phenylbutazone has been researched along with Necrosis in 26 studies
Phenylbutazone: A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
phenylbutazone : A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenylbutazone (PBZ) toxicosis was induced in 9 ponies to further define the clinical and pathologic changes occurring with this syndrome." | 7.67 | Experimentally induced phenylbutazone toxicosis in ponies: description of the syndrome and its prevention with synthetic prostaglandin E2. ( Collins, LG; Tyler, DE, 1985) |
| "A case is reported of a male adult with Haemophilus influenzae type b septicaemia and subsequent abscess in the left thigh due to this microorganism following injection of phenylbutazone." | 3.67 | Haemophilus influenzae type b septicaemia associated with myonecrosis and thigh abscess. ( Grehn, M; Gurtner, B; Hartmann, D; Vontobel, H, 1988) |
| "Phenylbutazone (PBZ) toxicosis was induced in 9 ponies to further define the clinical and pathologic changes occurring with this syndrome." | 3.67 | Experimentally induced phenylbutazone toxicosis in ponies: description of the syndrome and its prevention with synthetic prostaglandin E2. ( Collins, LG; Tyler, DE, 1985) |
| "Phenylbutazone-treated horses had a significant (P < 0." | 1.29 | Comparison of adverse effects of phenylbutazone, flunixin meglumine, and ketoprofen in horses. ( Borne, AT; MacAllister, CG; Morgan, SJ; Pollet, RA, 1993) |
| "Phenylbutazone was administered at a dosage of 10 mg/kg of bodyweight (BW) per day, intravenously (IV), in equally divided doses to three of the groups." | 1.28 | The protective effects of sucralfate and ranitidine in foals experimentally intoxicated with phenylbutazone. ( Geor, RJ; Papich, MG; Petrie, L; Rousseaux, C, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (92.31) | 18.7374 |
| 1990's | 2 (7.69) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MIZUSHIMA, Y | 1 |
| MACCARTHY, JM | 1 |
| JACKSON, RT | 1 |
| KEUSTERS, E | 1 |
| Littmann, K | 1 |
| Albrecht, KH | 1 |
| Richter, HJ | 1 |
| Eigler, FW | 1 |
| Owen, RA | 1 |
| Heywood, R | 1 |
| Rerábková, L | 1 |
| Künzi, T | 1 |
| Ramstein, C | 1 |
| Pirovino, M | 1 |
| MacAllister, CG | 1 |
| Morgan, SJ | 1 |
| Borne, AT | 1 |
| Pollet, RA | 1 |
| Brachtel, R | 2 |
| Meinertz, T | 1 |
| Freilinger, G | 1 |
| Schürer-Waldheim, H | 1 |
| Geor, RJ | 1 |
| Petrie, L | 1 |
| Papich, MG | 1 |
| Rousseaux, C | 1 |
| Hartmann, D | 1 |
| Grehn, M | 1 |
| Vontobel, H | 1 |
| Gurtner, B | 1 |
| Altmann, HW | 1 |
| Collins, LG | 1 |
| Tyler, DE | 1 |
| Reinisch, H | 1 |
| Lombardino, JG | 1 |
| Wiseman, EH | 1 |
| Nenning, K | 1 |
| Arnold, L | 1 |
| Collins, C | 1 |
| Starmer, GA | 1 |
| Stabenow, DL | 1 |
| Müller, E | 1 |
| Löhr, E | 1 |
| Tritsch, H | 1 |
| Hartveit, F | 1 |
| Halleraker, B | 1 |
| Bowers, J | 1 |
| Arnold, IL | 1 |
| Wajcner, G | 1 |
| Guedon, J | 1 |
| Chapman, A | 1 |
| Catterall, RD | 1 |
2 reviews available for phenylbutazone and Necrosis
| Article | Year |
|---|---|
[INFLAMMATION, RHEUMATISM, ALLERGY, AND ANTI-INFLAMMATORY AGENTS AT THE MOLECULAR LEVEL].
Topics: Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Antigen-Antibody Reactions; Antipyre | 1964 |
[Skin embolism. Etiology, clinical aspects, therapy and prevention].
Topics: Adult; Back Pain; Buttocks; Embolism; Female; Humans; Injections, Intramuscular; Male; Middle Aged; | 1984 |
24 other studies available for phenylbutazone and Necrosis
| Article | Year |
|---|---|
Hepatic necrosis and other visceral lesions associated with phenylbutazone therapy.
Topics: Analgesics; Arthritis; Arthritis, Rheumatoid; Humans; Kidney; Liver; Necrosis; Phenylbutazone | 1955 |
[Necrotic pupura after butazolidine].
Topics: Animals; Gastropoda; Necrosis; Phenylbutazone; Purpura | 1961 |
Phenylbutazone-induced nephrotoxicity in the rat.
Topics: Animals; Body Weight; Hydrogen-Ion Concentration; Kidney; Male; Necrosis; Organ Size; Phenylbutazone | 1983 |
[Damage to skeletal muscles by intramuscular administration of anti-inflammatory agents of the pyrazolidine type].
