phenylephrine has been researched along with Alloxan Diabetes in 178 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (12.92) | 18.7374 |
| 1990's | 50 (28.09) | 18.2507 |
| 2000's | 64 (35.96) | 29.6817 |
| 2010's | 36 (20.22) | 24.3611 |
| 2020's | 5 (2.81) | 2.80 |
| Authors | Studies |
|---|---|
| Abdelaziz, RR; Amin, FM; Nader, MA; Shehatou, GSG | 1 |
| Chakravarthi, S; Chellian, J; David, SR; Lai, PPN; Rajabalaya, R | 1 |
| Crespo, MJ; Morales, M; Ramírez, JM; Román, M | 1 |
| Chen, XY; Deng, CY; Kuang, SJ; Liu, L; Mai, LP; Rao, F; Wu, FL; Xue, YM; Yang, H; Yang, M; Zeng, Z; Zhang, L; Zhang, MZ; Zhou, MY | 1 |
| Leung, SWS; Mokhtar, SS; Rasool, AHG; Singh, KKB; Wee, CL; Yahaya, S | 1 |
| Bansal, S; Chopra, K | 1 |
| Hamaguchi, S; Kanae, H; Kato, K; Kusakabe, T; Namekata, I; Tanaka, H; Wakasugi, Y | 1 |
| Kasono, K; Nobe, K; Ohtake, K; Takenouchi, Y | 1 |
| Chaudhary, P; Schreihofer, AM | 1 |
| Ai, J; Cai, BZ; Chen, QX; Liu, J; Sun, LH; Wang, N; Xie, F; Yang, BF; Ye, JH | 1 |
| Kamalinejad, M; Kharazmi, F; Sohrabipour, S; Soltani, N | 1 |
| Fassot, C; Guihot, AL; Henrion, D; Loufrani, L; Maquigneau, M; Toutain, B; Vessières, E | 1 |
| Hao, ZS; He, HM; Lu, HG; Ren, LM; Zhao, D; Zhuo, YJ | 1 |
| Anderson, L; Han, X; Rahimian, R; Zhang, R | 1 |
| Kawamura, R; Kobayashi, T; Matsumoto, T; Taguchi, K; Watanabe, S | 1 |
| Al-Noah, Z; Burgard, E; Kullmann, FA; Langdale, C; Marson, L; McKenna, D; Thor, KB | 1 |
| Chennupati, R; De Mey, JG; Janssen, BJ; Köhler, SE; Lamers, WH; Marion, V; Meens, MJ | 1 |
| Benham, C; Dugic, E; Lione, L; Mackenzie, LS; Rehman, AU | 1 |
| Bobadilla-Lugo, RA; Bracho-Valdés, I; Ibarra-Barajas, M; Tufiño, C; Villanueva-López, C | 1 |
| Kongyingyoes, B; Kukongviriyapan, U; Pannangpetch, P; Semaming, Y; Thukhammee, W | 1 |
| Leung, SW; Mokhtar, SS; Rasool, AH; Suppian, R; Vanhoutte, PM; Yusof, MI | 1 |
| Anderson, L; Han, X; Rahimian, R; Shaligram, S; Zhang, R | 1 |
| Alahdal, AM; Azhar, A; Banjar, ZM; El-Bassossy, HM; Elberry, AA; Ghareib, SA; Watson, ML | 1 |
| da Silva, CH; de Oliveira, AM; do Prado, AF; Gomes, MS; Moreira, JD; Moreira, RP; Pernomian, L | 1 |
| Addepalli, V; Bhatt, LK; Parkar, NA | 1 |
| Botelho, T; de Batista, PR; Padilha, AS; Ribeiro-Júnior, RF; Simões, FV; Vassallo, DV | 1 |
| Lione, LA; Mackenzie, LS; Oweis, N; Perez-Diaz, N; Pushkarsky, I | 1 |
| Abdullah, NA; Johns, EJ; Khan, MA; Lazahari, MI; Sattar, MA | 1 |
| Chang, CK; Cheng, JT; Cheng, KC; Juang, SW; Kou, DH; Liu, IM; Tong, YC | 1 |
| Chen, L; Han, B; Lai, Y; Ni, G; Wang, K; Wang, L; Xu, B; Yu, L; Yu, X; Zhou, S; Zhu, Q | 1 |
| Gurney, AM; Howarth, FC | 1 |
| Abboud, K; Bassila, JC; Ghali-Ghoul, R; Sabra, R | 1 |
| Demirkazik, A; Emre, M; Kavak, S; Meral, I; Pelit, A; Unlugenc, H | 1 |
| Abdulla, MH; Abdullah, NA; Basri, F; Dewa, A; Hussain, NM; Johns, EJ; Kazi, RN; Khan, MA; Rathore, HA; Salman, IM; Sattar, MA; Swarup, KR | 1 |
| Cheng, ZJ; Harden, SW; Li, L; Lin, M; Wurster, RD | 1 |
| Arellano-Mendoza, MG; Castorena-Torres, F; Coronel, I; del Valle-Mondragon, L; Escalante, B; Rios, A; Romo, E; Vargas-Robles, H | 1 |
| Johnson, CD; Kizub, IV; Pavlova, OO; Soloviev, AI; Zholos, AV | 1 |
| Cameron, NE; Cotter, MA; Nangle, MR | 3 |
| Caldwell, RB; Caldwell, RW; Toque, HA; Tostes, RC; Webb, RC; Xu, Z; Yao, L | 1 |
| Béraud, G; Boulanger, E; Bulckaen, H; Creusy, C; Fontaine, P; Gaxatte, C; Prévost, G; Puisieux, F | 1 |
| Ai, J; Lu, GY; Qiao, GF; Sun, C; Sun, LH; Wang, LH; Wang, N; Yang, BF; Zhang, R | 1 |
| Petrović, N; Radenković, M; Roganović, J; Stojić, D; Tanić, N | 1 |
| Chang, XW; Li, S; Shan, JL; Sun, P; Tang, WB; Wang, PS; Xie, DP; Yang, TT; Zhao, T; Zhou, YQ | 1 |
| Blanco, S; Croci, T; Ferazzini, M; Grasso, M; Guagnini, F | 1 |
| Kamata, K; Kobayashi, T; Matsumoto, T; Taguchi, K | 1 |
| Campos, OA; Hall, KE; McDonald, MW; Melling, CW; Murias, JM; Noble, EG | 1 |
| Hu, J; Li, H; Li, YL; Li, ZL; Qiu, PC; Wang, SW; Yang, Q; Zhou, XX | 1 |
| Abo-Warda, SM; El-Bassossy, HM; Fahmy, A | 1 |
| Albornoz, LE; Cardinali, DP; Damiano, PF; Linares, LM; Reyes-Toso, CF; Rosón, MI | 1 |
| Cameron, NE; Cotter, MA; Jack, AM; Keegan, A | 1 |
| Angelini, GD; Jeremy, JY; Mikhailidis, DP; Shukla, N; Thompson, CS | 1 |
| Bruckdorfer, KR; Dashwood, MR; Mikhailidis, DP; Morgan, RJ; Mumtaz, FH; Naseem, KM; Sullivan, ME; Thompson, CS | 1 |
| Cameron, NE; Cotter, MA; Inkster, ME | 1 |
| Davel, AP; Rossoni, LV; Vassallo, DV; Xavier, FE | 1 |
| Bezuijen, MW; Levendusky, MC; Longhurst, PA | 1 |
| Baluchnejadmojarad, T; Roghani, M | 1 |
| Aberle, NS; Anversa, P; Kajstura, J; Norby, FL; Ren, J | 1 |
| Akin, FB; Ozansoy, G | 1 |
| Ahn, GJ; Choi, SM; Kang, KK; Kim, WB; Kwon, JW | 1 |
| Cellek, S; Kalsi, JS; Kell, PD; Madge, DJ; Ralph, DJ | 1 |
| Bounelis, P; Chatham, JC; Marchase, RB; Pang, Y | 1 |
| Kamata, K; Kobayashi, T; Matsumoto, T; Wakabayashi, K | 1 |
| Baluchnejadmojarad, T; Imani, A; Roghani, M | 1 |
| Arán, M; Cardinali, DP; Linares, LM; Pinto, JE; Reyes-Toso, CF; Ricci, CR; Rodríguez, RR | 1 |
| Abdullah, NA; Armenia, A; Helmi, A; Johns, EJ; Munavvar, AS | 1 |
| Bianchi, L; Colivicchi, MA; Della Corte, L; Pirisino, R; Raimondi, L; Tipton, KF | 1 |
| Ayanğolu-Dülger, G; Paskaloglu, K; Sener, G | 1 |
| Amour, J; Coriat, P; David, JS; Riou, B; Vivien, B | 1 |
| Carvalho Leone, AF; Coelho, EB | 1 |
| Aloyo, V; Raffa, RB; Schulingkamp, RJ; Tallarida, RJ | 1 |
| Balaraman, R; Majithiya, JB; Paramar, AN | 1 |
| Alp, NJ; Cai, S; Channon, KM; Khoo, J; Mussa, S | 1 |
| Babül, A; Dileköz, E; Ercan, ZS; Gülen, S; Ozer, C | 1 |
| Balaraman, R; Majithiya, JB | 1 |
| Achike, FI; Ajay, M; Mustafa, AM; Mustafa, MR | 1 |
| Fathollahi, Y; Hajizadeh, S; Shiran, K | 1 |
| Farrokhfall, K; Fatehi, M; Fatehi-Hassanabad, Z; Imen-Shahidi, M; Parsaeei, H | 1 |
| Falcone, JC; Fleming, JT; Joshua, IG; Passmore, JC; Rodriguez, WE; Tyagi, N; Tyagi, SC | 1 |
| D'Agord Schaan, B; da Silva Soares, PP; da Silva, VO; Dall'ago, P; de Angelis, K; Irigoyen, MC; Werner, J | 1 |
| Goseki, T; Ishikawa, H; Mashimo, K; Nishimoto, H; Shimizu, K; Uga, S; Yoshitomi, T | 1 |
| Drábiková, K; Jancinová, V; Nosál', R; Nosál'ová, V; Okruhlicová, L; Sotníková, R; Zúrová-Nedelcevová, J | 1 |
| Bernátová, I; Drábiková, K; Jancinová, V; Kristová, V; Navarová, J; Nosál'ová, V; Petríková, M; Snirc, V; Sotníková, R; Zúrová-Nedelcevová, J | 1 |
| De Angelis, K; Irigoyen, M; Maeda, C; Oliveira, E; Oliveira, V; Schaan, B | 1 |
| Bender, SB; Klabunde, RE | 1 |
| Araki, M; Fukuda, M; Hirabara, Y; Honda, K; Katafuchi, S; Saito, R; Takano, Y | 1 |
| Dolber, PC; Fraser, MO; Yang, Z | 1 |
| Ari, N; Aşan, E; Bali, M; Ceylan-Isik, A; Hünkar, T; Karasu, C; Kaymaz, F; Renda, N; Soncul, H; Söylemezoğlu, T | 1 |
| Chen, X; Guan, Y; Liu, J; Ma, L; Ren, J; Zhu, B | 1 |
| Chen, HY; Chen, JJ; Cheng, JT; Wu, JS | 1 |
| Abebe, W | 1 |
| Abdullah, NA; Johns, EJ; Khan, MA; Sattar, MA | 1 |
| Belmadani, S; Boulares, HA; Gonzalez-Villalobos, RA; Matrougui, K; Palen, DI | 1 |
| Abdullah, NA; Armenia, A; Johns, EJ; Khan, MA; Sattar, MA | 1 |
| Carrier, GO; Scarborough, NL | 1 |
| Dudley, P; Pfaffman, MA; Prater, A | 1 |
| Fletcher, HP; Sandage, BW | 1 |
| Darby, A; Hilman, R; Pfaffman, MA | 1 |
| Ball, CR; Darby, A; Hilman, R; Pfaffman, MA | 1 |
| Cohen, RA; Tesfamariam, B | 1 |
| Graves, JE; Poston, L; Taylor, PD | 1 |
