phenylephrine has been researched along with Aging in 222 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 47 (21.17) | 18.7374 |
| 1990's | 88 (39.64) | 18.2507 |
| 2000's | 55 (24.77) | 29.6817 |
| 2010's | 27 (12.16) | 24.3611 |
| 2020's | 5 (2.25) | 2.80 |
| Authors | Studies |
|---|---|
| Kang, J; Lee, S; Liang, S; Mohan, S; Morgan, KG; Nicholson, CJ; O'Rourke, C; Xing, Y | 1 |
| Broderick, GA; Pathak, RA | 1 |
| Askew-Page, HR; Bagher, P; Biwer, LA; Good, ME; Hong, K; Isakson, BE; Johnstone, SR; Macal, E; Milstein, J; Sonkusare, SK | 1 |
| Calderón, JC; Cupitra, NI; Narvaez-Sanchez, R | 1 |
| Chaudhary, P; Das-Earl, P; Schreihofer, AM | 1 |
| Chess-Williams, R; Lim, I; Sellers, D | 1 |
| Baretella, O; Vanhoutte, PM; Xu, A | 1 |
| Bourque, SL; Davidge, ST; Gragasin, FS | 1 |
| Dantas, AP; Garabito, M; Hermenegildo, C; Medina, P; Mompeón, A; Novella, S; Segarra, G; Vidal-Gómez, X | 1 |
| Gao, YZ; Morgan, KG; Saphirstein, RJ; Suki, B; Yamin, R | 1 |
| Arnold, AC; Diz, DI | 1 |
| Owaki, H; Sadahiro, S; Takaki, M | 1 |
| Crestani, CC; Cruz, FC; Duarte, JO; Hummel, LF; Leão, RM; Planeta, CS | 1 |
| Cruz, M; García-Macedo, R; Gómez-Zamudio, JH; Ibarra-Barajas, M; Kumate, J; Lázaro-Suárez, M | 1 |
| Barton, M; Fredette, NC; Meyer, MR; Prossnitz, ER | 1 |
| Ando, M; Iguchi, M; Kobayashi, T; Matsumoto, T; Taguchi, K; Watanabe, S; Yamada, K | 1 |
| Chongsa, W; Jansakul, C; Kanokwiroon, K | 1 |
| Dell'Acqua, ML; Hinke, SA; Hirenallur-Shanthappa, D; Langeberg, LK; Navedo, M; Nieves-Cintrón, M; Nygren, PJ; Santana, LF; Scott, JD | 1 |
| Seawright, JW; Trache, A; Wilson, E; Woodman, CR | 1 |
| Chang, F; Flavahan, NA; Flavahan, S | 1 |
| Lee, S; Morgan, KG; Nicholson, CJ; Seta, F | 1 |
| Dmitrieva, N; Nagabukuro, H; Zhang, G | 1 |
| Ahrabi, AK; Balligand, JL; Caron, N; Desjardins, F; Devuyst, O; Horie, S; Morel, N; Vandenberg, G | 1 |
| Nishiyama, SK; Richardson, RS; Wray, DW | 1 |
| Dimsdale, J; Fainman, C; Liu, F; Milic, M; Mills, PJ; Sun, P; Ziegler, MG | 1 |
| Davidge, ST; Gragasin, FS | 1 |
| Al-Khairi, I; Baharnoori, M; Bhardwaj, SK; Kamath, A; Srivastava, LK | 1 |
| Cao, YF; Ge, YH; Liu, ZQ; Song, JG; Song, SL; Sun, YM; Xu, XW; Yang, LQ; Yu, WF | 1 |
| Graham, DA; Rush, JW | 1 |
| Corrêa, FM; de Andrade, CR; de Oliveira, AM | 1 |
| Evanson, KW; Kluess, HA; Stone, AJ | 1 |
| Adams, MA; Adams, SM; Blaser, MC; Hannan, JL; Oldfield, L; Pang, JJ; Pang, SC | 1 |
| Butterworth, K; Casas-Dolz, R; Frederick, J; Giguère, S; Pellegrini-Masini, A; Turpin, MM | 1 |
| Béraud, G; Boulanger, E; Bulckaen, H; Creusy, C; Fontaine, P; Gaxatte, C; Prévost, G; Puisieux, F | 1 |
| Gooi, JH; Lotgering, FK; Pertijs, J; Ploemen, IH; Smits, P; Spaanderman, ME; Sweep, FC; van Drongelen, J | 1 |
| Hotta, H; Uchida, S; Watanabe, N | 1 |
| Crecelius, AR; Dinenno, FA; Kirby, BS; Voyles, WF | 1 |
| Bers, DM; Bossuyt, J; Bossuyt, S; Campbell, KS; Chang, CW; Helmstadter, K; Kunkel, MT; Martin, JL; Newton, AC; Robia, SL | 1 |
| Anton, MM; Buckwalter, JB; Clifford, PS; Delorey, DS; Dincer, UD; Kluess, HA; Mittelstadt, S; Tune, JD | 1 |
| Falcone, JC; Fleming, JT; Passmore, JC; Tyagi, SC | 1 |
| Dantas, AP; Heras, M; Jiménez-Altayó, F; Onetti, Y; Vila, E | 1 |
| Briones, A; D'Ocon, P; Ivorra, MD; Moreno, A; Rubio, C; Vila, E | 1 |
| Bruneval, P; Deplanne, V; Heudes, D; Lluel, P; Palea, S | 1 |
| Li, NS; Li, YJ; Lu, R; Peng, J; Zhu, HQ | 1 |
| Hodges, RR; Kublin, CL; Zoukhri, D | 1 |
| Brink, P; Matthews, G; Walcott, B | 1 |
| Christou, DD; Jones, PP; Jordan, J; Seals, DR | 1 |
| Iwase, S; Mano, T; Matsukawa, T; Sugiyama, Y | 1 |
| Khalil, RA; Payne, JA; Reckelhoff, JF | 1 |
| ARMALY, MF; HALASA, AH | 1 |
| Christou, DD; Jones, PP; Pimentel, AE; Seals, DR | 1 |
| Carson, LD; Delp, MD; Hunter, JC; Korzick, DH; McDowell, MK; Tickerhoof, MM | 1 |
| Li, Y; van den Pol, AN | 1 |
| Ariznavarreta, MC; Cachofeiro, V; Castillo, C; Gil-Loyzaga, P; Lahera, V; Tresguerres, JA | 1 |
| Crozatier, B; Guenoun, T; Laplace, M; Le Corvoisier, P; Montagne, O | 1 |
| Dinenno, FA; Joyner, MJ; Masuki, S | 1 |
| Hester, RL; Naik, JS; Xiang, L | 1 |
| Briones, AM; Giraldo, J; Montoya, N; Vila, E | 1 |
| Cheng, L; Jiang, LQ; Krawczyk, M; Lakatta, EG; Monticone, R; Pintus, G; Spinetti, G; Talan, M; Wang, M; Zhang, J; Zhao, D | 1 |
| Berkowitz, DE; Champion, HC; Hare, JM; Li, D; Nyhan, D; Ryoo, S; Shoukas, AA; Steppan, J; Wang, D; White, AR | 1 |
| del Corsso, C; Gurney, AM; Hatton, WJ; McAllister, CE; Murray, K; Ostrovskaya, O; Spencer, NJ; Wilson, SM | 1 |
| Brands, MW; Dorrance, AM; Smith, AD; Wang, MH | 1 |
| Au, CL; Fung, KP; Huang, Y; Laher, I; Tsang, SY; Vanhoutte, PM; Wong, CM; Yao, X | 1 |
| Levy, WC; Madden, KM; Stratton, JR | 1 |
| Cardinali, DP; Linares, LM; Obaya-Naredo, D; Pinto, JE; Planells, FM; Reyes-Toso, CF; Ricci, CR | 1 |
| Adeagbo, AS; Awe, SO | 1 |
| Berger, I; Gero, D; Karck, M; Radovits, T; Seres, L; Szabó, C; Szabó, G | 1 |
| Ito, O; Kanazawa, M; Kohzuki, M; Kurosawa, H; Minami, N; Mori, N; Nagasaka, M; Ogawa, M | 1 |
| Dinenno, FA; Kirby, BS; Markwald, RR; Smith, EG; Voyles, WF | 1 |
| Donato, AJ | 1 |
| Mandel, DA; Mobley, SC; Schreihofer, AM; Stepp, DW | 1 |
| de Cabo, C; de Mera, RM; Jordán, J; Lloréns, S; Mendizábal, Y; Nava, E; Pascual, A; Prieto-Martín, A | 1 |
| Behnke, BJ; Delp, MD; Prisby, RD; Ramsey, MW | 1 |
| Tang, EH; Vanhoutte, PM | 1 |
| Boulanger, E; Bulckaen, H; Corman, B; Creusy, C; Garçon, G; Gaxatte, C; Gosset, P; Prévost, G; Puisieux, F; Robitaille, G; Roquet, V; Shirali, P | 1 |
| Berezan, DJ; Davidge, ST; Dunn, KM; Falck, JR | 1 |
| Imanishi, A; Latifpour, J; Yamamoto, Y; Yono, M; Yoshida, M | 1 |
| Chen, H; Guo, J; Lu, AY; Qian, FL; Sun, MW; Tao, T; Wang, J; Wang, L | 1 |
| Baum, BJ; Hoopes, MT; Ito, H; Roth, GS | 1 |
| Fukuzaki, H; Kusui, A; Sakamoto, S; Yokoyama, M | 1 |
| Mapstone, R | 1 |
| Gerald, MC; Kolta, MG; Wallace, LJ | 1 |
| Smith, SA; Smith, SE | 1 |
| Blair, JB; Ray, PD; Yorek, MA | 1 |
| Couch, MW; Crowley, JR; Fregly, MJ; Threatte, RM; Williams, CM | 1 |
| Bedarida, G; Blaschke, TF; Bushell, E; Hoffman, BB | 1 |
| Adachi, M; Manita, S; Matsuda, T; Shigenobu, K; Tanaka, H | 1 |
| Gao, L; Kennedy, JM; Solaro, RJ | 1 |
| Haidet, GC; Rector, TS; Wennberg, PW | 1 |
| McWeeny, OJ; Merrill, DC; Robillard, JE; Segar, JL; Smith, BA | 1 |
| Guillery, EN; Jose, PA; Merrill, DC; Nakamura, KT; Robillard, JE; Segar, JL | 1 |
| Leenen, FH; White, M | 1 |
| Faraci, FM; Heistad, DD; Paternò, R | 1 |
| Benzoni, D; Boussairi, EH; Sacquet, J; Sassard, J | 1 |
| Huang, BS; Leenen, FH | 1 |
| Nedvídek, J; Zicha, J | 2 |
| Li, K; Rouleau, JL | 1 |
| Berkenboom, G; Brékine, D; Fontaine, J; Unger, P | 1 |
| Karpinski, E; Liu, QY; Pang, PK | 1 |
| Bertrand, H; Herlihy, JT; Stacy, C; Thomas, J | 1 |
| Qualy, JM; Westfall, TC | 1 |
| Advenier, C; Ansay, M; Gustin, P | 1 |
| Shonis, CA; Waldrop, TG | 1 |
| Buñag, RD; Itoh, H | 1 |
| Dong, XW; Gozal, D; Harper, RM; Rector, DM | 1 |
| Dignan, RJ; Kadletz, M; Wechsler, AS | 1 |
| Kajiyama, Y; Sanai, Y; Ui, M | 1 |
| Hastings, JA; Morris, MJ; Pavia, JM | 1 |
| Franchini, KG; Ida, F; Krieger, EM; Moreira, ED | 1 |
| Buñag, RD; Davidow, LW | 2 |
| Kanai, S; Koike, K; Otsuki, H; Sato, M; Takayanagi, K | 1 |
| James, MA; Panerai, RB; Potter, JF; Robinson, TG | 1 |
| Kanai, S; Koike, K; Ohtsuki, H; Satoh, M; Takayanagi, I | 1 |
| Brodde, OE; Nedelka, G; Poller, U; Pönicke, K; Radke, J | 1 |
| Bunting, S; Cheng, J; Jin, H; King, KL; Ko, A; Lai, J; Li, W; Paoni, NF; Winer, J; Yang, R; Yen, R; Zeigler, F | 1 |
| Davidge, ST; Hubel, CA; McLaughlin, MK | 1 |
| Ibarra, M; López-Guerrero, JJ; Terrón, JA; Villalobos-Molina, R | 1 |
| Faintrenie, G; Géloën, A | 1 |
| Ehsani, AA; Spina, RJ; Turner, MJ | 1 |
| Brubakk, AM; Jynge, P; Karlsson, JO; Lossius, K; Støen, R; Vik, T | 1 |
| Fraeyman, N; Van Ermen, A | 1 |
| Flahive, WJ; Gilmour, RF; Kornreich, B; Moïse, NS; Riccio, ML | 1 |
| de Avellar, MC; Markus, RP | 1 |
| Buñag, RD; Kerecsen, L; Mellick, JR; Montemayor, E | 1 |
| Campos-Mello, C; Correa, FM; de Oliveira, AM; Leitão, MC | 1 |
| Cachofeiro, V; Lahera, V; Maeso, R; Muñoz-García, R; Navarro-Cid, J; Rodrigo, E; Ruilope, LM | 1 |
| Ehsani, AA; Mier, CM; Spina, RJ; Turner, MJ | 1 |
| Fourney, A; Leenen, FH; Mikes, E; White, M | 1 |
| Chapman, J; Mader, SL; Schutzer, WE; Watts, VJ | 1 |
| Allen, B; Buñag, R; Mellick, J | 1 |
| Ibarra, M; López-Guerrero, JJ; Villalobos-Molina, R | 1 |
| Crossman, AA; Eckberg, DL; Halliwill, JR; Kuusela, TA; Morillo, CA; Rudas, L; Tahvanainen, KU | 1 |
| Aisaka, K; Kawabe, K; Moriyama, N; Nishimatsu, H; Okaya, Y; Suzuki, Y | 1 |
| Davidge, ST; O'brien, SF; Russell, JC | 1 |
