phenylbutazone has been researched along with Synovitis in 26 studies
Phenylbutazone: A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
phenylbutazone : A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.
Synovitis: Inflammation of the SYNOVIAL MEMBRANE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The eicosanoids, prostaglandin E2 (PGE2) and leukotriene B4, increased in synovial fluid after synovitis induction in all horses then returned to near baseline by 48 hours." | 9.08 | Effects of pretreatment with ketoprofen and phenylbutazone on experimentally induced synovitis in horses. ( Kamerling, SG; Keowen, ML; Owens, JG; Prescott-Mathews, JS; Stanton, SR, 1996) |
| "Although PBZ is clinically effective in treating acute synovitis, it does not limit inflammation-induced cartilage catabolism and may transiently reduce collagen anabolism as evidenced by SF markers." | 6.79 | In vivo effects of phenylbutazone on inflammation and cartilage-derived biomarkers in equine joints with acute synovitis. ( Brunott, A; de Grauw, JC; van de Lest, CH; van Loon, JP; van Weeren, PR, 2014) |
| "The eicosanoids, prostaglandin E2 (PGE2) and leukotriene B4, increased in synovial fluid after synovitis induction in all horses then returned to near baseline by 48 hours." | 5.08 | Effects of pretreatment with ketoprofen and phenylbutazone on experimentally induced synovitis in horses. ( Kamerling, SG; Keowen, ML; Owens, JG; Prescott-Mathews, JS; Stanton, SR, 1996) |
| "Although PBZ is clinically effective in treating acute synovitis, it does not limit inflammation-induced cartilage catabolism and may transiently reduce collagen anabolism as evidenced by SF markers." | 2.79 | In vivo effects of phenylbutazone on inflammation and cartilage-derived biomarkers in equine joints with acute synovitis. ( Brunott, A; de Grauw, JC; van de Lest, CH; van Loon, JP; van Weeren, PR, 2014) |
| "Acute synovitis was induced by intrasynovial injection of sodium urate crystals." | 1.29 | Vertical ground reaction force distribution during experimentally induced acute synovitis in dogs. ( Baird, DK; Goetze, LF; Kammermann, JR; Kincaid, SA; Rumph, PF; Visco, DM, 1993) |
| " In constrast, 3H-indometacin injected like ASA and PBZ in subtherapeutic dosage diappeared from the blood in a threephasic process." | 1.26 | [Antiphiogistic drugs. Sudies on the pharmocokinetics of anti-inflammatory agents]. ( Havemann, D, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (57.69) | 18.7374 |
| 1990's | 4 (15.38) | 18.2507 |
| 2000's | 3 (11.54) | 29.6817 |
| 2010's | 4 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Grauw, JC | 2 |
| van Loon, JP | 2 |
| van de Lest, CH | 1 |
| Brunott, A | 2 |
| van Weeren, PR | 2 |
| Banse, H | 1 |
| Cribb, AE | 1 |
| Weerts, EA | 1 |
| Stein, C | 1 |
| ROBECCHI, A | 1 |
| BIRESSI, PC | 1 |
| CARTASEGNA, F | 1 |
| HAMILTON, EJ | 1 |
| JESSAMINE, AG | 1 |
| EIDUS, L | 1 |
| Morton, AJ | 1 |
| Campbell, NB | 1 |
| Gayle, JM | 1 |
| Redding, WR | 1 |
| Blikslager, AT | 1 |
| Hewes, CA | 1 |
| Schneider, RK | 1 |
| Baszler, TV | 1 |
| Oaks, JL | 1 |
| Groves, L | 1 |
| Mozziconacci, P | 1 |
| Hayem, F | 1 |
| Guy-Grand, D | 1 |
| Dreher, R | 1 |
| Fink, K | 1 |
| Seidel, H | 1 |
| Wagner, P | 1 |
| Rohrbach, B | 1 |
| Federlin, K | 1 |
| Rumph, PF | 1 |
| Kincaid, SA | 1 |
| Baird, DK | 1 |
| Kammermann, JR | 1 |
| Visco, DM | 1 |
| Goetze, LF | 1 |
| Owens, JG | 1 |
| Kamerling, SG | 1 |
| Stanton, SR | 1 |
| Keowen, ML | 1 |
| Prescott-Mathews, JS | 1 |
| Havemann, D | 1 |
| Goldlust, MB | 1 |
| Rich, LC | 1 |
| Harrity, TW | 1 |
| Auer, DE | 1 |
| Ng, JC | 1 |
| Reilly, JS | 1 |
| Seawright, AA | 1 |
| Grau, M | 1 |
| Guasch, J | 1 |
| Montero, JL | 1 |
| Felipe, A | 1 |
| Carrasco, E | 1 |
| Juliá, S | 1 |
| Wepsic, HT | 1 |
| Hollingsworth, JW | 1 |
| Calabro, JJ | 1 |
| Katz, RM | 1 |
| Maltz, BA | 1 |
| Delbarre, F | 1 |
| Amor, B | 1 |
| Panahi, F | 1 |
| Mann, TS | 1 |
| Rosenthale, ME | 2 |
| Dervinis, A | 1 |
| Kassarich, J | 2 |
| Singer, S | 1 |
| Ellis, W | 1 |
| de Reus, HD | 1 |
| Lumachi, B | 1 |
| Schneider, F | 1 |
1 review available for phenylbutazone and Synovitis
| Article | Year |
|---|---|
A critical reappraisal of juvenile rheumatoid arthritis.
