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phenylephrine and Diabetes Mellitus, Adult-Onset

phenylephrine has been researched along with Diabetes Mellitus, Adult-Onset in 44 studies

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (6.82)18.2507
2000's21 (47.73)29.6817
2010's20 (45.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bansal, S; Chopra, K1
Hasegawa, M; Hida, M; Kobayashi, T; Matsumoto, T; Narimatsu, H; Taguchi, K1
Ando, M; Iguchi, M; Kobayashi, S; Kobayashi, T; Kojima, M; Matsumoto, T; Taguchi, K; Takayanagi, K1
Kasono, K; Nobe, K; Ohtake, K; Takenouchi, Y1
Fassot, C; Guihot, AL; Henrion, D; Loufrani, L; Maquigneau, M; Toutain, B; Vessières, E1
Hashimoto, T; Honda, K; Kasono, K; Nobe, K; Takenouchi, Y1
Coffman, KL; Foote, C; Ji, T; Martinez-Lemus, LA; Ramirez-Perez, FI; Rivera, RM; Schenewerk, AL1
Ait-Aissa, K; Ali, M; Kassan, M; Matrougui, K; Trebak, M1
Ando, M; Iguchi, M; Kobayashi, T; Matsumoto, T; Taguchi, K; Watanabe, S; Yamada, K1
Liang, J; Ma, S; Pan, C; Qin, W; Ren, B; Wang, L; Wang, S; Wu, F; Zeng, B1
Kobayashi, T; Matsumoto, T; Taguchi, K; Watanabe, S1
Nakano, T; Takahashi, Y; Wakabayashi, I1
Harvey, JN; Nurmikko, TJ; Schmiedel, O; Schroeter, ML; Whitaker, R1
Ishida, K; Kamata, K; Kobayashi, T; Matsumoto, T; Taguchi, K1
Burnier, MN; Coblentz, J; Fernandes, BF; Motta, MM; Vianna, RN1
Anan, F; Hara, M; Murozono, Y; Nakagawa, M; Okada, N; Saikawa, T; Shinohara, T; Takahashi, N; Wakisaka, O; Yoshimatsu, H; Yufu, K1
Carneiro, FS; Carneiro, ZN; Ergul, A; Giachini, FR; Lima, VV; Tostes, RC; Webb, RC1
Ahmed, KA; Akaike, T; Dong, YF; Fukuda, M; Kataoka, K; Kim-Mitsuyama, S; Nakamura, T; Nako, H; Sawa, T; Tokutomi, Y; Toyama, K; Yamamoto, E1
Chia, E; Kagota, S; McGuire, JJ1
Bratz, IN; Damron, DS; Guarini, G; Haney, RM; Meszaros, JG; Ohanyan, VA; Raman, P; Talasila, PK; Thodeti, CK1
Kamata, K; Kobayashi, T; Matsumoto, T; Nemoto, S; Taguchi, K1
Fakher, S; Khalili, A; Khosravi, MB; Nekooeian, AA1
Nabbi, R; Riess, ML; Woehlck, HJ1
Kamata, K; Kobayashi, T; Matsumoto, T; Taguchi, K1
Ajayi, AA; Cory, J; Hayes, BE; Hercule, H; Oyekan, AO1
Kamata, K; Kobayashi, T; Matsumoto, T; Wakabayashi, K1
Fujita, N; Goto, F; Kadoi, Y; Saito, S1
Huisamen, B; Lochner, A; Upton, J1
Chung, AW; Luo, H; McManus, BM; Okon, EB; Padilla, E; Rauniyar, P; Tejerina, T; van Breemen, C1
Biswas, NR; Datta, S; Deepak, KK; Garg, SP; Menon, V; Saxena, R; Tandon, R1
Anderson, TJ; Berger, JP; Howarth, AG; Jiang, Y; Pannirselvam, M; Severson, D; Triggle, CR; Wiehler, WB1
Fowler, A; Galiñanes, M; Hassouna, A; Loubani, M; Matata, BM; Standen, NB1
Dreher, KL; Kelly, SE; Proctor, SD; Russell, JC1
Grant, MB; Guberski, DL; Ito, I; Jarajapu, YP; Knot, HJ1
Falcone, JC; Fleming, JT; Joshua, IG; Passmore, JC; Rodriguez, WE; Tyagi, N; Tyagi, SC1
Ari, N; Aslamaci, S; Irat, AM; Karasu, C1
Bender, SB; Klabunde, RE1
Carneiro, FS; Carneiro, ZN; Giachini, FRC; Inscho, EW; Leite, R; Lima, VV; Tostes, RC; Webb, RC1
Asbun-Bojalil, J; Castillo-Henkel, C; Castillo-Hernández, MC; Cervantes-Cruz, J; Cruz-Domínguez, MP; Miliar-García, A; Montes-Cortés, DH; Reséndiz-Ramírez, AC; Villalobos-Molina, R1
Belmadani, S; Boulares, HA; Gonzalez-Villalobos, RA; Matrougui, K; Palen, DI1
Chitaley, K; Luttrell, IP; Parks, WC; Starcher, B; Swee, M1
Turner, NC; White, P1
Cautela, G; Romano, AM; Russo, S; Scotto di Uccio, F; Scotto di Uccio, V1
Boatright, R; Bower, A; Fulk, GW; McBride, K1