| Berkowitz, DE; Booth, JV; Cozart, KL; D'Amico, EB; El-Moalem, H; Funk, BL; Marucci, L; Page, SO; Richardson, CD; Rudner, XL; Schwinn, DA; Winters, B | 1 |
| Aisaka, K; Kanada, A; Kawabe, K; Moriyama, N; Okaya, Y; Suzuki, Y | 1 |
| Barras, M; Bruneval, P; Corman, B; Grandadam, F; Heudes, D; Lluel, P; Martin, DJ; Palea, S | 1 |
| Bertinieri, G; Dell'Oro, R; Grassi, G; Mancia, G; Seravalle, G; Stella, ML; Turri, C | 1 |
| Kang, KB; Majewski, H; van der Zypp, A | 1 |
| Ahmed, H; Aisaka, K; Akiyama, K; Fukasawa, R; Kitamura, T; Moriyama, N; Nishimatsu, H; Suzuki, Y; Tanaka, Y; Tatemichi, S | 1 |
| Cestari, IA; Ida, F; Irigoyen, MC; Krieger, EM; Moreira, ED; Pires, MD; Werner, A | 1 |
| Bucca, C; Cacciafesta, M; Lionetti, M; Marigliano, V; Moisè, A; Nocco, M; Piccirillo, G; Santagada, E; Tarantini, S; Viola, E | 1 |
| Besse, S; Boucher, F; de Leiris, J; Tanguy, S; Toufektsian, MC | 1 |
| Asai, K; Kudej, AB; Kudej, RK; Natividad, F; Shen, YT; Takagi, G; Vatner, DE; Vatner, SF | 1 |
| Jones, PP; Jordan, J; Keisling, GA; Quaife, RA; Seals, DR; Shannon, JR; Shapiro, LF | 1 |
| Besse, S; Boucher, F; Bulteau, AL; de Leiris, J; Le Page, C; Riou, B; Swynghedauw, B; Tanguy, S | 1 |
| Besse, S; Boucher, F; Bulteau, AL; de Leiris, J; Riou, B; Swynghedauw, B; Tanguy, S | 1 |
| Maloney, JA; Wheeler-Clark, ES | 1 |
| Park, MK; Sheridan, PH | 1 |
| Claycomb, WC | 1 |
| Sleight, P | 1 |
| Nukari-Siltovuori, A | 1 |
| Fortuin, NJ; Guarnieri, T; Lakatta, EG; Raizes, GS; Spurgeon, HA; Weisfeldt, ML; Yin, FC | 1 |
| Feldman, RD | 1 |
| Buñag, RD; Teräväinen, TL | 2 |
| Borkowski, KR; Gros, R; Schneider, H | 1 |
| Aalkjaer, C; Hasenkam, JM; Mortensen, FV; Nielsen, H; Pilegaard, HK | 1 |
| Leenen, FH; Yuan, B | 1 |
| Hiramatsu, Y; Itokazu, Y; Kinoshita, T; Koida, M; Kurio, W; Maeda, H; Manno, K; Nakamuta, H; Ogawa, Y; Ozaki, K | 1 |
| Blaschke, TF; Dachman, WD; Ford, GA; Hoffman, BB | 1 |
| Dananberg, J; Grekin, RJ; Tummala, PE | 1 |
| Aliev, G; Cirillo, R; Italiano, G; Prosdocimi, M | 1 |
| Alper, RH | 1 |
| Albergati, F; Daffonchio, A; Ferrari, AU; Mancia, G | 1 |
| Christ, GJ; Melman, A; Stone, B | 1 |
| Christ, GJ; Maayani, S; Melman, A; Valcic, M | 1 |
| Blaschke, TF; Ford, GA; Hoffman, BB | 1 |
| Cervenka, JH; Parmer, RJ; Stone, RA | 1 |
| Chemtob, S; Guest, I; Potvin, W; Varma, DR | 1 |
| Fukui, T; Horio, T; Kohno, M; Murakawa, K; Takeda, T; Yasunari, K; Yokokawa, K | 1 |
| Barringer, DL; Buñag, RD | 2 |
| Abboud, FM; Chapleau, MW; Hajduczok, G; Johnson, SL | 1 |
| Cohen, HL; Condemi, G; Eberle, LP; Gootman, PM; Hundley, BW | 1 |
| Bowyer, JF; Burnett, DM; Masserano, JM; Zahniser, NR | 1 |
| Buñag, RD; Tanabe, S | 2 |
| Buñag, RD; Eriksson, L; Kerecsen, L | 1 |
| Ohtsuki, H; Onozuka, S; Shinkai, M; Takayanagi, I | 1 |
| Mayhan, WG | 1 |
| Buñag, RD; Eriksson, L; Krizsan, D | 1 |
| Hatake, K; Kurahashi, M; Sakamoto, K; Wakabayashi, I; Yoshimoto, S | 1 |
| Atkinson, J; Burlet, C; Capdeville, C; Chillon, JM; Henrion, D; Oster, L | 1 |
| Buñag, RD; Eriksson, L; Teräväinen, TL | 1 |
| Fox-Eastham, K; Kerber, RE; Kieso, RA; Tomanek, RJ; Vandenberg, BF | 1 |
| Bühler, FR; Dohi, Y; Lüscher, TF; Thiel, MA | 1 |
| Bromberg, BB; Cripps, MM; Welch, MH | 1 |
| Gallager, DW; Smith, DA | 1 |
| Elliott, HL; Howie, CA; Sumner, DJ | 1 |
| Chun, AL; Gerald, MC; Levin, RM; Wallace, LJ; Wein, AJ | 1 |
| Gitter, S; Nadler, E; Sagy, M; Shavit, G; Vidne, BA | 1 |
| Ellenbogen, KA; Mohanty, PK; Szentpetery, S; Thames, MD | 1 |
| Abe, K; Imai, Y; Minami, N; Munakata, M; Sasaki, S; Sekino, H; Yoshinaga, K | 1 |
| Buckley, C; Curtin, DM; Docherty, J; Eustace, P | 1 |
| Bäck, O; Bucht, G; Henriksson, R; Hörnqvist, R; Winblad, B | 1 |
| Gelband, H; McCormack, J; Pickoff, AS; Stolfi, A; Villafañe, J; Xu, H | 1 |
| Cerutti, C; Julien, C; Lo, M; Sassard, J; Su, DF; Vincent, M | 1 |
| Chambert, G; Epstein, AN; Lora-Vilchis, MC; Rodriguez-Zendejas, AM; Russek, M; Soto-Mora, LM | 1 |
| Beuckelmann, D; Böhm, M; Diet, F; Erdmann, E; Feiler, G; Lohse, MJ | 1 |
| Nowak, G; Silberring, J | 1 |
| Borkowski, KR; Quinn, P | 1 |
| Duckles, SP; Handa, RK | 1 |
| Amerini, S; Fusi, F; Ledda, F; Mantelli, L; Mugelli, A; Piazzesi, G | 1 |
| Hashimoto, K; Kato, K; Tsujimoto, A; Tsujimoto, G | 1 |
| Docherty, JR; Hyland, L; Warnock, P | 1 |
| Byard, PJ; Davis, PB | 1 |
| Chadwick, RS; Goldstein, DS; Keiser, HR | 1 |
| Blaschke, TF; Eichler, HG; Hiremath, A; Hoffman, BB; Katzir, D | 1 |
| Korkushko, OV; Moroz, GZ | 1 |
| Yin, FC | 1 |
| Campbell, R; Conlon, ME; Egan, B; Julius, S; Schork, N; Zwiefler, A | 1 |
| Rao, KM | 1 |
| Angell, CS; Rothbaum, DA; Shaw, DJ; Shock, NW | 1 |
| Braswell, R; Hiatt, RL; Patty, JW; Smith, L | 1 |
| Kuchii, M; Kurahashi, K; Shibata, S | 1 |
| Gribbin, B; Peto, R; Pickering, TG; Sleight, P | 1 |
| Gribbin, B; Pickering, TG; Sleight, P | 1 |
| Fujiwara, M; Hattori, K; Mori, J; Sakurai, I; Shibata, S | 1 |
| Bristow, JD; Gribbin, B; Honour, AJ; Pickering, TG; Sleight, P | 1 |
1 review(s) available for phenylephrine and Aging
| Article | Year |
|---|---|
Reflex control of the heart.
Topics: Aging; Animals; Arteries; Blood Pressure; Carotid Sinus; Dogs; Heart Rate; Humans; Hypertension; Mental Processes; Muscle, Smooth; Phenylephrine; Pressoreceptors; Reflex | 1979 |
6 trial(s) available for phenylephrine and Aging
| Article | Year |
|---|---|
Increased abdominal-to-peripheral fat distribution contributes to altered autonomic-circulatory control with human aging.
Topics: Abdomen; Adipose Tissue; Adult; Aged; Aging; Autonomic Nervous System; Baroreflex; Blood Pressure; Body Composition; Body Mass Index; Ganglionic Blockers; Heart; Heart Rate; Humans; Male; Middle Aged; Phenylephrine; Trimethaphan; Vagus Nerve; Vasoconstrictor Agents | 2004 |
Impaired modulation of sympathetic alpha-adrenergic vasoconstriction in contracting forearm muscle of ageing men.
Topics: Adenosine; Adrenergic alpha-Agonists; Adult; Aged; Aging; Clonidine; Forearm; Hand Strength; Humans; Male; Muscle Contraction; Muscle, Skeletal; Phenylephrine; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Sympatholytics; Tyramine; Vasoconstriction | 2005 |
Aging and cardiovascular responsiveness to beta-agonist in humans: role of changes in beta-receptor responses versus baroreflex activity.
Topics: Adult; Aged; Aging; Atropine; Baroreflex; Female; Forearm; Heart Rate; Hemodynamics; Humans; Isoproterenol; Male; Middle Aged; Myocardial Contraction; Phenylephrine; Receptors, Adrenergic, beta; Regional Blood Flow; Sex Characteristics; Trimethaphan; Vascular Resistance | 1994 |
Arterial baroreceptor-cardiac reflex sensitivity in the elderly.
Topics: Aged; Aging; Baroreflex; Female; Heart Rate; Humans; Hypertension; Male; Nitroprusside; Phenylephrine; Pressoreceptors; Valsalva Maneuver | 1996 |
Influence of aging on cardiac baroreflex sensitivity determined non-invasively by power spectral analysis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Algorithms; Analysis of Variance; Baroreflex; Blood Pressure Determination; Child; Electrocardiography; Female; Humans; Linear Models; Male; Mathematical Computing; Middle Aged; Phenylephrine; Vasoconstrictor Agents | 2001 |
Effects of ketanserin on blood pressure and platelet aggregation in elderly men with mild hypertension.
Topics: Adult; Aged; Aging; Angiotensin II; Blood Pressure; Calcium; Humans; Hypertension; Intracellular Membranes; Ketanserin; Male; Middle Aged; Osmolar Concentration; Phenylephrine; Platelet Aggregation | 1988 |
215 other study(ies) available for phenylephrine and Aging
| Article | Year |
|---|---|
Ageing causes an aortic contractile dysfunction phenotype by targeting the expression of members of the extracellular signal-regulated kinase pathway.
Topics: Aging; Animals; Extracellular Signal-Regulated MAP Kinases; Mice; MicroRNAs; Paxillin; Phenotype; Phenylephrine; Phosphorylation | 2022 |
Color Doppler Duplex Ultrasound Parameters in Men Without Organic Erectile Dysfunction.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aging; Erectile Dysfunction; Humans; Male; Middle Aged; Penile Erection; Penis; Phenylephrine; Phosphodiesterase 5 Inhibitors; Retrospective Studies; Treatment Failure; Ultrasonography, Doppler, Color; Urological Agents; Young Adult | 2020 |
Endothelial calreticulin deletion impairs endothelial function in aged mice.
Topics: Aging; Animals; Calcium Signaling; Calreticulin; Carbachol; Endothelium, Vascular; Gene Deletion; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Phenylephrine; Taurochenodeoxycholic Acid; Vasoconstrictor Agents; Vasodilation | 2020 |
Influence of Ageing on Vascular Reactivity and Receptor Expression in Rabbit Aorta: A Complement to Elastocalcinosis and Smooth Muscle Mechanisms.
