phenylephrine has been researched along with Ache in 43 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (11.63) | 18.7374 |
| 1990's | 14 (32.56) | 18.2507 |
| 2000's | 11 (25.58) | 29.6817 |
| 2010's | 10 (23.26) | 24.3611 |
| 2020's | 3 (6.98) | 2.80 |
| Authors | Studies |
|---|---|
| Donnenfeld, ED; Mychajlyszyn, A; Mychajlyszyn, D; Stein, R | 1 |
| Bedi, R; Visco, DM | 1 |
| Birklein, F; Drummond, PD; Lemper, C; Lismont, NCAM; Morellini, N; Schlereth, T | 1 |
| Ianchulev, T; Lin, S; Pasquale, LR; Tsai, JC; Weinreb, R | 1 |
| Birklein, F; Drummond, PD; Finch, PM; Knudsen, LF; Morellini, N | 1 |
| Slater, R | 1 |
| Cheek, JA; Craig, SS; Egerton-Warburton, D; Paul, E; Seith, RW; West, A; Wilson, K | 1 |
| Cheek, JA; Craig, SS; Egerton-Warburton, D; Seith, RW; West, A; Wilson, K | 1 |
| Buinewicz, JD; Freeman, K; Gutierrez, K; Manning, CT; O'Keefe, MF; Sewatsky, TP; Zgonis, E | 1 |
| Hajioff, D; Hussain, A; Javed, F; Parmar, A; Pinder, D | 1 |
| Budgell, B; Kurosawa, M; Maruyama, H; Toda, H | 1 |
| Bray, RC; Hart, DA; Leonard, C; Mammoto, T; Miller, D; Salo, P | 1 |
| Kohase, H; Makino, K; Sanada, T; Umino, M | 2 |
| Chen, JW; English, J; Jeske, AH; Reznik, DS | 1 |
| Gmiro, VE; Serdiuk, SE | 1 |
| Cara, DM; Neale, LJ; Norris, AM | 1 |
| Bennett, GJ; Mailis-Gagnon, A | 1 |
| Rocco, AG | 1 |
| Frosh, A; Georgalas, C; Sandhu, G; Xenellis, J | 1 |
| Cheevers, CV; Donello, JE; Gil, DW | 1 |
| Chan, JY; Chan, SH; Kuo, TB; Tsai, HF | 2 |
| Behbehani, MM; Cahall, M; Crews, JC | 1 |
| Brand, PH; Britton, SL; Metting, PJ; Steele, JE | 1 |
| Calixto, JB; Filho, VC; Santos, AR; Yunes, RA | 1 |
| Helton, ES; Thurston, CL | 1 |
| Choi, B; Rowbotham, MC | 1 |
| Cohen, DM; Harbeck-Weber, C; Powers, JD; Shields, BJ; Smith, GA; Strausbaugh, SD | 1 |
| Barrett, T; Cohen, DM; Harbeck-Weber, C; Powers, JD; Shields, BJ; Smith, GA; Strausbaugh, SD | 1 |
| Konia, N; Singer, AJ | 1 |
| Dougherty, PM; Oppenheimer, SM; Zhang, ZH | 1 |
| Zaczek, A; Zetterström, C | 1 |
| Cameron, NE; Cotter, MA; Jack, AM | 1 |
| Kawamoto, M; Kinoshita, H; Kusunoki, S; Maehara, Y; Nakagawa, I; Nakao, M; Okida, M; Sasaki, H; Yuge, O | 1 |
| Frankhof, W; Thiemer, K | 1 |
| Campbell, JN; Davis, KD; Meyer, RA; Raja, SN; Treede, RD | 1 |
| Chorev, M; Devor, M; Gilon, C; Papir-Kricheli, D; Selinger, Z | 1 |
| Aran, S; Proudfit, HK | 1 |
| Barr, GA; Hughes, HE | 1 |
| Antonaci, F; Fragoso, YD; Sjaastad, O | 1 |
| Aranda, JV; Beharry, K; Chemtob, S; Laudignon, N; Rex, J | 1 |
| Vorherr, H | 1 |
15 trial(s) available for phenylephrine and Ache
| Article | Year |
|---|---|
Pain control and reduction of opioid use associated with intracameral phenylephrine1.0%-ketorolac 0.3% administered during cataract surgery.
