Page last updated: 2024-08-16

phenylephrine and Acidosis

phenylephrine has been researched along with Acidosis in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19905 (13.89)18.7374
1990's10 (27.78)18.2507
2000's10 (27.78)29.6817
2010's10 (27.78)24.3611
2020's1 (2.78)2.80

Authors

AuthorsStudies
Lee, A; Ngan Kee, W1
Avidan, A; Knigin, D; Weiniger, CF1
Adams, SC; Arcache, MJ; Dyer, RA; Emmanuel, A; Higgins, N; James, MF; Joolay, Y; Lombard, CJ; Reed, AR; Schulein, S; van Dyk, D; Vorster, A; Wong, CA1
Chilkoti, GT; Duggal, S; Mohta, M1
Hirose, M; Kaneko, T; Kariya, N1
Heesen, M; Hilber, N; Klimek, M; Ngan Kee, WD; Rijs, K; Rossaint, R; van der Marel, C1
Devillier, P; Faisy, C; Grassin-Delyle, S; Lansac, E; Ménasché, P; Naline, E; Vidal, C1
Gander, S; Jain, K; Kumar, P; Makkar, JK; Subramani Vp, S1
Achike, FI; Mustafa, MR; Subramaniam, G1
Coccaro, E; Cojocaru, C; Fliegel, L; Karki, P1
Blouin, JL; Landau, R; Liu, SK; Ngan Kee, WD; Smiley, RM1
Heesen, M; Hofmann, T; Klöhr, S; Rossaint, R; Roth, R; Veeser, M1
Andtbacka, RH; Gifford, JR; Ives, SJ; Morgan, RG; Noyes, RD; Park, SY; Richardson, RS; Symons, JD1
Carpenter, M; Cooper, DW; Desira, WR; Kokri, MS; Mowbray, P; Ryall, DM1
Ohizumi, Y; Rohra, DK; Saito, SY1
BECK, GJ1
Arberry, LA; Choisy, SC; Hancox, JC; James, AF; Reynolds, AM; Shattock, MJ1
Buckwalter, JB; Clifford, PS; Hamann, JJ; Kluess, HA1
Cooper, DW1
Afshari, A; Hangaard, N; Møller, AM1
Cooper, DW; Gibb, SC; Kokri, MS; Koneti, KK; Malik, AT; Meek, T; Owen, S1
Bruandet, N; Quintin, L1
Lee, JA; Orchard, CH; Shah, N; Than, N; White, J1
Clément-Chomienne, O; Pucéat, M; Terzic, A; Vassort, G2
Banerjee, A; Cain, BS; Cleveland, JC; Harken, AH; Meldrum, DR; Rehring, TF; Shapiro, JI1
Beddy, D; Honner, V; McLoughlin, P; O'Regan, RG; Sinnott, B; Sweeney, M1
McLoughlin, P; O'Regan, RG; Sweeney, M1
Carpenter, MR; Cooper, DW1
Brashers, VL; Carey, RM; Dacus, WS; Peach, MJ; Rose, CE; Vance, JE1
Chen, LQ; Shepherd, AP1
Adham, BI; Donley, DK; Goddard-Finegold, J; Michael, LH1
Boachie-Ansah, G; Kane, KA; Parratt, JR1
Kamata, K; Nakanishi, T; Nakazawa, M; Okuda, H; Seguchi, M; Takao, A1
Chancey, B; Farrell, AP; MacLeod, KR1
Bose, D; Greengrass, R; Gregory, G; Ong, BY; Palahniuk, RJ1

Reviews

3 review(s) available for phenylephrine and Acidosis

ArticleYear
Effects of Vasoactive Medications and Maternal Positioning During Cesarean Delivery on Maternal Hemodynamics and Neonatal Acid-Base Status.
    Clinics in perinatology, 2019, Volume: 46, Issue:4

    Topics: Acidosis; Acidosis, Respiratory; Anesthesia, Spinal; Blood Gas Analysis; Cesarean Section; Ephedrine; Female; Fetal Blood; Fetal Hypoxia; Fluid Therapy; Hemodynamics; Humans; Hydrogen-Ion Concentration; Hypotension; Infant, Newborn; Norepinephrine; Patient Positioning; Peripartum Period; Phenylephrine; Placental Circulation; Pregnancy; Pregnancy Complications; Serotonin 5-HT3 Receptor Antagonists; Vasoconstrictor Agents; Vena Cava, Inferior