Topics: Aging; Animals; Aorta; Carotid Intima-Media Thickness; Endothelium, Vascular; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Rabbits | 2020 |
Preserved glycemic control and baroreflex efficacy in young adult hypertensive female obese Zucker rats.
Topics: Aging; Animals; Baroreflex; Blood Glucose; Cholesterol; Female; Gene Expression Regulation; Glycemic Control; Hyperinsulinism; Hypertension; Insulin; Male; Obesity; Phenylephrine; Proto-Oncogene Proteins c-fos; Rats; Rats, Zucker; Sex Factors; Sympathetic Nervous System; Triglycerides | 2021 |
Altered ureteral contractility with ageing: Role of the rho-kinase pathway.
Topics: Aging; Amides; Animals; Dose-Response Relationship, Drug; Female; Mice; Muscle Contraction; Phenylephrine; Pyridines; rho-Associated Kinases; Serotonin; Swine; Ureter | 2018 |
No Protective Effect of Constitutive Activation of AMPK in Endothelial Cells on Vascular Function in Aged Obese Mice but Augmented α1-Adrenergic Contractions in Renal Arteries Reversible by Weight Loss.
Topics: Adrenergic Agents; Adrenergic alpha-1 Receptor Agonists; Aging; AMP-Activated Protein Kinases; Animals; Aorta, Thoracic; Carotid Arteries; Diet, High-Fat; Endothelial Cells; Endothelium, Vascular; Enzyme Activation; Female; Longevity; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Muscle Contraction; Muscle, Smooth, Vascular; Obesity; Phenylephrine; Receptors, Adrenergic, alpha; Renal Artery; Vasodilation; Weight Loss | 2018 |
Propofol increases vascular relaxation in aging rats chronically treated with the angiotensin-converting enzyme inhibitor captopril.
Topics: Aging; Anesthetics, Intravenous; Angiotensin-Converting Enzyme Inhibitors; Animals; Area Under Curve; Blood Pressure; Captopril; Endothelium, Vascular; Enzyme Inhibitors; Methacholine Chloride; Muscarinic Agonists; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Phenylephrine; Propofol; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents | 2013 |
Aging-related endothelial dysfunction in the aorta from female senescence-accelerated mice is associated with decreased nitric oxide synthase expression.
Topics: Acetylcholine; Aging; Animals; Aorta, Thoracic; Endothelium, Vascular; Female; Gene Expression; Mice; Models, Animal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Nitroprusside; Phenylephrine; Vasoconstriction | 2013 |
Aging impairs smooth muscle-mediated regulation of aortic stiffness: a defect in shock absorption function?
Topics: Adrenergic Agonists; Aging; Animals; Aorta; Enzyme Inhibitors; Focal Adhesions; Hemodynamics; Male; Mice; Mice, Inbred C57BL; Myocytes, Smooth Muscle; NG-Nitroarginine Methyl Ester; Phenylephrine; Pyrimidines; src-Family Kinases; Stress, Mechanical; Vascular Stiffness | 2014 |
Endogenous leptin contributes to baroreflex suppression within the solitary tract nucleus of aged rats.
Topics: Aging; Animals; Baroreflex; Hemodynamics; Insulin; Leptin; Male; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptors, Leptin; Reflex; Solitary Nucleus; Vasoconstrictor Agents | 2014 |
Characterizations of the α1-adrenoceptor subtypes mediating contractions of the human internal anal sphincter.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adult; Aged; Aged, 80 and over; Aging; Anal Canal; Fecal Incontinence; Female; Gene Expression; Humans; In Vitro Techniques; Isometric Contraction; Male; Mesenteric Artery, Inferior; Middle Aged; Muscle, Smooth; Phenylephrine; Receptors, Adrenergic, alpha-1; Risk | 2015 |
Adolescent vulnerability to cardiovascular consequences of chronic social stress: Immediate and long-term effects of social isolation during adolescence.
Topics: Aging; Animals; Baroreflex; Body Weight; Chronic Disease; Heart Rate; Male; Nitroprusside; Phenylephrine; Rats, Wistar; Social Isolation; Stress, Psychological; Time | 2016 |
Vascular endothelial function is improved by oral glycine treatment in aged rats.
Topics: Acetylcholine; Aging; Animals; Aorta; Cyclooxygenase 1; Cyclooxygenase 2; Endothelium, Vascular; Glycine; Humans; Indomethacin; Interleukin-1beta; Male; NADPH Oxidase 4; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrobenzenes; Phenylephrine; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides; Superoxide Dismutase; Superoxides; Tumor Necrosis Factor-alpha | 2015 |
Prostanoid-mediated contractions of the carotid artery become Nox2-independent with aging.
Topics: Acetylcholine; Aging; Animals; Antioxidants; Bridged Bicyclo Compounds, Heterocyclic; Carotid Arteries; Cyclic N-Oxides; Endothelium-Dependent Relaxing Factors; Fatty Acids, Unsaturated; Hydrazines; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; NADPH Oxidase 2; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Phenylephrine; Receptors, Thromboxane; RNA, Messenger; Spin Labels; Tissue Culture Techniques; Vasoconstrictor Agents; Vasodilator Agents | 2015 |
Diabetes and Age-Related Differences in Vascular Function of Renal Artery: Possible Involvement of Endoplasmic Reticulum Stress.
Topics: Acetylcholine; Aging; Animals; bcl-2-Associated X Protein; Biomarkers; Diabetes Mellitus, Type 2; Dinucleoside Phosphates; Endoplasmic Reticulum Stress; Endothelium, Vascular; Group IV Phospholipases A2; Male; Nitroprusside; Phenylephrine; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred OLETF; Renal Artery; Sirtuin 1; Taurochenodeoxycholic Acid; Vasodilation | 2016 |
Effects of 6 weeks oral administration of Phyllanthus acidus leaf water extract on the vascular functions of middle-aged male rats.
Topics: Acetylcholine; Administration, Oral; Aging; Animals; Aorta, Thoracic; Male; Mesenteric Arteries; Nitric Oxide Synthase Type III; Phenylephrine; Phyllanthus; Plant Extracts; Plant Leaves; Rats, Wistar; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents; Water | 2015 |
AKAP150 participates in calcineurin/NFAT activation during the down-regulation of voltage-gated K(+) currents in ventricular myocytes following myocardial infarction.
Topics: A Kinase Anchor Proteins; Aging; Animals; Animals, Newborn; Calcineurin; Cell Nucleus; Down-Regulation; Gene Expression Regulation; Heart Ventricles; Mice; Myocardial Infarction; Myocytes, Cardiac; NFATC Transcription Factors; Phenylephrine; Potassium Channels, Voltage-Gated; Protein Transport | 2016 |
Short-duration increases in intraluminal pressure improve vasoconstrictor responses in aged skeletal muscle feed arteries.
Topics: Aging; Amides; Angiotensin II; Animals; Arteries; Endothelium, Vascular; Male; Muscle, Skeletal; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Physical Conditioning, Animal; Pressure; Pyridines; Rats; Rats, Inbred F344; rho-Associated Kinases; Vasoconstriction; Vasoconstrictor Agents | 2016 |
Local renin-angiotensin system mediates endothelial dilator dysfunction in aging arteries.
Topics: Adrenergic alpha-1 Receptor Agonists; Aging; Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Arteries; Endothelium, Vascular; Enzyme Inhibitors; Fumarates; Indoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenylephrine; Rats; Rats, Inbred F344; Renin; Renin-Angiotensin System; Valsartan; Vasodilation | 2016 |
MicroRNA-203 mimics age-related aortic smooth muscle dysfunction of cytoskeletal pathways.
Topics: Aging; Animals; Aorta; Caveolin 1; Cells, Cultured; Cytoskeleton; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; MicroRNAs; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Paxillin; Phenylephrine; Promoter Regions, Genetic; Vascular Stiffness | 2017 |
Increased alpha1D adrenergic receptor activity and protein expression in the urinary bladder of aged rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aging; Animals; Blotting, Western; Fluorescent Antibody Technique; Phenylephrine; Piperazines; Prazosin; Rats; Rats, Inbred F344; Receptors, Adrenergic, alpha-1; Sympathetic Nervous System; Urinary Bladder | 2008 |
PKD1 haploinsufficiency is associated with altered vascular reactivity and abnormal calcium signaling in the mouse aorta.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Aging; Animals; Aorta; Calcium; Calcium Signaling; Cholinergic Agents; Endothelium; Gene Dosage; Hemodynamics; Humans; Kidney; Male; Mice; Muscle Tonus; Muscle, Smooth, Vascular; Phenylephrine; Polycystic Kidney, Autosomal Dominant; Transcription, Genetic; TRPP Cation Channels | 2009 |
Role of {alpha}1-adrenergic vasoconstriction in the regulation of skeletal muscle blood flow with advancing age.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Aging; Blood Flow Velocity; Exercise; Female; Humans; Infusions, Intra-Arterial; Lactic Acid; Laser-Doppler Flowmetry; Male; Muscle Contraction; Muscle, Skeletal; Oxygen Consumption; Phenylephrine; Propranolol; Receptors, Adrenergic, alpha-1; Regional Blood Flow; Vasoconstriction; Vasoconstrictor Agents; Young Adult | 2009 |
A comparison of pharmacologic and spontaneous baroreflex methods in aging and hypertension.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Aging; Amyl Nitrite; Baroreflex; Case-Control Studies; Female; Heart Rate; Humans; Hypertension; Injections, Intravenous; Male; Middle Aged; Phenylephrine; Valsalva Maneuver; Young Adult | 2009 |
The effects of propofol on vascular function in mesenteric arteries of the aging rat.
Topics: Acetylcholine; Aging; Animals; Antioxidants; Biological Factors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Hypnotics and Sedatives; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Phenylephrine; Propofol; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2009 |
Altered expression and alpha-1 adrenergic receptor mediated activity of protein kinase C in the prefrontal cortex of rats with neonatal ventral hippocampus lesions.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Aging; Animals; Animals, Newborn; Cell Membrane; Cytosol; Dose-Response Relationship, Drug; Hippocampus; Isoenzymes; Male; Phenylephrine; Phosphorylation; Prefrontal Cortex; Protein Kinase C; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1 | 2009 |
Baroreflex sensitivity is impaired in patients with obstructive jaundice.
Topics: Aged; Aging; Atrial Natriuretic Factor; Autonomic Nervous System; Baroreflex; Bilirubin; Body Temperature; Electrocardiography; Female; Hemodynamics; Humans; Jaundice, Obstructive; Male; Middle Aged; Nitroprusside; Phenylephrine; Vasoconstrictor Agents; Vasodilator Agents | 2009 |
Cyclooxygenase and thromboxane/prostaglandin receptor contribute to aortic endothelium-dependent dysfunction in aging female spontaneously hypertensive rats.
Topics: Acetylcholine; Age Factors; Aging; Animals; Aorta; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Fatty Acids, Unsaturated; Female; Hydrazines; Hypertension; Indomethacin; Male; Membrane Proteins; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Epoprostenol; Receptors, Thromboxane A2, Prostaglandin H2; Sex Factors; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2009 |
Aging and total stenosis triggers differential responses of carotid and basilar arteries to endothelin-1 and phenylephrine.
Topics: Aging; Animals; Basilar Artery; Carotid Arteries; Carotid Stenosis; Dose-Response Relationship, Drug; Endothelin-1; Guinea Pigs; Male; Phenylephrine; Potassium Chloride; Vasoconstriction; Vasoconstrictor Agents | 2009 |
ATP overflow in skeletal muscle 1A arterioles.
Topics: Action Potentials; Adenosine Triphosphate; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Age Factors; Aging; Anesthetics, Local; Animals; Arterioles; Biosensing Techniques; Electric Stimulation; Endothelium, Vascular; In Vitro Techniques; Muscle, Skeletal; Muscle, Smooth, Vascular; Phenylephrine; Prazosin; Rats; Rats, Inbred F344; Sympathetic Nervous System; Tetrodotoxin | 2010 |
Morphological and functional evidence for the contribution of the pudendal artery in aging-induced erectile dysfunction.
Topics: Acetylcholine; Aging; Animals; Apomorphine; Arteries; Dose-Response Relationship, Drug; Erectile Dysfunction; Male; Penile Erection; Penis; Phenylephrine; Rats; Rats, Sprague-Dawley | 2010 |
Severe phenylephrine-associated hemorrhage in five aged horses.
Topics: Adrenergic alpha-Agonists; Aging; Animals; Fatal Outcome; Hemorrhage; Horse Diseases; Horses; Phenylephrine | 2010 |
Structural modifications in the arterial wall during physiological aging and as a result of diabetes mellitus in a mouse model: are the changes comparable?
Topics: Acetylcholine; Aging; Animals; Aorta; Arteries; Diabetes Mellitus, Experimental; Endothelium, Vascular; Male; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Receptor for Advanced Glycation End Products; Receptors, Immunologic | 2011 |
Aging attenuates the vasodilator response to relaxin.
