phenylbutazone has been researched along with Thrombocytopenia in 27 studies
Phenylbutazone: A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
phenylbutazone : A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.
Thrombocytopenia: A subnormal level of BLOOD PLATELETS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two examples of hematological toxicity following phenylbutazone therapy are described, one of agranulocytosis and one of aplastic anemia." | 3.64 | HEMATOLOGICAL COMPLICATIONS OF PHENYLBUTAZONE THERAPY: REVIEW OF THE LITERATURE AND REPORT OF TWO CASES. ( CHALMERS, TM; MCCARTHY, DD, 1964) |
| " An overestimation of rare side-effects of drugs should not block the application of certain medicaments, however, they should be given only in such a high dosage as it is necessary." | 1.26 | [Hematotoxic lesions caused by non-steroidal antirheumatic agents]. ( Hüge, W; Stobbe, H, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| FELDMAN, L | 1 |
| COHNEN, F | 1 |
| HIRSCH, H | 1 |
| HARING, W | 1 |
| ESHOUGES, JR | 1 |
| GRIGUER, P | 1 |
| ARMSTRONG, FB | 1 |
| SCHERBEL, AL | 1 |
| NIEWEG, HO | 1 |
| BOUMA, HG | 1 |
| SOEPARMAN, R | 1 |
| ABELS, J | 1 |
| CROSBY, WH | 1 |
| KAUFMAN, RM | 1 |
| MCCARTHY, DD | 1 |
| CHALMERS, TM | 1 |
| BOEHM, C | 1 |
| Dunea, G | 1 |
| Muehrcke, RC | 1 |
| Nakamoto, S | 1 |
| Schwartz, FD | 1 |
| Baudo, F | 1 |
| Cipriani, D | 1 |
| De Cataldo, F | 1 |
| Ladelli, G | 1 |
| Pensabene, A | 1 |
| Bell, PM | 1 |
| Humphrey, CA | 1 |
| Watson, AD | 1 |
| Wilson, JT | 1 |
| Turner, DM | 1 |
| Culvenor, JA | 1 |
| Stobbe, H | 1 |
| Hüge, W | 1 |
| Tolot, F | 1 |
| Prost, G | 1 |
| Guignot, B | 1 |
| Pelletier, M | 1 |
| Engelmann, C | 1 |
| Tessenow, W | 1 |
| Dannenberg, C | 1 |
| Konrad, H | 1 |
| Huber, H | 1 |
| Michlmayr, G | 1 |
| Chaplin, S | 1 |
| Hadnagy, C | 1 |
| Macavei, I | 1 |
| Bornuz, F | 1 |
| Marinca, E | 1 |
| Sass, G | 1 |
| Rachmilewitz, M | 1 |
| Zbinden, G | 1 |
| Nenning, K | 1 |
| Turpie, AG | 1 |
| Chernesky, MA | 1 |
| Larke, RP | 1 |
| Packham, MA | 1 |
| Mustard, JF | 1 |
| Davidson, C | 1 |
| Manohitharajah, SM | 1 |
| Geary, CG | 1 |
| Dawson, DW | 1 |
| Sitlani, PK | 1 |
| Allison, HA | 1 |
| Leyland, MJ | 1 |
| Kimura, S | 1 |
| Shorota, N | 1 |
| Burns, SL | 1 |
| Lecomte, J | 1 |
3 reviews available for phenylbutazone and Thrombocytopenia
| Article | Year |
|---|---|
[Multiple manifestations of intolerance in association with anti-inflammatory agents. Role of phenylbutazone].
Topics: Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Drug Tolera | 1976 |
Bone marrow depression due to mianserin, phenylbutazone, oxyphenbutazone, and chloramphenicol--Part I.
Topics: Agranulocytosis; Anemia, Aplastic; Bone Marrow; Cell Membrane; Chloramphenicol; Dibenzazepines; DNA | 1986 |
Disorders of the blood in changing environmental conditions.
Topics: Agranulocytosis; Aminopyrine; Anemia, Aplastic; Anemia, Hemolytic; Anti-Bacterial Agents; Antibody F | 1970 |
24 other studies available for phenylbutazone and Thrombocytopenia
| Article | Year |
|---|---|
Fatal thrombocytopenic purpura following phenylbutazone (butazolidin) therapy.
Topics: Analgesics; Humans; Phenylbutazone; Purpura; Purpura, Thrombocytopenic; Thrombocytopenia | 1954 |
[Acute symptomatic thrombopenia after irgapyrin].
Topics: Aminopyrine; Analgesics; Blood Platelets; Drug Combinations; Phenylbutazone; Thrombocytopenia | 1955 |
[Acute fatal thrombopenic purpura with heterophil platelet agglutinins, after the absorption of pyramidon, five months after phenylbutazone treatment].
