Page last updated: 2024-08-16

phenylephrine and Brain Ischemia

phenylephrine has been researched along with Brain Ischemia in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19904 (16.00)18.7374
1990's9 (36.00)18.2507
2000's9 (36.00)29.6817
2010's3 (12.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brown, RJ; Dhar, R; Grady, J; McCullough, LD; Roy, B; Wang, YB1
Harris, WB; LeSar, CJ; Sprouse, LR1
Cilio, C; Cronberg, T; Hansson, SR; Ley, D; Markus, T; Wieloch, T1
MISKO, JC1
Barker, PB; Beauchamp, NJ; Hillis, AE; Jacobs, MA; Ulatowski, JA; Wityk, RJ1
Chalela, JA; Dunn, B; Todd, JW; Warach, S1
Bukharovich, I; Hefer, D; Nasrallah, EJ; Plotnikov, A1
Wityk, RJ1
Bellolio, MF; Gilmore, RM; Porter, AB; Rabinstein, AA; Stead, LG1
Koizumi, K; Lazar, J; Orman, R; Saito, T; Sakamoto, K; Salciccioli, L; Stewart, M1
Ay, H; Ayata, C; Boas, DA; Jones, PB; Moskowitz, MA; Nishimura, M; Shin, HK1
D'Alecy, LG; Stirling, MS; Zelenock, GB1
Dacey, RG; Diringer, MN; Miller, JA1
Chi, OZ; Klein, SL; Tse, J; Wei, HM; Weiss, HR1
Ames, A; Crow, RJ; Kawamata, T; Maynard, KI; Ogilvy, CS; Smrcka, M1
Atarashi, H; Hayakawa, H; Nomura, A; Saitoh, H1
DeWitt, DS; Prough, DS1
Aiyagari, V; Cross , DT; Dacey , RG; Deibert, E; Diringer, MN1
Chen, F; Jiang, J; Pernow, J; Tokuno, S; Valen, G1
Kodama, K; Shibata, S; Tominaga, K; Ueki, S; Watanabe, S1
Grubb, RL; Modica, PA; Rich, KM; Tempelhoff, R1
Cole, DJ; Drummond, JC; Giamela, R; Patel, PM; Steinauer, J1
Cole, DJ; Drummond, JC; Matsumura, JS; Schultz, RL; Wong, MH1
Becker, DP; Muizelaar, JP1

Reviews

2 review(s) available for phenylephrine and Brain Ischemia

ArticleYear
Blood pressure augmentation in acute ischemic stroke.
    Journal of the neurological sciences, 2007, Oct-15, Volume: 261, Issue:1-2

    Topics: Acute Disease; Animals; Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Clinical Trials as Topic; Disease Models, Animal; Humans; Hypertension; Phenylephrine; Stroke

2007
Ameliorating cerebral hypoperfusion after traumatic brain injury.
    Critical care medicine, 1999, Volume: 27, Issue:11

    Topics: Animals; Arginine; Blood Flow Velocity; Blood Pressure; Brain Injuries; Brain Ischemia; Cerebral Cortex; Cerebrovascular Circulation; Humans; Hypotension; Phenylephrine; Prognosis; Vasoconstrictor Agents

1999

Trials

3 trial(s) available for phenylephrine and Brain Ischemia

ArticleYear
Perfusion-weighted MRI as a marker of response to treatment in acute and subacute stroke.
    Neuroradiology, 2004, Volume: 46, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Brain; Brain Ischemia; Cardiotonic Agents; Cognition Disorders; Endpoint Determination; Female; Fluid Therapy; Follow-Up Studies; Humans; Magnetic Resonance Angiography; Male; Middle Aged; Phenylephrine; Prognosis; Prospective Studies; Sensitivity and Specificity; Severity of Illness Index; Stroke; Treatment Outcome

2004
Safety of hypertensive hypervolemic therapy with phenylephrine in the treatment of delayed ischemic deficits after subarachnoid hemorrhage.
    Stroke, 1995, Volume: 26, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Blood Pressure; Blood Volume; Brain Ischemia; Cerebrovascular Circulation; Female; Hemodynamics; Humans; Male; Middle Aged; Phenylephrine; Plasma Substitutes; Subarachnoid Hemorrhage; Vasoconstrictor Agents

1995
Safety of hemodynamic augmentation in patients treated with Guglielmi detachable coils after acute aneurysmal subarachnoid hemorrhage.
    Stroke, 2001, Volume: 32, Issue:9

    Topics: Acute Disease; Adult; Blood Pressure; Blood Vessel Prosthesis; Blood Vessel Prosthesis Implantation; Brain Ischemia; Cardiac Output; Dobutamine; Dopamine; Female; Fluid Therapy; Glasgow Coma Scale; Heart Rate; Hemodynamics; Humans; Injections, Intravenous; Male; Middle Aged; Phenylephrine; Recurrence; Risk Assessment; Subarachnoid Hemorrhage; Treatment Outcome; Vasospasm, Intracranial