Trials

3 trial(s) available for phenylephrine and Diabetes Mellitus, Adult-Onset

ArticleYear
Alpha adrenoceptor agonist-induced microcirculatory oscillations are reduced in diabetic neuropathy.
    Microvascular research, 2008, Volume: 76, Issue:2

    Topics: Adrenergic alpha-Agonists; Aged; Albuminuria; Arm; Cluster Analysis; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Female; Foot; Fourier Analysis; Glycated Hemoglobin; Humans; Hyperemia; Hypotension, Orthostatic; Insulin Resistance; Laser-Doppler Flowmetry; Logistic Models; Male; Metabolic Syndrome; Microcirculation; Middle Aged; Phenylephrine; Sensory Thresholds; Skin; Valsalva Maneuver

2008
Comparison between obtained mydriasis in type 2 diabetics and non-diabetic patients.
    Current eye research, 2009, Volume: 34, Issue:11

    Topics: Diabetes Mellitus, Type 2; Drug Combinations; Humans; Middle Aged; Muscle, Smooth; Mydriatics; Ophthalmoscopy; Phenylephrine; Prospective Studies; Pupil; Tropicamide

2009
The effect of diabetes on the interrelationship between jugular venous oxygen saturation responsiveness to phenylephrine infusion and cerebrovascular carbon dioxide reactivity.
    Anesthesia and analgesia, 2004, Volume: 99, Issue:2

    Topics: Aged; Anesthesia; Blood Gas Analysis; Carbon Dioxide; Cerebrovascular Circulation; Coronary Artery Bypass; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Hemodynamics; Humans; Infusions, Intravenous; Jugular Veins; Male; Middle Aged; Oxygen; Phenylephrine; Vasoconstrictor Agents

2004

Other Studies

41 other study(ies) available for phenylephrine and Diabetes Mellitus, Adult-Onset

ArticleYear
Selective ER-α agonist alleviates vascular endothelial dysfunction in ovariectomized type 2 diabetic rats.
    Molecular and cellular endocrinology, 2018, 01-15, Volume: 460

    Topics: Acetylcholine; Animals; Aorta; Biomarkers; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endothelium, Vascular; Estradiol; Estrogen Receptor alpha; Female; Glyburide; Inflammation; Lipids; Nitric Oxide Synthase Type III; Nitriles; Nitroprusside; Organ Size; Ovariectomy; Oxidative Stress; Phenols; Phenylephrine; Propionates; Pyrazoles; Rats, Sprague-Dawley; Uterus

2018
Suppression of GRK2 expression reduces endothelial dysfunction by restoring glucose homeostasis.
    Scientific reports, 2017, 08-16, Volume: 7, Issue:1