Topics: Aging; Animals; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Mesenteric Arteries; Models, Animal; Nitric Oxide; Phenylephrine; Rats; Rats, Wistar; Relaxin; Renal Artery; Vasoconstrictor Agents; Vasodilation | 2011 |
Age-related change in the effect of gentle mechanical cutaneous stimulation on the somato-cardiac sympathetic C-reflex.
Topics: Aging; Animals; Baroreflex; Blood Pressure; Electric Stimulation; Female; Heart; Naloxone; Phenylephrine; Physical Stimulation; Rats; Rats, Wistar; Reflex; Sympathetic Nervous System; Thigh; Tibial Nerve; Touch | 2011 |
Modulation of postjunctional α-adrenergic vasoconstriction during exercise and exogenous ATP infusions in ageing humans.
Topics: Adenosine; Adenosine Triphosphate; Adrenergic alpha-Agonists; Aged; Aging; Dexmedetomidine; Exercise; Female; Forearm; Hand Strength; Humans; Hyperemia; Male; Middle Aged; Muscle Contraction; Muscle, Skeletal; Phenylephrine; Ultrasonography, Doppler; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents; Young Adult | 2011 |
Spatiotemporally distinct protein kinase D activation in adult cardiomyocytes in response to phenylephrine and endothelin.
Topics: Aging; Animals; Cell Membrane; Endothelin-1; Enzyme Activation; Fluorescence Recovery After Photobleaching; Green Fluorescent Proteins; Histone Deacetylases; Models, Biological; Myocytes, Cardiac; Phenylephrine; Protein Binding; Protein Kinase C; Protein Transport; Rabbits; Recombinant Fusion Proteins; Sarcolemma; Signal Transduction; Time Factors | 2011 |
The effect of aging on adrenergic and nonadrenergic receptor expression and responsiveness in canine skeletal muscle.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Aging; Animals; Arteries; Blood Pressure; Clonidine; Dogs; Hemodynamics; Hindlimb; Muscle, Skeletal; Norepinephrine; Phenylephrine; Physical Conditioning, Animal; Purinergic P2X Receptor Agonists; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Neuropeptide Y; Receptors, Purinergic P2X; Regional Blood Flow; Rest | 2012 |
Tyrosine kinase receptor alteration of renal vasoconstriction in rats is sex- and age-related.
Topics: Aging; Animals; Arterioles; Enzyme Inhibitors; ErbB Receptors; Female; In Vitro Techniques; Male; Osmolar Concentration; Phenylephrine; Protein Kinase Inhibitors; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Receptor Protein-Tyrosine Kinases; Receptor, Insulin; Renal Circulation; Sex Characteristics; Vasoconstriction; Vasoconstrictor Agents | 2012 |
Western-style diet modulates contractile responses to phenylephrine differently in mesenteric arteries from senescence-accelerated prone (SAMP8) and resistant (SAMR1) mice.
Topics: Adrenergic alpha-1 Receptor Agonists; Aging; Animals; Cardiovascular Diseases; Diet, High-Fat; Female; Mesenteric Arteries; Mice; Myography; Oxidative Stress; Phenylephrine; Risk Factors; Vasoconstriction | 2013 |
Alterations by age of calcium handling in rat resistance arteries.
Topics: Aging; Animals; Caffeine; Calcium; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Phenylephrine; Rats; Rats, Sprague-Dawley; Vasoconstriction | 2002 |
Age-related changes in urethrovesical coordination in male rats: relationship with bladder instability?
Topics: Adrenergic Agents; Aging; Animals; Carbachol; Male; Muscle Contraction; Muscle, Smooth; Phenylephrine; Rats; Rats, Sprague-Dawley; Urethra; Urinary Bladder; Urinary Incontinence; Urination | 2003 |
Endothelium-dependent vasorelaxation and the expression of calcitonin gene-related peptide in aged rats.
Topics: Aging; Animals; Arginine; Calcitonin Gene-Related Peptide; Endothelium, Vascular; Gene Expression; Male; Phenylephrine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Vasoconstrictor Agents; Vasodilation | 2002 |
Proinflammatory cytokine inhibition of lacrimal gland secretion.
Topics: Aging; Animals; Female; In Vitro Techniques; Interleukin-1; Lacrimal Apparatus; Mice; Mice, Inbred BALB C; Mice, Inbred MRL lpr; Peroxidase; Phenylephrine; Potassium Chloride; Recombinant Proteins; Tumor Necrosis Factor-alpha; Up-Regulation | 2002 |
Differences in stimulus induced calcium increases in lacrimal gland acinar cells from normal and NZB/NZW F1 female mice.
Topics: Adrenergic alpha-Agonists; Aging; Animals; Calcium; Carbachol; Cholinergic Agonists; Electrophysiology; Female; Fura-2; In Vitro Techniques; Lacrimal Apparatus; Membrane Potentials; Mice; Mice, Inbred NZB; Patch-Clamp Techniques; Phenylephrine | 2002 |
Baroreflex buffering is reduced with age in healthy men.
Topics: Adult; Aged; Aging; Autonomic Nervous System; Baroreflex; Blood Pressure; Cardiovascular Physiological Phenomena; Ganglionic Blockers; Heart Rate; Humans; Male; Phenylephrine; Sympathetic Nervous System; Trimethaphan | 2003 |
Effects of aging on the arterial baroreflex control of muscle sympathetic nerve activity in healthy subjects.
Topics: Adolescent; Adult; Aging; Baroreflex; Blood Pressure; Carotid Sinus; Female; Heart Rate; Humans; Male; Middle Aged; Muscle, Skeletal; Nitroglycerin; Phenylephrine; Sympathetic Nervous System; Tibial Nerve; Vasoconstrictor Agents; Vasodilator Agents | 1994 |
Role of oxidative stress in age-related reduction of NO-cGMP-mediated vascular relaxation in SHR.
Topics: Aging; Animals; Aorta, Thoracic; Blood Pressure; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Hypertension; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Phenylephrine; Rats; Rats, Inbred SHR; Vasoconstrictor Agents; Vasodilation | 2003 |
THE EFFECT OF EXTERNAL COMPRESSION OF THE EYE ON INTRAOCULAR PRESSURE. II. RECOVERY: TONOGRAPHIC CHANGES AND THE INFLUENCE OF PHARMACOLOGIC AGENTS.
Topics: Acetazolamide; Aging; Atropa belladonna; Eye Diseases; Geriatrics; Humans; Intraocular Pressure; Manometry; Pharmacology; Phenylephrine; Physiology; Pilocarpine; Tonometry, Ocular | 1963 |
Chronic exercise improves myocardial inotropic reserve capacity through alpha1-adrenergic and protein kinase C-dependent effects in Senescent rats.
Topics: Aging; Alkaloids; Animals; Benzophenanthridines; Blotting, Western; Cardiotonic Agents; Citrate (si)-Synthase; Enzyme Inhibitors; In Vitro Techniques; Male; Mitogen-Activated Protein Kinase 3; Muscle, Skeletal; Myocardial Contraction; Phenanthridines; Phenylephrine; Physical Conditioning, Animal; Polymerase Chain Reaction; Protein Kinase C; Rats; Rats, Inbred F344; Receptors, Adrenergic, alpha-1; Signal Transduction; Ventricular Function, Left | 2004 |
Direct and indirect inhibition by catecholamines of hypocretin/orexin neurons.
Topics: Action Potentials; Adrenergic alpha-Agonists; Aging; Animals; Calcium Channels; Catecholamines; Clonidine; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Hypothalamus; Intracellular Signaling Peptides and Proteins; Membrane Potentials; Mice; Mice, Transgenic; Neural Inhibition; Neurons; Neuropeptides; Norepinephrine; Orexin Receptors; Orexins; Patch-Clamp Techniques; Phenylephrine; Potassium Channels, Inwardly Rectifying; Receptors, Adrenergic; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Tissue Culture Techniques | 2005 |
Effects of ovariectomy and growth hormone administration on body composition and vascular function and structure in old female rats.
Topics: Acetylcholine; Aging; Animals; Aorta, Thoracic; Body Composition; Dose-Response Relationship, Drug; Estrogens; Female; Human Growth Hormone; Ovariectomy; Phenylephrine; Postmenopause; Rats; Rats, Wistar; Recombinant Proteins; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2005 |
Impaired alpha1-adrenergic responses in aged rat hearts.
Topics: Adrenergic alpha-Agonists; Aging; Animals; Calcium Signaling; Cell Separation; Electric Stimulation; Heart; Imidazoles; Male; Myocytes, Cardiac; Organ Size; Phenylephrine; Protein Kinase C; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 2005 |
Enhanced role for RhoA-associated kinase in adrenergic-mediated vasoconstriction in gracilis arteries from obese Zucker rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic Agents; Aging; Amides; Animals; Arteries; Calcium Signaling; Gene Expression Regulation; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Muscle, Skeletal; Muscle, Smooth, Vascular; Obesity; Phenylephrine; Potassium Chloride; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Zucker; rho-Associated Kinases; rhoA GTP-Binding Protein; Thinness; Vasoconstriction | 2006 |
Ageing affects nitric oxide synthase, cyclooxygenase and oxidative stress enzymes expression differently in mesenteric resistance arteries.
Topics: Acetylcholine; Aging; Animals; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitrobenzenes; Oxidative Stress; Phenylephrine; Rats; Rats, Sprague-Dawley; Sulfonamides; Up-Regulation; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents | 2005 |
Angiotensin II activates matrix metalloproteinase type II and mimics age-associated carotid arterial remodeling in young rats.
Topics: Adrenergic alpha-Agonists; Aging; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Blotting, Western; Carotid Arteries; Collagen; Dipeptides; Immunohistochemistry; Losartan; Male; Matrix Metalloproteinase 2; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Organ Culture Techniques; Phenylephrine; Protease Inhibitors; Rats; RNA, Messenger; Transcription, Genetic; Transforming Growth Factor beta; Tunica Intima; Vasoconstrictor Agents | 2005 |
Knockdown of arginase I restores NO signaling in the vasculature of old rats.
Topics: Acetylcholine; Aging; Animals; Aorta; Arginase; Arginine; Calcium; Drug Synergism; Enzyme Inhibitors; In Vitro Techniques; Male; Nitric Oxide; Nitric Oxide Synthase; Oligonucleotides, Antisense; Oxadiazoles; Phenylephrine; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Up-Regulation; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2006 |
Effects of aging on Ca2+ signaling in murine mesenteric arterial smooth muscle cells.
Topics: Aging; Animals; Barium; Caffeine; Calcium; Calcium Channels; Calcium Channels, L-Type; Cell Membrane; Cell Physiological Phenomena; Cells, Cultured; Cytosol; Electrophysiology; Fura-2; Large-Conductance Calcium-Activated Potassium Channels; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Models, Statistical; Myocytes, Smooth Muscle; Patch-Clamp Techniques; Phenylephrine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Signal Transduction; Time Factors | 2006 |
Obesity-induced hypertension develops in young rats independently of the renin-angiotensin-aldosterone system.
Topics: Acetylcholine; Aging; Aldosterone; Animals; Blood Glucose; Cardiovascular System; Dietary Fats; Disease Models, Animal; Heart; Hypertension; Insulin; Intra-Abdominal Fat; Male; Obesity; Organ Size; Oxidative Stress; Phenylephrine; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Thiobarbituric Acid Reactive Substances; Vasoconstriction | 2006 |
Raloxifene prevents endothelial dysfunction in aging ovariectomized female rats.
Topics: Acetylcholine; Aging; Animals; Aorta, Thoracic; Bone Density Conservation Agents; Calcium Chloride; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Nitric Oxide; Nitric Oxide Synthase Type III; Ovariectomy; Phenylephrine; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2006 |
Normal aging impairs upregulation of the beta-adrenergic but not the alpha-adrenergic response: aging and adrenergic upregulation.
Topics: Adult; Aged; Aged, 80 and over; Aging; Blood Pressure; Clonidine; Female; Humans; Isoproterenol; Male; Middle Aged; Phenylephrine; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sex Characteristics; Up-Regulation | 2006 |
Effect of melatonin on vascular responses in aortic rings of aging rats.
Topics: Acetylcholine; Aging; Animals; Antioxidants; Aorta, Thoracic; Blood Glucose; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Lipid Peroxidation; Male; Melatonin; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Oxidative Stress; Phenylephrine; Rats; Rats, Wistar; Vasoconstrictor Agents; Vasodilator Agents | 2007 |
Vascular alpha1-adrenoceptors in isolated perfused rat kidney: influence of ageing.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Aging; Animals; In Vitro Techniques; Inhibitory Concentration 50; Kidney; Male; Norepinephrine; Perfusion; Phenylephrine; Piperazines; Rats; Rats, Inbred F344; Receptors, Adrenergic, alpha-1; Thymine; Vasoconstriction | 2007 |
Single dose treatment with PARP-inhibitor INO-1001 improves aging-associated cardiac and vascular dysfunction.
Topics: Acetylcholine; Aging; Animals; Enzyme Inhibitors; Heart; Immunohistochemistry; Indoles; Models, Animal; Myocardium; Phenylephrine; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Tyrosine | 2007 |
Exercise training fails to modify arterial baroreflex sensitivity in ovariectomized female rats.
