Page last updated: 2024-08-25

phenylenediamine mustard and Melanoma

phenylenediamine mustard has been researched along with Melanoma in 3 studies

*Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445) [MeSH]

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hansch, C; Leo, A; Panthananickal, A1
Carl, PL; Chakravarty, PK; Katzenellenbogen, JA; Weber, MJ1
Hellström, I; Hellström, KE; Kerr, DE; Schreiber, GJ; Senter, PD; Svensson, HP; Vrudhula, VM1

Other Studies

3 other study(ies) available for phenylenediamine mustard and Melanoma

ArticleYear
Structure-activity relationship of aniline mustards acting against B-16 melanoma in mice.
    Journal of medicinal chemistry, 1979, Volume: 22, Issue:10

    Topics: Aniline Mustard; Animals; Antineoplastic Agents; Melanoma; Mice; Neoplasms, Experimental; Nitrogen Mustard Compounds; Structure-Activity Relationship

1979
Plasmin-activated prodrugs for cancer chemotherapy. 1. Synthesis and biological activity of peptidylacivicin and peptidylphenylenediamine mustard.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:5

    Topics: Animals; Antineoplastic Agents; Biotransformation; Cell Survival; Cell Transformation, Neoplastic; Female; Fibrinolysin; Isoxazoles; Melanoma; Mice; Nitrogen Mustard Compounds; Oligopeptides; Ovarian Neoplasms; Oxazoles; Plasminogen Activators

1983
Regressions and cures of melanoma xenografts following treatment with monoclonal antibody beta-lactamase conjugates in combination with anticancer prodrugs.
    Cancer research, 1995, Aug-15, Volume: 55, Issue:16

    Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; beta-Lactamases; Cephalosporins; Doxorubicin; Female; Humans; Immunoconjugates; Melanoma; Melanoma-Specific Antigens; Mice; Mice, Nude; Neoplasm Proteins; Neoplasm Transplantation; Nitrogen Mustard Compounds; Prodrugs

1995