2001

Other Studies

20 other study(ies) available for phenylephrine and Brain Ischemia

ArticleYear
Comparison of Initial Vasopressors Used for Delayed Cerebral Ischemia after Aneurysmal Subarachnoid Hemorrhage.
    Cerebrovascular diseases (Basel, Switzerland), 2017, Volume: 43, Issue:5-6

    Topics: Adult; Aged; Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Disability Evaluation; Drug Substitution; Female; Humans; Male; Middle Aged; Norepinephrine; Phenylephrine; Retrospective Studies; Risk Factors; Subarachnoid Hemorrhage; Time Factors; Treatment Outcome; Vasoconstrictor Agents

2017
Permissive hypertension during awake eversion carotid endarterectomy: a physiologic approach for cerebral protection.
    Journal of the American College of Surgeons, 2014, Volume: 218, Issue:4

    Topics: Aged; Aged, 80 and over; Brain Ischemia; Carotid Artery, Common; Carotid Stenosis; Conscious Sedation; Endarterectomy, Carotid; Female; Follow-Up Studies; Humans; Hypertension; Intraoperative Complications; Male; Middle Aged; Phenylephrine; Retrospective Studies; Treatment Outcome; Vasoconstrictor Agents

2014
β-Adrenoceptor activation depresses brain inflammation and is neuroprotective in lipopolysaccharide-induced sensitization to oxygen-glucose deprivation in organotypic hippocampal slices.
    Journal of neuroinflammation, 2010, Dec-20, Volume: 7

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic beta-Agonists; Animals; Brain Ischemia; Cell Death; Cytokines; Dobutamine; Encephalitis; Glucose; Hippocampus; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Microglia; Neurons; Neuroprotective Agents; Oxygen; Phenylephrine; Receptors, Adrenergic, beta; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Terbutaline; Tissue Culture Techniques

2010
SELECTIVE CEREBRAL HYPOTHERMIA: PHYSIOLOGY AND TECHNIC.
    Annals of surgery, 1965, Volume: 161

    Topics: Blood; Brain; Brain Ischemia; Dogs; Electrocardiography; Hydrogen-Ion Concentration; Hypotension; Hypothermia; Hypothermia, Induced; Ischemic Attack, Transient; Lactates; Metabolism; Oximetry; Papaverine; Pharmacology; Phenylephrine; Research; Vasodilator Agents

1965
Induced hypertension improves cerebral blood flow in acute ischemic stroke.
    Neurology, 2005, Jun-14, Volume: 64, Issue:11

    Topics: Acute Disease; Aged; Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Humans; Hypertension; Infarction, Anterior Cerebral Artery; Injections, Intravenous; Magnetic Resonance Imaging; Male; Phenylephrine; Stroke; Treatment Outcome; Vasoconstrictor Agents

2005
Prominent positive U waves appearing with high-dose intravenous phenylephrine.
    Journal of electrocardiology, 2005, Volume: 38, Issue:4

    Topics: Aged; Antihypertensive Agents; Arrhythmias, Cardiac; Brain Ischemia; Electrocardiography; Female; Humans; Injections, Intravenous; Phenylephrine

2005
Pharmacologic elevation of blood pressure for acute brain ischemia.
    Neurocritical care, 2008, Volume: 8, Issue:2

    Topics: Acute Disease; Blood Pressure; Brain Ischemia; Carotid Stenosis; Cerebrovascular Circulation; Female; Humans; Middle Aged; Phenylephrine; Tomography, X-Ray Computed; Vasoconstrictor Agents

2008
Autonomic consequences of kainic acid-induced limbic cortical seizures in rats: peripheral autonomic nerve activity, acute cardiovascular changes, and death.
    Epilepsia, 2008, Volume: 49, Issue:6

    Topics: Animals; Autonomic Nervous System; Baroreflex; Blood Pressure; Brain Ischemia; Cardiac Output, Low; Cerebral Cortex; Echocardiography; Electrocardiography; Electroencephalography; Epilepsy; Excitatory Amino Acid Agonists; Heart; Heart Rate; Hypothalamus; Kainic Acid; Limbic System; Male; Medulla Oblongata; Nitroprusside; Peripheral Nerves; Phenylephrine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System

2008
Mild induced hypertension improves blood flow and oxygen metabolism in transient focal cerebral ischemia.
    Stroke, 2008, Volume: 39, Issue:5

    Topics: Animals; Brain Ischemia; Cerebrovascular Circulation; Disease Models, Animal; Energy Metabolism; Homeostasis; Hypertension; Infarction, Middle Cerebral Artery; Laser-Doppler Flowmetry; Mice; Oxygen Consumption; Oxyhemoglobins; Phenylephrine; Stroke; Treatment Outcome; Vasoconstrictor Agents

2008
Dissociation of the pressor and cerebral protective effects of phenylephrine.
    Archives of surgery (Chicago, Ill. : 1960), 1984, Volume: 119, Issue:4

    Topics: Animals; Brain Ischemia; Cerebrovascular Circulation; Cerebrovascular Disorders; Hypertension; Hypoxia, Brain; Male; Phenylephrine; Rats; Rats, Inbred Strains