Topics: Aging; Animals; Baroreflex; Blood Pressure; Bradycardia; Female; Heart Rate; Humans; Male; Menopause; Models, Animal; Nitroprusside; Ovariectomy; Ovary; Phenylephrine; Physical Conditioning, Animal; Rats; Rats, Inbred WKY; Tachycardia | 2007 |
Ageing and leg postjunctional alpha-adrenergic vasoconstrictor responsiveness in healthy men.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adult; Aged; Aging; Blood Flow Velocity; Dexmedetomidine; Dose-Response Relationship, Drug; Femoral Artery; Humans; Laser-Doppler Flowmetry; Leg; Male; Middle Aged; Norepinephrine; Phenylephrine; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Reference Values; Research Design; Sympathetic Nervous System; Tyramine; Vasoconstriction; Vasoconstrictor Agents | 2007 |
Ageing and vascular adrenoceptor desensitization: too little, too late?
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adult; Aged; Aging; Blood Flow Velocity; Dexmedetomidine; Femoral Artery; Humans; Leg; Male; Middle Aged; Norepinephrine; Phenylephrine; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Reference Values; Sympathetic Nervous System; Tyramine; Vasoconstriction; Vasoconstrictor Agents | 2007 |
Impairment of sympathetic baroreceptor reflexes in obese Zucker rats.
Topics: Aging; Animals; Baroreflex; Blood Pressure; Disease Models, Animal; Heart; Heart Rate; Hypertension; Male; Nitroprusside; Obesity; Phenylephrine; Rats; Rats, Zucker; Splanchnic Nerves; Sympathetic Nervous System; Vasoconstrictor Agents; Vasodilator Agents; Vasomotor System | 2007 |
The senescence-accelerated mouse (SAM-P8) as a model for the study of vascular functional alterations during aging.
Topics: Acetylcholine; Aging; Animals; Aorta, Thoracic; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Indomethacin; Lipid Peroxidation; Male; Malondialdehyde; Mice; Mice, Inbred Strains; Models, Animal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phenylephrine; Potassium Chloride; Prostaglandin-Endoperoxide Synthases; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2007 |
Effects of aging on adipose resistance artery vasoconstriction: possible implications for orthostatic blood pressure regulation.
Topics: Adaptation, Physiological; Adipose Tissue, White; Age Factors; Aging; Animals; Arteries; Blood Flow Velocity; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rate; Hypotension, Orthostatic; In Vitro Techniques; Male; Norepinephrine; Phenylephrine; Posture; Rats; Rats, Inbred F344; Regional Blood Flow; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents | 2007 |
Gene expression changes of prostanoid synthases in endothelial cells and prostanoid receptors in vascular smooth muscle cells caused by aging and hypertension.
Topics: Acetylcholine; Aging; Animals; Aorta, Thoracic; Cyclooxygenase 1; Endothelial Cells; Enzyme Induction; Gene Expression Profiling; Gene Expression Regulation; Hypertension; Membrane Proteins; Muscle Proteins; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phenylephrine; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Prostaglandin | 2008 |
Low-dose aspirin prevents age-related endothelial dysfunction in a mouse model of physiological aging.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcholine; Age Factors; Aging; Animals; Antioxidants; Aorta; Aspirin; Cardiovascular Diseases; Deoxyguanosine; Dose-Response Relationship, Drug; Endothelium, Vascular; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Models, Animal; Oxidative Stress; Phenylephrine; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2008 |
Aging increases cytochrome P450 4A modulation of alpha1-adrenergic vasoconstriction in mesenteric arteries.
Topics: Adrenergic alpha-Agonists; Aging; Amides; Animals; Cytochrome P-450 CYP4A; Endothelin-1; Hydroxyeicosatetraenoic Acids; Male; Mesenteric Arteries; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Sulfones; Vasoconstriction | 2008 |
Region and age dependent differences in alpha(1)-adrenergic responsiveness of rat seminal vesicle and vas deferens.
Topics: Adrenergic alpha-Agonists; Aging; Animals; Body Weight; Data Interpretation, Statistical; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Phenylephrine; Potassium Chloride; Radioligand Assay; Rats; Rats, Inbred F344; Receptors, Adrenergic, alpha-1; Reverse Transcriptase Polymerase Chain Reaction; Seminal Vesicles; Testosterone; Vas Deferens | 2008 |
Low-intensity voluntary running lowers blood pressure with simultaneous improvement in endothelium-dependent vasodilatation and insulin sensitivity in aged spontaneously hypertensive rats.
Topics: Acetylcholine; Aging; Animals; Aorta, Thoracic; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Hypertension; Insulin Resistance; Male; Nitroprusside; Phenylephrine; Physical Conditioning, Animal; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2008 |
Adrenergic and cholinergic mediated glucose oxidation by rat parotid gland acinar cells during aging.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aging; Animals; Carbachol; Cell Aggregation; Epinephrine; Glucose; Glycolysis; Isoproterenol; Male; Parotid Gland; Phenylephrine; Rats | 1981 |
Age-associated increments in human platelet alpha-adrenoceptor capacity. Possible mechanism for platelet hyperactivity to epinephrine in aging man.
Topics: Adult; Aged; Aging; Binding, Competitive; Blood Platelets; Dihydroergotoxine; Drug Hypersensitivity; Epinephrine; Female; Humans; Male; Middle Aged; Phentolamine; Phenylephrine; Platelet Aggregation; Radioligand Assay; Receptors, Adrenergic, alpha | 1984 |
Acute shallowing of the anterior chamber.
Topics: Acetazolamide; Aged; Aging; Anterior Chamber; Glaucoma; Humans; Intraocular Pressure; Iris; Middle Aged; Moxisylyte; Phenylephrine; Pilocarpine; Procaine | 1981 |
Age-related changes in sensitivity of rat urinary bladder to autonomic agents.
Topics: Acetylcholine; Aging; Animals; Autonomic Agents; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Phenylephrine; Rats; Rats, Inbred F344; Receptors, Muscarinic; Urinary Bladder | 1984 |
Evidence for a neuropathic aetiology in the small pupil of diabetes mellitus.
Topics: Adolescent; Adult; Aging; Darkness; Diabetic Neuropathies; Humans; Iris; Middle Aged; p-Hydroxyamphetamine; Phenylephrine; Pupil; Sympathetic Nervous System | 1983 |
The influences of glucagon, epinephrine and adrenergic agents on glycogen phosphorylase a and pyruvate kinase activities in hepatocytes from juvenile and adult rabbits.
Topics: Aging; Animals; Epinephrine; Glucagon; Isoproterenol; Liver; Male; Phentolamine; Phenylephrine; Phosphorylase a; Phosphorylases; Propranolol; Pyruvate Kinase; Rabbits; Sympathomimetics | 1982 |
Normal excretion of m-hydroxymandelic acid in hypertensive patients.
Topics: Adolescent; Adult; Aged; Aging; Diastole; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydroxy Acids; Hypertension; Male; Mandelic Acids; Middle Aged; Phenylephrine; Sex Factors; Systole | 1981 |
H1- and H2-histamine receptor-mediated vasodilation varies with aging in humans.
Topics: Adult; Aged; Aged, 80 and over; Aging; Cimetidine; Dose-Response Relationship, Drug; Female; Hand; Histamine; Humans; Male; Middle Aged; Phenylephrine; Receptors, Histamine H1; Receptors, Histamine H2; Vasodilation; Vasodilator Agents | 1995 |
Sustained negative inotropism mediated by alpha-adrenoceptors in adult mouse myocardia: developmental conversion from positive response in the neonate.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aging; Animals; Animals, Newborn; Atropine; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Heart; In Vitro Techniques; Mice; Myocardial Contraction; Myocardium; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Propranolol; Receptors, Adrenergic, alpha; Yohimbine | 1995 |
Differential expression of TnI and TnT isoforms in rabbit heart during the perinatal period and during cardiovascular stress.
Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Embryonic and Fetal Development; Female; Gene Expression; Gestational Age; Heart; Heart Ventricles; Maternal-Fetal Exchange; Myocardial Contraction; Myocardium; Phenylephrine; Pregnancy; Rabbits; Troponin; Troponin I; Troponin T | 1995 |
Aging and vasoreactivity: in vivo responses in the beagle hindlimb.
Topics: Acetylcholine; Aging; Albuterol; Animals; Aorta; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Female; Femoral Artery; Hindlimb; Ischemia; Muscle, Smooth, Vascular; Muscles; Norepinephrine; Phenylephrine; Regional Blood Flow; Renin; Vascular Resistance; Vasoconstriction; Vasodilation | 1995 |
Cardiopulmonary and arterial baroreflex responses to acute volume expansion during fetal and postnatal development.
Topics: Aging; Animals; Animals, Newborn; Baroreflex; Blood Pressure; Blood Volume; Embryonic and Fetal Development; Female; Fetus; Gestational Age; Heart Rate; Kidney; Phenylephrine; Pregnancy; Pulmonary Circulation; Renal Circulation; Sheep; Sympathetic Nervous System | 1994 |
Ontogenic changes in renal response to alpha 1-adrenoceptor stimulation in sheep.
Topics: Aging; Animals; Animals, Newborn; Blood Pressure; Chlorides; Dose-Response Relationship, Drug; Embryonic and Fetal Development; Female; Gestational Age; Glomerular Filtration Rate; Heart Rate; Heart Rate, Fetal; Infusions, Intravenous; Kidney; Norepinephrine; Phenylephrine; Pregnancy; Receptors, Adrenergic, alpha-1; Reference Values; Renal Circulation; Sheep; Sodium; Urine; Vasoconstriction | 1994 |
Age-related changes in release of endothelium-derived relaxing factor from the carotid artery.
Topics: Acetylcholine; Aging; Animals; Aorta, Thoracic; Biological Assay; Blood Pressure; Carotid Artery, Common; Endothelium, Vascular; Image Processing, Computer-Assisted; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Phenylephrine; Rats; Rats, Wistar; Vasoconstriction; Vasodilation | 1994 |
Thromboxane A2-prostaglandin H2 and renovascular hypertension in rats.
Topics: Aging; Angiotensin II; Animals; Arginine Vasopressin; Baroreflex; Blood Pressure; Body Weight; Caprylates; Cyclooxygenase Inhibitors; Diastole; Furosemide; Heart; Heart Conduction System; Heart Rate; Heart Ventricles; Hypertension, Renovascular; Kidney; Male; Nitroprusside; Norepinephrine; Organ Size; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane; Reference Values; Sulfonamides; Systole; Time Factors; Vasoconstriction | 1994 |
Dietary Na and baroreflex modulation of blood pressure and RSNA in normotensive vs. spontaneously hypertensive rats.
Topics: Aging; Animals; Baroreflex; Blood Pressure; Body Weight; Carotid Arteries; Denervation; Femoral Vein; Heart Rate; Kidney; Male; Muscle, Smooth, Vascular; Nitroprusside; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sinoatrial Node; Sodium, Dietary; Sympathetic Nervous System | 1994 |
Age-dependent changes of baroreflex efficiency in Dahl rats: effects of high salt intake.
Topics: Aging; Animals; Baroreflex; Blood Pressure; Heart Rate; Male; Phenylephrine; Rats; Rats, Inbred Strains; Sodium Chloride | 1993 |
Age-dependent changes of baroreflex efficiency in Dahl rats: effects of high salt intake.
Topics: Aging; Animals; Baroreflex; Blood Pressure; Genotype; Heart Rate; Male; Phenylephrine; Rats; Rats, Inbred Strains; Sodium, Dietary | 1993 |
Age related changes in contractility and alpha 1 adrenergic responsiveness of myocardium from normal hamsters and hamsters with hereditary cardiomyopathy.
Topics: Aging; Animals; Cardiomyopathies; Cricetinae; Dose-Response Relationship, Drug; Male; Mesocricetus; Myocardial Contraction; Phenylephrine; Receptors, Adrenergic, alpha; Temperature | 1993 |
Nitrate tolerance and aging in isolated rat aorta.
Topics: Aging; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Drug Tolerance; In Vitro Techniques; Male; Molsidomine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Phenylephrine; Rats; Rats, Wistar; Vasodilator Agents | 1993 |
Changes in alpha 1-adrenoceptor coupling to Ca2+ channels during development in rat heart.
Topics: Aging; Animals; Animals, Newborn; Calcium Channels; Electric Conductivity; Heart; Membrane Potentials; Phenylephrine; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Ventricular Function | 1994 |
Long-term caloric restriction improves baroreflex sensitivity in aging Fischer 344 rats.
Topics: Aging; Animals; Blood Pressure; Energy Intake; Heart Rate; Male; Nitroprusside; Phenylephrine; Rats; Rats, Inbred F344; Reflex | 1993 |
Age-dependent overflow of endogenous norepinephrine from paraventricular hypothalamic nucleus of hypertensive rats.
Topics: Aging; Animals; Blood Pressure; Hypertension; Male; Nitroprusside; Norepinephrine; Paraventricular Hypothalamic Nucleus; Phenylephrine; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley | 1993 |
Effects of age and indomethacin on response and sensitivity of pulmonary artery to phenylephrine and to histamine in pigs.
