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phenylbutazone and Pleural Effusion

phenylbutazone has been researched along with Pleural Effusion in 16 studies

Phenylbutazone: A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
phenylbutazone : A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.

Pleural Effusion: Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself.

Research Excerpts

ExcerptRelevanceReference
"The action of phenylbutazone, a non-steroid anti-inflammatory drug, desonide, a corticosteroid, and cyclophosphamide, an immunosuppressant agent, was studied on four types of experimental pleurisy: carrageenan-pleurisy in rats; passive reversed Arthus pleurisy in rats; Bordetella pertussis-delayed hypersensitivity pleurisy in rats and PPD (purified protein derivative)--delayed hypersensitivity pleurisy in guinea-pigs."7.66Comparison of the effect of phenylbutazone, desonide and cyclophosphamide on four types of experimental pleurisy. ( Lauressergues, H; Tarayre, JP, 1980)
"The econazole pleurisy development is monophasic and its peak value occurs between 8 and 12 hr after econazole injection."5.27Some characteristics of econazole-induced pleurisy in rats. ( Hanada, S; Hirano, MT; Oga, S, 1985)
" The most potent compound synthesized, 1-(4-chlorophenyl)-3-isoquinolineacetamide, was as active as phenylbutazone in the Evans blue carrageenan-induced pleural effusion assay but inactive in the adjuvant-induced arthritis model of chronic inflammation."3.66Aroyl- and arylisoquinolineacetic acids as antiinflammatory agents. ( Reese, DL; Sancilio, LF; Walsh, DA, 1978)
"The action of phenylbutazone, a non-steroid anti-inflammatory drug, desonide, a corticosteroid, and cyclophosphamide, an immunosuppressant agent, was studied on four types of experimental pleurisy: carrageenan-pleurisy in rats; passive reversed Arthus pleurisy in rats; Bordetella pertussis-delayed hypersensitivity pleurisy in rats and PPD (purified protein derivative)--delayed hypersensitivity pleurisy in guinea-pigs."3.66Comparison of the effect of phenylbutazone, desonide and cyclophosphamide on four types of experimental pleurisy. ( Lauressergues, H; Tarayre, JP, 1980)
"The econazole pleurisy development is monophasic and its peak value occurs between 8 and 12 hr after econazole injection."1.27Some characteristics of econazole-induced pleurisy in rats. ( Hanada, S; Hirano, MT; Oga, S, 1985)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199016 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Welstead, WJ1
Moran, HW1
Stauffer, HF1
Turnbull, LB2
Sancilio, LF5
Walsh, DA1
Reese, DL1
Buckler, RT1
Hartzler, HE1
Kurchacova, E1
Nichols, G1
Phillips, BM1
TUGAN, B1
TUGSAVUL, K1
YALIN, M1
RIVERA LOPEZ, R1
LAZARO AMADOR, P1
PEDROTE GUINEA, JA1
PELUSO, E1
Birnie, JH1
Sutton, BM1
Zuccarello, M1
Rush, JA1
Tarayre, JP1
Lauressergues, H1
Schwarz, JA1
Jost, H1
Hanada, S1
Oga, S1
Hirano, MT1
Johnson, CP1
Chen, YH1
Bruce, RB1
Grosman, IuS1
Gel'dner, LB1
Bykova, AA1
Ortenberg, EA1
Pevzner, GI1
Baruffi, W1
Fadel, JC1
Rodriguez, R1

Other Studies

16 other studies available for phenylbutazone and Pleural Effusion

ArticleYear
Antiinflammatory agents. 1. Synthesis and antiinflammatory activity of 2-amino-3-benzoylphenylacetic acid.
    Journal of medicinal chemistry, 1979, Volume: 22, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Benzophenones; Biotransformation; Female

1979
Aroyl- and arylisoquinolineacetic acids as antiinflammatory agents.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Isoquinolines; Phenylbutazone; Pleural E

1978
Synthesis and antiinflammatory activity of some 1,2,3- and 1,2,4-triazolepropionic acids.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:12

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Male; Pleural Effusion; Propionates; Rat