2019
Ephedrine versus phenylephrine as a vasopressor for spinal anaesthesia-induced hypotension in parturients undergoing high-risk caesarean section: meta-analysis, meta-regression and trial sequential analysis.
    International journal of obstetric anesthesia, 2019, Volume: 37

    Topics: Acidosis; Anesthesia, Obstetrical; Anesthesia, Spinal; Cesarean Section; Ephedrine; Female; Fetal Diseases; Humans; Hypotension; Phenylephrine; Pregnancy; Vasoconstrictor Agents

2019
Vasopressors for the management of hypotension after spinal anesthesia for elective caesarean section. Systematic review and cumulative meta-analysis.
    Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:7

    Topics: Acidosis; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Bradycardia; Cesarean Section; Clinical Trials as Topic; Double-Blind Method; Elective Surgical Procedures; Ephedrine; Female; Fetal Diseases; Hemodynamics; Humans; Hypertension; Hypotension; Infant, Newborn; Multicenter Studies as Topic; Phenylephrine; Pregnancy; Randomized Controlled Trials as Topic; Risk; Treatment Outcome; Vasoconstrictor Agents

2012

Trials

5 trial(s) available for phenylephrine and Acidosis

ArticleYear
A randomised comparison of bolus phenylephrine and ephedrine for the management of spinal hypotension in patients with severe preeclampsia and fetal compromise.
    International journal of obstetric anesthesia, 2018, Volume: 33

    Topics: Acidosis; Adult; Anesthesia, Obstetrical; Blood Pressure; Cesarean Section; Ephedrine; Female; Fetal Blood; Fetal Diseases; Humans; Hydrogen-Ion Concentration; Hypotension; Infant, Newborn; Lactic Acid; Oxygen; Phenylephrine; Pre-Eclampsia; Pregnancy; Vasoconstrictor Agents; Young Adult

2018
Randomised double-blind comparison of bolus phenylephrine or ephedrine for treatment of hypotension in women with pre-eclampsia undergoing caesarean section.
    Anaesthesia, 2018, Volume: 73, Issue:7

    Topics: Acid-Base Imbalance; Acidosis; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Blood Pressure; Cesarean Section; Double-Blind Method; Ephedrine; Female; Heart Rate; Humans; Hypotension; Infant, Newborn; Phenylephrine; Pre-Eclampsia; Pregnancy; Treatment Outcome; Vasoconstrictor Agents

2018
A randomized trial comparing prophylactic phenylephrine and ephedrine infusion during spinal anesthesia for emergency cesarean delivery in cases of acute fetal compromise.
    Journal of clinical anesthesia, 2016, Volume: 34

    Topics: Acidosis; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Apgar Score; Bradycardia; Cesarean Section; Double-Blind Method; Elective Surgical Procedures; Emergencies; Ephedrine; Female; Fetal Distress; Fetus; Hemodynamics; Humans; Hydrogen-Ion Concentration; Hypotension; Infant, Newborn; Phenylephrine; Pregnancy; Prospective Studies; Respiration, Artificial; Umbilical Arteries; Vasoconstrictor Agents; Young Adult

2016
Fetal and maternal effects of phenylephrine and ephedrine during spinal anesthesia for cesarean delivery.
    Anesthesiology, 2002, Volume: 97, Issue:6

    Topics: Acidosis; Adrenergic alpha-Agonists; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Blood Pressure; Cesarean Section; Double-Blind Method; Drug Therapy, Combination; Ephedrine; Female; Fetus; Humans; Infant, Newborn; Phenylephrine; Postoperative Nausea and Vomiting; Pregnancy

2002
Effect of intravenous vasopressor on spread of spinal anaesthesia and fetal acid-base equilibrium.
    British journal of anaesthesia, 2007, Volume: 98, Issue:5

    Topics: Acid-Base Equilibrium; Acidosis; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Cesarean Section; Double-Blind Method; Drug Interactions; Ephedrine; Female; Fetus; Humans; Maternal-Fetal Exchange; Phenylephrine; Pregnancy; Vasoconstrictor Agents

2007

Other Studies

28 other study(ies) available for phenylephrine and Acidosis

ArticleYear
The effect of spinal hypotension and anesthesia-to-delivery time interval on neonatal outcomes in planned cesarean delivery.
    American journal of obstetrics and gynecology, 2020, Volume: 223, Issue:5

