phenylbutazone has been researched along with Myotonic Dystrophy in 2 studies
Phenylbutazone: A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
phenylbutazone : A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.
Myotonic Dystrophy: Neuromuscular disorder characterized by PROGRESSIVE MUSCULAR ATROPHY; MYOTONIA, and various multisystem atrophies. Mild INTELLECTUAL DISABILITY may also occur. Abnormal TRINUCLEOTIDE REPEAT EXPANSION in the 3' UNTRANSLATED REGIONS of DMPK PROTEIN gene is associated with Myotonic Dystrophy 1. DNA REPEAT EXPANSION of zinc finger protein-9 gene intron is associated with Myotonic Dystrophy 2.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, K | 1 |
| Masuda, A | 2 |
| Chen, G | 2 |
| Bushra, S | 1 |
| Kamon, M | 1 |
| Araki, T | 1 |
| Kinoshita, M | 2 |
| Ohkawara, B | 2 |
| Ito, M | 2 |
| Ohno, K | 2 |
| Konishi, H | 1 |
| Kiyama, H | 1 |
| Matsuura, T | 1 |
2 other studies available for phenylbutazone and Myotonic Dystrophy
| Article | Year |
|---|---|
Inhibition of cyclooxygenase-1 by nonsteroidal anti-inflammatory drugs demethylates MeR2 enhancer and promotes Mbnl1 transcription in myogenic cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; CELF1 Protein; Cyclooxygenase 1; Cyclooxygenase 2; | 2020 |
Phenylbutazone induces expression of MBNL1 and suppresses formation of MBNL1-CUG RNA foci in a mouse model of myotonic dystrophy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Disease Models, Animal; DNA-Binding Pro | 2016 |