phenylbutazone has been researched along with Muscle Contraction in 24 studies
Phenylbutazone: A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
phenylbutazone : A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Different mechanisms are involved in drug interactions, especially between anesthetics and drug administrated before and during anesthesia: liver disease, bioavailability related to the route of administration, displacement of the protein-bound of the part, etc." | 1.26 | [Veterinary anesthesiology, a pharmacological model (author's transl)]. ( Richez, P; Ruckebusch, Y, 1980) |
| " Thiazolinobutazone was the less toxic (acute LD50) and the less ulcerogenic molecule of the two and, in contrast to phenylbutazone, was not antidiuretic." | 1.26 | Pharmacological properties of thiazolinobutazone (LAS 11 871). III. General pharmacology, ulcerogenic effects and acute toxicity. ( Colombo, M; Márquez, M; Roberts, DJ, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (95.83) | 18.7374 |
| 1990's | 1 (4.17) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Feigen, GA | 1 |
| Sanz, E | 1 |
| Alender, CB | 1 |
| Kirk, RM | 1 |
| Mersereau, WA | 1 |
| Hinchey, EJ | 1 |
| Ruckebusch, Y | 1 |
| Richez, P | 1 |
| Van Hoogmoed, L | 1 |
| Rakestraw, PC | 1 |
| Snyder, JR | 1 |
| Harmon, FA | 1 |
| Van Nueten, JM | 1 |
| Guyonnet, JC | 1 |
| Julou, L | 1 |
| Colombo, M | 1 |
| Márquez, M | 1 |
| Roberts, DJ | 1 |
| Niemegeers, CJ | 1 |
| Van Bruggen, JA | 1 |
| Janssen, PA | 1 |
| Tsai, CS | 1 |
| Ochillo, RF | 1 |
| Fjalland, B | 1 |
| Ferreira, SH | 1 |
| Vargaftig, BB | 2 |
| Burka, JF | 1 |
| Eyre, P | 1 |
| Weidler, DJ | 1 |
| Diecke, FP | 1 |
| Görög, P | 1 |
| Kovàcs, IB | 1 |
| LeDouarec, JC | 1 |
| Duhault, J | 1 |
| Laubie, M | 1 |
| Tubaro, E | 1 |
| Bulgini, MJ | 1 |
| Del Grande, P | 1 |
| Monai, A | 1 |
| Dao, N | 1 |
| Tsurumi, K | 3 |
| Hayashi, M | 3 |
| Nakano, K | 2 |
| Go, K | 1 |
| Fujimura, H | 2 |
| Abe, A | 1 |
| Caprino, L | 1 |
| Borrelli, F | 1 |
| Falchetti, R | 1 |
| Hiramatsu, Y | 1 |
| Nozaki, M | 1 |
| Shibuya, T | 1 |
| Helfer, H | 1 |
| Jaques, R | 1 |
| Iorio, LC | 1 |
| Constantine, JW | 1 |
24 other studies available for phenylbutazone and Muscle Contraction
| Article | Year |
|---|---|
Studies on the mode of action of sea urchin toxin. I. Conditions affecting release of hiamine and other agents from isolated tissues.
Topics: Animals; Atropine; Blood Flow Velocity; Carbon; Chemical Precipitation; Chemistry Techniques, Analyt | 1966 |
Factors determining the site of chronic gastroduodenal ulcers.
Topics: Animals; Aspirin; Chronic Disease; Diet; Digestive System; Duodenum; Gastric Acid; Gastric Mucins; G | 1982 |
Prevention of phenylbutazone ulcer in the rat by glucose: role of a glycoprivic receptor system.
Topics: Animals; Female; Fructose; Gastrointestinal Hemorrhage; Glucose; Mannitol; Muscle Contraction; Pheny | 1982 |
[Veterinary anesthesiology, a pharmacological model (author's transl)].
Topics: Anesthesia; Animals; Biological Availability; Blood Proteins; Body Temperature; Cats; Chloramphenico | 1980 |
In vitro effects of nonsteroidal anti-inflammatory agents and prostaglandins I2, E2, and F2alpha on contractility of taenia of the large colon of horses.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Clonixin; Colon; Cyclooxygenase Inhibi | 1999 |
Antagonism of arachidonic acid hydroperoxide on isolated gastrointestinal tissues as a measure of the inhibition of prostaglandin biosynthesis.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Biolog | 1976 |
Relationship between the inhibitory activity on 'RCS' and prostaglandins synthesis and the anti-inflammatory activity of ketoprofen and several other non-steroidal anti-inflammatory agents.