Topics: Analgesics, Opioid; Cataract; Double-Blind Method; Epinephrine; Fentanyl; Humans; Ketorolac; Pain; Pain, Postoperative; Phenylephrine; Prospective Studies | 2022 |
High-precision piezo-ejection ocular microdosing: Phase II study on local and systemic effects of topical phenylephrine.
Topics: Administration, Topical; Adult; Blood Pressure; Cross-Over Studies; Drug Carriers; Drug Compounding; Female; Heart Rate; Humans; Male; Ophthalmic Solutions; Pain; Phenylephrine; Respiratory Tract Infections; Young Adult | 2018 |
Lidocaine and phenylephrine versus saline placebo nasal spray for the pain and distress of nasogastric tube insertion in young children and infants: a randomised, double-blind, controlled trial.
Topics: Anesthetics, Local; Child; Child, Preschool; Double-Blind Method; Female; Humans; Infant; Intubation, Gastrointestinal; Lidocaine; Male; Nasal Sprays; Nebulizers and Vaporizers; Pain; Perioperative Care; Phenylephrine | 2019 |
Lignocaine/phenylephrine nasal spray vs. placebo for the pain and distress of nasogastric tube insertion in children: a study protocol for a randomized controlled trial.
Topics: Child, Preschool; Clinical Protocols; Double-Blind Method; Drug Combinations; Humans; Infant; Intubation, Gastrointestinal; Lidocaine; Nasal Sprays; Pain; Phenylephrine; Prospective Studies | 2015 |
Does Routine Midazolam Administration Prior to Nasogastric Tube Insertion in the Emergency Department Decrease Patients' Pain? (A Pilot Study).
Topics: Adult; Anesthesia; Double-Blind Method; Drug Combinations; Emergency Service, Hospital; Female; Humans; Hypnotics and Sedatives; Intubation, Gastrointestinal; Lidocaine; Male; Midazolam; Middle Aged; Pain; Pain Management; Pain Measurement; Phenylephrine; Pilot Projects; Premedication | 2016 |
A randomised controlled trial assessing the efficacy of co-phenylcaine nasal spray in flexible transnasal pharyngolaryngoscopy.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Double-Blind Method; Drug Combinations; Female; Humans; Laryngoscopy; Lidocaine; Male; Middle Aged; Nasal Cavity; Nasal Decongestants; Nasal Sprays; Natural Orifice Endoscopic Surgery; Pain; Phenylephrine; Young Adult | 2017 |
Comparative efficacy of 2 topical anesthetics for the placement of orthodontic temporary anchorage devices.
Topics: Adolescent; Adult; Aged; Anesthesia, Dental; Anesthetics, Combined; Anesthetics, Local; Benzocaine; Child; Cross-Over Studies; Double-Blind Method; Female; Heart Rate; Humans; Lidocaine; Male; Middle Aged; Orthodontic Anchorage Procedures; Orthodontic Appliances; Oximetry; Pain; Pain Measurement; Phenylephrine; Tetracaine; Time Factors; Vasoconstrictor Agents; Young Adult | 2009 |
Pain during awake nasal intubation after topical cocaine or phenylephrine/lidocaine spray.
Topics: Administration, Intranasal; Adult; Aerosols; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Cocaine; Cross-Over Studies; Female; Humans; Intubation, Intratracheal; Lidocaine; Male; Pain; Pain Measurement; Phenylephrine | 2003 |
Cophenylcaine spray vs. placebo in flexible nasendoscopy: a prospective double-blind randomised controlled trial.
Topics: Administration, Intranasal; Analysis of Variance; Anesthetics, Combined; Double-Blind Method; Endoscopy; Female; Fiber Optic Technology; Humans; Lidocaine; Male; Middle Aged; Nasal Cavity; Nose Diseases; Pain; Phenylephrine; Prospective Studies; Taste Disorders | 2005 |
Effect of adrenergic receptor activation on post-herpetic neuralgia pain and sensory disturbances.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Blood Pressure; Double-Blind Method; Epinephrine; Female; Heart Rate; Herpes Zoster; Humans; Male; Middle Aged; Neuralgia; Neurons, Afferent; Pain; Pain Threshold; Phenylephrine; Skin; Skin Physiological Phenomena; Time Factors | 1997 |
New non-cocaine-containing topical anesthetics compared with tetracaine-adrenaline-cocaine during repair of lacerations.