    Topics: Animals; Aorta; Cells, Cultured; Diabetes Mellitus, Type 2; Endothelium, Vascular; G-Protein-Coupled Receptor Kinase 2; Glucose; Homeostasis; Humans; Liver; Male; Mice, Inbred ICR; Mice, Obese; Phenylephrine; RNA Interference; Vasoconstriction; Vasoconstrictor Agents

2017
Alteration of Vascular Responsiveness to Uridine Adenosine Tetraphosphate in Aortas Isolated from Male Diabetic Otsuka Long-Evans Tokushima Fatty Rats: The Involvement of Prostanoids.
    International journal of molecular sciences, 2017, Nov-09, Volume: 18, Issue:11

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Chronic Disease; Cyclooxygenase Inhibitors; Diabetes Mellitus, Type 2; Dinucleoside Phosphates; Disease Models, Animal; Endothelium, Vascular; Male; Nitric Oxide; Phenylephrine; Prostaglandins; Rats; Rats, Inbred OLETF

2017
Eicosapentaenoic acid ethyl ester improves endothelial dysfunction in type 2 diabetic mice.
    Lipids in health and disease, 2018, May-22, Volume: 17, Issue:1

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Glucose; Cardiovascular Agents; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Eicosapentaenoic Acid; Endothelium, Vascular; Insulin; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle Contraction; Nitroprusside; Phenylephrine; Tissue Culture Techniques; Vasodilation

2018
COX-2-derived prostanoids and oxidative stress additionally reduce endothelium-mediated relaxation in old type 2 diabetic rats.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Acetylcholine; Animals; Blood Glucose; Blood Pressure; Body Weight; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endothelium, Vascular; Male; Oxidative Stress; Phenylephrine; Prostaglandins; Rats; Reactive Oxygen Species; Vasoconstriction; Vasodilation

2013
Two types of overcontraction are involved in intrarenal artery dysfunction in type II diabetic mouse.
    The Journal of pharmacology and experimental therapeutics, 2014, Volume: 351, Issue:1

    Topics: Acetophenones; Animals; Benzopyrans; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Male; Mice; Mice, Obese; Phenylephrine; Protein Kinase C; Protein Kinase Inhibitors; Renal Artery; Renal Circulation; Vasoconstriction; Vasoconstrictor Agents

2014
Effects of the use of assisted reproductive technologies and an obesogenic environment on resistance artery function and diabetes biomarkers in mice offspring.
    PloS one, 2014, Volume: 9, Issue:11

    Topics: Acetylcholine; Animals; Biomarkers; Diabetes Mellitus, Type 2; Diet, Western; Female; Male; Mesenteric Arteries; Mice, Inbred Strains; Obesity; Phenylephrine; Pregnancy; Prenatal Exposure Delayed Effects; Reproductive Techniques, Assisted; Vasoconstriction; Vasodilation

2014
Augmented EGF receptor tyrosine kinase activity impairs vascular function by NADPH oxidase-dependent mechanism in type 2 diabetic mouse.
    Biochimica et biophysica acta, 2015, Volume: 1853, Issue:10 Pt A

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Cytochrome b Group; Diabetes Mellitus, Type 2; Diabetic Angiopathies; ErbB Receptors; Mice; Mice, Knockout; NADPH Oxidase 4; NADPH Oxidases; Phenylephrine; Quinazolines; Tyrphostins; Vasoconstriction; Vasodilation

2015
Diabetes and Age-Related Differences in Vascular Function of Renal Artery: Possible Involvement of Endoplasmic Reticulum Stress.
    Rejuvenation research, 2016, Volume: 19, Issue:1

    Topics: Acetylcholine; Aging; Animals; bcl-2-Associated X Protein; Biomarkers; Diabetes Mellitus, Type 2; Dinucleoside Phosphates; Endoplasmic Reticulum Stress; Endothelium, Vascular; Group IV Phospholipases A2; Male; Nitroprusside; Phenylephrine; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred OLETF; Renal Artery; Sirtuin 1; Taurochenodeoxycholic Acid; Vasodilation

2016
Apigenin and naringenin regulate glucose and lipid metabolism, and ameliorate vascular dysfunction in type 2 diabetic rats.
    European journal of pharmacology, 2016, Feb-15, Volume: 773