    Topics: Acidosis; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Apgar Score; Breech Presentation; Cesarean Section; Cesarean Section, Repeat; Ephedrine; Female; Fetal Macrosomia; Humans; Hypotension; Infant, Newborn; Infant, Newborn, Diseases; Intensive Care, Neonatal; Multivariate Analysis; Phenylephrine; Pregnancy; Respiratory Distress Syndrome, Newborn; Retrospective Studies; Risk Factors; Time Factors; Transient Tachypnea of the Newborn; Vasoconstrictor Agents

2020
Association between intraoperative phenylephrine administration and umbilical artery pH in women with hypertensive disorders of pregnancy: a retrospective cohort study.
    Journal of anesthesia, 2018, Volume: 32, Issue:6

    Topics: Acidosis; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Cesarean Section; Cohort Studies; Female; Humans; Hydrogen-Ion Concentration; Hypertension, Pregnancy-Induced; Hypotension; Phenylephrine; Pregnancy; Retrospective Studies; Umbilical Arteries; Vasoconstrictor Agents

2018
Effect of severe acidosis on vasoactive effects of epinephrine and norepinephrine in human distal mammary artery.
    The Journal of thoracic and cardiovascular surgery, 2014, Volume: 147, Issue:5

    Topics: Acidosis; Adrenergic alpha-Agonists; Aged; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Female; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Mammary Arteries; Methoxamine; Middle Aged; Norepinephrine; Phenylephrine; Receptors, Adrenergic; Vasoconstriction; Vasoconstrictor Agents

2014
Effect of acidosis on the mechanism(s) of insulin-induced vasorelaxation in normal Wistar-Kyoto (WKY) rat aorta.
    Regulatory peptides, 2009, Jun-05, Volume: 155, Issue:1-3

    Topics: 4-Aminopyridine; Acidosis; Animals; Aorta; Barium Compounds; Chlorides; Endothelium, Vascular; Glyburide; Hydrogen-Ion Concentration; Hypoglycemic Agents; Indomethacin; Insulin; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Ouabain; Phenylephrine; Potassium Channel Blockers; Rats; Rats, Inbred WKY; Tetraethylammonium; Vasoconstriction; Vasodilation

2009
Phenylephrine and sustained acidosis activate the neonatal rat cardiomyocyte Na+/H+ exchanger through phosphorylation of amino acids Ser770 and Ser771.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:2

    Topics: Acidosis; Adenoviridae; Animals; Animals, Newborn; Cardiotonic Agents; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; MAP Kinase Signaling System; Mutagenesis; Myocytes, Cardiac; Phenylephrine; Phosphorylation; Rats; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers

2009
The effect of maternal and fetal β2-adrenoceptor and nitric oxide synthase genotype on vasopressor requirement and fetal acid-base status during spinal anesthesia for cesarean delivery.
    Anesthesia and analgesia, 2011, Volume: 112, Issue:6

    Topics: Acidosis; Anesthesia, Obstetrical; Anesthesia, Spinal; Cesarean Section; China; Codon; Ephedrine; Female; Genotype; Haplotypes; Humans; Hydrogen-Ion Concentration; Nitric Oxide Synthase; Phenylephrine; Receptors, Adrenergic, beta-2; Regression Analysis; Vasoconstrictor Agents

2011
α1-Adrenergic responsiveness in human skeletal muscle feed arteries: the impact of reducing extracellular pH.
    Experimental physiology, 2013, Volume: 98, Issue:1

    Topics: Acidosis; Adult; Aged; Aged, 80 and over; Arteries; Female; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Muscle, Skeletal; Muscle, Smooth, Vascular; Phenylephrine; Receptors, Adrenergic, alpha-1; Vasoconstriction; Vasodilation

2013
Strain-specific effects of acidic pH on contractile state of aortas from Wistar and Wistar Kyoto rats.
    European journal of pharmacology, 2003, Aug-22, Volume: 476, Issue:1-2

    Topics: Acidosis; Animals; Aorta; Calcium; Delayed Rectifier Potassium Channels; Extracellular Fluid; Hydrogen-Ion Concentration; In Vitro Techniques; Isometric Contraction; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Potassium Channels; Potassium Channels, Voltage-Gated; Rats; Rats, Inbred WKY; Rats, Wistar; Species Specificity; Vasoconstrictor Agents

2003
ADVANCES IN PHYSIOLOGIC TECHNICS FOR REHABILITATION OF ASTHMATIC PATIENT.
    New York state journal of medicine, 1964, Apr-15, Volume: 64