| Austin, CE; Chess-Williams, R; Otter, DJ | 1 |
| Cohen, RA; Palacino, JJ; Tesfamariam, B; Weisbrod, RM | 1 |
| Amos, G; Brown, L; Miller, B | 1 |
| Chess-Williams, R; Otter, DJ | 1 |
| Marubashi, S; Saito, K; Sasaki, H; Sato, N; Takahashi, K; Wakasugi, K; Yamatani, K | 1 |
| Murray, P; Pitt, B; Webb, RC | 1 |
| Christ, GJ; Gondré, MC; Valcic, M | 1 |
| Biessels, GJ; De Wildt, DJ; Erkelens, DW; Gispen, WH; Kappelle, AC; Van Buren, T | 1 |
| Gando, S; Hattori, Y; Kanno, M | 1 |
| Akaishi, T; Homma, S | 1 |
| Fernandes, TG; Irigoyen, MC; Lulhier, F; Maeda, CY | 1 |
| Archibald, V; Cameron, NE; Cotter, MA; Keegan, A | 1 |
| Distant, DA; Dresner, LS; Fleishhacker, JF; Mueller, CM; Wait, RB; Wang, SP; West, MW | 1 |
| Turner, NC; White, P | 1 |
| Cameron, NE; Cotter, MA; Keegan, A; Walbank, H | 1 |
| Alder, VA; Cringle, SJ; Su, EN; Yu, DY; Yu, PK | 1 |
| Irlbeck, M; Zimmer, HG | 1 |
| De Wildt, DJ; Gispen, WH; Kappelle, AC; Kasbergen, CM; Van Buren, T | 1 |
| Itoh, T; Masuda, Y; Michijiri, S; Murai, S; Nakamura, K; Saito, H | 1 |
| Böttcher, U; Eblenkamp, M; Fischer, Y; Jüngling, E; Kammermeier, H; Rösen, P; Thomas, J | 1 |
| Dewhurst, M; Stevens, EJ; Tomlinson, DR | 1 |
| Tomlinson, DR; Vo, PA | 1 |
| Dresner, LS; Mueller, CM; Ponomarenko, IN; Wait, RB; Wang, SP; West, MW | 1 |
| Cohen, RA; Griswold, MC; Pagano, PJ; Ravel, D | 1 |
| Clough, RW; Kienast, SG; Steger, RW | 1 |
| De Wildt, DJ; Gispen, WH; Kasbergen, CM; Van Buren, T | 1 |
| Cameron, NE; Cotter, MA; Keegan, A | 2 |
| Mulay, S; Omer, S; Shan, J; Varma, DR | 1 |
| Karasu, C | 2 |
| Elías, MM; García, VM; Ochoa, JE | 1 |
| Guan, YY; He, H; Lin, MJ; Zhu, BH | 1 |
| Bouchard, JF; Dumont, EC; Lamontagne, D | 1 |
| Dalsgaard, GT; Johansen, T; Nyborg, NC; Sheykhzade, M | 1 |
| Elghozi, JL; Laude, D; Mésangeau, D | 1 |
| Davel, AP; Rossoni, LV; Vassallo, DV | 1 |
| Alper, G; Cinar, MG; Evinç, A; Ulker, S | 1 |
| Birowo, P; Kamil, ST; Shahab, N; Taher, A | 1 |
| Cakici, I; Karasu , C; Zobali, F | 1 |
| Cameron, NE; Cotter, MA; Jack, AM | 1 |
| Gouty, S; Helke, CJ; Regalia, J | 1 |
| Guan, YY; He, H; Min, J; Zhu, BH | 1 |
| Austin, CE; Chess-Williams, R | 1 |
| Miyagawa, I; Nakamura, I; Takahashi, C | 1 |
| Azadzoi, KM; Saenz de Tejada, I | 1 |
| McGiff, JC; Quilley, J; Sarubbi, D | 1 |
| Chang, KS; Stevens, WC | 1 |
| Buczek-Thomas, JA; Jaspers, SR; Miller, TB | 1 |
| Lavoie, L; van de Werve, G | 1 |
| Mitchell, JR; Saggerson, ED | 1 |
| Davison, JS; Mantle, M; Mathison, R; Thakore, E | 1 |
| Ingbar, SH; Kubota, K | 1 |
| Mayhan, WG | 1 |
| McGiff, JC; Quilley, J | 1 |
| Gispen, WH; Van den Buuse, M; Van der Zee, CE | 1 |
| Longhurst, PA | 1 |
| Carrara, MC | 1 |
| Agrawal, DK; McNeill, JH | 1 |
| Kamata, K; Kasuya, Y; Miyata, N | 1 |
| Chang, KS; Tanz, RD; Weller, TS | 1 |
| Legan, E | 1 |
| Gebremedhin, D; Hadházy, P; Koltai, MZ; Magyar, K; Pogátsa, G | 1 |
| Belis, JA; Brotcke, TP; Burrell, CL; Longhurst, PA | 1 |
| Carrier, GO; White, RE | 2 |
| Gøtzsche, O | 1 |
| Jackson, CV; McGrath, GM; McNeill, JH | 1 |
| Ballagi-Pordány, G; Hadházy, P; Koltai, MZ; Köszeghy, A; Pogátsa, G | 1 |
| Durante, W; Sen, AK; Sunahara, FA | 1 |
| Akagi, Y; Kador, PF; Kinoshita, JH; Terubayashi, H | 1 |
| Silva, P; Spokes, K; Williams, ME | 1 |
| Gebremedhin, D; Hadházy, P; Koltai, MZ; Pogátsa, G | 1 |
| Gerald, MC; Kolta, MG; Wallace, LJ | 1 |
| Gulbenkian, A; Tabachnick, II | 1 |
| Cseuz, R; Kunos, G; Szentiványi, M; Wenger, TL | 1 |
178 other study(ies) available for phenylephrine and Alloxan Diabetes
| Article | Year |
|---|---|
Piperine mitigates aortic vasculopathy in streptozotocin-diabetic rats via targeting TXNIP-NLRP3 signaling.
Topics: Acetylcholine; Animals; Aorta; Cell Cycle Proteins; Diabetes Mellitus, Experimental; Inflammasomes; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Phenylephrine; Rats; Rats, Sprague-Dawley; Streptozocin; Vascular Diseases | 2023 |
Influence of rutin and its combination with metformin on vascular functions in type 1 diabetes.
Topics: Acetylcholine; Animals; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Endothelium, Vascular; Lipids; Male; Metformin; Phenylephrine; Rats; Rats, Sprague-Dawley; Rutin | 2023 |
Significant reduction of vascular reactivity with dantrolene and nimodipine in diabetic rats: a potential approach to cerebral vasospasm management in diabetes.
Topics: Acetylcholine; Animals; Dantrolene; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Endothelium, Vascular; Male; Nimodipine; Phenylephrine; Rats; Rats, Sprague-Dawley; Vasodilator Agents; Vasospasm, Intracranial | 2020 |
Abnormal Ca
Topics: Animals; Aorta; Biomarkers; Calcium; Calcium Channels; Calcium Signaling; Diabetes Mellitus, Experimental; Gene Knockdown Techniques; Inhibitory Concentration 50; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phenotype; Phenylephrine; Rats, Zucker; Stromal Interaction Molecule 1; Vasoconstriction; Vasodilation | 2020 |
Calcitriol Supplementation Ameliorates Microvascular Endothelial Dysfunction in Vitamin D-Deficient Diabetic Rats by Upregulating the Vascular eNOS Protein Expression and Reducing Oxidative Stress.
Topics: Animals; Calcitriol; Diabetes Mellitus, Experimental; Dietary Supplements; Endothelium, Vascular; Male; Malondialdehyde; Mesenteric Arteries; Microvessels; Nitric Oxide Synthase Type III; Nitroprusside; Oxidative Stress; Phenylephrine; Rats, Sprague-Dawley; Superoxide Dismutase; Up-Regulation; Vasoconstriction; Vasodilation; Vitamin D Deficiency | 2021 |
Selective ER-α agonist alleviates vascular endothelial dysfunction in ovariectomized type 2 diabetic rats.
Topics: Acetylcholine; Animals; Aorta; Biomarkers; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endothelium, Vascular; Estradiol; Estrogen Receptor alpha; Female; Glyburide; Inflammation; Lipids; Nitric Oxide Synthase Type III; Nitriles; Nitroprusside; Organ Size; Ovariectomy; Oxidative Stress; Phenols; Phenylephrine; Propionates; Pyrazoles; Rats, Sprague-Dawley; Uterus | 2018 |
Pathological prolongation of action potential duration as a cause of the reduced alpha-adrenoceptor-mediated negative inotropy in streptozotocin-induced diabetic mice myocardium.
Topics: 4-Aminopyridine; Action Potentials; Animals; Cromakalim; Depression, Chemical; Diabetes Mellitus, Experimental; Male; Mice, Inbred Strains; Myocardial Contraction; Phenylephrine; Receptors, Adrenergic, alpha; Streptozocin | 2017 |
Eicosapentaenoic acid ethyl ester improves endothelial dysfunction in type 2 diabetic mice.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Glucose; Cardiovascular Agents; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Eicosapentaenoic Acid; Endothelium, Vascular; Insulin; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle Contraction; Nitroprusside; Phenylephrine; Tissue Culture Techniques; Vasodilation | 2018 |
Improved glucose homeostasis in male obese Zucker rats coincides with enhanced baroreflexes and activation of the nucleus tractus solitarius.
Topics: Animals; Baroreflex; Blood Glucose; Blood Pressure; Bradycardia; Diabetes Mellitus, Experimental; Heart Rate; Homeostasis; Hypertension; Male; Obesity; Phenylephrine; Rats, Zucker; Solitary Nucleus | 2018 |
Blockage of peripheral NPY Y1 and Y2 receptors modulates barorefex sensitivity of diabetic rats.