Topics: Agglutinins; Aminopyrine; Analgesics; Blood Platelets; Hemagglutination; Humans; Phenylbutazone; Pur | 1956 |
Review of toxicity of oxyphenbutazone, report of a case of thrombocytopenic purpura.
Topics: Humans; Oxyphenbutazone; Phenylbutazone; Purpura; Purpura, Thrombocytopenic; Thrombocytopenia | 1961 |
[CLINICAL STUDY ON CHANGES IN THE BLOOD CAUSED BY DRUGS].
Topics: Anemia; Anemia, Macrocytic; Anticonvulsants; Blood Platelet Disorders; Chloramphenicol; Chloroquine; | 1963 |
DRUG-INDUCED THROMBOCYTOPENIA.
Topics: Acetazolamide; Anticonvulsants; Arsphenamine; Chloramphenicol; Chlorothiazide; Colchicine; Gold; Hyd | 1964 |
HEMATOLOGICAL COMPLICATIONS OF PHENYLBUTAZONE THERAPY: REVIEW OF THE LITERATURE AND REPORT OF TWO CASES.
Topics: Adrenocorticotropic Hormone; Agranulocytosis; Anemia, Aplastic; Anemia, Macrocytic; Arthritis; Arthr | 1964 |
[ON HEMATOLOGIC SIDE-EFFECTS OF PHENYLBUTAZONE].
Topics: Agranulocytosis; Drug Hypersensitivity; Phenylbutazone; Thrombocytopenia; Toxicology | 1964 |
Thrombotic thrombocytopenic purpura with acute anuric renal failure.
Topics: Acute Kidney Injury; Adult; Anemia, Hemolytic; Anuria; Diagnosis, Differential; Female; Humans; Phen | 1966 |
[Coagulation disorders with comsumption of coagulation factors, probably due to drug hypersensitivity].
Topics: Adult; Afibrinogenemia; Blood Coagulation Disorders; Drug Hypersensitivity; Female; Hemorrhagic Diso | 1967 |
Thrombocytopenia and haemolytic anaemia due to feprazone.
Topics: Adult; Anemia, Hemolytic; Feprazone; Humans; Male; Muscle Cramp; Phenylbutazone; Thrombocytopenia | 1982 |
Phenylbutazone-induced blood dyscrasias suspected in three dogs.
Topics: Anemia; Animals; Dog Diseases; Dogs; Hematologic Diseases; Male; Pancytopenia; Phenylbutazone; Throm | 1980 |
[Hematotoxic lesions caused by non-steroidal antirheumatic agents].
Topics: Adult; Aged; Agranulocytosis; Anemia, Aplastic; Arthritis, Rheumatoid; Aspirin; Diclofenac; Female; | 1980 |
[Drug-induced].
Topics: Adult; Aged; Aminopyrine; Female; Glyburide; Humans; Male; Middle Aged; Phenacetin; Phenylbutazone; | 1976 |
[Drug induced cytopenias on immunological basis].
Topics: Antibody Formation; Chlorothiazide; Humans; Immunity, Cellular; Immunoglobulins; Phagocytosis; Pheny | 1975 |
[Bone marrow-damaging effect of various drugs].
Topics: Antitubercular Agents; Bone Marrow; Chloramphenicol; Drug Hypersensitivity; Drug Therapy, Combinatio | 1985 |
Modification of the fatty acid-induced thrombocytopenia by anticoagulants and compounds which inhibit in vitro platelet aggregation.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Anticoagulants; Bloo | 1968 |
[Drug-induced diseases of the mouth and jaw region].
Topics: Adult; Aged; Agranulocytosis; Aminopyrine; Antineoplastic Agents; Candidiasis, Oral; Dentin; Drug Hy | 1972 |
Effect of Newcastle disease virus on human or rabbit platelets. Aggregation and loss of constituents.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Blood Platelets; Chrom | 1973 |
Drug-induced antiplatelet antibodies.
Topics: Autoantibodies; Autoimmune Diseases; Blood Platelets; Female; Humans; Middle Aged; Phenylbutazone; T | 1973 |
An association between aplastic anaemia and sideroblastic anaemia.
Topics: Adult; Anemia, Aplastic; Anemia, Sideroblastic; Blood Cells; Bone Marrow; Bone Marrow Cells; Clone C | 1974 |
[A case report of massive bleeding from conjunctiva due to drug-induced thrombocytopenia].
Topics: Adult; Conjunctiva; Eye Diseases; Eye Injuries; Hemorrhage; Humans; Ketones; Male; Phenylbutazone; T | 1971 |
Anemia in rheumatoid arthritis.
Topics: Anemia; Arthritis, Rheumatoid; Chronic Disease; Female; Gastrointestinal Hemorrhage; Glucocorticoids | 1968 |
[On the anti-anaphylactic activity of pyrazolone derivatives in the rabbit].
Topics: Aminopyrine; Anaphylaxis; Animals; Antipyrine; Hypotension; Phenylbutazone; Rabbits; Thrombocytopeni | 1966 |