Topics: Aging; Animals; Arachidonic Acid; Dogs; Dose-Response Relationship, Drug; Female; Histamine; Indomethacin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Pulmonary Artery; Vasoconstriction | 1993 |
Augmented neuronal activity in the hypothalamus of spontaneously hypertensive rats.
Topics: Aging; Animals; Blood Pressure; Electrophysiology; Hypothalamus; Hypothalamus, Posterior; In Vitro Techniques; Neurons; Phenylephrine; Pressoreceptors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Stereotaxic Techniques | 1993 |
Age-related reduction of reflex bradycardia in conscious rats by catecholaminergic nucleus tractus solitarius lesions.
Topics: Aging; Animals; Blood Pressure; Bradycardia; Heart Rate; Male; Medulla Oblongata; Nitroprusside; Oxidopamine; Phenylephrine; Rats; Reflex; Weight Loss | 1993 |
Maturation of kitten ventral medullary surface activity during pressor challenges.
Topics: Aging; Animals; Blood Gas Analysis; Blood Pressure; Cardiotonic Agents; Cats; Diaphragm; Dose-Response Relationship, Drug; Electrocardiography; Electromyography; Electrophysiology; Heart Rate; Image Processing, Computer-Assisted; Medulla Oblongata; Phenylephrine; Pressoreceptors; Respiratory Mechanics; Tidal Volume | 1995 |
Reactivity to alpha agonists is heightened in immature porcine pulmonary arteries.
Topics: Adrenergic alpha-Agonists; Aging; Animals; Endothelium, Vascular; Humans; Hypertension, Pulmonary; Muscle, Smooth; Phenylephrine; Pulmonary Artery; Swine; Vasoconstriction | 1996 |
A role of asialoglycoproteins for plasma-membrane-induced inhibition of the switching from alpha 1 to beta subtypes in adrenergic response during primary culture of rat hepatocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aging; Animals; Asialoglycoproteins; beta-Galactosidase; Cell Division; Cell Membrane; Cells, Cultured; Cyclic AMP; Glucagon; Glycoside Hydrolases; Inositol 1,4,5-Trisphosphate; Isoproterenol; Kinetics; Liver; Membrane Glycoproteins; Neuraminidase; Phenylephrine; Rats; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta | 1996 |
Altered in vivo catecholamine release in the hypothalamic paraventricular nucleus of the aged rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Catecholamines; Homovanillic Acid; Male; Norepinephrine; Paraventricular Hypothalamic Nucleus; Phenylephrine; Rats; Rats, Sprague-Dawley | 1996 |
Alterations in the cardiovascular control by the chemoreflex and the baroreflex in old rats.
Topics: Aging; Animals; Baroreflex; Blood Pressure; Cardiovascular Physiological Phenomena; Chemoreceptor Cells; Dose-Response Relationship, Drug; Heart Rate; Injections, Intravenous; Nitroprusside; Phenylephrine; Potassium Cyanide; Rats; Rats, Wistar; Reflex | 1996 |
Hypotensive and reflex bradycardic effects of ketanserin, but not of prazosin, enhanced selectively in aging conscious rats.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Aging; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Heart Rate; Injections, Intravenous; Ketanserin; Male; Nitroprusside; Phenylephrine; Prazosin; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Vasoconstrictor Agents | 1996 |
[Effect of aging on alpha-1 receptor-mediated, phenylephrine-induced contraction and pressor response: relationship with the amount of receptors].
Topics: Adrenergic alpha-Agonists; Aging; Animals; Aorta, Thoracic; Blood Pressure; Male; Phenylephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Vasoconstriction | 1995 |
Age-related changes in alpha-adrenoceptor-mediated blood pressure in the rat: relationship between the potency for phenylephrine and the maximum number of binding sites.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aging; Analysis of Variance; Animals; Aorta, Thoracic; Binding Sites; Blood Pressure; Cell Survival; Decerebrate State; Dose-Response Relationship, Drug; Femoral Artery; Isotope Labeling; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Prazosin; Rats; Rats, Wistar; Regional Blood Flow | 1996 |
Age-dependent changes in cardiac muscarinic receptor function in healthy volunteers.
Topics: Adult; Aging; Atropine; Baroreflex; Blood Pressure; Heart; Heart Rate; Humans; Male; Middle Aged; Muscarinic Antagonists; Myocardium; Phenylephrine; Pirenzepine; Pressoreceptors; Receptors, Muscarinic | 1997 |
Prostaglandin F2 alpha induces cardiac myocyte hypertrophy in vitro and cardiac growth in vivo.
Topics: Aging; Animals; Animals, Newborn; Atrial Natriuretic Factor; Cardiomegaly; Cells, Cultured; Dinoprost; Heart; Male; Myocardial Infarction; Myocardium; Phenylephrine; Prostaglandins; Prostaglandins F, Synthetic; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors | 1996 |
Impairment of vascular function is associated with an age-related increase of lipid peroxidation in rats.
Topics: Aging; Animals; Arteries; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Fatty Acids, Unsaturated; Female; Hydrazines; Lipid Peroxides; Meclofenamic Acid; Methacholine Chloride; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 1996 |
Evidence for an age-dependent functional expression of alpha 1D-adrenoceptors in the rat vasculature.
Topics: Adrenergic alpha-Antagonists; Aging; Animals; Blood Pressure; Blood Vessels; Clonidine; Male; Phenylephrine; Piperazines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 1997 |
Effect of aging on norepinephrine and phenylephrine stimulated lactate production by white adipocytes.
Topics: Adipocytes; Aging; Analysis of Variance; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Glucose; Glycerol; Lactates; Lipolysis; Male; Neurotransmitter Agents; Norepinephrine; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Vasoconstrictor Agents | 1997 |
Exercise training enhances cardiac function in response to an afterload stress in older men.
Topics: Aged; Aging; Blood Pressure; Body Composition; Cardiotonic Agents; Coronary Circulation; Echocardiography; Exercise; Heart; Heart Rate; Humans; Male; Middle Aged; Muscarinic Antagonists; Myocardium; Phenylephrine; Physical Education and Training; Physical Endurance; Physical Fitness; Ventricular Function, Left | 1997 |
Postnatal changes in mechanisms mediating acetylcholine-induced relaxation in piglet femoral arteries.
Topics: Aging; Aminoquinolines; Animals; Animals, Newborn; Endothelium, Vascular; Enzyme Inhibitors; Femoral Artery; Guanylate Cyclase; In Vitro Techniques; Indomethacin; Male; Muscle Development; Muscle, Smooth, Vascular; Nitroprusside; omega-N-Methylarginine; Phenylephrine; Potassium Chloride; Swine; Vasodilation | 1997 |
Desensitization of alpha 1-, beta- and glucagon receptors in rat hepatocytes: influence of ageing.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aging; Animals; Centrifugation, Density Gradient; Glucagon; Glycogen; Isoproterenol; Liver; Male; Phenylephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Glucagon | 1994 |
Age dependence of the development of ventricular arrhythmias in a canine model of sudden cardiac death.
Topics: Aging; Animals; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Dog Diseases; Dogs; Electrocardiography, Ambulatory; Epinephrine; Heart; Heart Rate; Incidence; Phenylephrine; Risk Factors; Sympathomimetics | 1997 |
Age-related changes in the reactivity of postsynaptic adrenoceptors in the rat vas deferens: differences between the epididymal and prostatic portion.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aging; Animals; Epididymis; Epinephrine; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Phenylephrine; Prostate; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Vas Deferens | 1997 |
Short-term lisinopril treatment in old rats worsens impairment of angiotensin-induced reflex bradycardia.
Topics: Aging; Angiotensin II; Animals; Antihypertensive Agents; Bradycardia; Lisinopril; Male; Phenylephrine; Rats; Rats, Sprague-Dawley | 1997 |
Does chronic ketanserin treatment enhance bradycardia in old rats by serotonergic blockade?
Topics: Adrenergic alpha-Agonists; Aging; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Bradycardia; Heart Rate; Ketanserin; Male; Phenylephrine; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Tachycardia | 1998 |
Maturation and aging-related differences in responsiveness of rat aorta and carotid arteries to alpha1-adrenoceptor stimulation.
Topics: Adrenergic alpha-Antagonists; Aging; Analysis of Variance; Animals; Aorta, Thoracic; Carotid Arteries; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Drug Interactions; Male; Muscle, Smooth, Vascular; Phenylephrine; Potassium Chloride; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Vasoconstrictor Agents | 1998 |
Factors involved in the effects of losartan on endothelial dysfunction induced by aging in SHR.
Topics: Acetylcholine; Aging; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Kidney; Losartan; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitrites; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Vasoconstrictor Agents; Vasodilation | 1998 |
Effects of age and gender on cardiovascular responses to phenylephrine.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Aging; Atropine; Blood Pressure; Cardiac Output; Diastole; Echocardiography; Female; Heart; Heart Rate; Heart Ventricles; Humans; Male; Middle Aged; Muscarinic Antagonists; Myocardial Contraction; Phenylephrine; Physical Exertion; Sex Factors; Sympathetic Nervous System; Systole; Vagus Nerve; Ventricular Function, Left | 1999 |
Effects of age and hypertension on cardiac responses to the alpha1-agonist phenylephrine in humans.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Aging; Atropine; Baroreflex; Echocardiography; Electrocardiography; Female; Follow-Up Studies; Heart Ventricles; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Parasympatholytics; Phenylephrine; Receptors, Adrenergic, alpha; Vagus Nerve | 1999 |
Impaired cholera toxin relaxation with age in rat aorta.
Topics: Adenosine Diphosphate; Adrenergic beta-Agonists; Aging; Animals; Aorta, Thoracic; Cholera Toxin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; GTP-Binding Proteins; Isoproterenol; Male; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred F344; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
Abated cardiovascular responses to chronic oral lisinopril treatment in conscious elderly rats.
Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Baroreflex; Blood Pressure; Body Weight; Bradycardia; Consciousness; Drinking; Lisinopril; Male; Norepinephrine; Phenylephrine; Rats; Rats, Sprague-Dawley; Sympathomimetics; Vasoconstrictor Agents | 1999 |
Functional evidence of alpha1D-adrenoceptors in the vasculature of young and adult spontaneously hypertensive rats.
Topics: Aging; Animals; Blood Pressure; Hypertension; Male; Phenylephrine; Piperazines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha-1 | 1999 |
Human sympathetic and vagal baroreflex responses to sequential nitroprusside and phenylephrine.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Baroreflex; Blood Pressure; Female; Humans; Male; Middle Aged; Nitroprusside; Phenylephrine; Retrospective Studies; Sympathetic Nervous System; Vagus Nerve; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
Age-related change of the role of alpha1L-adrenoceptor in canine urethral smooth muscle.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Aging; Animals; Autoradiography; Binding, Competitive; Cresols; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Parity; Phentolamine; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha-1; Sulfonamides; Tamsulosin; Urethra; Vasoconstrictor Agents | 1999 |
Vascular wall dysfunction in JCR:LA-cp rats: effects of age and insulin resistance.
Topics: Acetylcholine; Aging; Animals; Arteriosclerosis; Blood Glucose; Body Weight; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Eicosanoids; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Insulin; Insulin Resistance; Male; Meclofenamic Acid; Mesenteric Arteries; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Norepinephrine; Obesity; Phenylephrine; Rats; Rats, Mutant Strains; Triglycerides; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
Subtype specific regulation of human vascular alpha(1)-adrenergic receptors by vessel bed and age.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Aged; Aging; Aorta; Arteries; Celiac Artery; Dopamine Antagonists; Female; Femoral Artery; Gene Expression; Hepatic Artery; Humans; Iliac Artery; In Vitro Techniques; Male; Mammary Arteries; Middle Aged; Phenylephrine; Piperazines; Prazosin; Radioligand Assay; Receptors, Adrenergic, alpha-1; Renal Artery; RNA, Messenger; Saphenous Vein; Spiperone; Splenic Artery; Vasoconstriction | 1999 |
The role of alpha 1L-adrenoceptor in rat urinary bladder: comparison between young adult and aged rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aging; Animals; Cresols; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Phenylephrine; Prazosin; Radionuclide Imaging; Rats; Rats, Inbred F344; Receptors, Adrenergic, alpha-1; Urinary Bladder | 1999 |
Functional and morphological modifications of the urinary bladder in aging female rats.
Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aging; Animals; Arecoline; Carbachol; Cholinergic Agonists; Consciousness; Female; Isoproterenol; Muscle Contraction; Muscle, Smooth; Norepinephrine; Organ Size; Phenylephrine; Potassium Chloride; Rats; Rats, Wistar; Urinary Bladder; Urodynamics | 2000 |
Sympathetic and reflex alterations in systo-diastolic and systolic hypertension of the elderly.
