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phenylbutazone and Lupus Erythematosus, Systemic

phenylbutazone has been researched along with Lupus Erythematosus, Systemic in 38 studies

Phenylbutazone: A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
phenylbutazone : A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.

Lupus Erythematosus, Systemic: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.

Research Excerpts

ExcerptRelevanceReference
"23 patients with proven pseudolupus-syndrome were observed over a period of five years; titers of specific antimitochondrial antibodies (AMA) were tested in a follow-up study after the last intake of Venopyronum-Dragees (VPD), a drug combination of plant glycosides, horse-chestnut extracts and phenopyrazone."3.66[Immune reactions in pseudo-lupus-syndrome. A long-term study (author's transl)]. ( Berg, PA; Schuff-Werner, P, 1980)
"Though there are analogies to the systemic lupus erythematosus, we must take into consideration a diversity of diseases."1.27[Drug-induced lupus erythematosus syndrome. Pathogenesis and relation to systemic lupus erythematosus]. ( Wollina, U, 1984)
"As opposed to Systemic Lupus Erythematosus hypertension did not occur in a higher frequency than normal."1.26[A contribution to the pseudo-LE-syndrome. Investigations of the cardiovascular system, abdominal organs, lymphatic system and drug histories (author's transl)]. ( Beltz, L; Flenker, I; Genth, E; Hermanutz, H; Rohner, HG; Senekamp, J; Wagner, J, 1976)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199038 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
LANGHOF, H1
GONCALVES, GW1
IRBY, R1
VACHTENHEIM, J1
DENKO, CW1
DAVIS, LP1
CARPENTER, RR1
GOODMAN, HC1
Kantor, TG1
Hofmeister, A2
Wollina, U1
Schuff-Werner, P1
Berg, PA1
Grob, PJ1
Müller-Schoop, JW1
Häcki, MA1
Joller-Jemelka, HI1
Maintz, J1
Henningsen, B1
Buchholz, K1
Harders, H1
Gadzhiev, RG1
Davardarova, MM1
Walden, PA1
Philalithis, PE1
Joekes, AM1
Bagshawe, KD1
Ricken, D1
Flenker, I2
Sack, KE1
Rosenthal, SH1
Senekamp, J1
Genth, E3
Hermanutz, H1
Wagner, J1
Beltz, L1
Rohner, HG1
Stenzel, K1
Brude, E1
Hartl, W1
Schwarz, JA1
Jost, H1
Furey, JG1
Maas, D1
Schubothe, H1
Sennekamp, J1
Maerker-Alzer, G1
Droese, M1
Hartl, PW1
Schumacher, K1
Farid, N1
Anderson, J1
Scheiffarth, F1
Calabro, JJ1
Katz, RM1
Maltz, BA1
Suţeanu, S1
Ciobanu, V1
Stroescu, O1
Georgescu, C1
Popescu, E1
Cosh, JA1
Emmrich, R1
Eberl, R1
Altmann, H1
Klein, W1
Marmont, A1
Rossi, F1
Boone, JE1
Baldwin, J1
Levine, C1
Ammitzboll, F1
Lang, H1
Anttila, R1
Svékus, A1
Laaksonen, AL1
Dubois, EL1
Burns, SL1
Join, F1
Tremblay, F1
Saito, T1
Sugai, T1
Aoki, K1

Reviews

3 reviews available for phenylbutazone and Lupus Erythematosus, Systemic

ArticleYear
Rheumatoid arthritis: an overview.
    Texas medicine, 1976, Volume: 72, Issue:11

    Topics: Adult; Arthritis; Arthritis, Reactive; Arthritis, Rheumatoid; Aspirin; Diagnosis, Differential; Fema

1976
A critical reappraisal of juvenile rheumatoid arthritis.
    Clinical orthopaedics and related research, 1971, Volume: 74

    Topics: Agammaglobulinemia; Arthritis, Juvenile; Aspirin; Cardiomegaly; Child; Child, Preschool; Chloroquine

1971
Juvenile rheumatoid arthritis.
    Pediatric clinics of North America, 1974, Volume: 21, Issue:4

    Topics: Antibodies, Antinuclear; Antimalarials; Arthritis, Juvenile; Aspirin; Blood Sedimentation; Child; Co

1974

Trials

1 trial available for phenylbutazone and Lupus Erythematosus, Systemic

ArticleYear
[Clinical study with a new phenylbutazone preparation in rheumatology].
    La Clinica terapeutica, 1972, Oct-15, Volume: 63, Issue:1

    Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Dermatomyositis; Drug Tolerance; Evaluation Studies

1972

Other Studies

34 other studies available for phenylbutazone and Lupus Erythematosus, Systemic

ArticleYear
[Target therapy of the vascular injury in subacute lupus erythematosus with irgapyrin].
    Dermatologische Wochenschrift, 1953, Volume: 128, Issue:36

    Topics: Aminopyrine; Analgesics; Capillaries; Disease; Drug Combinations; Humans; Lupus Erythematosus, Syste