    Topics: Acidosis; Adrenal Cortex Hormones; Aerosols; Anti-Bacterial Agents; Asthma; Breathing Exercises; Diet, Sodium-Restricted; Digitalis; Digitalis Glycosides; Diuretics; Epinephrine; Expectorants; Humans; Isoproterenol; Oxygen Inhalation Therapy; Phenylephrine; Positive-Pressure Respiration; Prednisone; Respiratory Therapy; Theophylline; Tracheotomy

1964
Evidence for a novel K(+) channel modulated by alpha(1A)-adrenoceptors in cardiac myocytes.
    Molecular pharmacology, 2004, Volume: 66, Issue:3

    Topics: Acidosis; Animals; Electrophysiology; GTP-Binding Proteins; Heart; Male; Myocytes, Cardiac; Nerve Tissue Proteins; Pertussis Toxin; Phenylephrine; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Sodium-Activated; Potassium Channels, Tandem Pore Domain; Quinidine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Signal Transduction; Tetraethylammonium; Time Factors

2004
Acidosis attenuates P2X purinergic vasoconstriction in skeletal muscle arteries.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:1

    Topics: Acidosis; Adenosine Triphosphate; Animals; Arteries; Hydrogen-Ion Concentration; Male; Muscle, Skeletal; Phenylephrine; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2X; Vasoconstriction

2005
Ephedrine, phenylephrine and fetal acidosis.
    Anaesthesia, 2005, Volume: 60, Issue:12

    Topics: Acidosis; Anesthesia, Obstetrical; Ephedrine; Female; Fetal Diseases; Humans; Maternal-Fetal Exchange; Phenylephrine; Pregnancy

2005
[Comparison of prophylactic infusion of ephedrine and phenylephrine during Cesarean section under spinal anaesthesia].
    Ugeskrift for laeger, 2006, Apr-03, Volume: 168, Issue:14

    Topics: Acidosis; Adrenergic alpha-Agonists; Anesthesia, Obstetrical; Anesthesia, Spinal; Cesarean Section; Ephedrine; Female; Humans; Hypotension; Infant, Newborn; Infusions, Intravenous; Phenylephrine; Pregnancy; Vasoconstrictor Agents

2006
Systemic acidosis after controlled hypotension activates catechol activity in the vasomotor center.
    Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 76, Issue:6

    Topics: Acidosis; Animals; Blood Gas Analysis; Blood Pressure; Catechols; Hypercapnia; Hypotension, Controlled; Male; Medulla Oblongata; Neurons; Nitroprusside; Phenylephrine; Rats; Rats, Sprague-Dawley

1994
Effects of acidosis and hypoxia on the response of isolated ferret cardiac muscle to inotropic agents.
    Cardiovascular research, 1994, Volume: 28, Issue:8

    Topics: Acidosis; Animals; Calcium; Cardiotonic Agents; Dose-Response Relationship, Drug; Ferrets; Hypoxia; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Norepinephrine; Papillary Muscles; Phenylephrine; Quinolines; Stimulation, Chemical; Thiadiazines

1994
Alpha 1-adrenoceptor and purinoceptor agonists modulate Na-H antiport in single cardiac cells.
    The American journal of physiology, 1993, Volume: 264, Issue:2 Pt 2

    Topics: Acidosis; Adenosine Triphosphate; Adrenergic alpha-Agonists; Ammonium Chloride; Animals; Calcium; Carrier Proteins; Cell Separation; Electrophysiology; Hydrogen-Ion Concentration; Myocardium; Phenylephrine; Protein Kinase C; Rats; Receptors, Purinergic; Sodium-Hydrogen Exchangers

1993
Mechanisms of pH preservation during global ischemia in preconditioned rat heart: roles for PKC and NHE.
    The American journal of physiology, 1998, Volume: 275, Issue:3

    Topics: Acidosis; Adenosine Triphosphate; Adrenergic alpha-Agonists; Amiloride; Animals; Guanidines; Hydrogen-Ion Concentration; Ischemic Preconditioning, Myocardial; Kinetics; Male; Myocardial Ischemia; Phenylephrine; Phosphates; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium-Hydrogen Exchangers; Sulfones

1998
Effects of changes in pH and CO2 on pulmonary arterial wall tension are not endothelium dependent.
    Journal of applied physiology (Bethesda, Md. : 1985), 1998, Volume: 85, Issue:6