1984
Cerebral microregional oxygen balance during chronic versus acute hypertension in middle cerebral artery occluded rats.
    Anesthesia and analgesia, 1996, Volume: 82, Issue:3

    Topics: Acute Disease; Adaptation, Physiological; Anesthesia, Inhalation; Animals; Autoradiography; Blood Pressure; Brain; Brain Ischemia; Cerebral Arteries; Cerebral Cortex; Cerebral Veins; Cerebrovascular Circulation; Cerebrovascular Disorders; Chronic Disease; Hypertension; Ischemic Attack, Transient; Microcirculation; Microspectrophotometry; Oxygen; Oxygen Consumption; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstrictor Agents

1996
Induced hypertension improves regional blood flow and protects against infarction during focal ischemia: time course of changes in blood flow measured by laser Doppler imaging.
    Neurosurgery, 1998, Volume: 42, Issue:3

    Topics: Animals; Blood Pressure; Brain Ischemia; Cerebral Infarction; Cerebrovascular Circulation; Laser-Doppler Flowmetry; Male; Phenylephrine; Rabbits; Time Factors; Ultrasonography; Vasoconstrictor Agents

1998
[Possible contribution of alpha-adrenergic abnormalities to cerebral ischemia in the patients with sinus bradycardia. Analysis by pharmacologic autonomic nervous test].
    Nihon Ika Daigaku zasshi, 1999, Volume: 66, Issue:2

    Topics: Adolescent; Adult; Aged; Arrhythmia, Sinus; Atropine; Autonomic Nervous System; Bradycardia; Brain Ischemia; Female; Humans; Male; Middle Aged; Parasympatholytics; Phentolamine; Phenylephrine; Propranolol; Receptors, Adrenergic, alpha; Sympatholytics; Sympathomimetics; Syncope; Vasoconstriction

1999
Effects of spontaneous or induced brain ischemia on vessel reactivity: the role of inducible nitric oxide synthase.
    Life sciences, 2002, Jun-28, Volume: 71, Issue:6

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Brain Ischemia; Dinoprost; Disease Models, Animal; In Vitro Techniques; Ischemic Attack, Transient; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardial Ischemia; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phenylephrine; Reference Values

2002
Assessment of the role of adrenoceptor function in ischemia-induced impairment of 2-deoxyglucose uptake and CA1 field potential in rat hippocampal slices.
    European journal of pharmacology, 1992, Oct-20, Volume: 221, Issue:2-3

    Topics: Action Potentials; Animals; Brain Ischemia; Deoxyglucose; Hippocampus; In Vitro Techniques; Male; Phenylephrine; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic

1992
Computerized electroencephalographic monitoring and selective shunting: influence on intraoperative administration of phenylephrine and myocardial infarction after general anesthesia for carotid endarterectomy.
    Neurosurgery, 1992, Volume: 30, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, General; Blood Pressure; Brain Ischemia; Carotid Stenosis; Cerebral Infarction; Cerebrovascular Circulation; Electroencephalography; Endarterectomy; Female; Humans; Intraoperative Complications; Male; Middle Aged; Monitoring, Intraoperative; Myocardial Infarction; Neurologic Examination; Phenylephrine; Risk Factors; Signal Processing, Computer-Assisted

1992
Delayed institution of hypertension during focal cerebral ischemia: effect on brain edema.
    Acta neuropathologica, 1991, Volume: 81, Issue:3

    Topics: Animals; Blood Pressure; Brain; Brain Edema; Brain Ischemia; Cerebral Arteries; Hemodynamics; Histocytochemistry; Hypertension; Phenylephrine; Rats; Rats, Inbred SHR; Staining and Labeling; Tetrazolium Salts

1991
Time- and pressure-dependent changes in blood-brain barrier permeability after temporary middle cerebral artery occlusion in rats.
    Acta neuropathologica, 1991, Volume: 82, Issue:4

    Topics: Animals; Arterial Occlusive Diseases; Blood Pressure; Blood-Brain Barrier; Brain; Brain Edema; Brain Ischemia; Cerebral Arteries; Evans Blue; Hydrogen-Ion Concentration; Hypertension; Lanthanum; Male; Permeability; Phenylephrine; Rats; Rats, Inbred SHR; Reperfusion

1991
Phenylephrine and myocardial ischemia in patients undergoing carotid endarterectomy.
    Anesthesiology, 1989, Volume: 71, Issue:3

    Topics: Brain Ischemia; Carotid Arteries; Coronary Disease; Endarterectomy; Humans; Intraoperative Complications; Phenylephrine

1989
Induced hypertension for the treatment of cerebral ischemia after subarachnoid hemorrhage. Direct effect on cerebral blood flow.
    Surgical neurology, 1986, Volume: 25, Issue:4

    Topics: Adult; Blood Pressure; Brain; Brain Ischemia; Cerebrovascular Circulation; Female; Humans; Hypertension; Middle Aged; Phenylephrine; Regional Blood Flow; Subarachnoid Hemorrhage; Xenon Radioisotopes

1986