1953
[G 27,202 in various rheumatic diseases].
    Hospital (Rio de Janeiro, Brazil), 1962, Volume: 61

    Topics: Arthritis; Arthritis, Rheumatoid; Humans; Lupus Erythematosus, Systemic; Periarthritis; Phenylbutazo

1962
Anti-inflammatory agents in the treatment of connective tissue diseases.
    Virginia medical monthly, 1963, Volume: 90

    Topics: Adrenal Cortex Hormones; Arthritis; Arthritis, Rheumatoid; Aspirin; Chloroquine; Humans; Lupus Eryth

1963
[PROVOCATING FACTORS IN SYSTEMIC LUPUS ERYTHEMATOSUS (WITH REFERENCE TO THERAPEUTIC AGENTS)].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1963, Sep-15, Volume: 18

    Topics: Anticonvulsants; Antitubercular Agents; Autoimmune Diseases; Drug Hypersensitivity; Drug Therapy; Go

1963
A CORRELATIVE CLINICOPATHOLOGICAL STUDY OF SYSTEMIC LUPUS ERYTHEMATOSUS IN FORTY-THREE PATIENTS.
    Archives of interamerican rheumatology : A.I.R, 1964, Volume: 7

    Topics: Adrenal Cortex Hormones; Antimalarials; Black People; Demography; Endocarditis; Geriatrics; Kidney;

1964
THERAPY OF DISEASES ASSOCIATED WITH ABNORMAL IMMUNE MECHANISMS.
    Diseases of the chest, 1965, Volume: 47

    Topics: Adrenal Cortex Hormones; Antigen-Antibody Reactions; Antineoplastic Agents; Arthritis; Arthritis, Rh

1965
Medical management of patients with disability due to arthritis.
    Archives of physical medicine and rehabilitation, 1967, Volume: 48, Issue:3

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anti-Bacterial Agents; Antimalarials; Arthritis, I

1967
[What is a pseudo-LE-syndrome?].
    Die Medizinische Welt, 1983, Dec-02, Volume: 34, Issue:48

    Topics: Antibodies, Antinuclear; Autoantibodies; Drug Combinations; Female; Glycosides; Humans; Lupus Erythe

1983
[Drug-induced lupus erythematosus syndrome. Pathogenesis and relation to systemic lupus erythematosus].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1984, Mar-01, Volume: 39, Issue:5

    Topics: Diagnosis, Differential; Drug-Related Side Effects and Adverse Reactions; Humans; Hydralazine; Lupus

1984
[Immune reactions in pseudo-lupus-syndrome. A long-term study (author's transl)].
    Klinische Wochenschrift, 1980, Sep-15, Volume: 58, Issue:18

    Topics: Antibodies; Drug Combinations; Glycosides; Humans; Immunity, Cellular; Lupus Erythematosus, Systemic

1980
Drug-induced pseudolupus.
    Lancet (London, England), 1975, Jul-26, Volume: 2, Issue:7926

    Topics: Antibodies; Cardiac Glycosides; Drug Combinations; Humans; Immune Adherence Reaction; Immunity, Cell

1975
[Unusual clinical forms of pseudo-LE syndrome: an induced immune-complex disease? (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1975, Jul-25, Volume: 100, Issue:30

    Topics: Adult; Aged; Antibodies; Bone Marrow Diseases; Female; Humans; Immune Complex Diseases; Lupus Erythe

1975
[Effectiveness of butadione ointment in some dermatoses].
    Vestnik dermatologii i venerologii, 1975, Issue:8

    Topics: Acne Vulgaris; Adolescent; Adult; Aged; Child; Dermatitis; Drug Eruptions; Drug Evaluation; Eczema;

1975
[The lupus erythematosus visceralis syndrome].
    Medizinische Klinik, 1979, Jul-13, Volume: 74, Issue:28-29

    Topics: Dosage Forms; Humans; Iatrogenic Disease; Lupus Erythematosus, Systemic; Phenylbutazone; Syndrome

1979
Development of a lymphocytic lymphoma during immunosuppressive therapy with azathioprine for systemic lupus erythematosus with renal involvement induced by phenylbutazone.
    Clinical nephrology, 1977, Volume: 8, Issue:1

    Topics: Azathioprine; Female; Humans; Kidney Diseases; Lupus Erythematosus, Systemic; Lymphoma, Non-Hodgkin;

1977
[Therapy of systemic lupus erythematosus and of pseudo-le-syndrome].
    Deutsche medizinische Wochenschrift (1946), 1978, Nov-17, Volume: 103, Issue:46

    Topics: Aged; Azathioprine; Chloroquine; Cyclophosphamide; Diagnosis, Differential; Female; Glucocorticoids;

1978
[A contribution to the pseudo-LE-syndrome. Investigations of the cardiovascular system, abdominal organs, lymphatic system and drug histories (author's transl)].
    Klinische Wochenschrift, 1976, Aug-15, Volume: 54, Issue:16

    Topics: Adult; Aged; Autoantibodies; Cardiac Catheterization; Female; Heart Diseases; Heart Failure; Humans;