    Topics: Animals; Anti-Inflammatory Agents; Aorta, Thoracic; Apigenin; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Fasting; Flavanones; Glucose Tolerance Test; Human Umbilical Vein Endothelial Cells; Humans; Insulin Resistance; Intercellular Adhesion Molecule-1; Lipid Metabolism; Lipid Peroxidation; Male; NF-kappa B; Nitric Oxide; Phenylephrine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Vasoconstriction; Vasodilation

2016
Relationship between PDK1 and contraction in carotid arteries in Goto-Kakizaki rat, a spontaneous type 2 diabetic animal model.
    Canadian journal of physiology and pharmacology, 2017, Volume: 95, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Phosphoinositide-Dependent Protein Kinases; Animals; Carotid Arteries; Chronic Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Models, Animal; Indazoles; Male; Nitric Oxide; Nitric Oxide Synthase; Phenylephrine; Pyrimidines; Rats; Rats, Wistar; Serotonin; Signal Transduction; Thromboxane A2; Vasoconstriction; Vasoconstrictor Agents

2017
Increased induction of inducible nitric oxide synthase expression in aortae of type 2 diabetes rats.
    Journal of pharmacological sciences, 2008, Volume: 107, Issue:2

    Topics: Animals; Aorta; Diabetes Mellitus, Type 2; Enzyme Induction; Interleukin-1beta; Lipopolysaccharides; Male; Nitric Oxide; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Wistar; Vasoconstriction

2008
Mechanisms underlying enhanced vasorelaxant response to protease-activated receptor 2-activating peptide in type 2 diabetic Goto-Kakizaki rat mesenteric artery.
    Peptides, 2009, Volume: 30, Issue:9

    Topics: Acetylcholine; Animals; Cyclooxygenase Inhibitors; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Endothelium, Vascular; Indomethacin; Male; Mesenteric Arteries; Nitrates; Nitric Oxide; Nitrites; Nitroarginine; Oligopeptides; Phenylephrine; Rats; Rats, Inbred Strains; Rats, Wistar; Receptor, PAR-2; Vasoconstriction; Vasodilation

2009
Baroreflex sensitivity predicts cardiovascular events in patients with type 2 diabetes mellitus without structural heart disease.
    Circulation journal : official journal of the Japanese Circulation Society, 2010, Volume: 74, Issue:7

    Topics: Aged; Baroreflex; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Heart Diseases; Humans; Incidence; Japan; Male; Middle Aged; Phenylephrine; Predictive Value of Tests

2010
Erectile dysfunction in young non-obese type II diabetic Goto-Kakizaki rats is associated with decreased eNOS phosphorylation at Ser1177.
    The journal of sexual medicine, 2010, Volume: 7, Issue:11

    Topics: Age Factors; AMP-Activated Protein Kinases; Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Male; Multienzyme Complexes; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Penile Erection; Penis; Phenylephrine; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Regression Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA; Vasoconstrictor Agents

2010
Vascular responses to 8-nitro-cyclic GMP in non-diabetic and diabetic mice.
    British journal of pharmacology, 2011, Volume: 162, Issue:8

    Topics: Animals; Aorta, Thoracic; Blotting, Western; Cyclic GMP; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Endothelium, Vascular; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type III; Obesity; Phenylephrine; Vasoconstriction; Vasodilation

2011
Preserved arterial vasodilatation via endothelial protease-activated receptor-2 in obese type 2 diabetic mice.
    British journal of pharmacology, 2011, Volume: 164, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholinesterase; Alcohol Oxidoreductases; Animals; Arteries; Blood Glucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Glucose; Glycosuria; Male; Mice; Mice, Inbred C57BL; Nitroprusside; Obesity; Oligopeptides; Phenylephrine; Potassium; Receptor, PAR-2; Receptors, Leptin; RNA, Messenger; Vasodilation

2011
Endothelin-mediated in vivo pressor responses following TRPV1 activation.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 301, Issue:3