Topics: Animals; Arginine; Baroreflex; Benzazepines; Blood Pressure; Cholesterol; Cholesterol, LDL; Diabetes Mellitus, Experimental; Heart Rate; Hyperlipidemias; Male; Neuropeptide Y; Nitroprusside; Phenylephrine; Rats; Rats, Wistar; Receptors, Neuropeptide Y; Triglycerides | 2013 |
Effect of the administration of Solanum nigrum fruit on blood glucose, lipid profiles, and sensitivity of the vascular mesenteric bed to phenylephrine in streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Calcium; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Fruit; Glucose Tolerance Test; Lipids; Magnesium; Male; Mesentery; Perfusion; Phenylephrine; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Solanum nigrum | 2013 |
COX-2-derived prostanoids and oxidative stress additionally reduce endothelium-mediated relaxation in old type 2 diabetic rats.
Topics: Acetylcholine; Animals; Blood Glucose; Blood Pressure; Body Weight; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endothelium, Vascular; Male; Oxidative Stress; Phenylephrine; Prostaglandins; Rats; Reactive Oxygen Species; Vasoconstriction; Vasodilation | 2013 |
Berberine improves neurogenic contractile response of bladder detrusor muscle in streptozotocin-induced diabetic rats.
Topics: Adenosine Triphosphate; Animals; Berberine; Carbachol; Diabetes Mellitus, Experimental; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Phenylephrine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Urinary Bladder | 2013 |
Sexual dimorphism in rat aortic endothelial function of streptozotocin-induced diabetes: possible involvement of superoxide and nitric oxide production.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Diabetes Mellitus, Experimental; Endothelium, Vascular; Female; In Vitro Techniques; Male; Metalloporphyrins; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Phenylephrine; Rats; Rats, Sprague-Dawley; Sex Characteristics; Superoxides; Vasodilator Agents | 2014 |
Epigallocatechin gallate attenuates ET-1-induced contraction in carotid artery from type 2 diabetic OLETF rat at chronic stage of disease.
Topics: Acetylcholine; Animals; Carotid Arteries; Catechin; Chronic Disease; Diabetes Mellitus, Experimental; Endothelin-1; In Vitro Techniques; Male; NADPH Oxidases; Nitric Oxide Synthase Type III; Nitroprusside; Phenylephrine; Rats, Inbred OLETF; Receptors, Endothelin; Superoxide Dismutase; Vasoconstriction; Vasodilation | 2014 |
Nitrergic relaxations and phenylephrine contractions are not compromised in isolated urethra in a rat model of diabetes.
Topics: Animals; Diabetes Mellitus, Experimental; Electric Stimulation; Enzyme Inhibitors; Female; Immunohistochemistry; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Nitroprusside; Phenylephrine; Rats, Sprague-Dawley; Sympathomimetics; Urethra | 2014 |
Endothelial arginine resynthesis contributes to the maintenance of vasomotor function in male diabetic mice.
Topics: Acetylcholine; Animals; Arginase; Arginine; Argininosuccinate Synthase; Blood Pressure; Citrulline; Diabetes Mellitus, Experimental; Endothelial Cells; Endothelium; Female; Heart Rate; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Phenylephrine; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Vasomotor System | 2014 |
Selective inhibition of NADPH oxidase reverses the over contraction of diabetic rat aorta.
Topics: Animals; Aorta; Benzoxazoles; Diabetes Mellitus, Experimental; Male; NADPH Oxidases; Phenylephrine; Rats; Rats, Wistar; Triazoles; Vasoconstriction | 2014 |
Experimental gestational diabetes mellitus induces blunted vasoconstriction and functional changes in the rat aorta.
Topics: Angiotensin II; Animals; Diabetes Mellitus, Experimental; Diabetes, Gestational; Female; Humans; Losartan; Phenylephrine; Pregnancy; Rats; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2014 |
Protocatechuic Acid Restores Vascular Responses in Rats With Chronic Diabetes Induced by Streptozotocin.
Topics: Animals; Antioxidants; Blood Glucose; Blood Pressure; Catalase; Diabetes Mellitus, Experimental; Heart Rate; Hydroxybenzoates; Insulin; Male; Malondialdehyde; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Phenylephrine; Rats; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase | 2016 |
Reduced nitric oxide-mediated relaxation and endothelial nitric oxide synthase expression in the tail arteries of streptozotocin-induced diabetic rats.
Topics: Animals; Arteries; Blood Glucose; Body Weight; Cyclic AMP; Cyclic GMP; Diabetes Mellitus, Experimental; Endothelium, Vascular; Epoprostenol; Gene Expression Regulation, Enzymologic; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase Type III; Phenylephrine; Potassium Chloride; Rats; Receptors, Epoprostenol; Tail; Vasodilation | 2016 |
Sex-specific vascular responses of the rat aorta: effects of moderate term (intermediate stage) streptozotocin-induced diabetes.
Topics: Acetylcholine; Animals; Aorta; Aorta, Thoracic; Diabetes Mellitus, Experimental; Endothelium, Vascular; Female; Male; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phenylephrine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Streptozocin; Vasodilation; Vasodilator Agents | 2016 |
Protective effect of zingerone on increased vascular contractility in diabetic rat aorta.
Topics: Animals; Aorta; Diabetes Mellitus, Experimental; Glycation End Products, Advanced; Guaiacol; Male; Phenylephrine; Rats; Rats, Wistar; Vasoconstriction; Vasodilation; Vasodilator Agents | 2016 |
Enhanced nitric oxide generation from nitric oxide synthases as the cause of increased peroxynitrite formation during acute restraint stress: Effects on carotid responsiveness to angiotensinergic stimuli in type-1 diabetic rats.
Topics: Angiotensin II; Animals; Behavior, Animal; Carotid Arteries; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Endothelial Cells; Enzyme Activation; Gene Expression Regulation, Enzymologic; Male; Nitric Oxide; Nitric Oxide Synthase; Peroxynitrous Acid; Phenylephrine; Phosphorylation; Rats; Rats, Wistar; Restraint, Physical; Stress, Psychological; Vasoconstriction | 2016 |
Efficacy of nobiletin, a citrus flavonoid, in the treatment of the cardiovascular dysfunction of diabetes in rats.
Topics: Acetylcholine; Animals; Antioxidants; Biomarkers; Cardiomegaly; Citrus; Diabetes Mellitus, Experimental; Flavones; Flavonoids; Hemodynamics; Hyperglycemia; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Oxidative Stress; Phenylephrine; Rats; Rats, Wistar | 2016 |
Treatment with high dose of atorvastatin reduces vascular injury in diabetic rats.
Topics: Animals; Aorta; Atorvastatin; Cyclooxygenase 2; Diabetes Mellitus, Experimental; Endothelium, Vascular; Indomethacin; Male; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitrobenzenes; Phenylephrine; Prostaglandins; Rats; Rats, Wistar; Streptozocin; Sulfonamides; Superoxides; Vascular System Injuries; Vasodilation; Vasodilator Agents | 2016 |
The Non-Genomic Effects of the PPARβγ Agonist GW0742 on Streptozotocin Treated Rat Aorta.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta; Diabetes Mellitus, Experimental; Genome; Male; Myocardial Contraction; Phenylephrine; PPAR gamma; PPAR-beta; Protein Kinase Inhibitors; Rats, Wistar; rho-Associated Kinases; Streptozocin; Thiazoles; Vasodilation | 2018 |
Clonidine and a novel clonidine analog AL-12 cause sympathoinhibition in spontaneously hypertensive and diabetic spontaneously hypertensive rats.
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Methoxamine; Neural Inhibition; Norepinephrine; Phenylephrine; Rats; Rats, Inbred SHR; Streptozocin | 2008 |
Role of hyperglycaemia in the pathogenesis of hypotension observed in type-1 diabetic rats.
Topics: Animals; Arecoline; Baroreflex; Cell Line; Cholinergic Agonists; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Gene Expression; Glucose; Hyperglycemia; Hypotension; Insulin; Male; Phenylephrine; Phlorhizin; Rats; Rats, Wistar; Receptor, Muscarinic M2; RNA, Messenger | 2008 |
Mechanisms of alpha1-adrenoceptor mediated QT prolongation in the diabetic rat heart.
Topics: Action Potentials; Animals; Diabetes Mellitus, Experimental; Electrocardiography; Male; Phenylephrine; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; RNA, Messenger; Streptozocin | 2009 |
Effects of streptozotocin-induced diabetes on the pharmacology of rat conduit and resistance intrapulmonary arteries.
Topics: Animals; Calcium Signaling; Carbachol; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Dinoprost; Endothelium, Vascular; Hypertension, Pulmonary; Male; Membrane Potentials; Muscle, Smooth, Vascular; Nitroglycerin; Phenylephrine; Potassium; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Wistar; Serotonin; Streptozocin; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents | 2009 |
Temporal changes in vascular reactivity in early diabetes mellitus in rats: role of changes in endothelial factors and in phosphodiesterase activity.
Topics: Acetylcholine; Allopurinol; Animals; Aorta, Thoracic; Blood Glucose; Cyclic Nucleotide Phosphodiesterases, Type 1; Cyclic Nucleotide Phosphodiesterases, Type 2; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclic Nucleotide Phosphodiesterases, Type 5; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Endothelium, Vascular; Female; Nitric Oxide Donors; Phenylephrine; Phosphoric Diester Hydrolases; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2009 |
Repetitive 50 Hz pulsed electromagnetic field ameliorates the diabetes-induced impairments in the relaxation response of rat thoracic aorta rings.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Body Weight; Diabetes Mellitus, Experimental; Electromagnetic Fields; In Vitro Techniques; Male; Nitroarginine; Nitroprusside; Phenylephrine; Rats; Rats, Wistar; Streptozocin; Vasodilation | 2009 |
Functional subtypes of renal alpha1-adrenoceptor in spontaneously hypertensive rats with streptozotocin-induced experimental diabetic nephropathy.
Topics: Adrenergic Antagonists; Amlodipine; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Electric Stimulation; Hypertension; Kidney; Male; Methoxamine; Norepinephrine; Phenylephrine; Rats; Rats, Inbred SHR; Receptors, Adrenergic, alpha-1; Streptozocin; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2009 |
Impairment of baroreflex control of heart rate in conscious transgenic mice of type 1 diabetes (OVE26).
Topics: Animals; Baroreflex; Blood Pressure; Bradycardia; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Heart; Heart Rate; Male; Mice; Mice, Transgenic; Nitroprusside; Phenylephrine; Tachycardia; Vasoconstrictor Agents; Vasodilator Agents; Wakefulness | 2010 |
L-arginine and antioxidant diet supplementation partially restores nitric oxide-dependent regulation of phenylephrine renal vasoconstriction in diabetics rats.