Topics: Animals; Anti-Inflammatory Agents; Drug Combinations; Injections, Intramuscular; Male; Muscles; Necr | 1983 |
[Circumscribed skin necrosis following intramuscular injection (embolia cutis medicamentosa)].
Topics: Aged; Aged, 80 and over; Female; Glucocorticoids; Humans; Injections, Intramuscular; Male; Middle Ag | 1995 |
Comparison of adverse effects of phenylbutazone, flunixin meglumine, and ketoprofen in horses.
Topics: Animals; Anorexia; Blood Proteins; Clonixin; Female; Gastric Mucosa; Gastroscopy; Horse Diseases; Ho | 1993 |
Local skin necroses after intramuscular injection -Experimental animal studies-.
Topics: Animals; Blood Vessels; Dermatitis, Contact; Female; Injections, Intramuscular; Male; Necrosis; Phen | 1977 |
[Iatrogenic tissue damage and its treatment (author's transl)].
Topics: Bone Nails; Coumarins; Dicloxacillin; Electrosurgery; Humans; Iatrogenic Disease; Necrosis; Phenylbu | 1976 |
[Embolia cutis medicamentosa (author's transl)].
Topics: Adult; Aged; Anti-Inflammatory Agents; Buttocks; Embolism; Humans; Injections, Intramuscular; Male; | 1976 |
The protective effects of sucralfate and ranitidine in foals experimentally intoxicated with phenylbutazone.
Topics: Animals; Animals, Newborn; Blood Chemical Analysis; Digestive System Diseases; Duodenum; Hematologic | 1989 |
Haemophilus influenzae type b septicaemia associated with myonecrosis and thigh abscess.
Topics: Abscess; Adult; Haemophilus Infections; Haemophilus influenzae; Humans; Injections, Intramuscular; M | 1988 |
Morphological changes in the liver due to phenazone and its derivatives.
Topics: Antipyrine; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Fatty Liver; Granulom | 1986 |
Experimentally induced phenylbutazone toxicosis in ponies: description of the syndrome and its prevention with synthetic prostaglandin E2.
Topics: Animals; Dinoprostone; Female; Gastrointestinal Diseases; Horse Diseases; Horses; Intestinal Mucosa; | 1985 |
[Death by sepsis after treatment of butazolidin].
Topics: Adult; Aged; Buttocks; Female; Hematoma; Hemorrhage; Humans; Ileum; Injections, Intramuscular; Intes | 1970 |
Preparation and antiinflammatory activity of some nonacidic trisubstituted imidazoles.
Topics: Administration, Oral; Adrenal Glands; Adrenalectomy; Animals; Anti-Inflammatory Agents; Carrageenan; | 1974 |
[Drug-induced diseases of the mouth and jaw region].
Topics: Adult; Aged; Agranulocytosis; Aminopyrine; Antineoplastic Agents; Candidiasis, Oral; Dentin; Drug Hy | 1972 |
Renal and gastric lesions after phenylbutazone and indomethacin in the rat.
Topics: Animals; Ascites; Epithelium; Female; Gastrointestinal Hemorrhage; Indomethacin; Kidney; Kidney Papi | 1974 |
Toxic epidermal necrolysis.
Topics: Adult; Age Factors; Child, Preschool; Erythromycin; Humans; Infant; Infant, Newborn; Necrosis; Penic | 1972 |
[Uric arthritis of the hip joint. Differential diagnosis of the idiopathic femur head necrosis].
Topics: Adult; Diagnosis, Differential; Femur Head; Gout; Hip Joint; Humans; Male; Necrosis; Phenylbutazone; | 1969 |
[Necrolysis as an histopathological phenomenon].
Topics: Exanthema; Humans; Necrosis; Penicillins; Phenylbutazone; Skin Tests; Stevens-Johnson Syndrome | 1970 |
Changes in the connective tissue and inflammatory response to Ehrlich's carcinoma following treatment of the host mice with butazolidine.
Topics: Animals; Capillaries; Carcinoma, Ehrlich Tumor; Connective Tissue; Female; Inflammation; Leukocytes; | 1970 |
Necrotizing scleral degeneration treated with a graft of autogenous fascia lata.
Topics: Aged; Conjunctiva; Eye Diseases; Fascia; Female; Humans; Necrosis; Panophthalmitis; Phenylbutazone; | 1970 |
[Acute anuric renal insufficiency with necrosing arteriolitis. Etiologic problems].
Topics: Acute Kidney Injury; Adult; Anemia, Hemolytic; Angioedema; Anuria; Arteritis; Arthritis; Aspirin; Dr | 1968 |
Fatal reaction to phenylbutazone in a patient with Reiter's disease.
Topics: Adult; Arthritis, Reactive; Chemical and Drug Induced Liver Injury; Humans; Jaundice; Liver; Male; N | 1968 |