    Topics: Adrenergic alpha-Agonists; Analysis of Variance; Animals; Azepines; Biphenyl Compounds; Blood Pressure; Capsaicin; Cells, Cultured; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Dipeptides; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Femoral Artery; Indoles; Infusions, Intravenous; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenylephrine; Receptor, Endothelin A; Receptor, Endothelin B; TRPV Cation Channels; Vasoconstriction; Vasoconstrictor Agents

2011
Aminoguanidine normalizes ET-1-induced aortic contraction in type 2 diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) rats by suppressing Jab1-mediated increase in ET(A)-receptor expression.
    Peptides, 2012, Volume: 33, Issue:1

    Topics: Acetylglucosamine; Animals; Aorta, Thoracic; Blood Glucose; Blood Pressure; COP9 Signalosome Complex; Diabetes Mellitus, Type 2; Dinoprostone; Endothelin-1; Endothelins; Extracellular Signal-Regulated MAP Kinases; Glycation End Products, Advanced; Guanidines; In Vitro Techniques; Insulin; Intracellular Signaling Peptides and Proteins; Male; Peptide Fragments; Phenylephrine; Phosphorylation; Proteins; Rats; Rats, Inbred OLETF; Receptor, Endothelin A; Receptor, Endothelin B; Vasoconstriction

2012
Simultaneous renal hypertension and type 2 diabetes exacerbate vascular endothelial dysfunction in rats.
    International journal of experimental pathology, 2012, Volume: 93, Issue:3

    Topics: Acetylcholine; Animals; Aorta; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Endothelium, Vascular; Glucose Tolerance Test; Hypertension, Renal; Male; Malondialdehyde; NG-Nitroarginine Methyl Ester; Nitroprusside; Phenylephrine; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents; Vasodilator Agents

2012
Angiotensin-receptor-blocker-induced refractory hypotension responds to methylene blue.
    Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:7

    Topics: Aged; Angiotensin Receptor Antagonists; Carbazoles; Carvedilol; Citalopram; Crystalloid Solutions; Diabetes Mellitus, Type 2; Drug Resistance; Female; Gastric Bypass; Humans; Hypotension; Isotonic Solutions; Obesity, Morbid; Phenylephrine; Preoperative Care; Propanolamines; Tetrazoles; Valine; Valsartan

2012
Suppressed G-protein-coupled receptor kinase 2 activity protects female diabetic-mouse aorta against endothelial dysfunction.
    Acta physiologica (Oxford, England), 2013, Volume: 207, Issue:1

    Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Aorta; Clonidine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; G-Protein-Coupled Receptor Kinase 2; Male; Mice; Mice, Inbred ICR; Nitric Oxide Synthase Type III; Phenylephrine; Proto-Oncogene Proteins c-akt; Sex Characteristics; Signal Transduction; Vasoconstriction; Vasoconstrictor Agents

2013
Gender difference in vascular and platelet reactivity to thromboxane A(2)-mimetic U46619 and to endothelial dependent vasodilation in Zucker fatty (hypertensive, hyperinsulinemic) diabetic rats.
    Diabetes research and clinical practice, 2003, Volume: 59, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin II; Animals; Blood Pressure; Diabetes Mellitus, Type 2; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Female; Kidney Cortex; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Platelet Aggregation; Rats; Rats, Zucker; Renal Circulation; Sex Characteristics; Vasoconstrictor Agents; Vasodilation

2003
Alterations in vascular endothelial function in the aorta and mesenteric artery in type II diabetic rats.
    Canadian journal of physiology and pharmacology, 2004, Volume: 82, Issue:3

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Biological Factors; Chlorides; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Hyperglycemia; Indomethacin; Insulin; Isotonic Solutions; Male; Mesenteric Artery, Superior; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nitric Oxide; Nitroarginine; Nitroprusside; Norepinephrine; Phenylephrine; Potassium; Rats; Rats, Wistar; Sodium

2004
A role for the alpha1-adrenergic signalling pathway in the response of papillary muscles from type 2 diabetic hearts to anoxia-reoxygenation.
    Cardiovascular drugs and therapy, 2004, Volume: 18, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Hypoxia; Male; Myocardial Contraction; Myocardium; Papillary Muscles; Phenylephrine; Prazosin; Rats; Rats, Zucker; Receptors, Adrenergic, alpha-1; Signal Transduction