Topics: Animals; Antioxidants; Arginine; Ascorbic Acid; Biopterins; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dietary Supplements; Docosahexaenoic Acids; Eicosapentaenoic Acid; Enzyme Inhibitors; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phenylephrine; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxides; Vasoconstriction; Vasoconstrictor Agents; Vitamin E | 2010 |
Rho kinase and protein kinase C involvement in vascular smooth muscle myofilament calcium sensitization in arteries from diabetic rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arteries; Benzophenanthridines; Calcium; Diabetes Mellitus, Experimental; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Protein Kinase C; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Streptozocin | 2010 |
Poly(ADP-ribose) polymerase inhibition reverses nitrergic neurovascular dysfunctions in penile erectile tissue from streptozotocin-diabetic mice.
Topics: Acetylcholine; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Impotence, Vasculogenic; Male; Mice; Nitroprusside; Organic Chemicals; Oxidative Stress; Penile Erection; Penis; Phenylephrine; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases | 2010 |
Arginase II deletion increases corpora cavernosa relaxation in diabetic mice.
Topics: Acetylcholine; Animals; Arginase; Blood Glucose; Blotting, Western; Diabetes Mellitus, Experimental; Male; Mice; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type I; Nitroprusside; Penis; Phenylephrine; Vasodilation; Vasodilator Agents | 2011 |
Structural modifications in the arterial wall during physiological aging and as a result of diabetes mellitus in a mouse model: are the changes comparable?
Topics: Acetylcholine; Aging; Animals; Aorta; Arteries; Diabetes Mellitus, Experimental; Endothelium, Vascular; Male; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Receptor for Advanced Glycation End Products; Receptors, Immunologic | 2011 |
Protective effect of the daming capsule on impaired baroreflexes in STZ-induced diabetic rats with hyperlipoidemia.
Topics: Animals; Baroreflex; Blood Pressure; Brain; Cassia; Diabetes Mellitus, Experimental; Dietary Fats; Drugs, Chinese Herbal; Endoplasmic Reticulum; Heart Rate; Hyperlipidemias; Hypertension; Male; Mitochondria; Myelin Sheath; Nitroprusside; Panax; Phenylephrine; Phytotherapy; Pressoreceptors; Random Allocation; Rats; Rats, Wistar; Receptors, AMPA; Receptors, GABA-A; Rheum; RNA, Messenger; Salvia miltiorrhiza | 2010 |
Impairment of acetylcholine-mediated endothelium-dependent relaxation in isolated parotid artery of the alloxan-induced diabetic rabbit.
Topics: Acetylcholine; Alloxan; Animals; Arteries; Bradykinin; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Endothelium, Vascular; Enzyme Inhibitors; Female; Indomethacin; Isometric Contraction; Isothiuronium; Male; Muscarinic Antagonists; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroarginine; Nitroprusside; Parotid Gland; Phenylephrine; Potassium; Rabbits; Random Allocation; Receptor, Muscarinic M3; Vasoconstrictor Agents; Vasodilation | 2011 |
Effect of interleukin-6 (IL-6) on the vascular smooth muscle contraction in abdominal aorta of rats with streptozotocin-induced diabetes.
Topics: Animals; Aorta, Abdominal; Diabetes Mellitus, Experimental; Interleukin-6; Male; Muscle, Smooth, Vascular; Phenylephrine; Rats; Rats, Wistar; Streptozocin; Vasoconstriction | 2011 |
Erectile properties of the Rho-kinase inhibitor SAR407899 in diabetic animals and human isolated corpora cavernosa.
Topics: Administration, Oral; Animals; Diabetes Mellitus, Experimental; Humans; In Vitro Techniques; Injections, Intravenous; Isometric Contraction; Male; Muscle Relaxation; Penile Erection; Penis; Phenylephrine; Piperazines; Protein Kinase Inhibitors; Purines; Rabbits; Rats; rho-Associated Kinases; Sildenafil Citrate; Sulfones | 2012 |
Suppressed G-protein-coupled receptor kinase 2 activity protects female diabetic-mouse aorta against endothelial dysfunction.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Aorta; Clonidine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; G-Protein-Coupled Receptor Kinase 2; Male; Mice; Mice, Inbred ICR; Nitric Oxide Synthase Type III; Phenylephrine; Proto-Oncogene Proteins c-akt; Sex Characteristics; Signal Transduction; Vasoconstriction; Vasoconstrictor Agents | 2013 |
Vessel-specific rate of vasorelaxation is slower in diabetic rats.
Topics: Acetylcholine; Animals; Aorta; Arteries; Ascorbic Acid; Case-Control Studies; Diabetes Mellitus, Experimental; Femoral Artery; Iliac Artery; Male; Muscle, Smooth, Vascular; Myography; Nonlinear Dynamics; Phenylephrine; Rats; Rats, Sprague-Dawley; Regression Analysis; Time Factors; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Vitamins | 2013 |
Chronic supplementation of paeonol combined with danshensu for the improvement of vascular reactivity in the cerebral basilar artery of diabetic rats.
Topics: Acetophenones; Acetylcholine; Animals; Blood Glucose; Body Weight; Calcium Channels; Cerebral Arteries; Diabetes Mellitus, Experimental; Dietary Supplements; Dose-Response Relationship, Drug; Drug Therapy, Combination; Lactates; Male; Oxidative Stress; Phenylephrine; Potassium Channels; Rats; Superoxide Dismutase | 2012 |
Chrysin and luteolin attenuate diabetes-induced impairment in endothelial-dependent relaxation: effect on lipid profile, AGEs and NO generation.
Topics: Acetylcholine; Animals; Aorta; Blood Pressure; Cholesterol; Diabetes Mellitus, Experimental; Endothelium, Vascular; Flavonoids; Glycation End Products, Advanced; Luteolin; Male; Nitric Oxide; Phenylephrine; Rats; Rats, Wistar; Streptozocin; Triglycerides; Vasodilation | 2013 |
Vascular reactivity in diabetic rats: effect of melatonin.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Aorta; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Male; Melatonin; Muscle Relaxation; Phenylephrine; Rats; Rats, Wistar; Serotonin; Vasoconstriction | 2002 |
Effects of diabetes and evening primrose oil treatment on responses of aorta, corpus cavernosum and mesenteric vasculature in rats.
Topics: Animals; Antineoplastic Agents; Aorta, Thoracic; Biological Factors; Blood Glucose; Cannabinoid Receptor Modulators; Diabetes Mellitus, Experimental; Fatty Acids, Essential; gamma-Linolenic Acid; In Vitro Techniques; Linoleic Acids; Male; Muscle Contraction; Muscle, Smooth, Vascular; Oenothera biennis; Penis; Phenylephrine; Plant Oils; Rats; Splanchnic Circulation; Vasoconstrictor Agents | 2002 |
Homocysteine enhances impairment of endothelium-dependent relaxation and guanosine cyclic monophosphate formation in aortae from diabetic rabbits.
Topics: Acetylcholine; Animals; Aorta; Cyclic GMP; Diabetes Mellitus, Experimental; Endothelium, Vascular; Homocysteine; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitroprusside; Phenylephrine; Rabbits; Reference Values; Vasodilation | 2002 |
Enhanced relaxation of diabetic rabbit cavernosal smooth muscle in response to nitric oxide: potential relevance to erectile dysfunction.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Autoradiography; Binding Sites; Blood Glucose; Body Weight; Cholesterol; Diabetes Mellitus, Experimental; Electric Stimulation; Erectile Dysfunction; Histocytochemistry; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Penis; Phenylephrine; Rabbits; Vasodilator Agents | 2002 |
Effects of trientine, a metal chelator, on defective endothelium-dependent relaxation in the mesenteric vasculature of diabetic rats.
Topics: Acetylcholine; Animals; Biological Factors; Chelating Agents; Diabetes Mellitus, Experimental; Endothelium, Vascular; Enzyme Inhibitors; Male; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Phenylephrine; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Trientine; Vasoconstrictor Agents; Vasodilation | 2002 |
Time-dependent hyperreactivity to phenylephrine in aorta from untreated diabetic rats: role of prostanoids and calcium mobilization.
Topics: Animals; Aorta, Thoracic; Calcium; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Phenylephrine; Prostaglandins; Rats; Rats, Wistar; Time Factors; Vasoconstriction | 2003 |
Functional response of bladder strips from streptozotocin diabetic rats depends on bladder mass.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Diabetes Mellitus, Experimental; Electric Stimulation; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Norepinephrine; Organ Size; Phenylephrine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Urinary Bladder | 2003 |
Garlic extract attenuates time-dependent changes in the reactivity of isolated aorta in streptozotocin-diabetic rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Garlic; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Organ Culture Techniques; Phenylephrine; Plant Extracts; Rats; Rats, Sprague-Dawley; Streptozocin; Vasoconstriction; Vasodilation | 2003 |
Transgenic overexpression of insulin-like growth factor I prevents streptozotocin-induced cardiac contractile dysfunction and beta-adrenergic response in ventricular myocytes.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Angiotensin II; Animals; Body Weight; Calcium; Cells, Cultured; Diabetes Mellitus, Experimental; Gene Expression; Heart Ventricles; Insulin-Like Growth Factor I; Isoproterenol; Male; Mice; Mice, Inbred Strains; Mice, Transgenic; Models, Animal; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Organ Size; Phenylephrine | 2004 |
Effects of gemfibrozil treatment on vascular reactivity of streptozotocin-diabetic rat aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Glucose; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Experimental; Endothelium, Vascular; Gemfibrozil; Lipid Peroxidation; Male; Muscle, Smooth, Vascular; Phenylephrine; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Time Factors; Triglycerides; Vasoconstriction; Vasodilation | 2004 |
The effect of DA-8159 on corpus cavernosal smooth muscle relaxation and penile erection in diabetic rabbits.
Topics: Animals; Area Under Curve; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Male; Muscle Relaxation; Muscle, Smooth; Nitroprusside; Penile Erection; Penis; Phenylephrine; Phosphodiesterase Inhibitors; Pyrimidines; Rabbits; Sulfonamides; Vasoconstrictor Agents; Vasodilator Agents | 2004 |
A comparative study of sildenafil, NCX-911 and BAY41-2272 on the anococcygeus muscle of diabetic rats.
Topics: Adrenergic alpha-Agonists; Anal Canal; Animals; Diabetes Mellitus, Experimental; Electric Stimulation; Male; Muscle Relaxation; Muscles; Nitrergic Neurons; Phenylephrine; Phosphodiesterase Inhibitors; Piperazines; Purines; Pyrazoles; Pyridines; Rats; Rats, Wistar; Sacrococcygeal Region; Sildenafil Citrate; Sulfones | 2004 |
Hexosamine pathway is responsible for inhibition by diabetes of phenylephrine-induced inotropy.
Topics: Animals; Calcium; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Endoplasmic Reticulum; Glucosamine; Heart Rate; Hexosamines; Imidazoles; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Male; Myocardial Contraction; Phenylephrine; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum; Type C Phospholipases; Ventricular Function, Left | 2004 |
Alterations in vascular endothelial function in the aorta and mesenteric artery in type II diabetic rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Biological Factors; Chlorides; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Hyperglycemia; Indomethacin; Insulin; Isotonic Solutions; Male; Mesenteric Artery, Superior; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nitric Oxide; Nitroarginine; Nitroprusside; Norepinephrine; Phenylephrine; Potassium; Rats; Rats, Wistar; Sodium | 2004 |
Protective effect of enalapril on vascular reactivity of the rat aorta.
Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enalapril; Endothelium, Vascular; In Vitro Techniques; Isosorbide Dinitrate; Male; Muscle, Smooth, Vascular; Phenylephrine; Rats; Rats, Wistar; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2004 |
Effect of melatonin on vascular reactivity in pancreatectomized rats.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Aorta; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Endothelium, Vascular; Glucose; Glucose Tolerance Test; Laparotomy; Male; Melatonin; Muscle Relaxation; Pancreatectomy; Phenylephrine; Rats; Rats, Wistar; Vasoconstriction; Vasodilator Agents | 2004 |
The contribution of adrenoceptor subtype(s) in the renal vasculature of diabetic spontaneously hypertensive rats.
Topics: Animals; Blood Glucose; Clonidine; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Electric Stimulation; Infusions, Intravenous; Injections, Intraperitoneal; Injections, Intravenous; Kidney; Kidney Cortex; Malaysia; Male; Methoxamine; Muscle, Smooth, Vascular; Nitrendipine; Norepinephrine; Phenylephrine; Piperazines; Rats; Rats, Inbred SHR; Receptors, Adrenergic, alpha-1; Streptozocin; Time Factors; Vasoconstriction | 2004 |
Taurine prevents streptozotocin impairment of hormone-stimulated glucose uptake in rat adipocytes.
Topics: Adipocytes; Adrenergic Agonists; Adrenergic Antagonists; Animals; Deoxyglucose; Diabetes Mellitus, Experimental; Insulin; Isoproterenol; Male; Phenylephrine; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Taurine | 2004 |
Melatonin treatment protects against diabetes-induced functional and biochemical changes in rat aorta and corpus cavernosum.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glutathione; In Vitro Techniques; Insulin; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Muscle Contraction; Muscle Relaxation; Nitroprusside; Papaverine; Penis; Phenylephrine; Rats; Rats, Wistar; Time Factors; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2004 |
Interaction of halogenated anesthetics with alpha- and beta-adrenoceptor stimulations in diabetic rat myocardium.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Algorithms; Anesthetics, Inhalation; Animals; Diabetes Mellitus, Experimental; Drug Interactions; Halothane; Heart; Hydrocarbons, Halogenated; Isoflurane; Isoproterenol; Male; Methyl Ethers; Myocardial Contraction; Myocardium; Papillary Muscles; Phenylephrine; Rats; Sarcoplasmic Reticulum; Sevoflurane | 2004 |
Effects of prostanoids on phenylephrine-induced contractions in the mesenteric vascular bed of rats with streptozotocin-induced diabetes mellitus.
Topics: Adrenergic alpha-Agonists; Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Indomethacin; Male; Muscle, Smooth, Vascular; Perfusion; Phenylephrine; Prostaglandin Antagonists; Prostaglandins; Rats; Rats, Wistar; Splanchnic Circulation; Vasoconstriction | 2004 |
Changes in aorta alpha1-adrenoceptor number and affinity during one year of streptozotocin-induced diabetes in rats.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Animals; Aorta, Thoracic; Binding Sites; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; In Vitro Techniques; Isometric Contraction; Male; Muscle, Smooth, Vascular; Phenylephrine; Prazosin; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Streptozocin; Time Factors | 2005 |
Pioglitazone, a PPARgamma agonist, restores endothelial function in aorta of streptozotocin-induced diabetic rats.
Topics: Acetylcholine; Animals; Aorta; Blood Pressure; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Phenylephrine; Pioglitazone; PPAR gamma; Random Allocation; Rats; Rats, Sprague-Dawley; Thiazolidinediones; Vasoconstrictor Agents; Vasodilator Agents | 2005 |
Endothelial nitric oxide synthase dysfunction in diabetic mice: importance of tetrahydrobiopterin in eNOS dimerisation.
Topics: Acetylcholine; Animals; Biopterins; Diabetes Mellitus, Experimental; Dimerization; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nitroprusside; Phenylephrine; Reference Values; Superoxides | 2005 |
The effect of systemic leptin administration on aorta smooth muscle responses in diabetic rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Diabetes Mellitus, Experimental; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; In Vitro Techniques; Leptin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Phenylephrine; Rats; Rats, Wistar; Vasoconstrictor Agents; Vasodilator Agents | 2006 |
Metformin reduces blood pressure and restores endothelial function in aorta of streptozotocin-induced diabetic rats.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Aorta, Thoracic; Blood Pressure; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Combinations; Endothelium, Vascular; Hypoglycemic Agents; In Vitro Techniques; Lipid Peroxidation; Male; Metformin; NG-Nitroarginine Methyl Ester; Oxidative Stress; Phenylephrine; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Recovery of Function; Tetraethylammonium; Vasoconstriction; Vasodilation | 2006 |
Effect of quercetin on altered vascular reactivity in aortas isolated from streptozotocin-induced diabetic rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Diabetes Mellitus, Experimental; In Vitro Techniques; Male; Muscle Relaxation; Nitroprusside; Phenylephrine; Quercetin; Rats; Rats, Inbred WKY | 2006 |
Responsiveness of vascular alpha1-adrenoceptors of diabetic rat knee joint to phenylephrine in acute inflammation.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arthritis; Diabetes Mellitus, Experimental; Injections, Intra-Arterial; Joints; Male; Phenylephrine; Prazosin; Rats; Receptors, Adrenergic, alpha-1; Regional Blood Flow; Vasoconstriction | 2005 |
The beneficial in vitro effects of lovastatin and chelerythrine on relaxatory response to acetylcholine in the perfused mesentric bed isolated from diabetic rats.
Topics: Acetylcholine; Alkaloids; Animals; Benzophenanthridines; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Lovastatin; Male; Mesenteric Arteries; Nitroprusside; Perfusion; Phenanthridines; Phenylephrine; Protein Kinase C; Rats; Rats, Wistar; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2006 |
Pioglitazone mitigates renal glomerular vascular changes in high-fat, high-calorie-induced type 2 diabetes mellitus.
Topics: Animals; Arterioles; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dietary Fats; Hemodynamics; Homocysteine; Kidney Glomerulus; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Nitric Oxide; Oxidative Stress; Phenylephrine; Pioglitazone; Thiazolidinediones | 2006 |
The calpain inhibitor, A-705253, corrects penile nitrergic nerve dysfunction in diabetic mice.
Topics: Acetylcholine; Animals; Benzamides; Blood Glucose; Body Weight; Calpain; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Electric Stimulation; Male; Mice; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrergic Neurons; Nitroprusside; Organ Size; Penis; Phenylephrine; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2006 |
IkappaB kinase 2 inhibition corrects defective nitrergic erectile mechanisms in diabetic mouse corpus cavernosum.
Topics: Animals; Atropine; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Electric Stimulation; Guanethidine; I-kappa B Kinase; In Vitro Techniques; Male; Mice; Mice, Mutant Strains; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; NF-kappa B; Nitric Oxide Donors; Nitroprusside; Penile Erection; Penis; Phenylephrine; Vasoconstrictor Agents; Vasodilator Agents | 2006 |
Parasympathetic dysfunction is associated with baroreflex and chemoreflex impairment in streptozotocin-induced diabetes in rats.
Topics: Adrenergic alpha-Agonists; Animals; Autonomic Nervous System Diseases; Baroreflex; Binding, Competitive; Blood Pressure; Chemoreceptor Cells; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart Rate; Male; Methacholine Chloride; Muscarinic Antagonists; N-Methylscopolamine; Nitroprusside; Parasympathomimetics; Phenylephrine; Potassium Cyanide; Rats; Rats, Wistar; Receptors, Muscarinic; Tritium; Vagus Nerve; Vasodilator Agents | 2007 |
Pharmacological vascular reactivity in isolated diabetic rabbit ciliary artery.
Topics: Animals; Carbachol; Ciliary Arteries; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Dose-Response Relationship, Drug; Isotonic Solutions; Microscopy, Electron; Phenylephrine; Potassium; Rabbits; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2006 |
Ischaemia/reperfusion-induced organ injury in low dose streptozotocin diabetes.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Dose-Response Relationship, Drug; Intestinal Diseases; Intestine, Small; Male; Mesenteric Artery, Superior; Phenylephrine; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Streptozocin; Vasodilation | 2006 |
Participation of reactive oxygen species in diabetes-induced endothelial dysfunction.
Topics: Acetylcholine; Animals; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Hyperglycemia; Male; Phenylephrine; Rats; Rats, Wistar; Reactive Oxygen Species; Streptozocin; Vascular Diseases; Vasoconstrictor Agents; Vasodilation | 2006 |
Chronic salt loading and cardiovascular-associated changes in experimental diabetes in rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Arginine Vasopressin; Baroreflex; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Experimental; Ganglionic Blockers; Heart Rate; Hematocrit; Hexamethonium; Hormone Antagonists; Hypertension; Kidney; Losartan; Male; Nitroprusside; Organ Size; Peptidyl-Dipeptidase A; Phenylephrine; Rats; Rats, Wistar; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary; Sympathetic Nervous System; Vasoconstrictor Agents; Vasodilator Agents; Vasopressins | 2007 |
Altered role of smooth muscle endothelin receptors in coronary endothelin-1 and alpha1-adrenoceptor-mediated vasoconstriction in Type 2 diabetes.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Coronary Vessels; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Dietary Fats; Dose-Response Relationship, Drug; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Obesity; Oligopeptides; Peptides, Cyclic; Phenylephrine; Piperidines; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Adrenergic, alpha-1; Vasoconstriction | 2007 |
A high-sodium diet in streptozotocin-induced diabetic rats impairs endothelium-derived hyperpolarizing factor-mediated vasodilation.
Topics: Acetylcholine; Animals; Biological Factors; Blood Pressure; Diabetes Mellitus, Experimental; Heart Rate; Male; Mesenteric Arteries; Phenylephrine; Rats; Rats, Wistar; Sodium, Dietary; Streptozocin; Vasodilation | 2007 |
Diabetic urethropathy compounds the effects of diabetic cystopathy.
Topics: Adrenergic alpha-Agonists; Animals; Antibiotics, Antineoplastic; Arginine; Bungarotoxins; Diabetes Mellitus, Experimental; Electromyography; Female; Follow-Up Studies; Muscle Contraction; Phenylephrine; Rats; Rats, Sprague-Dawley; Streptozocin; Urethra; Urethral Diseases; Urinary Bladder; Urinary Bladder Diseases | 2007 |
Cod liver oil supplementation improves cardiovascular and metabolic abnormalities in streptozotocin diabetic rats.