Topics: Adolescent; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Child; Child, Preschool; Cocaine; Epinephrine; Female; Humans; Infant; Lidocaine; Male; Pain; Phenylephrine; Prilocaine; Prospective Studies; Suture Techniques; Tetracaine; Wounds and Injuries | 1997 |
Prilocaine-phenylephrine and bupivacaine-phenylephrine topical anesthetics compared with tetracaine-adrenaline-cocaine during repair of lacerations.
Topics: Adolescent; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Cocaine; Dermatologic Surgical Procedures; Double-Blind Method; Emergency Service, Hospital; Epinephrine; Female; Hospitals, Pediatric; Humans; Infant; Male; Pain; Pain Measurement; Phenylephrine; Prilocaine; Prospective Studies; Safety; Skin; Suture Techniques; Tetracaine; Vasoconstrictor Agents | 1998 |
Comparison of topical anesthetics and vasoconstrictors vs lubricants prior to nasogastric intubation: a randomized, controlled trial.
Topics: Administration, Topical; Anesthetics, Local; Female; Humans; Intubation, Gastrointestinal; Lubrication; Male; Middle Aged; Pain; Phenylephrine; Prospective Studies; Vasoconstrictor Agents | 1999 |
A prospective multicenter trial to determine the incidence of transient neurologic symptoms after spinal anesthesia with phenylephrine added to 0.5% tetracaine.
Topics: Anesthesia, Spinal; Anesthetics, Local; Double-Blind Method; Elective Surgical Procedures; Female; Gynecologic Surgical Procedures; Humans; Japan; Male; Middle Aged; Nervous System Diseases; Pain; Phenylephrine; Postoperative Complications; Tetracaine; Urologic Surgical Procedures; Vasoconstrictor Agents | 2001 |
[Treatment of distortions and non-traumatic conditions of pain and swelling. Double-blind trial with an analgetic and detumescent drug combination].
Topics: Acetaminophen; Adult; Double-Blind Method; Drug Combinations; Drug Synergism; Edema; Humans; Joint Diseases; Pain; Phenylephrine | 1978 |
28 other study(ies) available for phenylephrine and Ache
| Article | Year |
|---|---|
Effect of intracameral phenylephrine 1.0%-ketorolac 0.3% on postoperative cystoid macular edema, iritis, pain, and photophobia after cataract surgery.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cataract; Cataract Extraction; Cohort Studies; Humans; Iritis; Ketorolac; Macular Edema; Pain; Phacoemulsification; Phenylephrine; Photophobia; Postoperative Complications; Retrospective Studies | 2020 |
Alpha 1 adrenoceptor expression in skin, nerves and blood vessels of patients with painful diabetic neuropathy.
Topics: Diabetes Mellitus; Diabetic Neuropathies; Humans; Pain; Phenylephrine; Receptors, Adrenergic, alpha-1; Skin | 2021 |
Complex regional pain syndrome: intradermal injection of phenylephrine evokes pain and hyperalgesia in a subgroup of patients with upregulated α1-adrenoceptors on dermal nerves.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Adult; Aged; Clonidine; Complex Regional Pain Syndromes; Female; Humans; Hyperalgesia; Injections, Intradermal; Male; Middle Aged; Pain; Phenylephrine; Receptors, Adrenergic, alpha-1; Receptors, Purinergic P2X3; Up-Regulation; Young Adult | 2018 |
The challenge of distinguishing pain from distress in young children.
Topics: Child; Child, Preschool; Double-Blind Method; Humans; Infant; Lidocaine; Nasal Sprays; Pain; Phenylephrine | 2019 |
Responses of dorsal spinal cord blood flow to noxious mechanical stimulation of the skin in anesthetized rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anesthesia, General; Animals; Blood Pressure; Cervical Plexus; Denervation; Injections, Intravenous; Laser-Doppler Flowmetry; Lumbosacral Region; Male; Pain; Phenoxybenzamine; Phenylephrine; Physical Stimulation; Pressoreceptors; Rats; Rats, Wistar; Regional Blood Flow; Skin; Spinal Cord | 2008 |
Neural stimulation does not mediate attenuated vascular response in ACL-deficient knees: potential role of local inflammatory mediators.