2004
Compromised arterial function in human type 2 diabetic patients.
    Diabetes, 2005, Volume: 54, Issue:8

    Topics: Adult; Aged; Arteries; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Humans; Male; Mammary Arteries; Middle Aged; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroprusside; Phenylephrine; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Vasoconstriction

2005
Ocular and cardiovascular autonomic function in diabetic patients with varying severity of retinopathy.
    Indian journal of physiology and pharmacology, 2005, Volume: 49, Issue:2

    Topics: Adult; Autonomic Nervous System Diseases; Cardiovascular System; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Exercise; Eye; Hand Strength; Heart Rate; Humans; Middle Aged; Miotics; Mydriatics; Phenylephrine; Pilocarpine; Pupil; Respiration; Severity of Illness Index

2005
A nonthiazolidinedione peroxisome proliferator-activated receptor gamma agonist reverses endothelial dysfunction in diabetic (db/db-/-) mice.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 316, Issue:1

    Topics: Acetates; Adrenergic alpha-Agonists; Animals; Blood Glucose; Blotting, Western; Cholesterol; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Endothelium, Vascular; Hypoglycemic Agents; Indoles; Lipid Peroxidation; Male; Malondialdehyde; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase Type III; Phenylephrine; PPAR gamma; Receptors, Cell Surface; Receptors, Leptin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2006
Mitochondrial dysfunction as the cause of the failure to precondition the diabetic human myocardium.
    Cardiovascular research, 2006, Feb-01, Volume: 69, Issue:2

    Topics: Adenosine; Adrenergic alpha-Agonists; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diazoxide; Enzyme Activation; Glyburide; Heart Atria; Humans; Hypoglycemic Agents; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Membrane Potentials; Metformin; Mitochondria, Heart; Myocardial Ischemia; p38 Mitogen-Activated Protein Kinases; Phenylephrine; Potassium Channels; Protein Kinase C; Reactive Oxygen Species; Tetradecanoylphorbol Acetate

2006
Hypersensitivity of prediabetic JCR:LA-cp rats to fine airborne combustion particle-induced direct and noradrenergic-mediated vascular contraction.
    Toxicological sciences : an official journal of the Society of Toxicology, 2006, Volume: 90, Issue:2

    Topics: Air Pollutants; Animals; Aorta, Thoracic; Atherosclerosis; Carbon; Coal Ash; Diabetes Mellitus, Type 2; In Vitro Techniques; Insulin Resistance; Male; Particulate Matter; Phenylephrine; Rats; Rats, Inbred Strains; Vasoconstriction

2006
Myogenic tone and reactivity of rat ophthalmic artery in acute exposure to high glucose and in a type II diabetic model.
    Investigative ophthalmology & visual science, 2006, Volume: 47, Issue:2

    Topics: Angiography; Animals; Carbachol; Cytochrome P-450 Enzyme Inhibitors; Diabetes Mellitus, Type 2; Endothelium, Vascular; Glucose; Hyperglycemia; Male; Miconazole; Muscle Tonus; Muscle, Smooth, Vascular; Ophthalmic Artery; Ouabain; Phenylephrine; Rats; Rats, Inbred BB; Rats, Sprague-Dawley; Rats, Zucker; Sodium-Potassium-Exchanging ATPase; Vasoconstrictor Agents; Vasomotor System

2006
Pioglitazone mitigates renal glomerular vascular changes in high-fat, high-calorie-induced type 2 diabetes mellitus.
    American journal of physiology. Renal physiology, 2006, Volume: 291, Issue:3

    Topics: Animals; Arterioles; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dietary Fats; Hemodynamics; Homocysteine; Kidney Glomerulus; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Nitric Oxide; Oxidative Stress; Phenylephrine; Pioglitazone; Thiazolidinediones

2006
Alteration of vascular reactivity in diabetic human mammary artery and the effects of thiazolidinediones.
    The Journal of pharmacy and pharmacology, 2006, Volume: 58, Issue:12