Topics: Acetylcholine; Animals; Aorta; Blood Glucose; Cardiovascular Diseases; Cod Liver Oil; Diabetes Mellitus, Experimental; Dietary Supplements; Dose-Response Relationship, Drug; Endothelium, Vascular; Heart; Hydroxyproline; In Vitro Techniques; Isoproterenol; Lipids; Male; Metabolic Diseases; Microscopy, Electron; Myocardium; Nitroprusside; Norepinephrine; Phenylephrine; Rats; Rats, Wistar; Streptozocin; Vasoconstriction | 2007 |
Abnormalities of sarcoplasmic reticulum Ca2+ mobilization in aortic smooth muscle cells from streptozotocin-induced diabetic rats.
Topics: Animals; Aorta; Calcium; Calcium Signaling; Diabetes Mellitus, Experimental; Hyperglycemia; Indoles; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Myocytes, Smooth Muscle; Phenylephrine; Rats; Rats, Wistar; Ryanodine; Sarcoplasmic Reticulum | 2008 |
Impaired regulation function in cardiovascular neurons of nucleus tractus solitarii in streptozotocin-induced diabetic rats.
Topics: Action Potentials; Animals; Baroreflex; Blood Pressure; Cardiotonic Agents; Cardiovascular System; Diabetes Mellitus, Experimental; Disease Models, Animal; Electrocardiography; Electrodes; Heart Rate; Male; Neurons; Phenylephrine; Rats; Rats, Wistar; Solitary Nucleus | 2008 |
Effects of taurine on the reactivity of aortas from diabetic rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Calcium; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Combinations; Glucose; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Protein Kinase C; Rats; Rats, Inbred WKY; Taurine | 2008 |
Alpha1A- and alpha1D-adrenoceptors are the major functional subtypes of renal alpha1-adrenoceptors in streptozotocin-induced diabetic and normal Sprague-Dawley rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Electric Stimulation; Kidney; Male; Methoxamine; Nitrendipine; Norepinephrine; Phenylephrine; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Renal Artery; Renal Circulation; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2008 |
Elevated epidermal growth factor receptor phosphorylation induces resistance artery dysfunction in diabetic db/db mice.
Topics: Animals; Coronary Vessels; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Endothelium, Vascular; ErbB Receptors; Mesenteric Arteries; Mice; Nitric Oxide Synthase Type III; Phenylephrine; Phosphorylation | 2008 |
Functional subtypes of renal alpha1-adrenoceptor in diabetic and non-diabetic 2K1C Goldblatt renovascular hypertension.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Animals; Clonidine; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Electric Stimulation; Hypertension, Renovascular; Kidney; Male; Methoxamine; Nitrendipine; Norepinephrine; Phenylephrine; Piperazines; Rats; Rats, Sprague-Dawley; Vasoconstriction | 2008 |
Increased alpha 2-adrenoreceptor mediated vascular contraction in diabetic rats.
Topics: Adrenergic alpha-Agonists; Animals; Aorta; Calcium; Clonidine; Diabetes Mellitus, Experimental; In Vitro Techniques; Male; Norepinephrine; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasoconstriction | 1983 |
Relationship between untreated and insulin-treated diabetes and vascular relaxation.
Topics: Animals; Aorta; Blood Glucose; Diabetes Mellitus, Experimental; In Vitro Techniques; Insulin; Male; Muscle, Smooth, Vascular; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred Strains; Streptozocin; Theophylline; Vasoconstriction; Vasodilation | 1983 |
Glycemic response to selected sympathomimetics in stressed normal and goldthioglucose mice.
Topics: Animals; Aurothioglucose; Blood Glucose; Corticosterone; Diabetes Mellitus; Diabetes Mellitus, Experimental; Ephedrine; Male; Mice; Obesity; Phenylephrine; Phenylpropanolamine; Stress, Physiological; Sympathomimetics | 1983 |
Contractile and relaxing activity of arterial smooth muscle from streptozotocin-diabetic rats.
Topics: Animals; Aorta; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Insulin; Male; Muscle, Smooth, Vascular; Phenylephrine; Rats; Theophylline; Vasoconstriction; Vasodilation | 1980 |
Insulin reversal of diabetes-induced inhibition of vascular contractility in the rat.
Topics: Animals; Aorta; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Insulin; Kinetics; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Rats; Rats, Inbred Strains | 1982 |
Enhanced adrenergic neurotransmission in diabetic rabbit carotid artery.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Carotid Arteries; Cocaine; Diabetes Mellitus, Experimental; Electric Stimulation; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Rabbits; Sympathetic Nervous System; Vasoconstriction | 1995 |
Selective impairment of acetylcholine-mediated endothelium-dependent relaxation in isolated resistance arteries of the streptozotocin-induced diabetic rat.
Topics: Acetylcholine; Animals; Bradykinin; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Endothelium, Vascular; Hindlimb; Male; Mesenteric Arteries; Nitric Oxide; Phenylephrine; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Vasoconstriction; Vasodilation | 1995 |
Influence of adrenoceptor stimulation on aggregation of platelets from diabetic and control rats.
Topics: Adenosine Diphosphate; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Aorta, Thoracic; Blood Glucose; Diabetes Mellitus, Experimental; Epinephrine; Heart; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Platelet Aggregation; Rats; Rats, Wistar | 1995 |
Aldose reductase inhibition restores endothelial cell function in diabetic rabbit aorta.
Topics: Acetylcholine; Adenosine Diphosphate; Aldehyde Reductase; Animals; Aorta; Blood Glucose; Body Weight; Cyclic GMP; Diabetes Mellitus, Experimental; Endothelium, Vascular; Imidazoles; Imidazolidines; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Prostaglandins; Rabbits; Sorbitol | 1993 |
Disease-induced changes in alpha-adrenoceptor-mediated cardiac and vascular responses in rats.
Topics: Animals; Cardiovascular System; Diabetes Mellitus, Experimental; Disease Models, Animal; Hemodynamics; Hypertension; Hyperthyroidism; Hypothyroidism; In Vitro Techniques; Male; Methimazole; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Wistar; Receptors, Adrenergic, alpha-1; Triiodothyronine | 1994 |
The effects of aldose reductase inhibition with ponalrestat on changes in vascular function in streptozotocin diabetic rats.
Topics: Aldehyde Reductase; Animals; Aorta, Thoracic; Carbachol; Colforsin; Diabetes Mellitus, Experimental; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Phenylephrine; Phthalazines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 1994 |
Catecholamine-induced cAMP response in streptozotocin-induced diabetic rat liver.
Topics: Adipose Tissue; Animals; Colforsin; Cyclic AMP; Diabetes Mellitus, Experimental; Emaciation; Epinephrine; Glucagon; Glucose; Insulin; Isoproterenol; Lactates; Lactic Acid; Liver; Male; Oxymetazoline; Phenylephrine; Propranolol; Pyruvates; Pyruvic Acid; Rats; Receptors, Adrenergic, beta; Streptozocin | 1994 |
Ramipril prevents hypersensitivity to phenylephrine in aorta from streptozotocin-induced diabetic rats.
Topics: Acetylcholine; Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Endothelium, Vascular; Male; Muscle, Smooth, Vascular; Phenylephrine; Ramipril; Rats; Rats, Inbred WKY; Streptozocin; Vasoconstriction; Vasodilation | 1994 |
Augmentation in the kinetic characteristics of phenylephrine- and 5-hydroxytryptamine-induced contractions in the isolated rat aorta following eight weeks of STZ-diabetes.
Topics: Animals; Aorta; Diabetes Mellitus, Experimental; Drug Interactions; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Rats; Rats, Inbred F344; Reference Values; Serotonin; Time Factors | 1994 |
Effects of nimodipine on sciatic nerve blood flow and vasa nervorum responsiveness in the diabetic rat.
Topics: Analysis of Variance; Animals; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Laser-Doppler Flowmetry; Male; Nimodipine; Phenylephrine; Rats; Rats, Wistar; Regional Blood Flow; Sciatic Nerve; Vasa Nervorum | 1993 |
Altered cardiac adrenergic neurotransmission in streptozotocin-induced diabetic rats.
Topics: Animals; Atropine; Catecholamines; Diabetes Mellitus, Experimental; Electric Stimulation; Heart; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Neuroeffector Junction; Norepinephrine; Phenylephrine; Rats; Rats, Wistar; Sympathetic Nervous System; Synaptic Transmission; Tyramine; Yohimbine | 1993 |
Baroreceptor control of vasopressin-producing cells in streptozotocin diabetic rats.
Topics: Action Potentials; Animals; Arginine Vasopressin; Diabetes Mellitus, Experimental; Male; Neurons; Nitroprusside; Phenylephrine; Pressoreceptors; Rats; Rats, Wistar; Supraoptic Nucleus | 1993 |
Streptozotocin diabetes modifies arterial pressure and baroreflex sensitivity in rats.
Topics: Animals; Baroreflex; Blood Glucose; Blood Pressure; Cardiotonic Agents; Diabetes Mellitus, Experimental; Heart Rate; Insulin; Male; Phenylephrine; Rats; Rats, Wistar; Renin | 1995 |
Contraction and relaxation of aortas from diabetic rats: effects of chronic anti-oxidant and aminoguanidine treatments.
Topics: Acetylcholine; Acetylcysteine; Analysis of Variance; Animals; Antioxidants; Aorta; Butylated Hydroxytoluene; Diabetes Mellitus, Experimental; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Guanidines; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Phenylephrine; Rats; Rats, Sprague-Dawley | 1996 |
Effects of diabetes and uremia on mesenteric vascular reactivity.
Topics: Acetylcholine; Animals; Body Weight; Diabetes Mellitus, Experimental; Endothelium, Vascular; Hyperglycemia; Male; Mesenteric Arteries; Microcirculation; Muscle, Smooth, Vascular; Nephrectomy; Nitroprusside; Organ Size; Phenylephrine; Rats; Rats, Sprague-Dawley; Streptozocin; Uremia; Vasoconstrictor Agents; Vasodilation | 1996 |
Effects of streptozotocin-induced diabetes on vascular reactivity in genetically hyperinsulinaemic obese Zucker rats.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; In Vitro Techniques; Insulin; Male; Mesentery; Obesity; Phenylephrine; Rats; Rats, Zucker; Serotonin; Serotonin Receptor Agonists; Streptozocin; Vasoconstriction | 1996 |
Chronic vitamin E treatment prevents defective endothelium-dependent relaxation in diabetic rat aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Endothelium, Vascular; Free Radical Scavengers; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; Phenylephrine; Rats; Rats, Sprague-Dawley; Vitamin E | 1995 |
Altered vasoactivity in the early diabetic eye: measured in the isolated perfused rat eye.
Topics: Angiotensin II; Animals; Catecholamines; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Dinoprost; Eye; Isoproterenol; Male; Optic Nerve; Phenylephrine; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Serotonin; Vascular Resistance; Vasoconstrictor Agents | 1995 |
Functional responses of the left and right heart of diabetic rats to alpha- and beta-adrenergic receptor stimulation.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Analysis of Variance; Animals; Blood Pressure; Cardiotonic Agents; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Female; Heart Rate; Isoproterenol; Phenylephrine; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Ventricular Function, Left; Ventricular Function, Right | 1996 |
A disturbed macrocirculatory supply as a determinant for a reduced sciatic nerve blood flow in diabetic rats.
