation of arteriolar alpha 2-adrenoceptor sensitivity during endotoxemia. The American journal of physiology, 1994, Volume: 267, Issue:6 Pt 2 Topics: Animals; Arterioles; Clonidine; Dioxanes; Endotoxins; Escherichia coli; Idazoxan; Male; Muscles; Phenylephrine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Shock, Septic; Vasoconstriction	1994
Effect of muscle length on the in vitro comparison of femoral arteries before and after endotoxin shock. The American journal of physiology, 1993, Volume: 265, Issue:4 Pt 2 Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Endotoxins; Femoral Artery; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Phenylephrine; Rats; Rats, Sprague-Dawley; Reference Values; Shock, Septic; Stress, Mechanical; Vasoconstriction	1993
In vitro femoral arterial responses to vasoconstrictor and vasodilator agents in endotoxin shock. Life sciences, 1994, Volume: 54, Issue:1 Topics: Acetylcholine; Animals; Arginine; Arginine Vasopressin; Bradykinin; Femoral Artery; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Phenylephrine; Potassium Chloride; Rats; Rats, Wistar; Shock, Septic; Vasoconstrictor Agents; Vasodilator Agents	1994
Indirect evidence for stimulation of nitric oxide release by tumour necrosis factor-alpha in human veins in vivo. Cardiovascular research, 1995, Volume: 30, Issue:6 Topics: Adult; Arginine; Dose-Response Relationship, Drug; Humans; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Shock, Septic; Tumor Necrosis Factor-alpha; Vasodilation; Veins	1995
Effect of pharmacological agonists on contractile responses in aortic rings derived from endotoxaemic rats. Journal of veterinary pharmacology and therapeutics, 1996, Volume: 19, Issue:5 Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Albuterol; Analysis of Variance; Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Dinoprost; Dose-Response Relationship, Drug; Endothelium, Vascular; Imidazoles; Injections, Intravenous; Isometric Contraction; Lipopolysaccharides; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Phenylephrine; Potassium Chloride; Rats; Rats, Wistar; Shock, Septic; Vasodilator Agents	1996
Effects of MK-886, a leukotriene biosynthesis inhibitor, in a rabbit model of endotoxic shock. European journal of pharmacology, 1998, Jun-05, Volume: 350, Issue:2-3 Topics: Algorithms; Animals; Blood Pressure; Endotoxins; Hemodynamics; Indoles; Leukotrienes; Lipopolysaccharides; Lipoxygenase Inhibitors; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Phenylephrine; Rabbits; Shock, Septic; Vasoconstrictor Agents	1998
Inhibition of tumour necrosis factor and reversal of endotoxin-induced shock by U-83836E, a 'second generation' lazaroid in rats. British journal of pharmacology, 1998, Volume: 124, Issue:6 Topics: Animals; Aorta; Blood Pressure; Cells, Cultured; Chromans; In Vitro Techniques; Lipopolysaccharides; Macrophages, Peritoneal; Male; Malondialdehyde; Pertussis Toxin; Phenylephrine; Piperazines; Rats; Rats, Sprague-Dawley; Shock, Septic; Steroids; Tumor Necrosis Factor-alpha; Virulence Factors, Bordetella	1998
Impact of exogenous beta-adrenergic receptor stimulation on hepatosplanchnic oxygen kinetics and metabolic activity in septic shock. Critical care medicine, 1999, Volume: 27, Issue:2 Topics: Aged; Combined Modality Therapy; Hemodynamics; Humans; Liver; Middle Aged; Norepinephrine; Oxygen Consumption; Phenylephrine; Prospective Studies; Receptors, Adrenergic, beta; Shock, Septic; Splanchnic Circulation; Stimulation, Chemical	1999
Relative contribution of preload and afterload to the reduction in cardiac output caused by nitric oxide synthase inhibition with L-N(G)-methylarginine hydrochloride 546C88. Critical care medicine, 2000, Volume: 28, Issue:5 Topics: Animals; Blood Pressure; Cardiac Output; Dogs; Endothelium, Vascular; Enzyme Inhibitors; Humans; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Shock, Septic; Vascular Resistance; Vasoconstrictor Agents; Ventricular Function, Left	2000
Comparison between selective and nonselective nitric oxide synthase inhibition and phenylephrine in normal and endotoxic swine. Critical care medicine, 2000, Volume: 28, Issue:9 Topics: Animals; Cardiotonic Agents; Enzyme Inhibitors; Female; Hemodynamics; Isothiuronium; Lipopolysaccharides; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenylephrine; Shock, Septic; Swine	2000
Effect of hydrocortisone on phenylephrine--mean arterial pressure dose-response relationship in septic shock. Clinical pharmacology and therapeutics, 2000, Volume: 68, Issue:3 Topics: Analysis of Variance; Anti-Inflammatory Agents; Baroreflex; Blood Pressure; Cardiotonic Agents; Case-Control Studies; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Hydrocortisone; Infusions, Intravenous; Male; Middle Aged; Phenylephrine; Prognosis; Severity of Illness Index; Shock, Septic	2000