Topics: Adult; Aged; Aging; Baroreflex; Blood Pressure; Case-Control Studies; Diastole; Female; Humans; Hypertension; Male; Middle Aged; Nitroprusside; Phenylephrine; Pressoreceptors; Sympathetic Nervous System; Systole | 2000 |
Age-related involvement of the endothelium in beta-adrenoceptor-mediated relaxation of rat aorta.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Aorta, Thoracic; Apamin; Atenolol; Charybdotoxin; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Isoproterenol; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Peptides; Phenylephrine; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Vasoconstriction; Vasodilation | 2000 |
Contractile properties of urethral smooth muscles of young and aged female dogs: morphological and pharmacological aspects.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aging; Animals; Autoradiography; Dogs; Female; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenylephrine; Prazosin; Sulfonamides; Tamsulosin; Urethra | 2000 |
Aging and baroreflex control of RSNA and heart rate in rats.
Topics: Aging; Animals; Baroreflex; Blood Pressure; Heart Rate; Kidney; Nitroprusside; Phenylephrine; Rats; Rats, Wistar; Sympathetic Nervous System; Sympathomimetics; Systole; Vagus Nerve | 2000 |
Aging exacerbates hydrogen peroxide-induced alteration of vascular reactivity in rats.
Topics: Acetylcholine; Age Factors; Aging; Animals; Aorta; Catalase; Dose-Response Relationship, Drug; Endothelium, Vascular; Hydrogen Peroxide; Male; Phenylephrine; Rats; Rats, Wistar; Reactive Oxygen Species; Time Factors | 2000 |
Paradoxically enhanced endothelin-B receptor-mediated vasoconstriction in conscious old monkeys.
Topics: Aging; Angiotensin II; Animals; Consciousness; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Macaca fascicularis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptides, Cyclic; Phenylephrine; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Vasoconstriction; Vasoconstrictor Agents; Viper Venoms | 2001 |
Altered autonomic support of arterial blood pressure with age in healthy men.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Aging; Autonomic Nervous System; Blood Pressure; Cardiac Output; Cardiovascular Diseases; Ganglia, Autonomic; Ganglionic Blockers; Heart; Heart Rate; Humans; Men; Phenylephrine; Trimethaphan | 2001 |
Coronary and aortic vasoreactivity protection with endothelin receptor antagonist, bosentan, after ischemia and hypoxia in aged rats.
Topics: Acetylcholine; Aging; Animals; Aorta, Thoracic; Bosentan; Coronary Circulation; Coronary Vessels; Endothelin Receptor Antagonists; Hypoxia; In Vitro Techniques; Male; Myocardial Ischemia; Nitroprusside; Oxygen; Phenylephrine; Rats; Rats, Wistar; Reperfusion Injury; Sulfonamides; Time Factors; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2001 |
Aortic vasoreactivity during prolonged hypoxia and hypoxia-reoxygenation in senescent rats.
Topics: Acetylcholine; Aging; Animals; Aorta; Hypoxia; Male; Nitroprusside; Oxygen; Phenylephrine; Rats; Rats, Wistar; Vasoconstrictor Agents; Vasodilator Agents | 2002 |
Reduction in sarcoplasmic reticulum Ca2+-ATPase activity contributes to age-related changes in the calcium content and relaxation rate of rabbit aortic smooth muscle.
Topics: Aging; Animals; Aorta, Thoracic; Calcium-Transporting ATPases; Electron Probe Microanalysis; Enzyme Inhibitors; Female; Male; Models, Animal; Models, Cardiovascular; Muscle, Smooth, Vascular; Myocardial Contraction; Observer Variation; Phenylephrine; Potassium Channels; Rabbits; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thapsigargin; Time Factors; Vasoconstrictor Agents | 1996 |
Alpha- and beta-adrenergic mechanisms in the aorta of newborn rabbits and guinea-pigs.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; Aorta; Female; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; Nitrites; Phentolamine; Phenylephrine; Rabbits; Serotonin | 1979 |
Biochemical aspects of cardiac muscle differentiation. Possible control of deoxyribonucleic acid synthesis and cell differentiation by adrenergic innervation and cyclic adenosine 3':5'-monophosphate.
Topics: Aging; Animals; Animals, Newborn; Bucladesine; Cell Differentiation; Cyclic AMP; Cyclic GMP; DNA Replication; Heart; Isoproterenol; Muscle Proteins; Muscle, Smooth; Myocardium; Myosins; Norepinephrine; Phenylephrine; Protein Biosynthesis; Rats; Theophylline | 1976 |
Postnatal development of adrenergic and cholinergic sensitivity in the isolated rat atria.
Topics: Acetylcholine; Aging; Animals; Carbachol; Heart; Heart Atria; Isoproterenol; Male; Norepinephrine; Parasympathomimetics; Phenylephrine; Rats; Sympathomimetics | 1977 |
Age-associated decrease in ventricular response to haemodynamic stress during beta-adrenergic blockade.
Topics: Adolescent; Adult; Aged; Aging; Blood Pressure; Heart; Heart Ventricles; Humans; Isometric Contraction; Middle Aged; Myocardial Contraction; Phenylephrine; Propranolol; Ventricular Function | 1978 |
A low-sodium diet corrects the defect in beta-adrenergic response in older subjects.
Topics: Adenylyl Cyclases; Aged; Aging; Blood Pressure; Blood Vessels; Diet, Sodium-Restricted; Electrolytes; Female; Humans; Lymphocytes; Male; Middle Aged; Nitroglycerin; Norepinephrine; Phenylephrine; Receptors, Adrenergic, beta; Reference Values; Up-Regulation; Vasoconstriction; Vasodilation | 1992 |
Age-related delay in recovery of beta-adrenergic sensitivity after abrupt propranolol withdrawal in rats.
Topics: Aging; Animals; Blood Pressure; Drug Resistance; Epinephrine; Heart Rate; Male; Phenylephrine; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1992 |
Vascular beta-adrenoceptor-mediated responses in hypertension and ageing in rats.
Topics: Aging; Animals; Aorta, Thoracic; Blood Pressure; Hypertension; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Vasoconstriction; Vasodilation | 1992 |
Age-dependent changes in alpha-adrenoceptor-mediated contractility of isolated human resistance arteries.
Topics: Adrenergic alpha-Agonists; Aging; Arteries; Azepines; Blood Pressure; Electric Stimulation; Humans; In Vitro Techniques; Nervous System Physiological Phenomena; Phenylephrine; Receptors, Adrenergic, alpha; Vascular Resistance; Vasoconstriction | 1992 |
Dietary sodium and the antihypertensive effect of nifedipine in spontaneously hypertensive rats.
Topics: Aging; Animals; Antihypertensive Agents; Blood Pressure; Heart Rate; Heart Ventricles; Hemodynamics; Hexamethonium Compounds; Hypertension; Male; Nifedipine; Organ Size; Phenylephrine; Rats; Rats, Inbred SHR; Sodium, Dietary; Sympathetic Nervous System | 1992 |
[Influences of hypercholesterolemia on the vessel function of isolated rat thoracic aorta].
Topics: Acetylcholine; Aging; Animals; Aorta, Thoracic; Arginine; Body Weight; Cholesterol, Dietary; Endothelium, Vascular; Hypercholesterolemia; In Vitro Techniques; Male; Muscle, Smooth, Vascular; omega-N-Methylarginine; Phenylephrine; Piperidines; Pyrimidinones; Rats; Rats, Inbred Strains; Vasoconstriction | 1992 |
Bradykinin-induced venodilation is not impaired with aging in humans.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Bradykinin; Dose-Response Relationship, Drug; Female; Hand; Humans; Infusions, Intravenous; Isoproterenol; Male; Middle Aged; Nitric Oxide; Phenylephrine; Vasoconstriction; Vasodilation; Veins | 1992 |
Alterations in the secretion of atrial natriuretic factor in atria from aged rats.
Topics: Aging; Animals; Atrial Natriuretic Factor; Heart Atria; Myocardium; Phenylephrine; Physical Stimulation; Rats; Rats, Inbred F344 | 1992 |
Functional responses of hindlimb circulation in aged normal and WHHL rabbits.
Topics: Acetylcholine; Aging; Animals; Arteriosclerosis; Bradykinin; Endothelium, Vascular; Hindlimb; Hyperlipidemias; Nitroprusside; Phenylephrine; Rabbits; Regional Blood Flow; Serotonin; Vascular Resistance | 1992 |
Effects of the selective serotonin reuptake inhibitor fluoxetine on baroreceptor reflex sensitivity and body weight in young and old rats.
Topics: Aging; Animals; Blood Pressure; Body Weight; Fluoxetine; Heart Rate; Male; Nitroglycerin; Phenylephrine; Pressoreceptors; Rats; Reflex | 1992 |
Differential effects of aging on the heart rate and blood pressure influences of arterial baroreceptors in awake rats.
Topics: Aging; Animals; Aorta; Arteries; Blood Pressure; Carotid Arteries; Constriction, Pathologic; Denervation; Heart Rate; Nitroprusside; Oxygen; Phenylephrine; Pressoreceptors; Rats; Rats, Inbred Strains | 1991 |
Age-dependent alterations in the efficacy of phenylephrine-induced contractions in vascular smooth muscle isolated from the corpus cavernosum of impotent men.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Aging; Diabetes Complications; Diabetes Mellitus; Erectile Dysfunction; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Penis; Phenylephrine | 1991 |
Pharmacological studies of human erectile tissue: characteristics of spontaneous contractions and alterations in alpha-adrenoceptor responsiveness with age and disease in isolated tissues.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adult; Aged; Aged, 80 and over; Aging; Diabetes Complications; Erectile Dysfunction; Humans; In Vitro Techniques; Indomethacin; Male; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Penile Erection; Penis; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha | 1990 |
Beta adrenergically mediated cardiac chronotropic and vascular smooth muscle responses during propranolol therapy and withdrawal in young and elderly persons.
Topics: Adult; Aged; Aging; Blood Pressure; Female; Heart Rate; Humans; Isoproterenol; Male; Muscle, Smooth, Vascular; Phenylephrine; Propranolol; Stimulation, Chemical; Vasoconstriction | 1992 |
Baroreflex sensitivity and heredity in essential hypertension.
Topics: Administration, Inhalation; Adult; Aging; Forecasting; Humans; Hypertension; Male; Middle Aged; Nitrates; Pentanols; Phenylephrine; Pressoreceptors; Reflex; Regression Analysis | 1992 |
Waning cardiovascular responses to adrenergic drugs in conscious ageing rats.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Epinephrine; Heart Rate; Isoproterenol; Male; Phenylephrine; Rats; Rats, Inbred Strains; Sympathomimetics | 1991 |
Ontogeny of responses of rabbit aorta to atrial natriuretic factor and isoproterenol.
Topics: Aging; Animals; Atrial Natriuretic Factor; Drug Interactions; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Potassium; Rabbits | 1991 |
Plasma immunoreactive endothelin-1 in experimental malignant hypertension.
Topics: Aging; Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Blood Urea Nitrogen; Body Weight; Caffeine; Creatinine; Desoxycorticosterone; Endothelins; Humans; Hypertension, Malignant; Hypertension, Renovascular; Kidney; Male; Phenylephrine; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Artery Obstruction; Renin; Systole | 1991 |
Differential age-dependent attenuation of reflex tachycardia by verapamil in rats.
Topics: Aging; Animals; Atropine; Female; Heart Rate; Nitroprusside; Parasympathetic Nervous System; Phenylephrine; Propranolol; Rats; Rats, Inbred Strains; Reflex; Sympathetic Nervous System; Verapamil | 1991 |
Increase in sympathetic activity with age. I. Role of impairment of arterial baroreflexes.
Topics: Aging; Anesthesia; Animals; Arteries; Atropine; Blood Pressure; Dogs; Heart Rate; Kidney; Male; Nitroglycerin; Phenylephrine; Pressoreceptors; Sympathetic Nervous System | 1991 |
Power spectral analysis of the baroreflex in neonatal swine.
Topics: Aging; Animals; Animals, Newborn; Blood Pressure; Heart Rate; Neck; Nitroprusside; Phenylephrine; Pressoreceptors; Reflex; Splanchnic Nerves; Swine; Sympathetic Nervous System | 1991 |
Effect of aging on alpha-1 adrenergic stimulation of phosphoinositide hydrolysis in various regions of rat brain.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aging; Animals; Binding, Competitive; Brain; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Hydrolysis; Inositol Phosphates; Iodine Radioisotopes; Kinetics; Male; Norepinephrine; Phenethylamines; Phenylephrine; Phosphatidylinositols; Rats; Rats, Inbred F344; Receptors, Adrenergic, alpha; Tetralones | 1990 |
Aging escalates baroreceptor reflex suppression by the posterior hypothalamus in rats.
Topics: Aging; Animals; Blood Pressure; Electric Stimulation; Hypothalamus, Posterior; Male; Phenylephrine; Pressoreceptors; Rats; Rats, Inbred Strains; Reflex; Splanchnic Nerves | 1991 |
Strain differences in baroreflex inhibition by centrally infused enalapril in old rats.
Topics: Aging; Animals; Blood Pressure; Bradycardia; Enalapril; Heart Rate; Infusion Pumps; Injections, Intraventricular; Male; Nitroprusside; Phenylephrine; Pressoreceptors; Rats; Rats, Inbred F344; Rats, Inbred Strains; Reflex; Species Specificity; Tachycardia | 1991 |
Contractile responses of rat aorta to phenylephrine and serotonin, and aging.