Topics: Adrenergic alpha-Agonists; Adrenocorticotropic Hormone; Animals; Blood Pressure; Diabetes Mellitus, Experimental; Male; Microcirculation; Peptide Fragments; Phenylephrine; Rats; Rats, Wistar; Regional Blood Flow; Sciatic Nerve; Tyramine | 1996 |
Effects of short-term (2 weeks) streptozotocin-induced diabetes on acetylcholine and noradrenaline in the salivary glands and secretory responses to cholinergic and adrenergic sialogogues in mice.
Topics: Acetylcholine; Animals; Autonomic Nervous System; Diabetes Mellitus, Experimental; Isoproterenol; Male; Mice; Mice, Inbred Strains; Norepinephrine; Phenylephrine; Pilocarpine; Saliva; Salivary Glands; Salivation; Secretory Rate; Stimulation, Chemical; Streptozocin | 1996 |
Glucose transport and glucose transporter GLUT4 are regulated by product(s) of intermediary metabolism in cardiomyocytes.
Topics: 3-Hydroxybutyric Acid; 3-O-Methylglucose; Animals; Biological Transport; Cells, Cultured; Deoxyglucose; Diabetes Mellitus, Experimental; Energy Metabolism; Enzyme Inhibitors; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 4; Hydroxybutyrates; Insulin; Lactic Acid; Monosaccharide Transport Proteins; Muscle Proteins; Myocardium; Phenylephrine; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Rats, Wistar; Substrate Specificity; Transaminases | 1997 |
Effects of aminoguanidine and N(G)-nitro-L-arginine methyl ester on vascular responses of aortae and lungs from streptozotocin-diabetic rats.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Diabetes Mellitus, Experimental; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; Guanidines; Lung; Male; NG-Nitroarginine Methyl Ester; Phenylephrine; Rats; Rats, Wistar; Vasodilation | 1997 |
Effects of adrenergic stimulation on sciatic nerve blood flow in diabetic and control rats.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Diabetes Mellitus, Experimental; Heart Rate; Laser-Doppler Flowmetry; Male; Norepinephrine; Phenylephrine; Rats; Rats, Wistar; Sciatic Nerve; Tyramine; Vascular Resistance | 1997 |
Nitric oxide inhibition simulates the enhancement of alpha 1 agonist-induced vasoconstriction in diabetes.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Diabetes Mellitus, Experimental; In Vitro Techniques; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phenylephrine; Quinoxalines; Rats; Rats, Sprague-Dawley; Vasoconstriction | 1997 |
Vascular action of the hypoglycaemic agent gliclazide in diabetic rabbits.
Topics: Acetylcholine; Animals; Aorta, Abdominal; Blood Glucose; Diabetes Mellitus, Experimental; Endothelium, Vascular; Gliclazide; Hypoglycemic Agents; In Vitro Techniques; Insulin; Isometric Contraction; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Phenylephrine; Rabbits | 1998 |
Reproductive endocrinopathy in acute streptozotocin-induced diabetic male rats. Studies on LHRH.
Topics: Adrenergic alpha-Agonists; Animals; Diabetes Mellitus, Experimental; Gonadotropin-Releasing Hormone; Hypothalamus; Insulin; Male; Median Eminence; Neurons; Orchiectomy; Phenylephrine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Testosterone | 1998 |
In vivo cardiovascular reactivity and baroreflex activity in diabetic rats.
Topics: Adrenocorticotropic Hormone; Animals; Anticonvulsants; Baroreflex; Blood Pressure; Diabetes Mellitus, Experimental; Heart Rate; Male; Nitroprusside; Peptide Fragments; Phenylephrine; Rats; Rats, Wistar; Vasoconstrictor Agents; Vasodilator Agents | 1998 |
Effects of diabetes and treatment with the antioxidant alpha-lipoic acid on endothelial and neurogenic responses of corpus cavernosum in rats.
Topics: Acetylcholine; Animals; Antioxidants; Atropine; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Electric Stimulation; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Penis; Phenylephrine; Rats; Rats, Sprague-Dawley; Thioctic Acid | 1999 |
Augmentation of diabetes-associated renal hyperfiltration and nitric oxide production by pregnancy in rats.
Topics: Acetylcholine; Albuminuria; Animals; Aorta, Thoracic; Blood Pressure; Creatinine; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Female; Glomerular Filtration Rate; In Vitro Techniques; Kidney; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Phenylephrine; Pregnancy; Pregnancy in Diabetics; Rats; Rats, Sprague-Dawley; Renal Plasma Flow; Sodium; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
Increased activity of H2O2 in aorta isolated from chronically streptozotocin-diabetic rats: effects of antioxidant enzymes and enzymes inhibitors.
Topics: Amitrole; Animals; Antioxidants; Aorta; Catalase; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Endothelium, Vascular; Enzyme Inhibitors; Estradiol; Hydrogen Peroxide; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Oxidants; Phenylephrine; Rats; Streptozocin; Superoxide Dismutase; Vasoconstrictor Agents | 1999 |
Effect of early stage of experimental diabetes on vascular functions in isolated perfused kidneys.
Topics: Animals; Arginine; Carbachol; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Fructosamine; Glycated Hemoglobin; Male; Nitric Oxide; Nitroprusside; Norepinephrine; Perfusion; Phenylephrine; Random Allocation; Rats; Rats, Wistar; Renal Insufficiency; Time Factors; Vascular Resistance; Vasodilator Agents | 1999 |
Effects of chelator treatment on aorta and corpus cavernosum from diabetic rats.
Topics: Acetylcholine; Animals; Aorta; Blood Glucose; Chelating Agents; Diabetes Mellitus, Experimental; Electric Stimulation; Endothelium, Vascular; Male; Muscle Relaxation; Nitroglycerin; Nitroprusside; Penis; Phenylephrine; Rats; Rats, Sprague-Dawley; Trientine; Vasodilator Agents | 1999 |
Erigeron breviscapus prevents defective endothelium-dependent relaxation in diabetic rat aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Glucose; Diabetes Mellitus, Experimental; Endothelium, Vascular; Enzyme Inhibitors; Male; Muscle Contraction; Muscle Relaxation; Phenylephrine; Plants, Medicinal; Rats; Rats, Wistar | 1999 |
Modification of vasodilator response in streptozotocin-induced diabetic rat.
Topics: Adenylyl Cyclases; Animals; Aorta, Thoracic; Cromakalim; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Interactions; Heart; Iloprost; Male; Mesenteric Arteries; Phenylephrine; Potassium Channels; Rats; Rats, Sprague-Dawley; Signal Transduction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 1999 |
The effect of long-term streptozotocin-induced diabetes on contractile and relaxation responses of coronary arteries: selective attenuation of CGRP-induced relaxations.
Topics: Acetylcholine; Adrenergic beta-Agonists; Animals; Calcitonin Gene-Related Peptide; Coronary Vessels; Diabetes Mellitus, Experimental; Drug Implants; Female; Hemoglobin A; Hypoglycemic Agents; In Vitro Techniques; Insulin; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Norepinephrine; Phenylephrine; Rats; Rats, Wistar; Serotonin; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
Early detection of cardiovascular autonomic neuropathy in diabetic pigs using blood pressure and heart rate variability.
Topics: Adrenergic beta-Antagonists; Analysis of Variance; Animals; Atropine; Autonomic Nervous System Diseases; Blood Pressure; Cardiovascular Diseases; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Heart Rate; Male; Nitroprusside; Parasympatholytics; Phenylephrine; Propranolol; Respiration; Signal Processing, Computer-Assisted; Swine; Swine, Miniature; Sympathomimetics | 2000 |
Time course of changes in endothelium-dependent and -independent relaxation of chronically diabetic aorta: role of reactive oxygen species.
Topics: Acetylcholine; Amitrole; Animals; Aorta, Thoracic; Blood Glucose; Body Weight; Catalase; Chronic Disease; Deferoxamine; Diabetes Mellitus, Experimental; Ditiocarb; Dose-Response Relationship, Drug; Endothelium, Vascular; Free Radical Scavengers; In Vitro Techniques; Male; Mannitol; Nitroprusside; Phenylephrine; Rats; Superoxide Dismutase; Time Factors; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2000 |
Effects of ouabain on the pressor response to phenylephrine and on the sodium pump activity in diabetic rats.
Topics: Anesthesia; Animals; Blood Pressure; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Male; Nitric Oxide; Ouabain; Phenylephrine; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Streptozocin | 2000 |
Effect of dietary vitamin E supplementation on vascular reactivity of thoracic aorta in streptozotocin-diabetic rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Glucose; Body Weight; Calcimycin; Diabetes Mellitus, Experimental; Dietary Supplements; Dose-Response Relationship, Drug; In Vitro Techniques; Liver; Lung; Male; Malondialdehyde; Nitroprusside; Phenylephrine; Potassium Chloride; Rats; Serotonin; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Vitamin E | 2001 |
Relaxation effect of nitric oxide-donor on diabetic penile smooth muscle in vitro.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Alloxan; Animals; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Drug Interactions; Erectile Dysfunction; Macaca fascicularis; Male; Muscle, Smooth; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Norepinephrine; Penicillamine; Penis; Phenylephrine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Purines; Sildenafil Citrate; Sulfones; Vasodilator Agents | 2000 |
Effects of peroxynitrite on the reactivity of diabetic rat aorta.
Topics: Acetylcholine; Animals; Aorta; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Endothelium, Vascular; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Phenylephrine; Rats; Rats, Wistar; Sodium Nitrite; Vasoconstrictor Agents; Vasodilator Agents | 2001 |
Effect of alpha-lipoic acid on vascular responses and nociception in diabetic rats.
Topics: Animals; Antioxidants; Blood Flow Velocity; Diabetes Mellitus, Experimental; Endothelium, Vascular; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Pain; Phenylephrine; Rats; Rats, Sprague-Dawley; Superior Cervical Ganglion; Thioctic Acid; Vasoconstrictor Agents; Vasodilation | 2001 |
Attenuation of the afferent limb of the baroreceptor reflex in streptozotocin-induced diabetic rats.
Topics: Animals; Blood Pressure; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Heart Rate; Male; Neurons, Afferent; Phenylephrine; Pressoreceptors; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Solitary Nucleus; Sympathomimetics | 2001 |
Contractile responses of diabetic rat aorta to phenylephrine at different stages of diabetic duration.
Topics: Adrenergic alpha-Agonists; Age Factors; Animals; Aorta, Thoracic; Calcium; Calcium Channels; Diabetes Mellitus, Experimental; In Vitro Techniques; Indoles; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Rats; Rats, Wistar; Time Factors | 2001 |
Transient elevation of cardiac beta-adrenoceptor responsiveness and receptor number in the streptozotocin-diabetic rat.