Topics: Agammaglobulinemia; Arthritis, Juvenile; Aspirin; Cardiomegaly; Child; Child, Preschool; Chloroquine | 1971 |
3 trials available for phenylbutazone and Synovitis
| Article | Year |
|---|---|
In vivo effects of phenylbutazone on inflammation and cartilage-derived biomarkers in equine joints with acute synovitis.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Collagen Type II | 2014 |
Upregulation of articular synovial membrane μ-opioid-like receptors in an acute equine synovitis model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthroscopy; Blotting, Western; Carpal Joints; Cro | 2013 |
Effects of pretreatment with ketoprofen and phenylbutazone on experimentally induced synovitis in horses.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Disease Models, Anima | 1996 |
22 other studies available for phenylbutazone and Synovitis
| Article | Year |
|---|---|
Comparative efficacy of oral meloxicam and phenylbutazone in 2 experimental pain models in the horse.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Horses; Lameness, Animal; Lipopolysacchari | 2017 |
Towards safer and more effective analgesia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Horse Diseases; Lameness, Animal; Male; Pain; Phen | 2013 |
[Changes induced by phenylbutazone therapy in the histological picture of acute gouty synovitis].
Topics: Gout; Humans; Phenylbutazone; Synovial Membrane; Synovitis | 1958 |
PSEUDOGOUT.
Topics: Adrenal Cortex Hormones; Calcification, Physiologic; Cartilage; Chondrocalcinosis; Crystallography; | 1964 |
Preferential and non-selective cyclooxygenase inhibitors reduce inflammation during lipopolysaccharide-induced synovitis.
Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme-Linked Immunosorb | 2005 |
Septic arthritis and granulomatous synovitis caused by infection with Mycobacterium avium complex in a horse.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Infectious; Diagnosis, Differential; Gr | 2005 |
Chip fractures from the distal lateral trochlear ridge of the talus of a quarter horse gelding: a veterinary medicine clinical report.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthroscopy; Combined Modality Therapy; Fractures, | 2005 |
[Chronic oligoarthritis in children].
Topics: Arthritis, Juvenile; Child; Child, Preschool; Chronic Disease; Female; Glucocorticoids; Humans; Hydr | 1967 |
[Immunomodulation by symptomaticly active antirheumatic agents].
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Autoradiography; Dexamethasone; Disease Models, Animal | 1983 |
Vertical ground reaction force distribution during experimentally induced acute synovitis in dogs.
Topics: Animals; Dog Diseases; Dogs; Female; Forelimb; Gait; Hindlimb; Male; Phenylbutazone; Stress, Mechani | 1993 |
[Antiphiogistic drugs. Sudies on the pharmocokinetics of anti-inflammatory agents].
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dexamethasone; Indomethacin; Injections, Intra-Articular | 1977 |
Effects of antiinflammatory agents on the acute response of immune synovitis in rabbits.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Colchicine; Disease Models, Animal; Dose-Response Relati | 1977 |
Anti-inflammatory drugs inhibit degradation of equine synovial fluid induced by free radicals.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dimethyl Sulfox | 1991 |
Pharmacology of the potent new non-steroidal anti-inflammatory agent aceclofenac.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Benzoquinones; Capillary | 1991 |
Effects of drugs on different types of synovial inflammation in the rabbit.
Topics: Animals; Antigen-Antibody Reactions; Arthus Reaction; Chloroquine; Cortisone; Endotoxins; Models, Bi | 1968 |
[Pelvic spondylarthritic involvement in Fiessinger-Leroy-Reiter rheumatism].
Topics: Adult; Arthritis; Arthritis, Reactive; Conjunctivitis; Cytoplasmic Granules; Humans; Indomethacin; I | 1969 |
Pseudogout.
Topics: Age Factors; Aged; Arthritis; Arthrography; Calcium; Calcium Phosphates; Chondrocalcinosis; Crystall | 1973 |
Prostaglandins and anti-inflammatory drugs in the dog knee joint.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dogs; Indomethacin; Inflammation; Knee Joint; Phenylbuta | 1972 |
Letter: Rubella arthritis.
Topics: Adult; Arthritis, Infectious; Carpal Tunnel Syndrome; Female; Humans; Leukocytes; Phenylbutazone; Ru | 1973 |
[Chondrocalcinosis ("pseudogout")].
Topics: Adrenal Cortex Hormones; Adult; Arthritis; Cartilage, Articular; Chondrocalcinosis; Chronic Disease; | 1974 |
Pharmacological investigations of 4-prenyl-1,2-diphenyl-3,5-pyrazolidinedione (DA 2370). 5. Activity on acute experimental synovitis in dogs.
Topics: Animals; Anti-Inflammatory Agents; Dogs; Female; Injections, Intra-Articular; Male; Phenylbutazone; | 1972 |
Effect of anti-inflammatory agents on acute experimental synovitis in dogs.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Chlorpromazine; Codeine; Dogs; Gout; Hydrocortisone; Ind | 1966 |