Topics: Aging; Animals; Aorta, Thoracic; Caffeine; Calcium; Fura-2; In Vitro Techniques; Isometric Contraction; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Potassium; Rats; Rats, Inbred Strains; Ryanodine; Serotonin | 1991 |
Autonomic regulation of reflex bradycardia in rats declines with age.
Topics: Aging; Animals; Atropine; Autonomic Nervous System; Female; Heart Rate; Nitroprusside; Parasympathetic Nervous System; Phenylephrine; Propranolol; Rats; Rats, Inbred Strains; Sympathetic Nervous System | 1991 |
Disruption of blood-brain barrier during acute hypertension in adult and aged rats.
Topics: Acute Disease; Aging; Albumins; Animals; Arterioles; Blood Pressure; Blood-Brain Barrier; Fluorescein-5-isothiocyanate; Fluoresceins; Hypertension; Male; Phenylephrine; Pia Mater; Rats; Rats, Inbred Strains; Thiocyanates; Venous Pressure | 1990 |
Mediation of reflex tachycardia becomes exclusively beta-adrenergic in old Fischer 344 rats.
Topics: Aging; Animals; Female; Male; Nitroprusside; Phenylephrine; Pressoreceptors; Rats; Rats, Inbred F344; Receptors, Adrenergic, beta; Sympathetic Nervous System; Tachycardia | 1990 |
Effect of age on contractile response to angiotensin II in rat aorta.
Topics: Acetylcholine; Aging; Angiotensin II; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle Development; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred Strains | 1990 |
In vitro vasoconstriction induced by calcium in renovascular hypertensive or old rats.
Topics: Aging; Animals; Blood Pressure; Calcium; Hypertension, Renovascular; Male; Phenylephrine; Rats; Rats, Inbred Strains; Renin; Vasoconstriction | 1990 |
Enhanced sympathetic mediation of chronotropic baroreflexes in old Sprague-Dawley rats.
Topics: Aging; Animals; Atropine Derivatives; Blood Pressure; Efferent Pathways; Heart Rate; Male; Nitroprusside; Phenylephrine; Pressoreceptors; Propranolol; Rats; Rats, Inbred Strains; Reflex; Sympathetic Nervous System | 1990 |
Effect of age on diastolic left ventricular filling at rest and during inotropic stimulation and acute systemic hypertension: experimental studies in conscious beagles.
Topics: Aging; Animals; Blood Flow Velocity; Blood Pressure; Diastole; Dobutamine; Dogs; Echocardiography, Doppler; Heart; Heart Rate; Heart Ventricles; Hypertension; Male; Phenylephrine | 1990 |
Activation of endothelial L-arginine pathway in resistance arteries. Effect of age and hypertension.
Topics: Acetylcholine; Aging; Animals; Arginine; Endothelium, Vascular; Hypertension; Male; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance; Vasoconstriction | 1990 |
Sympathomimetic protein secretion by young and aged lacrimal gland.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Cyclic AMP; Isoenzymes; Isoproterenol; Lacrimal Apparatus; Male; Peroxidase; Peroxidases; Phenylephrine; Proteins; Rats; Rats, Inbred F344; Sympathomimetics; Tears | 1986 |
Electrophysiological and biochemical characterization of the development of alpha 1-adrenergic and 5-HT1 receptors associated with dorsal raphe neurons.
Topics: Action Potentials; Aging; Animals; In Vitro Techniques; Lysergic Acid Diethylamide; Male; Phenylephrine; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Serotonin; Serotonin | 1989 |
Pressor responsiveness, age and hypertension.
Topics: Adult; Aged; Aging; Blood Pressure; Humans; Hypertension; Middle Aged; Phenylephrine; Receptors, Adrenergic, alpha | 1989 |
Effects of age on urinary bladder function in the male rat.
Topics: Aging; Animals; Bethanechol; Bethanechol Compounds; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; Phenylephrine; Pressure; Rats; Rats, Inbred F344; Urinary Bladder; Urination | 1989 |
Myocardial response to alpha-agonist (phenylephrine) in relation to age.
Topics: Adult; Aging; Animals; Depression, Chemical; Heart; Heart Atria; Heart Ventricles; Humans; In Vitro Techniques; Infant; Isoproterenol; Male; Middle Aged; Phenylephrine; Rats; Stimulation, Chemical | 1989 |
Arterial baroreflex abnormalities in heart failure. Reversal after orthotopic cardiac transplantation.
Topics: Adult; Aged; Aging; Arteries; Heart; Heart Failure; Heart Transplantation; Humans; Middle Aged; Phenylephrine; Postoperative Period; Pressoreceptors; Reflex | 1989 |
Age-related central and baroreceptor impairment in female Sprague-Dawley rats.
Topics: Afferent Pathways; Aging; Animals; Aorta; Brain; Electric Stimulation; Female; Nervous System; Nitroprusside; Phenylephrine; Pressoreceptors; Rats; Rats, Inbred Strains; Reflex | 1989 |
Age-related changes in blood pressure, heart rate and baroreflex sensitivity in SHR.
Topics: Aging; Animals; Blood Pressure; Heart Rate; Infusions, Intravenous; Male; Phenylephrine; Pressoreceptors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reflex | 1989 |
Ageing and alpha 1 adrenoceptors in the iris.
Topics: Adult; Aged; Aged, 80 and over; Aging; Dose-Response Relationship, Drug; Humans; Iris; Moxisylyte; Phenylephrine; Pupil; Receptors, Adrenergic, alpha | 1987 |
Iontophoretic study of adrenergic and cholinergic skin vessel reactivity in normal ageing and Alzheimer's disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Autonomic Agents; Humans; Iontophoresis; Isoproterenol; Methacholine Compounds; Middle Aged; Phenylephrine; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Cholinergic; Skin | 1987 |
In vivo demonstration of maturational changes of the chronotropic response to alpha-adrenergic stimulation.
Topics: Aging; Animals; Animals, Newborn; Blood Pressure; Dogs; Heart Rate; Parasympathetic Nervous System; Phentolamine; Phenylephrine; Propranolol; Receptors, Adrenergic, alpha; Stimulation, Chemical; Vagotomy | 1988 |
[Influence of hypertension and age on the sympathetic and parasympathetic components of cardiac baroreflex in the conscious rat].
Topics: Aging; Animals; Atropine; Heart; Hypertension; Male; Parasympathetic Nervous System; Phenylephrine; Pressoreceptors; Propranolol; Rats; Receptors, Adrenergic, beta; Sympathetic Nervous System; Vagus Nerve | 1988 |
Ontogeny of alpha- and beta-adrenergic anorexia in rats.
Topics: Aging; Animals; Anorexia; Appetite; Appetite Depressants; Feeding and Eating Disorders; Female; Isoproterenol; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1988 |
Properties of cardiac alpha- and beta-adrenoceptors in spontaneously hypertensive rats.
Topics: Aging; Animals; Cardiomegaly; Electric Stimulation; Hypertension; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Myocardium; Papillary Muscles; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1988 |
Kinetics of [3H]-prazosin binding to the rat cortex during aging.
Topics: Aging; Animals; Cerebral Cortex; Male; Phentolamine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1988 |
Adrenaline and the development of spontaneous hypertension in rats.
Topics: Adrenal Medulla; Adrenergic beta-Agonists; Aging; Animals; Catecholamines; Chromatography, High Pressure Liquid; Corticosterone; Drug Implants; Electric Stimulation; Epinephrine; Hypertension; Male; Norepinephrine; Phenylephrine; Propanolamines; Rats; Rats, Inbred SHR; Time Factors; Xamoterol | 1985 |
Age-related changes in adrenergic vasoconstrictor responses of the rat hindlimb.
Topics: Adrenergic alpha-Agonists; Adrenergic Fibers; Aging; Animals; Cocaine; Electric Stimulation; Extremities; Male; Methoxamine; Norepinephrine; Phenylephrine; Rats; Rats, Inbred F344; Vasoconstriction | 1987 |
Influences of age on the positive inotropic effect mediated by alpha- and beta-adrenoceptors in rat ventricular strips.
Topics: Aging; Animals; Atenolol; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Stimulation, Chemical | 1985 |
Developmental alteration in adrenergic regulation of hepatic glycogen phosphorylase.
Topics: Aging; Animals; Cyclic AMP; Epinephrine; In Vitro Techniques; Isoproterenol; Liver; Liver Glycogen; Male; Parasympathetic Nervous System; Phenylephrine; Phosphorylases; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1986 |
Age-related alterations in alpha 1- and beta-adrenoceptors mediated responsiveness of rat aorta.
Topics: Aging; Animals; Aorta, Thoracic; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Potassium Chloride; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1987 |
Relationships among airway reactivity, pupillary alpha-adrenergic and cholinergic responsiveness, and age.
Topics: Adolescent; Adult; Aged; Aging; Airway Resistance; Carbachol; Female; Humans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Phenylephrine; Pupil | 1988 |
Pulse-wave model of brachial arterial pressure modulation in aging and hypertension.
Topics: Adult; Aging; Atropine; Blood Pressure; Brachial Artery; Heart Rate; Humans; Hypertension; Mathematics; Models, Cardiovascular; Nitroglycerin; Norepinephrine; Phenylephrine; Vascular Resistance; Vasoconstriction; Vasodilation | 1986 |
Absence of age-related changes in venous responsiveness to nitroglycerin in vivo in humans.
Topics: Adult; Aged; Aging; Dose-Response Relationship, Drug; Humans; Male; Methods; Middle Aged; Nitroglycerin; Phenylephrine; Vasoconstriction; Vasodilation; Veins | 1987 |
[Age-related characteristics of a change in cardiac systolic and diastolic functions under the influence of the adrenergic stimulants isadrin and mezaton (based on data from a computer analysis of the echocardiogram)].
Topics: Adult; Aged; Aged, 80 and over; Aging; Computers; Diastole; Echocardiography; Humans; Isoproterenol; Middle Aged; Myocardial Contraction; Phenylephrine; Systole; Time Factors | 1988 |
Aging and aortic impedance in beagle dogs.
Topics: Aging; Animals; Aorta; Dogs; Female; Hemodynamics; Isoproterenol; Nitroprusside; Phenylephrine; Vascular Resistance | 1988 |
Age-related decline in ligand-induced actin polymerization in human leukocytes and platelets.
Topics: Actins; Adult; Aged; Aging; Blood Platelets; Female; Humans; In Vitro Techniques; Ligands; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phenylephrine; Tetradecanoylphorbol Acetate; Triiodothyronine | 1986 |
Age differences in the baroreceptor response of rats.
Topics: Adrenergic beta-Antagonists; Aging; Animals; Atropine; Blood Pressure; Cardiac Output; Heart Rate; Indicator Dilution Techniques; Male; Parasympathetic Nervous System; Parasympatholytics; Phenylephrine; Pressoreceptors; Propranolol; Rats | 1974 |
Refraction using mydriatic, cycloplegic, and manifest techniques.
Topics: Acrylamides; Adolescent; Adult; Aging; Child; Cyclopentanes; Dimethylamines; Humans; Hyperopia; Methods; Mydriatics; Myopia; Phenylacetates; Phenylephrine; Pyridines; Refraction, Ocular; Refractive Errors; Visual Acuity | 1973 |
The supersensitivity of isolated rabbit atria and aortic strips produced by 6-hydroxydopamine.
Topics: Aging; Animals; Aorta; Barium; Dimethylphenylpiperazinium Iodide; Dopamine; Drug Interactions; Drug Synergism; Epinephrine; Heart Atria; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Nicotine; Norepinephrine; Phenylephrine; Potassium Chloride; Rabbits; Sympathectomy; Sympathetic Nervous System; Tyramine | 1972 |
Effect of age and high blood pressure on baroreflex sensitivity in man.
Topics: Adult; Aged; Aging; Autonomic Nervous System; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Phenylephrine; Pressoreceptors; Pulse; Reflex; Stimulation, Chemical | 1971 |
Decrease in baroreflex sensitivity with increasing arterial pressure and with increasing age.
Topics: Adult; Aged; Aging; Arteries; Blood Pressure; Humans; Hypertension; Middle Aged; Phenylephrine; Pressoreceptors | 1969 |
Adrenergic innervation and cocaine-induced potentiation of adrenergic responses of aortic strips from young and old rabbits.
Topics: Aging; Animals; Aorta, Thoracic; Calcium; Cobalt; Cocaine; Cold Temperature; Drug Synergism; Histocytochemistry; Male; Manganese; Microscopy, Fluorescence; Muscle Contraction; Muscle, Smooth; Nicotine; Norepinephrine; Phenylephrine; Pyrogallol; Rabbits; Receptors, Adrenergic; Reserpine; Tyramine | 1971 |
Diminished baroreflex sensitivity in high blood pressure and ageing man.
Topics: Adult; Aged; Aging; Blood Pressure; Humans; Hypertension; Middle Aged; Phenylephrine; Pressoreceptors; Reflex | 1969 |