Topics: Abscess; Animals; Anti-Inflammatory Agents; Aorta; Arachidonic Acids; Aspirin; Benzophenones; Colon; | 1976 |
Pharmacological properties of thiazolinobutazone (LAS 11 871). III. General pharmacology, ulcerogenic effects and acute toxicity.
Topics: Animals; Autonomic Nervous System; Brain; Cats; Diuresis; Female; Hemodynamics; Lethal Dose 50; Male | 1976 |
Suprofen, a potent antagonist of acetic acid-induced writhing in rats.
Topics: Acetates; Analgesics; Animals; Arachidonic Acids; Aspirin; Dose-Response Relationship, Drug; Drug Ev | 1975 |
The effects of phenylbutazone on acetylcholine-initiated contractions of gastric muscularis muscle of Bufo marinus.
Topics: Acetylcholine; Animals; Bufo marinus; Dinoprostone; Female; In Vitro Techniques; Male; Muscle Contra | 1987 |
Inhibition by non-steroidal anti-inflammatory agents of the release of rabbit aorta contracting substance and prostaglandins from chopped guinea-pig lungs.
Topics: Animals; Anti-Inflammatory Agents; Aorta; Aspirin; Female; Flufenamic Acid; Guinea Pigs; In Vitro Te | 1974 |
Inhibition by non-steroid anti-inflammatory agents of rabbit aorta contracting activity generated in blood by slow reacting substance C.
Topics: Animals; Anti-Inflammatory Agents; Aorta; Arachidonic Acids; Atropine; Autacoids; Colon; Dogs; Fatty | 1974 |
Studies of prostaglandins and prostaglandin antagonists on bovine pulmonary vein in vitro.
Topics: Acetylcholine; Animals; Aspirin; Bradykinin; Cattle; Depression, Chemical; Diethylcarbamazine; Dose- | 1974 |
The effect of several non-narcotic analgesics on a skeletal muscle receptor.
Topics: Amino Alcohols; Analgesics; Animals; Anura; Aspirin; Dextropropoxyphene; Muscle Contraction; Muscle | 1968 |
Effect of anti-inflammatory compounds on actomyosin-adenosinetriphosphate interaction.
Topics: Actomyosin; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; As | 1970 |
[Pharmacological study of phenethyl-8-oxa-1-diaza-3,8-spiro(4,5)decanone-2 hydrochloride or fenspiride (JP 428)].
Topics: Anaphylaxis; Anesthesia; Animals; Anti-Inflammatory Agents; Atropine; Autonomic Nervous System; Bron | 1969 |
Some toxicological aspects of a nicotinamide-methylaminopyrazolone (Ra 101).
Topics: Abnormalities, Drug-Induced; Acetylcholine; Aminopyrine; Analgesics; Animals; Aspirin; Blood; Blood | 1970 |
Release of vasoactive substances from guinea-pig lungs by slow-reacting substance c and arachidonic acid. Its blockade by nonsteroid anti-inflammatory agents.
Topics: Adenosine Triphosphate; Anaphylaxis; Animals; Aorta; Arachidonic Acids; Aspirin; Autacoids; Blood Ve | 1971 |
[Pharmacological studies of niflumic acid, with special reference to the comparison with fenamates. 2. General pharmacological effects].
Topics: Aniline Compounds; Animals; Body Temperature; Digestive System; Electric Stimulation; Electrocardiog | 1972 |
[Pharmacological studies of N-benzoyl-N'-phenyl-2,6-diaminobenzoic acid (F-1). 2. General pharmacology].
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antitussive Agents; Aspirin; Benzoates; Blood Coagula | 1973 |
General pharmacological properties of 4,5-diphenyl-2-bis-(2-hydroxyethyl)-aminoxazol (ditazol).
Topics: Amphetamine; Animals; Anti-Inflammatory Agents; Atropine; Blood Pressure; Cats; Chlorpromazine; Etha | 1973 |
[Anti-inflammatory action of N-(2,6-dichlorophenyl)-o-aminophenylacetic acid, its sodium salt, N-(2,6-dichlorophenyl)-anthranilic acid and its sodium salt. 1. On acute inflammation].
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Capillary Permeability; Edema; Electrolytes; Eryth | 1973 |
Vasotropic activity of arachidonic acid peroxide on the isolated murine portal vein and its modification by antiinflammatory substances.
Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Arachidonic Acids; Benzyl Compounds; Blood Vessels; | 1974 |
Bradykinin on isolated guinea-pig tracheal muscle.
Topics: Acetylcholine; Animals; Bradykinin; Guinea Pigs; Hypoxia; Muscle Contraction; Muscle, Smooth; Phenyl | 1969 |