1978
[Mixed treatment of tuberculosis exudative pleurisy with antibiotics & phenylbutazone].
    Bulletin international des services de sante des armees de terre, de mer et de l'air, 1957, Volume: 30, Issue:5

    Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Phenylbutazone; Pleural Effusion; Pleurisy; Tube

1957
[Tanderil in the treatment of post-thoracotomy effusions in mitral commissurotomy].
    Revista clinica espanola, 1963, Jun-15, Volume: 89

    Topics: Cardiac Surgical Procedures; Humans; Mitral Valve Stenosis; Oxyphenbutazone; Phenylbutazone; Pleural

1963
[THERAPEUTIC EFFECTS OF A METABOLITE OF PHENYLBUTAZONE (G 27202) IN PRIMARY SEROSITIS].
    La Clinica terapeutica, 1964, Apr-15, Volume: 29

    Topics: Aminopyrine; Blood Sedimentation; Humans; Isoniazid; Neoplasms; Oxyphenbutazone; Peritonitis; Perito

1964
Some anti-inflammatory properties of 8-trifluoromethylphenothiazine-1-carboxylic acid (SK & F 22908).
    Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1967, Volume: 17, Issue:1

    Topics: Animals; Erythema; Flufenamic Acid; Granuloma; Guinea Pigs; Indomethacin; Male; Phenothiazines; Phen

1967
Comparison of the effect of phenylbutazone, desonide and cyclophosphamide on four types of experimental pleurisy.
    The Journal of pharmacy and pharmacology, 1980, Volume: 32, Issue:6

    Topics: Animals; Cyclophosphamide; Desonide; Edema; Female; Guinea Pigs; Leukocytes; Male; Neutrophils; Phen

1980
[Pseudo-LE syndrome after treatment with Venopyronum dragees] (author's transl)
    Deutsche medizinische Wochenschrift (1946), 1975, Aug-01, Volume: 100, Issue:31

    Topics: Adult; Autoantibodies; Autoimmune Diseases; Diagnosis, Differential; Female; Fever; Fluorescent Anti

1975
Some characteristics of econazole-induced pleurisy in rats.
    General pharmacology, 1985, Volume: 16, Issue:6

    Topics: Animals; Carrageenan; Chlorpheniramine; Cyproheptadine; Dexamethasone; Econazole; Imidazoles; Inflam

1985
Disposition and metabolism of 4-methyl-2(4-phenylbenzyl)-2-oxazoline-4-methanol in the rat and dog.
    Journal of medicinal chemistry, 1974, Volume: 17, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Autoradiography; Biphenyl Compounds; Carbon Radioisotopes; Carrag

1974
[Effect of hydrocortisone and butadion on the distribution of kanamycin in experimental pleuritis].
    Biulleten' eksperimental'noi biologii i meditsiny, 1970, Volume: 70, Issue:12

    Topics: Animals; Female; Hydrocortisone; Kanamycin; Lung; Male; Phenylbutazone; Pleural Effusion; Pleurisy;

1970
[Exudation into the pleural cavity in the use of butadion].
    Klinicheskaia meditsina, 1967, Volume: 45, Issue:5

    Topics: Drug Hypersensitivity; Female; Humans; Middle Aged; Phenylbutazone; Pleural Effusion

1967
Evans blue-carrageenan pleural effusion as a model for the assay of nonsteroidal antirheumatic drugs.
    The Journal of pharmacology and experimental therapeutics, 1969, Volume: 168, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Carrageenan; Chloroquine; Coloring Agents; Ed

1969
[Treatment of pleural effusions in hospitalized tuberculous patients with phenylbutazone. Observations on 5 cases. Preliminary note].
    Folha medica, 1965, Volume: 50, Issue:5

    Topics: Phenylbutazone; Pleural Effusion; Tuberculosis, Pulmonary

1965
Effect of non-steroidal anti-inflammatory drugs in the Evans Blue pleural effusion.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1966, Volume: 123, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Coloring Agents; Flufenamic Acid; Indomethacin; Mefenami

1966