1976
[Detection of antimitochondrial antibodies in guinea pigs after oral application of Venopyronum tablets. Radioimmunoassay of antimitochondrial antibodies of the pseudo-lupus-erythematosus type, preliminary communication (proceedings)].
    Immunitat und Infektion, 1976, Volume: 4, Issue:5

    Topics: Administration, Oral; Animals; Antibody Specificity; Autoantibodies; Guinea Pigs; Lupus Erythematosu

1976
[Pseudo-LE syndrome after treatment with Venopyronum dragees] (author's transl)
    Deutsche medizinische Wochenschrift (1946), 1975, Aug-01, Volume: 100, Issue:31

    Topics: Adult; Autoantibodies; Autoimmune Diseases; Diagnosis, Differential; Female; Fever; Fluorescent Anti

1975
Plantar fasciitis. The painful heel syndrome.
    The Journal of bone and joint surgery. American volume, 1975, Volume: 57, Issue:5

    Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Child; Female; Foot Diseases; Gout; Heel; Humans; Lu

1975
[On the question of drug-induced pseudo-LE syndrome: preliminary results in 58 cases (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1975, Jul-25, Volume: 100, Issue:30

    Topics: Acute Disease; Adult; Aged; Antibody Formation; Female; Humans; Lupus Erythematosus, Systemic; Male;

1975
S.L.E.-like reaction after phenylbutazone.
    Lancet (London, England), 1971, May-15, Volume: 1, Issue:7707

    Topics: Acute Disease; Adult; Antibodies, Antinuclear; Arthritis, Rheumatoid; Diagnosis, Differential; Femal

1971
[Rheumatic and pararheumatic diseases. Problems of diagnosis and therapy].
    Fortschritte der Medizin, 1973, Jul-19, Volume: 91, Issue:20

    Topics: Antineoplastic Agents; Arthritis, Rheumatoid; Collagen Diseases; Dermatomyositis; Humans; Lupus Eryt

1973
[Corticoid treatment of lupus].
    Medicina interna, 1967, Volume: 19, Issue:9

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Humans; Lupus Erythematosus, Systemic; Phenylb

1967
Anti-inflammatory drugs in rheumatic diseases.
    The Practitioner, 1974, Volume: 213, Issue:1276 SPEC

    Topics: Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Aspirin

1974
[Hydroxyproline excretion in urine in chronic connective tissue disease].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1970, Dec-01, Volume: 25, Issue:23

    Topics: Adrenocorticotropic Hormone; Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Collagen

1970
Which drugs for which rheumatic disorder?
    British medical journal, 1972, Apr-01, Volume: 2, Issue:5804

    Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Gold; Gout; Humans; Indomethacin; Lupus Erythematosus, S

1972
[Etilogy of SLE in connection with induction of antinuclear factors by various drugs].
    Verhandlungen der Deutschen Gesellschaft fur Rheumatologie, 1974, Volume: 3, Issue:0

    Topics: Antibodies, Antinuclear; DNA; DNA Repair; Humans; Isoniazid; Lupus Erythematosus, Systemic; Phenylbu

1974
[Drug-induced immune complex resembling syndomres].
    Ugeskrift for laeger, 1973, Oct-01, Volume: 135, Issue:40

    Topics: Adolescent; Adrenal Cortex Hormones; Aminosalicylic Acids; Contraceptives, Oral; Drug Combinations;

1973
EEG findings in juvenile rheumatoid arthritis and other connective tissue diseases in children.
    Acta paediatrica Scandinavica, 1974, Volume: 63, Issue:3

    Topics: Adolescent; Adrenal Cortex Hormones; Antimalarials; Arthritis, Juvenile; Brain; Child; Child, Presch

1974
Management and prognosis of systemic lupus erythematosus.
    Bulletin on the rheumatic diseases, 1967, Volume: 18, Issue:3

    Topics: Alkylating Agents; Antimalarials; Glucocorticoids; Humans; Immunosuppressive Agents; Indomethacin; K

1967
Anemia in rheumatoid arthritis.
    The Medical clinics of North America, 1968, Volume: 52, Issue:3

    Topics: Anemia; Arthritis, Rheumatoid; Chronic Disease; Female; Gastrointestinal Hemorrhage; Glucocorticoids

1968
Platelet reactions and immune processes. II. The inhibition of platelet aggregation by complement inhibitors.
    Thrombosis et diathesis haemorrhagica, 1969, Dec-31, Volume: 22, Issue:3

    Topics: Aldehydes; Blood Platelets; Catechols; Cell Membrane; Chloroquine; Colchicine; Collagen; Complement

1969
[Inflammation and anti-inflammatory agents. Non-steroid anti-inflammatory drugs. Management in dermatology].
    Nihon rinsho. Japanese journal of clinical medicine, 1968, Volume: 26, Issue:1

    Topics: Anti-Inflammatory Agents; Herpes Simplex; Humans; Indomethacin; Lupus Erythematosus, Systemic; ortho

1968