Topics: Adrenergic alpha-Agonists; Animals; Anterior Cruciate Ligament Injuries; Denervation; Disease Models, Animal; Dose-Response Relationship, Drug; Inflammation; Inflammation Mediators; Medial Collateral Ligament, Knee; Neuropeptide Y; Osteoarthritis, Knee; Pain; Phenylephrine; Physical Stimulation; Rabbits; Regional Blood Flow; Vasoconstriction | 2010 |
Effects of alpha-adrenergic agonists on pain modulation in diffuse noxious inhibitory control.
Topics: Adrenergic alpha-Agonists; Adrenergic Antagonists; Animals; Dexmedetomidine; Electromyography; Injections, Spinal; Male; Nerve Fibers, Unmyelinated; Nerve Net; Neural Inhibition; Nociceptors; Pain; Phentolamine; Phenylephrine; Rats; Rats, Wistar | 2009 |
Phenylephrine suppresses the pain modulation of diffuse noxious inhibitory control in rats.
Topics: Adrenergic alpha-Agonists; Animals; Central Nervous System; Electric Stimulation; Electromyography; Hot Temperature; Male; Microinjections; Nerve Fibers, Unmyelinated; Nerve Net; Neurons; Nociceptors; Pain; Phenylephrine; Rats; Rats, Sprague-Dawley; Reflex; Sample Size; Sural Nerve | 2010 |
[Peripheral acting mediators pain and analgesia potentiate the central analgesic action of fentanyl and dipyrone].
Topics: Adenosine; Adenosine Triphosphate; Analgesia; Analgesics; Animals; Dipyrone; Dose-Response Relationship, Drug; Drug Synergism; Fentanyl; Glutamic Acid; Male; Pain; Phenylephrine; Rats; Rats, Wistar | 2012 |
Abnormal contralateral pain responses from an intradermal injection of phenylephrine in a subset of patients with complex regional pain syndrome (CRPS).
Topics: Complex Regional Pain Syndromes; Humans; Injections, Intradermal; Pain; Phenylephrine; Sympathectomy | 2004 |
Comment on: Abnormal contralateral pain responses from an intradermal injection of phenylephrine in a subset of patients with complex regional pain syndrome (CRPS).
Topics: Complex Regional Pain Syndromes; Humans; Injections, Intradermal; Pain; Phenylephrine; Sympathectomy | 2005 |
Transient allodynia pain models in mice for early assessment of analgesic activity.
Topics: Adrenergic alpha-Antagonists; Amines; Amitriptyline; Analgesics; Animals; Clonidine; Cyclohexanecarboxylic Acids; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Injections, Intraperitoneal; Injections, Spinal; Male; Memantine; Mice; Mice, Inbred C57BL; Morphine; N-Methylaspartate; Pain; Peripheral Nervous System; Phenylephrine; Piperazines; Prostaglandin Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, N-Methyl-D-Aspartate; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Reproducibility of Results; Spinal Cord; Spinal Nerves; Time Factors | 2008 |
Interaction between neuronal responses to nociception and hypertension in the nucleus reticularis gigantocellularis of the rat.
Topics: Anesthesia; Animals; Basal Ganglia; Blood Pressure; Evoked Potentials; Hypertension; Male; Neurons; Nociceptors; Pain; Pain Threshold; Pentobarbital; Phenylephrine; Rats; Rats, Sprague-Dawley | 1994 |
Modulation by angiotensin III of nociception-related and arterial pressure-related neuronal responsiveness in the nucleus reticularis gigantocellularis of the rat.
Topics: Angiotensin III; Animals; Blood Pressure; Brain Mapping; Electrophysiology; Male; Medulla Oblongata; Neurons; Nociceptors; Pain; Phenylephrine; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
The neurophysiologic mechanisms of tourniquet pain. The activity of neurons in the rostroventral medulla in the rat.
Topics: Animals; Blood Pressure; Hypertension; Male; Medulla Oblongata; Models, Biological; Nerve Compression Syndromes; Neurons; Nociceptors; Pain; Pain Measurement; Phenylephrine; Rats; Rats, Sprague-Dawley; Tourniquets | 1994 |
Dynamic, short-term coupling between changes in arterial pressure and urine flow.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Blood Pressure; Diuresis; Kidney; Male; Pain; Phenylephrine; Rats; Rats, Sprague-Dawley; Renal Artery | 1993 |
Analysis of the mechanisms underlying the antinociceptive effect of the extracts of plants from the genus Phyllanthus.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Arginine; Capsaicin; Clonidine; Male; Mice; Nitroarginine; Pain; Phenylephrine; Plant Extracts; Prazosin; Yohimbine | 1995 |
Effects of intravenous phenylephrine on blood pressure, nociception, and neural activity in the rostral ventral medulla in rats.