    Topics: Acetylcholine; Acidosis; Animals; Carbon Dioxide; Endothelium, Vascular; Enzyme Inhibitors; Hydrogen-Ion Concentration; Hypercapnia; In Vitro Techniques; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenylephrine; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vasoconstriction

1998
Effects of changes in pH and PCO2 on wall tension in isolated rat intrapulmonary arteries.
    Experimental physiology, 1999, Volume: 84, Issue:3

    Topics: Acidosis; Animals; Carbon Dioxide; Carotid Arteries; Dinoprost; Hydrogen-Ion Concentration; Hypercapnia; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Phenylephrine; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vasoconstriction

1999
Fetal acidosis, spinal anaesthesia and phenylephrine.
    Anaesthesia, 2001, Volume: 56, Issue:9

    Topics: Acidosis; Anesthesia, Obstetrical; Anesthesia, Spinal; Cardiotonic Agents; Cesarean Section; Female; Fetal Diseases; Humans; Phenylephrine; Pregnancy; Retrospective Studies

2001
Phenylephrine and ATP enhance an amiloride insensitive bicarbonate-dependent alkalinizing mechanism in rat single cardiomyocytes.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 346, Issue:5

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acidosis; Adenosine Triphosphate; Amiloride; Animals; Bicarbonates; Culture Media; Heart; Hydrogen-Ion Concentration; In Vitro Techniques; Myocardium; Phenylephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha

1992
Role of intrarenal angiotensin II and alpha-adrenoceptors in renal vasoconstriction with acute hypoxemia and hypercapnic acidosis in conscious dogs.
    Circulation research, 1991, Volume: 69, Issue:1

    Topics: Acidosis; Acute Disease; Adrenergic alpha-Antagonists; Angiotensin II; Animals; Dogs; Hypercapnia; Hypoxia; Kidney; Pharmaceutical Vehicles; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Renal Circulation; Saralasin; Vasoconstriction

1991
Role of H+ and alpha 2-receptors in escape from sympathetic vasoconstriction.
    The American journal of physiology, 1991, Volume: 261, Issue:3 Pt 2

    Topics: Acidosis; Analysis of Variance; Animals; Blood Pressure; Clonidine; Dogs; Electric Stimulation; Female; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Receptors, Purinergic; Sympathetic Nervous System; Time Factors; Vasoconstriction

1991
Phenobarbital and cerebral blood flow during hypertension in the newborn beagle.
    Pediatrics, 1990, Volume: 86, Issue:4

    Topics: Acidosis; Animals; Animals, Newborn; Cerebral Hemorrhage; Cerebrovascular Circulation; Dogs; Hemodynamics; Hypertension; Microspheres; Phenobarbital; Phenylephrine

1990
Cardiac electrophysiological effects of isoprenaline, phenylephrine, and noradrenaline on normal and mildly "ischaemic" sheep Purkinje fibers.
    Journal of cardiovascular pharmacology, 1989, Volume: 13, Issue:2

    Topics: Acidosis; Action Potentials; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Coronary Disease; Electrophysiology; Heart Conduction System; Hyperkalemia; Hypoxia; In Vitro Techniques; Isoproterenol; Membrane Potentials; Norepinephrine; Phenylephrine; Purkinje Fibers; Sheep

1989
Influence of acidosis on inotropic effect of catecholamines in newborn rabbit hearts.
    The American journal of physiology, 1987, Volume: 253, Issue:6 Pt 2

    Topics: Acidosis; Adenylyl Cyclases; Animals; Animals, Newborn; Bucladesine; Calcium; Catecholamines; Cyclic AMP; Hydrogen-Ion Concentration; Isoproterenol; Myocardial Contraction; Myocardium; Perfusion; Phenylephrine; Pindolol; Rabbits; Receptors, Adrenergic, beta

1987
Intrinsic mechanical properties of the perfused rainbow trout heart and the effects of catecholamines and extracellular calcium under control and acidotic conditions.
    The Journal of experimental biology, 1986, Volume: 125

    Topics: Acidosis; Animals; Calcium; Catecholamines; Epinephrine; Heart; In Vitro Techniques; Isoproterenol; Norepinephrine; Perfusion; Phenylephrine; Trout

1986
Acidemia impairs autoregulation of cerebral blood flow in newborn lambs.
    Canadian Anaesthetists' Society journal, 1986, Volume: 33, Issue:1

    Topics: Acidosis; Animals; Animals, Newborn; Blood Pressure; Cerebrovascular Circulation; Heart Rate; Homeostasis; Lactates; Phenylephrine; Sheep

1986