Cardiac and vascular effects of nitric oxide synthase inhibition in lipopolysaccharide-treated rats. European journal of pharmacology, 2000, Oct-13, Volume: 406, Issue:2 Topics: Animals; Aorta; Calcium; Enzyme Inhibitors; Guanidines; Heart; In Vitro Techniques; Lipopolysaccharides; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Shock, Septic; Vasoconstriction	2000
Effect of L-arginine on endothelial injury and hemostasis in rabbit endotoxin shock. Journal of applied physiology (Bethesda, Md. : 1985), 2000, Volume: 89, Issue:5 Topics: Acetylcholine; Animals; Arginine; Blood Gas Analysis; Calcimycin; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Hemostasis; Ionophores; Lipopolysaccharides; Male; Monocytes; NG-Nitroarginine Methyl Ester; Nitroprusside; Phenylephrine; Rabbits; Shock, Septic; Thromboplastin; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Weight Loss	2000
A metabolic fragment of bradykinin, Arg-Pro-Pro-Gly-Phe, protects against the deleterious effects of lipopolysaccharide in rats. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 296, Issue:1 Topics: Animals; Aorta, Thoracic; Blood Pressure; Bradykinin; Heart Rate; In Vitro Techniques; Lipopolysaccharides; Male; Muscle Contraction; Muscle, Smooth, Vascular; Peptide Fragments; Phenylephrine; Rats; Rats, Sprague-Dawley; Shock, Septic; Vasoconstrictor Agents	2001
Effects of alpha - and beta -adrenergic stimulation on hepatosplanchnic perfusion and oxygen extraction in endotoxic shock. Critical care medicine, 2001, Volume: 29, Issue:3 Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Blood Flow Velocity; Cardiac Output; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Drug Monitoring; Female; Intestinal Mucosa; Isoproterenol; Male; Oxygen Consumption; Phenylephrine; Prospective Studies; Random Allocation; Shock, Septic; Splanchnic Circulation; Stroke Volume; Time Factors; Tumor Necrosis Factor-alpha; Vascular Resistance	2001
Interleukin-10 prevents loss of tone of rat skeletal muscle arterioles exposed to endotoxin. The Journal of surgical research, 2001, Volume: 100, Issue:1 Topics: Acetylcholine; Animals; Aorta, Thoracic; Arterioles; Endotoxins; In Vitro Techniques; Interleukin-10; Male; Muscle, Skeletal; Phenylephrine; Rats; Rats, Sprague-Dawley; Shock, Septic; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents	2001
Comment: high-dose phenylephrine infusion. The Annals of pharmacotherapy, 1992, Volume: 26, Issue:6 Topics: Humans; Infusions, Intravenous; Phenylephrine; Shock, Septic	1992
The effect of tumor necrosis factor on vascular smooth muscle. In vitro studies using rat aortic rings. Chest, 1991, Volume: 100, Issue:4 Topics: Animals; Aorta, Thoracic; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Interleukin-1; Interleukin-2; Interleukin-6; Male; Muscle, Smooth, Vascular; Phenylephrine; Rats; Shock, Septic; Tumor Necrosis Factor-alpha; Vasodilation	1991
Experience with phenylephrine as a component of the pharmacologic support of septic shock. Critical care medicine, 1991, Volume: 19, Issue:11 Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Hypotension; Male; Middle Aged; Oxygen Consumption; Phenylephrine; Retrospective Studies; Shock, Septic; Vasodilation	1991
[Loss of contractile stability induced by phenylephrine and endothelin in the aorta of rats treated with endotoxin]. Archives des maladies du coeur et des vaisseaux, 1990, Volume: 83, Issue:8 Topics: Animals; Aorta, Thoracic; Endothelins; Endothelium, Vascular; Endotoxins; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Phorbol 12,13-Dibutyrate; Potassium Chloride; Rats; Rats, Inbred Strains; Shock, Septic	1990
Management of supraventricular tachycardia in septic patients. Anaesthesia, 1990, Volume: 45, Issue:9 Topics: Drug Therapy, Combination; Humans; Phenylephrine; Shock, Septic; Tachycardia, Supraventricular; Verapamil	1990
High-dose phenylephrine infusion in the hemodynamic support of septic shock. DICP : the annals of pharmacotherapy, 1990, Volume: 24, Issue:10 Topics: Acute Kidney Injury; Aged; Blood Pressure; Candidiasis; Dopamine; Hemodynamics; Humans; Infusions, Intravenous; Male; Phenylephrine; Shock, Septic; Time Factors	1990
Vasopressors for treating shock. Postgraduate medicine, 1974, Volume: 56, Issue:2 Topics: Bacteria; Chloramphenicol; Epinephrine; Humans; Isoproterenol; Metaraminol; Methoxamine; Morphine; Myocardial Infarction; Nalorphine; Norepinephrine; Phenoxybenzamine; Phenylephrine; Shock; Shock, Septic; Streptomycin; Tetracycline; Vasoconstrictor Agents	1974