Topics: Analysis of Variance; Anesthetics; Animals; Blood Pressure; Dose-Response Relationship, Drug; Electrophysiology; Injections, Intravenous; Male; Medulla Oblongata; Neurons; Nociceptors; Pain; Phenylephrine; Rats; Rats, Sprague-Dawley; Time Factors; Vasoconstrictor Agents | 1996 |
Monkey insular cortex neurons respond to baroreceptive and somatosensory convergent inputs.
Topics: Animals; Blood Pressure; Brain Mapping; Cerebral Cortex; Macaca fascicularis; Male; Neurons; Nitroprusside; Pain; Phenylephrine; Physical Stimulation; Pressoreceptors; Somatosensory Cortex | 1999 |
The effect of phenylephrine on pain and flare intensity in eyes with uveitis.
Topics: Adult; Aged; Aged, 80 and over; Anterior Chamber; Aqueous Humor; Diagnostic Techniques, Ophthalmological; Eye Proteins; Female; Humans; Iridocyclitis; Male; Middle Aged; Mydriatics; Ophthalmic Solutions; Pain; Pain Measurement; Phenylephrine; Prospective Studies; Pupil | 2000 |
Effect of alpha-lipoic acid on vascular responses and nociception in diabetic rats.
Topics: Animals; Antioxidants; Blood Flow Velocity; Diabetes Mellitus, Experimental; Endothelium, Vascular; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Pain; Phenylephrine; Rats; Rats, Sprague-Dawley; Superior Cervical Ganglion; Thioctic Acid; Vasoconstrictor Agents; Vasodilation | 2001 |
Topical application of clonidine relieves hyperalgesia in patients with sympathetically maintained pain.
Topics: Administration, Cutaneous; Adult; Clonidine; Female; Humans; Hyperalgesia; Norepinephrine; Pain; Phenylephrine; Receptors, Adrenergic, alpha; Skin; Sympathetic Nervous System | 1991 |
Neurochemical mediators of the behavioural effects of receptor-selective substance P agonists administered intrathecally in the rat.
Topics: Animals; Injections, Spinal; Male; Methysergide; Morphine; Muscles; Naloxone; Pain; Peptide Fragments; Phentolamine; Phenylephrine; Posture; Rats; Rats, Inbred Strains; Serotonin; Spinal Cord; Stereotyped Behavior; Substance P | 1990 |
Antinociceptive interactions between intrathecally administered alpha noradrenergic agonists and 5'-N-ethylcarboxamide adenosine.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analgesia; Animals; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Hot Temperature; Injections, Spinal; Male; Norepinephrine; Pain; Phenylephrine; Rats; Rats, Inbred Strains; Spinal Cord; Vasodilator Agents | 1990 |
Analgesic effects of intrathecally applied noradrenergic compounds in the developing rat: differences due to thermal vs mechanical nociception.
Topics: Analgesia; Animals; Animals, Newborn; Clonidine; Hot Temperature; Injections, Spinal; Nociceptors; Norepinephrine; Pain; Phenylephrine; Physical Stimulation; Rats; Reference Values; Spinal Cord | 1988 |
Cluster headache: further observations on the dissociation of pain and autonomic findings.
Topics: Autonomic Nervous System; Cluster Headache; Forehead; Horner Syndrome; Humans; Male; Middle Aged; p-Hydroxyamphetamine; Pain; Phenylephrine; Pupil; Sweating; Vascular Headaches | 1988 |
Effect of phenobarbital on cerebral blood flow in the newborn piglet under stress.
Topics: Animals; Animals, Newborn; Blood Pressure; Cardiac Output; Cerebrovascular Circulation; Heart Rate; Pain; Phenobarbital; Phenylephrine; Stress, Physiological; Swine | 1986 |
Catecholamine antagonism to oxytocin-induced milk-ejection.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Animals; Blood Pressure; Catecholamines; Epinephrine; Female; Isoproterenol; Lactation; Mammary Glands, Animal; Norepinephrine; Oxytocin; Pain; Phenoxybenzamine; Phenylephrine; Pregnancy; Propranolol; Rabbits; Rats | 1971 |