    Topics: Aged; Cromakalim; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endothelium, Vascular; Female; Glyburide; Humans; Hypoglycemic Agents; Male; Mammary Arteries; Middle Aged; Nitroprusside; Phenylephrine; Pioglitazone; Potassium Channel Blockers; Potassium Chloride; Rosiglitazone; Thiazolidinediones; Vasoconstriction

2006
Altered role of smooth muscle endothelin receptors in coronary endothelin-1 and alpha1-adrenoceptor-mediated vasoconstriction in Type 2 diabetes.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:4

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Coronary Vessels; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Dietary Fats; Dose-Response Relationship, Drug; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Obesity; Oligopeptides; Peptides, Cyclic; Phenylephrine; Piperidines; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Adrenergic, alpha-1; Vasoconstriction

2007
Adenosine actions are preserved in corpus cavernosum from obese and type II diabetic db/db mouse.
    The journal of sexual medicine, 2008, Volume: 5, Issue:5

    Topics: Acetylcholine; Adenosine; Adenosine Kinase; Animals; Diabetes Mellitus, Type 2; Dipyridamole; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Male; Mice; Mice, Mutant Strains; Mice, Obese; Muscle Contraction; Muscle, Smooth; Nitroprusside; Penis; Phenylephrine; Phosphodiesterase Inhibitors; Tubercidin; Vasoconstrictor Agents; Vasodilator Agents

2008
Evidence of alpha1-adrenoceptor functional changes in omental arteries of patients with end-stage renal disease.
    Autonomic & autacoid pharmacology, 2008, Volume: 28, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Arteries; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Humans; Imines; Kidney Failure, Chronic; Male; Middle Aged; Omentum; Phenylephrine; Piperazines; Piperidines; Receptors, Adrenergic, alpha-1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vasoconstriction; Vasoconstrictor Agents

2008
Elevated epidermal growth factor receptor phosphorylation induces resistance artery dysfunction in diabetic db/db mice.
    Diabetes, 2008, Volume: 57, Issue:6

    Topics: Animals; Coronary Vessels; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Endothelium, Vascular; ErbB Receptors; Mesenteric Arteries; Mice; Nitric Oxide Synthase Type III; Phenylephrine; Phosphorylation

2008
Erectile dysfunction in the type II diabetic db/db mouse: impaired venoocclusion with altered cavernosal vasoreactivity and matrix.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:5

    Topics: Acetylcholine; Animals; Blood Glucose; Blood Pressure; Body Weight; Collagen; Desmosine; Diabetes Mellitus, Type 2; Disease Models, Animal; Elastin; Electric Stimulation; Erectile Dysfunction; Extracellular Matrix; Hydroxyproline; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Myography; Organ Size; Penis; Phenylephrine; Polymerase Chain Reaction; Receptors, Leptin; Regional Blood Flow; RNA, Messenger; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Veins

2008
Effects of streptozotocin-induced diabetes on vascular reactivity in genetically hyperinsulinaemic obese Zucker rats.
    Journal of cardiovascular pharmacology, 1996, Volume: 27, Issue:6

    Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; In Vitro Techniques; Insulin; Male; Mesentery; Obesity; Phenylephrine; Rats; Rats, Zucker; Serotonin; Serotonin Receptor Agonists; Streptozocin; Vasoconstriction

1996
[An unusual episode of angina].
    Minerva cardioangiologica, 1999, Volume: 47, Issue:3

    Topics: Aged; Angina Pectoris; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Electrocardiography; Female; Humans; Myocardial Ischemia; Ophthalmic Solutions; Phenylephrine; Pregnancy; Risk Factors; Vasoconstrictor Agents

1999
Sympathetic denervation of the iris dilator in noninsulin-dependent diabetes.
    Optometry and vision science : official publication of the American Academy of Optometry, 1991, Volume: 68, Issue:12

    Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Female; Glycated Hemoglobin; Humans; Iris; Male; Middle Aged; Nerve Degeneration; Phenylephrine; Random Allocation; Reflex, Pupillary; Tropicamide

1991