Topics: Animals; Binding Sites; Blood Glucose; Calcium; Diabetes Mellitus, Experimental; Dihydroalprenolol; Female; Heart Atria; Insulin; Isoproterenol; Myocardial Contraction; Myocardium; Papillary Muscles; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1992 |
The alterations of norepinephrine and acetylcholine concentrations in immature rat urinary bladder caused by streptozotocin-induced diabetes.
Topics: Acetylcholine; Age Factors; Animals; Diabetes Mellitus, Experimental; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Norepinephrine; Phenylephrine; Rats; Rats, Inbred Strains; Streptozocin; Urinary Bladder | 1992 |
Diabetes mellitus impairs neurogenic and endothelium-dependent relaxation of rabbit corpus cavernosum smooth muscle.
Topics: Acetylcholine; Animals; Diabetes Mellitus, Experimental; Electric Stimulation; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Muscle, Smooth; Nitroprusside; Papaverine; Penis; Phenylephrine; Rabbits | 1992 |
Influence of diabetes mellitus on renal vascular responses to bradykinin.
Topics: Animals; Bradykinin; Diabetes Mellitus, Experimental; Dinoprostone; Kidney; Kidney Cortex; Kidney Medulla; Male; Microsomes; Mitochondria; Phenylephrine; Phospholipases A; Phospholipases A2; Rats; Rats, Wistar; Reference Values; Renal Circulation | 1992 |
Endothelium-dependent increase in vascular sensitivity to phenylephrine in long-term streptozotocin diabetic rat aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Diabetes Mellitus, Experimental; Endothelium, Vascular; Indomethacin; Insulin; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Phenylephrine; Rats; Rats, Sprague-Dawley; Vasoconstriction | 1992 |
Adrenergic activation of glycogen phosphorylase in primary culture diabetic cardiomyocytes.
Topics: Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Activation; Epinephrine; Heart; Kinetics; Male; Myocardium; Phenylephrine; Phosphorylases; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Reference Values | 1992 |
Hormone-stimulated glucose production from glycogen in hepatocytes from streptozotocin diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Enzyme Activation; Glucagon; Glucose; Glucose-6-Phosphatase; Glycogen; Hormones; Liver; Microsomes; Phenylephrine; Phosphorylases; Reference Values; Vasopressins | 1991 |
Activities of enzymes of glycerolipid synthesis in brown adipose tissue after treatment of rats with the adrenergic agonists BRL 26830A and phenylephrine, after exposure to cold and in streptozotocin-diabetes.
Topics: Adipose Tissue, Brown; Adrenergic beta-Agonists; Animals; Cold Temperature; Diabetes Mellitus, Experimental; Ethanolamines; Fatty Acid Synthases; Glycerol-3-Phosphate O-Acyltransferase; Lipids; Male; Phenylephrine; Phosphatidate Phosphatase; Rats; Rats, Inbred Strains | 1991 |
Intestinal mucin secretion in streptozotocin-diabetic rats: lack of response to cholinergic stimulation and cholera toxin.
Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Cholera Toxin; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Intestinal Mucosa; Intestine, Small; Isoproterenol; Male; Mucins; Phentolamine; Phenylephrine; Propranolol; Rats; Rats, Inbred Strains; Reference Values; Streptozocin | 1991 |
Influences of thyroid status and sympathoadrenal system on extrarenal potassium disposal.
Topics: Adrenal Glands; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Diabetes Mellitus, Experimental; Epinephrine; Hyperthyroidism; Kidney; Male; Phenoxybenzamine; Phentolamine; Phenylephrine; Potassium; Rats; Rats, Inbred Strains; Reference Values; Thyroid Gland; Thyroidectomy; Thyroxine; Triiodothyronine | 1990 |
Effect of diabetes mellitus on disruption of the blood-brain barrier during acute hypertension.
Topics: Animals; Blood Glucose; Blood Pressure; Blood-Brain Barrier; Body Weight; Diabetes Mellitus, Experimental; Hypertension; Microcirculation; Phenylephrine; Rats; Reference Values | 1990 |
Renal vascular responsiveness to arachidonic acid in experimental diabetes.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Dinoprostone; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Phenylephrine; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Rats; Rats, Inbred Strains; Receptors, Prostaglandin; Renal Circulation; Thromboxane A2 | 1990 |
Beneficial effect of an ACTH-(4-9) analog on peripheral neuropathy and blood pressure response to tyramine in streptozocin diabetic rats.
Topics: Adrenocorticotropic Hormone; Animals; Blood Pressure; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Hydroxydopamines; Male; Oxidopamine; Peptide Fragments; Phenylephrine; Rats; Rats, Inbred Strains; Tyramine | 1990 |
The effects of testosterone or insulin treatment on contractile responses of the rat vas deferens following castration or streptozotocin-induced diabetes mellitus.
Topics: Animals; Blood Glucose; Calcium; Carbachol; Diabetes Mellitus, Experimental; Electric Stimulation; Insulin; Male; Muscle Contraction; Muscle, Smooth; Orchiectomy; Organ Size; Phenylephrine; Rats; Rats, Inbred Strains; Testis; Testosterone; Vas Deferens | 1990 |
Contribution of the arterial tissue to vascular pathology in diabetes mellitus.
Topics: Animals; Arteries; Diabetes Mellitus, Experimental; In Vitro Techniques; Male; Papaverine; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred Strains; Vasoconstriction; Vasodilation | 1990 |
Vascular responses to agonists in rat mesenteric artery from diabetic rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Diabetes Mellitus, Experimental; In Vitro Techniques; Isometric Contraction; Male; Mesenteric Arteries; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Phenylephrine; Potassium; Rats; Rats, Inbred Strains; Serotonin | 1987 |
Mechanisms of increased responses of the aorta to alpha-adrenoceptor agonists in streptozotocin-induced diabetic rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Calcium; Calcium Channels; Diabetes Mellitus, Experimental; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Phosphatidylinositols; Rats; Rats, Inbred Strains | 1988 |
Histamine relaxation of aortic rings from diabetic rats.
Topics: Animals; Aorta, Thoracic; Diabetes Mellitus, Experimental; Diphenhydramine; Endothelium, Vascular; Histamine; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Phenylephrine; Rats; Rats, Inbred Strains; Time Factors | 1989 |
Effects of streptozotocin-induced hyperglycemia on agonist-stimulated phosphatidylinositol turnover in rat aorta.
Topics: Animals; Aorta, Thoracic; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Hyperglycemia; In Vitro Techniques; Inositol; Inositol Phosphates; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenylephrine; Phosphatidylinositols; Rats; Rats, Inbred Strains; Reference Values; Serotonin; Streptozocin; Sugar Phosphates | 1989 |
Altered responsiveness of diabetic dog renal arteries to acetylcholine and phenylephrine: role of endothelium.
Topics: Acetylcholine; Animals; Arteries; Diabetes Mellitus, Experimental; Dogs; Endothelium, Vascular; Female; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitroprusside; Phenylephrine | 1989 |
Comparison of the effects of castration and streptozotocin-induced diabetes mellitus on contractile responses of the rat vas deferens.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Diabetes Mellitus, Experimental; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Orchiectomy; Organ Size; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred Strains; Testis; Testosterone; Vas Deferens | 1989 |
Enhanced vascular alpha-adrenergic neuroeffector system in diabetes: importance of calcium.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Clonidine; Diabetes Mellitus, Experimental; Electric Stimulation; Endothelium, Vascular; Guanabenz; Male; Mesenteric Arteries; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1988 |
Myocardial calcium uptake in streptozotocin diabetic and control rats after dibutyryl-cAMP; alpha-adrenergic stimulation and calcium deprivation.
Topics: Animals; Bucladesine; Calcium; Diabetes Mellitus, Experimental; In Vitro Techniques; Isoproterenol; Male; Myocardium; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1985 |
Alterations in alpha 1-adrenoceptor stimulation of isolated atria from experimental diabetic rats.
Topics: Animals; Blood Glucose; Calcium; Diabetes Mellitus, Experimental; Heart; Heart Atria; In Vitro Techniques; Insulin; Kinetics; Male; Myocardial Contraction; Myocardium; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Timolol | 1986 |
Insulin induced reversibility of altered responsiveness in femoral arterial bed of diabetic dogs.
Topics: Animals; Blood Pressure; Diabetes Mellitus, Experimental; Dogs; Female; Femoral Artery; Insulin; Male; Norepinephrine; Phenylephrine; Reference Values; Regional Blood Flow | 1988 |
Impairment of endothelium-dependent relaxation in aortae from spontaneously diabetic rats.
Topics: Acetylcholine; Animals; Aorta; Biological Products; Calcimycin; Diabetes Mellitus, Experimental; Nitric Oxide; Phenylephrine; Rats; Rats, Inbred BB | 1988 |
[Diabetic changes in pupillary reaction and iridal pathology. No. 1. The role of aldose reductase to the delayed pupillary reaction in galactose-fed rats].
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Imidazoles; Imidazolidines; Male; Naphthalenes; Phenylephrine; Pupil; Rats; Rats, Inbred Strains; Sugar Alcohol Dehydrogenases | 1988 |
Role of alpha-adrenergic hormones in potassium homeostasis in the rat.
Topics: Adrenalectomy; Animals; Bicarbonates; Blood Glucose; Diabetes Mellitus, Experimental; Homeostasis; Hydrogen-Ion Concentration; Insulin; Male; Nephrectomy; Phentolamine; Phenylephrine; Potassium; Potassium Chloride; Rats; Rats, Inbred Strains; Sympathectomy, Chemical | 1987 |
Contractile and relaxant responses of diabetic dog femoral arteries.
Topics: Acetylcholine; Animals; Diabetes Mellitus, Experimental; Dogs; Endothelium, Vascular; Female; Femoral Artery; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine | 1988 |
Supersensitivity and endothelium dependency of histamine-induced relaxation in mesenteric arteries isolated from diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Endothelium; Histamine; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Rats; Rats, Inbred Strains | 1986 |
Streptozocin-induced diabetes affects rat urinary bladder response to autonomic agents.
Topics: Acetylcholine; Animals; Autonomic Agents; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dose-Response Relationship, Drug; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Phenylephrine; Rats; Rats, Inbred Strains; Urinary Bladder | 1985 |
Adrenergic changes due to pertussis: insulin, glucose and free fatty acids.
Topics: Adrenalectomy; Adrenergic beta-Antagonists; Animals; Biological Assay; Blood Glucose; Diabetes Mellitus, Experimental; Endocrine Glands; Fasting; Fatty Acids, Nonesterified; Hypophysectomy; Insulin; Isoproterenol; Norepinephrine; Pertussis Vaccine; Phenoxybenzamine; Phenylephrine; Rats; Sympathomimetics; Theophylline | 1969 |
Changes of adrenergic reaction pattern in experimental diabetes mellitus.
Topics: Animals; Aorta; Cold Temperature; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Norepinephrine; Phentolamine; Phenylephrine; Prednisolone; Propranolol; Rabbits | 1973 |